KR20210074557A - Natural sterilizing pill - Google Patents
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- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
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- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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- A—HUMAN NECESSITIES
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- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/012—Deodorant compositions characterised by being in a special form, e.g. gels, emulsions
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
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Abstract
Description
본 고안은 일회용 천연 살균 알약의 제조방법에 관한 것으로, 특히 텀블러와 실험용 플라스크와 같은 살균 효과가 필요하지만 구석구석 세척이 어려운 도구들을 인체에 무해한 천연재료를 통해 손쉬운 세척과 함께 위생적으로 사용 할 수 있도록 해주는 것이다.The present invention relates to a method for manufacturing disposable natural sterilization pills, and in particular, tools that require sterilization effects such as tumblers and laboratory flasks, but which are difficult to clean in every nook and corner, can be used hygienically with easy cleaning through natural materials harmless to the human body. it will do
현대에는 다양한 종류의 바이러스가 생겨남에 따라 평소의 위생과 청결에 대한 사람들의 민감도가 증가하였고, 용품들에 대한 살균 및 소독이 강화되고 있는 추세이다.In modern times, as various types of viruses are generated, people's sensitivity to daily hygiene and cleanliness has increased, and the sterilization and disinfection of supplies is intensifying.
그런데 사람들이 자주 사용하는 텀블러는 가장 자주 살균세척 하여야하는 물품임에도 불구하고 구조상 혹은 여건상 제대로 살균 세척하지 못하는 경우가 빈번한다.However, although the tumbler that people use frequently is the item that needs to be sterilized and cleaned most often, it is often not possible to properly sterilize and clean it due to its structure or conditions.
또한 실험에서 사용하는 플라스크 또한 부반응을 줄이기위한 깔끔한 살균이 필요하지만 위와 동일하게 구조상의 어려움을 가지고 있다.In addition, the flask used in the experiment also needs clean sterilization to reduce side reactions, but it has the same structural difficulties as above.
본 발명은 텀블러나 실험용 플라스크 같은 주기적인 세척이 필요하지만 제품의 모양 혹은 여건상 꼼꼼한 세척의 어려움을 보다 간편화 하는 수단을 제공하고 있다The present invention provides a means to simplify the difficulty of meticulous cleaning due to the shape or condition of the product, although periodic cleaning such as a tumbler or laboratory flask is required.
본 발명인 천연 살균용 알약의 제조방법은 기본적으로 가루형태의 살균제로 안을 채우고 밖을 코팅하는 것으로 구체적으로 살균제는 탈취와 살균을 위한 베이킹 소다 10~12%중량과 구연산 80~85%중량, 향균과 탈취를 위한 레몬파우더 3~5%중량을 이용한 혼합원료가루를 건조 과립화에 의한 FDT의 제조방법을 이용하여, 베이킹 소다와 구연산을 미리 압축시키고, 그 결과 얻은 과립을 압축하여 신속하게 해될 수 있는 정제로 만든다. 이 공정에서, 0.2 내지 0.55 g/ml 밀도의 분말상 재료는 약 1.0 kN 내지 약 9.0 kN/cm 속도 범위의 힘을 가하는 것에 의해 미리 압축시켜 0.4 내지 0.75 g/ml 밀도로 증가시켜서 생성한 과립을 압축하여 정제로 만든다. 또한 캡슐알약 코팅단계에서The present invention's method for producing a natural sterilizing pill is basically filling the inside with a powdered disinfectant and coating the outside. Specifically, the disinfectant is 10 to 12% by weight of baking soda and 80 to 85% by weight of citric acid for deodorization and sterilization, and antibacterial and antibacterial agents. Using the manufacturing method of FDT by dry granulation of mixed raw material powder using 3 to 5% weight of lemon powder for deodorization, baking soda and citric acid are pre-compressed, and the resulting granules can be compressed to quickly disintegrate. made with tablets In this process, a powdered material with a density of 0.2 to 0.55 g/ml is pre-compressed by applying a force ranging from about 1.0 kN to about 9.0 kN/cm and increased to a density of 0.4 to 0.75 g/ml to compact the resulting granules. to make it into a tablet. In addition, in the capsule pill coating stage
캡슐을 신속하게 물에 용융시키기 위하여 붕해제를 소량 첨가하는데 이 붕해제는 카르복시메틸셀룰로오스, 녹말, 변성 녹말, 카르복시메틸화 녹말, 미세결정성 셀룰로오스 및 가능하게는 직접적으로 압축가능한 당과 같은 팽윤제이다. In order to rapidly dissolve the capsules in water, small amounts of disintegrant are added, which are swelling agents such as carboxymethylcellulose, starch, modified starch, carboxymethylated starch, microcrystalline cellulose and possibly directly compressible sugar. .
이 붕해제를 포함한 캡술알약 혼합물은 습식 과립화 방법에 의해 제조한다.The capsule tablet mixture containing this disintegrant is prepared by wet granulation method.
본 고안의 방식을 접목한 알약에 의하면, 세척 및 살균이 필요하지만 불편한 텀블러 및 플라스크 등을 간편하게 천연원료로 살균함으로써 무균상태로 이용할 수 있으며, 부가적으로 필요한 것은 물 뿐이므로 장소의 제약도 없이 어디서나 세척 및 살균이 가능하다는 효과가 있다According to the pill grafted with the method of the present invention, it can be used in a sterile state by simply sterilizing tumblers and flasks, which are inconvenient but inconvenient to wash and sterilize, with natural raw materials. It has the effect of being able to clean and sterilize
도 1 본 알약의 원료합성도
도 2 본 알약의 모형도
도 3 본 알약의 활용도Figure 1 Raw material synthesis diagram of this tablet
Figure 2 A schematic diagram of the present pill
Figure 3 Utilization of this pill
본 발명은 원료합성 단계와 코팅단계로 이루어져 있다The present invention consists of a raw material synthesis step and a coating step
<원료합성단계><Stage of synthesizing raw materials>
본 발명의 살균용 알약 원료제조단계는 베이킹 소다 10~12%중량과 구연산 80~85%중량, 향균과 탈취를 위한 레몬파우더 3~5%중량을 이용한 혼합원료가루를 건조 과립화에 의한 FDT의 제조방법을 이용하여, 베이킹 소다와 구연산을 미리 압축시키고, 그 결과 얻은 과립을 압축하여 신속하게 해될 수 있는 정제로 만든다. 이 공정에서, 0.2 내지 0.55 g/ml 밀도의 분말상 재료는 약 1.0 kN 내지 약 9.0 kN/cm 속도 범위의 힘을 가하는 것에 의해 미리 압축시켜 0.4 내지 0.75 g/ml 밀도로 증가시켜서 생성한 과립을 압축하여 정제로 만든다.The manufacturing step of the raw material for sterilization pills of the present invention consists of dry granulation of mixed raw material powder using 10 to 12% weight of baking soda, 80 to 85% weight of citric acid, and 3-5% weight of lemon powder for antibacterial and deodorization Using the manufacturing method, baking soda and citric acid are pre-compressed, and the resulting granules are compressed into rapidly disintegrating tablets. In this process, a powdered material with a density of 0.2 to 0.55 g/ml is pre-compressed by applying a force ranging from about 1.0 kN to about 9.0 kN/cm and increased to a density of 0.4 to 0.75 g/ml to compact the resulting granules. to make it into a tablet.
원료들의 효과에 대해 살펴보자면 구연산(citric acid)은 색 또는 무색투명 결정성 분말로서, 식기류 또는 도마나 칼등 조리기구 목적으로 흔히 사용되고 있고, 식품의약품안전청에서도 식품용 기구 등의 살균소독에 사용할 수 있도록 하여 그 안전성이 이미 인정되어 있으며, 미국 및 EU에서도 식품에 직접 사용되는 식품첨가물 이외에 살균소독제로 널리 사용되고 있다.If we look at the effects of raw materials, citric acid is a colorless or colorless transparent crystalline powder, which is commonly used for tableware or cooking utensils such as cutting boards and knives. Therefore, its safety has already been recognized, and it is widely used as a sterilizing and disinfecting agent in addition to food additives used directly in food in the US and EU.
그리고 베이킹소다는 바닷물이 증발하고 남은 탄산수소나트륨에서 불순물을 제거해 만든 천연 미네랄이다. 오염 물질인 기름때와 찌든 때 먼지 등을 말끔히 사라지게 하고 탈취 효과가 있다.And baking soda is a natural mineral made by removing impurities from sodium bicarbonate remaining after evaporation of sea water. It has a deodorizing effect and cleanly removes oil and dirt, which are pollutants.
다음 레몬 또한 소독과 탈취 방향의 목적으로 매우 널리 쓰이는 천연 재료이다.The next lemon is also a very popular natural ingredient for disinfecting and deodorizing purposes.
<알약 코팅단계><Pill coating step>
본 발명의 알약 코팅단계는 셀룰로오스를 베이스로 캡슐을 신속하게 물에 용융시키기 위하여 붕해제를 소량 첨가한다.In the tablet coating step of the present invention, a small amount of a disintegrant is added to quickly melt the capsule in water based on cellulose.
붕해제로는 카르복시메틸셀룰로오스, 녹말, 변성 녹말, 카르복시메틸화 녹말, 미세결정성 셀룰로오스 및 가능하게는 직접적으로 압축가능한 당과 같은 팽윤제를 이용한다. As disintegrating agents, swelling agents such as carboxymethylcellulose, starch, modified starch, carboxymethylated starch, microcrystalline cellulose and possibly directly compressible sugars are used.
이 붕해제를 포함한 캡술알약 코팅물은 습식 과립화 방법에 의해 제조한다.The capsule tablet coating containing this disintegrant is prepared by wet granulation method.
습식 과립화 방법이란 활성 성분 및 1개 이상의 수성 당을 0.01 내 지 0.2 톤/cm2의 압력에서 압축시킨후 이 정제를 습윤시키고 건조시켜 20 내지 40%의 다공성을 생성한다. 제제중의 활성성분은 30% 미만이어야한다. 제제중의 유한 당은 에리트리톨, 크실리톨 및 만니톨을 포함 한다. 정제 제조 장치는 회전식 타정기(punch press), 정제를 수송하기 위한 릴레이 컨베이어, 습윤실, 건조실 및 전 달 컨베이어를 포함한다. 습윤실에서, 조건은 정제가 45℃95% 상대습도에서 60초간 습윤처리되도록 설정된다.In the wet granulation process, the active ingredient and one or more aqueous sugars are compressed at a pressure of 0.01 to 0.2 tons/cm 2 , followed by wetting and drying of the tablets to produce a porosity of 20-40%. The active ingredient in the formulation should be less than 30%. Finite sugars in the formulation include erythritol, xylitol and mannitol. The tablet manufacturing apparatus includes a rotary punch press, a relay conveyor for transporting tablets, a wet chamber, a drying chamber and a transfer conveyor. In the wet chamber, conditions are set such that the tablets are wetted at 45° C. 95% relative humidity for 60 seconds.
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Citations (4)
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KR20050016301A (en) | 2003-05-07 | 2005-02-21 | 아키나, 인크. | Highly plastic granules for making fast melting tablets |
KR20130140390A (en) | 2012-06-14 | 2013-12-24 | 김동찬 | Natural germicide composition and methods for manufacturing a natural germicide |
KR20150080934A (en) | 2013-12-06 | 2015-07-13 | 광주과학기술원 | Control method and system for wireless access network |
KR20170022552A (en) | 2015-08-21 | 2017-03-02 | 주식회사 서흥 | Manufacturing method for soft capsule containing solid formulation as core ingredient |
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Publication number | Priority date | Publication date | Assignee | Title |
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KR20050016301A (en) | 2003-05-07 | 2005-02-21 | 아키나, 인크. | Highly plastic granules for making fast melting tablets |
KR20130140390A (en) | 2012-06-14 | 2013-12-24 | 김동찬 | Natural germicide composition and methods for manufacturing a natural germicide |
KR20150080934A (en) | 2013-12-06 | 2015-07-13 | 광주과학기술원 | Control method and system for wireless access network |
KR20170022552A (en) | 2015-08-21 | 2017-03-02 | 주식회사 서흥 | Manufacturing method for soft capsule containing solid formulation as core ingredient |
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