KR840000236A - 포유류의 국부용 제형의 수분 손실량을 극소화시키는 방법 - Google Patents
포유류의 국부용 제형의 수분 손실량을 극소화시키는 방법 Download PDFInfo
- Publication number
- KR840000236A KR840000236A KR1019820003025A KR820003025A KR840000236A KR 840000236 A KR840000236 A KR 840000236A KR 1019820003025 A KR1019820003025 A KR 1019820003025A KR 820003025 A KR820003025 A KR 820003025A KR 840000236 A KR840000236 A KR 840000236A
- Authority
- KR
- South Korea
- Prior art keywords
- formulation
- group
- water loss
- mammals
- salt
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims 6
- 241000124008 Mammalia Species 0.000 title claims 4
- 239000012049 topical pharmaceutical composition Substances 0.000 title claims 2
- 238000000034 method Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 4
- 239000013022 formulation composition Substances 0.000 claims 4
- -1 alkali metal salt Chemical class 0.000 claims 3
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 claims 2
- 229910052783 alkali metal Inorganic materials 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 159000000000 sodium salts Chemical group 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Paints Or Removers (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 포유류의 국부용 수분 함유 제형(劑刑)으로부터의 수분손실을 극소화시켜 수분손실을 방지함에 있어서, 다음 일반식의 N-치환-2-피톨리돈-4-카르복실산의 알칼리 금속염을 3 내지 30중량% 상기 제형에 혼합하는 것이 특징인 포유류의 국부용 제형의 수분손실량을 극소화시키는 방법.상기 식에서 R은 (C1-C5)알킬기 또는 (C1-C5)히드록시알킬기이다. 단, 히드록시기는 질소원자에 인접한 탄소원자에는 결합되지 않는다.
- 제1항에 있어서, 상기 제형이 약품 또는 화장품임을 특징으로 하는 방법.
- 제2항에 있어서, 상기 염이 나트륨염임을 특징으로 하는 방법.
- 제3항에 있어서, R가 메틸기임을 특징으로 하는 방법.
- 제3항에 있어서, R가 2-히드록시에틸기임을 특징으로 하는 방법.
- 다음 일반식의 화합물의 알칼리 금속염 3 내지 30중량%로 조성된 포유류의 국부용 수분함유 제헝 조성물.상기 식에서, R은 (C1-C5)알킬기 또는 (C1-C5)히드록시알킬기이다. 단, 히드록시기는 질소원자에 인접한 탄소원자에는 결합되지 않는다.
- 제6항에 있어서, 상기 제형이 약품 또는 화장품임을 특징으로 하는 제형 조성물.
- 제7항에 있어서, 상기 염이 나트륨염임을 특징으로 하는 제형 조성물.
- 제8항에 있어서, R가 메틸기임을 특징으로 하는 제형 조성물.
- 제8항에 있어서, R가 히드록시에틸기임을 특징으로 하는 제형 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28144581A | 1981-07-08 | 1981-07-08 | |
US281445 | 1981-07-08 | ||
US281.445 | 1981-07-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR840000236A true KR840000236A (ko) | 1984-02-18 |
KR860000272B1 KR860000272B1 (ko) | 1986-03-26 |
Family
ID=23077330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR8203025A KR860000272B1 (ko) | 1981-07-08 | 1982-07-07 | 화장품의 수분 손실량을 극소화시키는 방법 |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0069512B1 (ko) |
JP (1) | JPS5830330A (ko) |
KR (1) | KR860000272B1 (ko) |
AT (1) | ATE20181T1 (ko) |
AU (1) | AU532114B2 (ko) |
CA (1) | CA1200202A (ko) |
DE (1) | DE3271532D1 (ko) |
DK (1) | DK304682A (ko) |
ES (1) | ES513791A0 (ko) |
FI (1) | FI76925C (ko) |
GR (1) | GR77255B (ko) |
IE (1) | IE53203B1 (ko) |
IL (1) | IL66256A (ko) |
PH (1) | PH17648A (ko) |
PT (1) | PT75210B (ko) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0095849B1 (en) * | 1982-05-20 | 1987-09-09 | Stiksack STS S.A. | Plastics film and bags and sacks therefrom |
US4933463A (en) * | 1989-05-08 | 1990-06-12 | Gaf Chemicals Corporation | Polymerizable pyrrolidonyl oxazoline monomers, homopolymers and copolymers |
GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
US6669768B2 (en) | 2002-03-08 | 2003-12-30 | Eastman Kodak Company | Ink jet ink set |
US6669767B2 (en) | 2002-03-08 | 2003-12-30 | Eastman Kodak Company | Ink jet printing process |
DE102005006421A1 (de) | 2005-02-12 | 2006-08-24 | Clariant Produkte (Deutschland) Gmbh | Polymere und ihre Herstellung und Verwendung als Gashydratinhibitoren |
DE102007037016B4 (de) | 2007-08-06 | 2011-06-30 | Clariant International Limited | Verwendung von 1-Alkyl-5-oxo-pyrrolidin-3-carbonsäureestern als Gashydratinhibitoren mit verbesserter biologischer Abbaubarkeit |
DE102007037017A1 (de) | 2007-08-06 | 2009-02-19 | Clariant International Ltd. | 1-Alkyl-5-oxo-pyrrolidin-3-carbonsäureester mit verbesserter biologischer Abbaubarkeit |
DE102008003826B4 (de) | 2008-01-10 | 2010-07-22 | Clariant International Limited | Verwendung von Salzen als Korrosionsinhibitoren mit erhöhter biologischer Abbaubarkeit und verminderter Toxizität und diese Salze |
DE102008003828B3 (de) | 2008-01-10 | 2009-09-03 | Clariant International Limited | Verwendung von Salzen als Korrosionsinhibitoren mit erhöhter biologischer Abbaubarkeit und verminderter Toxizität und diese Salze |
FR2939309B1 (fr) | 2008-12-08 | 2010-12-17 | Oreal | Utilisation d'un derive ester de 2-pyrrolidinone 4-carboxy comme solvant dans les compositions cosmetiques ; compositions cosmetiques les contenant |
FR2939310B1 (fr) | 2008-12-08 | 2012-04-20 | Oreal | Compositions cosmetiques comprenant un derive ester de 2-pyrrolidinone 4-carboxy et un filtre lipophile triazine ; utilisation dudit derive comme solvant d'un filtre lipophile triazine |
FR2939315B1 (fr) | 2008-12-08 | 2011-01-21 | Oreal | Composition cosmetique contenant un derive de dibenzoylmethane et un compose ester de 2-pyrrolidinone 4-carboxy ; procede de photostabilisation du derive de dibenzoylmethane |
EP2496310A1 (en) * | 2009-11-05 | 2012-09-12 | L'Oréal | Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a merocyanin screening agent; use of said derivative as a solvent for a merocyanin screening agent |
WO2011054388A1 (en) * | 2009-11-05 | 2011-05-12 | L'oreal | Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a lipophilic screening agent; use of said derivative as a solvent for a benzophenone lipophilic screening agent |
FR2961101B1 (fr) | 2010-06-09 | 2013-01-25 | Oreal | Composition comprenant au moins une 2-pyrrolidone fonctionnalisee par un radical ester ou amide, et au moins un pigment ou un colorant direct pour la teinture des matieres keratiniques |
FR2961093A1 (fr) | 2010-06-09 | 2011-12-16 | Oreal | Composition cosmetique comprenant un polymere et un derive de 4-carboxy 2-pyrrolidinone, procede de traitement cosmetique et compose |
FR2961096B1 (fr) * | 2010-06-09 | 2013-01-18 | Oreal | Compositions cosmetiques comprenant un derive de 4- carboxy 2-pyrrolidinone et un filtre uv inorganique ; utilisation dudit derive comme agent dispersant d'un filtre inorganique |
FR2961094B1 (fr) * | 2010-06-09 | 2012-11-16 | Oreal | Utilisation de derive de 4-carboxy 2-pyrrolidinone dans une composition cosmetique comprenant une matiere particulaire |
CN101974042B (zh) * | 2010-10-29 | 2013-01-30 | 川渝中烟工业有限责任公司 | 五碳或六碳单糖-(e)-3-(呋喃-2-基)丙烯酸双酯类化合物及其制备方法和用途 |
CN101974039B (zh) * | 2010-10-29 | 2013-01-30 | 川渝中烟工业有限责任公司 | 五碳或六碳单糖-(e)-3-(呋喃-2-基)丙烯酸单酯类化合物及其制备方法和用途 |
CN101974040B (zh) * | 2010-10-29 | 2013-01-30 | 川渝中烟工业有限责任公司 | 五碳或六碳单糖-l-孟氧基乙酸单酯类化合物及其制备方法和用途 |
FR2977153B1 (fr) | 2011-06-29 | 2013-08-02 | Oreal | Composition cosmetique comprenant une huile fonctionnalisee et un solvant et procede de traitement cosmetique |
WO2013010590A1 (en) | 2011-07-21 | 2013-01-24 | L'oreal | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities |
DE102011119545A1 (de) | 2011-11-26 | 2013-05-29 | Clariant International Ltd. | Zusammensetzungen enthaltend ein Tensid aus der Gruppe der Pyrrolidoncarbonsäuren und deren Salzen und ein Betaintensid und deren Verwendung in der Kosmetik sowie in Wasch- und Reinigungsmitteln |
DE102012017739A1 (de) | 2012-09-07 | 2014-03-13 | Clariant International Ltd. | Verfahren zur Herstellung von N-substituierten Pyrrolidoncarbonsäureestern |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2757125A (en) * | 1952-05-16 | 1956-07-31 | Colgate Palmolive Co | N-higher alkyl-4-carboxy-2-pyrrolidones and compositions therewith |
FR1348617A (fr) * | 1961-12-12 | 1964-01-10 | Gillette Co | Compositions solides renfermant l'acide 2-pyrrolidone-5-carboxylique, ses dérivés et leurs sels comme agents humectants |
US3235457A (en) * | 1962-12-07 | 1966-02-15 | Gillette Co | Humectant |
GB1323061A (en) * | 1969-06-16 | 1973-07-11 | Castrol Ltd | Functional fluids and additives therefor |
US3803141A (en) * | 1972-08-14 | 1974-04-09 | Burdick & Jackson Labor Inc | 10-(1-substituted-3-pyrrolidylmethyl)phenothiazines |
US4253979A (en) * | 1979-02-05 | 1981-03-03 | Exxon Research & Engineering Co. | Lubricating grease composition containing pyrrolidone derivative as grease thickener |
JPS5835092B2 (ja) * | 1979-05-12 | 1983-07-30 | トヨタ自動車株式会社 | 耐アトリシヨン性粒状体の製造方法 |
-
1982
- 1982-06-25 EP EP82303312A patent/EP0069512B1/en not_active Expired
- 1982-06-25 DE DE8282303312T patent/DE3271532D1/de not_active Expired
- 1982-06-25 AT AT82303312T patent/ATE20181T1/de not_active IP Right Cessation
- 1982-06-30 IE IE1597/82A patent/IE53203B1/en unknown
- 1982-07-05 GR GR68647A patent/GR77255B/el unknown
- 1982-07-06 CA CA000406683A patent/CA1200202A/en not_active Expired
- 1982-07-07 KR KR8203025A patent/KR860000272B1/ko active
- 1982-07-07 PH PH27532A patent/PH17648A/en unknown
- 1982-07-07 ES ES513791A patent/ES513791A0/es active Granted
- 1982-07-07 DK DK304682A patent/DK304682A/da not_active Application Discontinuation
- 1982-07-07 AU AU85696/82A patent/AU532114B2/en not_active Ceased
- 1982-07-07 FI FI822414A patent/FI76925C/fi not_active IP Right Cessation
- 1982-07-07 PT PT75210A patent/PT75210B/pt not_active IP Right Cessation
- 1982-07-08 JP JP57119145A patent/JPS5830330A/ja active Granted
- 1982-07-08 IL IL66256A patent/IL66256A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
GR77255B (ko) | 1984-09-11 |
FI76925B (fi) | 1988-09-30 |
EP0069512B1 (en) | 1986-06-04 |
DK304682A (da) | 1983-01-09 |
FI822414A0 (fi) | 1982-07-07 |
EP0069512A2 (en) | 1983-01-12 |
ES8307744A1 (es) | 1983-08-01 |
ATE20181T1 (de) | 1986-06-15 |
JPS5830330A (ja) | 1983-02-22 |
IE53203B1 (en) | 1988-08-31 |
IE821597L (en) | 1983-01-08 |
CA1200202A (en) | 1986-02-04 |
FI822414L (fi) | 1983-01-09 |
IL66256A (en) | 1986-03-31 |
ES513791A0 (es) | 1983-08-01 |
KR860000272B1 (ko) | 1986-03-26 |
AU532114B2 (en) | 1983-09-15 |
JPH0157615B2 (ko) | 1989-12-06 |
DE3271532D1 (en) | 1986-07-10 |
AU8569682A (en) | 1983-02-03 |
FI76925C (fi) | 1989-01-10 |
PT75210B (en) | 1985-10-04 |
PH17648A (en) | 1984-10-18 |
EP0069512A3 (en) | 1984-03-07 |
IL66256A0 (en) | 1982-11-30 |
PT75210A (en) | 1982-08-01 |
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