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LT2897956T - Nauji bicikliniai piridinonai - Google Patents

Nauji bicikliniai piridinonai

Info

Publication number
LT2897956T
LT2897956T LTEP13792085.6T LT13792085T LT2897956T LT 2897956 T LT2897956 T LT 2897956T LT 13792085 T LT13792085 T LT 13792085T LT 2897956 T LT2897956 T LT 2897956T
Authority
LT
Lithuania
Prior art keywords
novel bicyclic
pyridinones
bicyclic pyridinones
novel
bicyclic
Prior art date
Application number
LTEP13792085.6T
Other languages
English (en)
Inventor
Christopher William Am Ende
Michael Eric GREEN
Douglas Scott Johnson
Gregory Wayne KAUFFMAN
Christopher John O`DONNELL
Nandini Chaturbhai Patel
Martin Youngjin Pettersson
Antonia Friederike STEPAN
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Patrick Robert Verhoest
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of LT2897956T publication Critical patent/LT2897956T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
LTEP13792085.6T 2012-09-21 2013-09-06 Nauji bicikliniai piridinonai LT2897956T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (1)

Publication Number Publication Date
LT2897956T true LT2897956T (lt) 2017-01-10

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13792085.6T LT2897956T (lt) 2012-09-21 2013-09-06 Nauji bicikliniai piridinonai

Country Status (47)

Country Link
US (3) US8916564B2 (lt)
EP (1) EP2897956B1 (lt)
JP (1) JP5844018B2 (lt)
KR (1) KR101725696B1 (lt)
CN (1) CN104662021B (lt)
AP (1) AP2015008277A0 (lt)
AR (1) AR092628A1 (lt)
AU (1) AU2013319845B2 (lt)
BR (1) BR112015006436A2 (lt)
CA (1) CA2882386C (lt)
CL (1) CL2015000717A1 (lt)
CR (1) CR20150053A (lt)
CU (1) CU20150021A7 (lt)
CY (1) CY1118662T1 (lt)
DK (1) DK2897956T3 (lt)
DO (1) DOP2015000069A (lt)
EA (1) EA026668B1 (lt)
EC (1) ECSP15015594A (lt)
ES (1) ES2609987T3 (lt)
GE (1) GEP201706659B (lt)
GT (1) GT201500069A (lt)
HK (1) HK1206013A1 (lt)
HR (1) HRP20161558T1 (lt)
HU (1) HUE031248T2 (lt)
IL (1) IL237163A (lt)
IN (1) IN2015DN01119A (lt)
LT (1) LT2897956T (lt)
MA (1) MA37886B1 (lt)
MD (1) MD4583B1 (lt)
ME (1) ME02571B (lt)
MX (1) MX360599B (lt)
MY (1) MY181891A (lt)
NI (1) NI201500038A (lt)
NZ (1) NZ704863A (lt)
PE (1) PE20150686A1 (lt)
PH (1) PH12015500376B1 (lt)
PL (1) PL2897956T3 (lt)
PT (1) PT2897956T (lt)
RS (1) RS55426B1 (lt)
SG (1) SG11201501074WA (lt)
SI (1) SI2897956T1 (lt)
TN (1) TN2015000084A1 (lt)
TW (1) TWI500616B (lt)
UA (1) UA110688C2 (lt)
UY (1) UY35039A (lt)
WO (1) WO2014045156A1 (lt)
ZA (1) ZA201501195B (lt)

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UA110688C2 (uk) 2012-09-21 2016-01-25 Пфайзер Інк. Біциклічні піридинони
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US10246454B2 (en) 2013-01-17 2019-04-02 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
ES2742078T3 (es) * 2013-10-04 2020-02-13 Pfizer Piridonas bicíclicas novedosas como moduladores de gamma-secretasa
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
CR20160454A (es) * 2014-04-01 2016-12-06 Pfizer CROMENO Y 1,1 a,2,7b—TETRAHIDROCICLOPROPA[C]CROMENO PIRIDOPIRAZINADIONAS NOVEDOSAS
EA033423B1 (ru) * 2015-02-03 2019-10-31 Pfizer Циклопропанбензофуранилпиридопиразиндионы
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CN113164381A (zh) 2018-10-02 2021-07-23 频率医疗公司 有关耳用治疗剂的药物组合物及方法
WO2020210388A1 (en) 2019-04-08 2020-10-15 Frequency Therapeutics, Inc. Combination of chir99021 and valproic acid for treating hearing loss
CA3164134A1 (en) 2019-12-06 2021-06-10 Vertex Pharmaceuticals Incorporated Substituted tetrahydrofurans as modulators of sodium channels
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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CN114034792B (zh) * 2021-11-09 2024-06-25 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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