KR20200118823A - 펜타아자 마크로시클릭 고리 복합체 및 백금-기재 항암제를 사용한 조합 암 요법 - Google Patents

펜타아자 마크로시클릭 고리 복합체 및 백금-기재 항암제를 사용한 조합 암 요법 Download PDF

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Publication number: KR20200118823A
Authority: KR; South Korea
Prior art keywords: platinum; anticancer agent; based anticancer; pentaaza macrocyclic; macrocyclic ring
Prior art date: 2018-01-31

Application number

KR1020207024560A

Other languages

English (en)

Korean (ko)

Inventor

제프리 엘. 킨

데니스 피. 라일리

로버트 에이. 비어즐리

마이클 딘 스토리

크란티 아스호크 마푸스카

주니어 더글라스 알. 스피츠

브라이언 쥐. 앨런

앤드류 블레이크 데이비스

다이애나 제페다 오로즈코

Original Assignee

갈레라 랩스, 엘엘씨

보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-01-31

Filing date

2019-01-31

Publication date

2020-10-16

2019-01-31 Application filed by 갈레라 랩스, 엘엘씨, 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 filed Critical 갈레라 랩스, 엘엘씨

2020-10-16 Publication of KR20200118823A publication Critical patent/KR20200118823A/ko

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BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title claims abstract description 667
239000002246 antineoplastic agent Substances 0.000 title claims abstract description 362
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DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims description 123
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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WO2017027728A1 (en)	2015-08-11	2017-02-16	Galera Labs, Llc	Pentaaza macrocyclic ring complexes possessing oral bioavailability
JP2019131508A (ja) *	2018-01-31	2019-08-08	ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａＬａｂｓ，Ｌｌｃ	ペンタアザ大環状環複合体および白金を基にした抗癌剤による組み合わせ癌療法
WO2024026273A1 (en) *	2022-07-25	2024-02-01	Galera Labs, Llc	Therapy for reduced ototoxicity from chemotherapeutic agent with pentaaza macrocyclic ring complex

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EP2760874A4 (en) *	2011-09-26	2015-04-08	Galera Therapeutics Llc	METHOD FOR THE TREATMENT OF ILLNESSES
BR112018072560A2 (pt) *	2016-05-03	2019-02-19	Galera Labs, Llc	terapia de combinação para tratamento do câncer

2019
- 2019-01-31 CA CA3090129A patent/CA3090129A1/en active Pending
- 2019-01-31 JP JP2020541809A patent/JP2021512110A/ja active Pending
- 2019-01-31 AU AU2019215032A patent/AU2019215032A1/en active Pending
- 2019-01-31 BR BR112020015520-9A patent/BR112020015520A2/pt not_active Application Discontinuation
- 2019-01-31 KR KR1020207024560A patent/KR20200118823A/ko unknown
- 2019-01-31 US US16/965,476 patent/US20210338686A1/en active Pending
- 2019-01-31 EA EA202091832A patent/EA202091832A1/ru unknown
- 2019-01-31 CN CN201980019662.4A patent/CN111902147A/zh active Pending
- 2019-01-31 SG SG11202007317XA patent/SG11202007317XA/en unknown
- 2019-01-31 MX MX2020008028A patent/MX2020008028A/es unknown
- 2019-01-31 IL IL276407A patent/IL276407B1/en unknown
- 2019-01-31 EP EP19747505.6A patent/EP3746085A4/en active Pending
- 2019-01-31 WO PCT/US2019/016071 patent/WO2019152661A1/en unknown
2020
- 2020-07-30 PH PH12020551176A patent/PH12020551176A1/en unknown
2024
- 2024-02-09 JP JP2024018847A patent/JP2024054295A/ja active Pending

Also Published As

Publication number	Publication date
JP2024054295A (ja)	2024-04-16
CN111902147A (zh)	2020-11-06
US20210338686A1 (en)	2021-11-04
IL276407A (en)	2020-09-30
MX2020008028A (es)	2020-12-11
WO2019152661A1 (en)	2019-08-08
AU2019215032A1 (en)	2020-09-10
JP2021512110A (ja)	2021-05-13
EA202091832A1 (ru)	2021-01-11
SG11202007317XA (en)	2020-08-28
IL276407B1 (en)	2024-09-01
EP3746085A1 (en)	2020-12-09
CA3090129A1 (en)	2019-08-08
EP3746085A4 (en)	2022-03-09
PH12020551176A1 (en)	2021-06-07
BR112020015520A2 (pt)	2021-02-02

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