KR20190087105A - Coating composition for infection control of tattoo area and method of preparing the same - Google Patents

Abstract

The present invention relates to a coating composition for preventing the infection of tattooed area and a method of manufacturing the same, with the formation of a thin film by spraying the composition around a tattooed area on the skin after getting a tattoo in order to block the penetration of bacteria and the like through the tattooed area. It is also possible to further improve the stability of a tattooing process by improving the skin condition due to antibacterial, antioxidant, skin moisturizing, sun protection and skin soothing effects.

Description

TECHNICAL FIELD [0001] The present invention relates to a coating composition for preventing tattoo site infection and a method for producing the same,

The present invention forms a film by spraying a tattoo around the tattooed skin after tattooing to prevent the penetration of bacteria and the like through the tattoo area, and to prevent the penetration of bacteria and the like through antibacterial / antioxidant, skin moisturizing, The present invention relates to a coating composition for preventing infection of a tattoo site and a method for producing the same.

A tattoo refers to the insertion of colored dyes into the deep layers of the skin, or dermis, by inscribing letters, patterns, or pictures by hurting people's skin.

The present invention is to prevent infection by bacteria and the like after tattooing. The composition is sprayed around the tattooed skin to form a coating film, thereby preventing primary bacteria from penetrating, and further, antibacterial and antioxidant , A skin moisturizing function, an ultraviolet shielding function, and a skin soothing effect.

In connection with the present invention, there has been disclosed a technique for a film-forming composition for skin coating and a magnetizing device disclosed in Korean Patent Laid-Open No. 10-2005-0091651 (published on September 15, 2005) And it is not suitable to be applied as a composition for prevention of tattoo site infection and improvement of skin condition to be proposed in the present invention, for protecting against physical bite and controlling external volatilization of a directional substance and inducing natural healing power to the affected part.

Korean Patent Laid-Open No. 10-2005-0091651 (Publication date 2005.09.15)

The present invention relates to a method for preventing the infiltration of germs and the like around a tattoo area by forming a film thin film by spraying the tattooed skin around the tattooed skin after the tattoo operation, The present invention provides a coating composition for preventing infection of a tattoo site and a method of manufacturing the same.

In order to achieve the above object,

According to the present invention,

Water (a) 89.0 to 95.0 wt%;

Polyvinyl alcohol (b) 3.0 to 6.0 wt%;

Dimethicone (c) 1.0 to 3.0 wt%;

Ethylhexylglycerin (d) 0.1 to 2.0 wt%;

1,2-Hexanediol (e) 0.1 to 2.0 wt%;

(F) 0.1-0.5 wt% of the thickener of hydroxyethylcellulose;

The mixture was added to 20 to 50 times of distilled water and extracted with shaking at 35 to 39 ° C at 150 to 300 rpm for 1 to 48 hours. 10 to 50 wt% of a crude oil extract prepared by concentrating the filtrate obtained by filtering the obtained solution with a filter with a rotary evaporator,

After freeze-drying, the milled powdery starch powder was added in a ratio of 1:10 to 30 by weight with water, and the resulting solution was extracted at 28 to 32 ° C for 22 to 26 hours. The resulting solution was centrifuged at 10,000 to 13,000 The mixture was centrifuged at rpm for 15 to 30 minutes, and the supernatant was filtered with a filter. The filtrate was concentrated with a rotary evaporator (Rotavapor), and 10 to 50 wt%

A series of processes of immersing the herpes zoster with ethanol at a weight ratio of 1: 5 to 15 at a temperature of 23 to 27 ° C for 20 to 30 hours, separating the supernatant and the precipitate is repeated 2 to 4 times, and the obtained solution is centrifuged The mixture was centrifuged at 10,000 to 13,000 rpm for 15 to 30 minutes. The supernatant was filtered with a filter, and the filtrate was concentrated with a rotary evaporator to obtain 100 wt% (G) 0.1 ~ 5.0 wt% of natural antioxidant and antimicrobial extract;

The mixture of crushed bamboo shoots and ethanol was mixed at a weight ratio of 1: 5 to 20, and the resultant solution was subjected to sonication extraction. The resulting solution was filtered, and the filtrate was concentrated using a rotary evaporator. 50 wt%

The mixture of water stem and leaf were mixed at the same weight ratio and then dried at 63 to 68 ° C for 6 to 10 hours so that the water content was 5 wt% or less. The dried water mixture was mixed with 80% ethanol at a weight ratio of 1: 5 to 20 And the mixture is refluxed and cooled for 2 to 4 hours in a water bath at 75 to 85 ° C for 2 to 4 times. The obtained solution is filtered, and the filtrate is concentrated by a rotary evaporator (Rotavapor) 10 to 50 wt% of the extract,

The mixture of sea cucumber and ethanol in a weight ratio of 1: 5 to 15, and the solution extracted from the shaker incubator at 25 to 28 ° C for 20 to 30 hours at 130 to 170 rpm is centrifuged at 7,500 to 8,500 rpm for 15 to 25 minutes 0.1 to 5.0 wt% of a 100 wt% natural moisturizing extract (h) composed of 10 to 50 wt% of a sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotary evaporator (Rotavapor);

And 10 to 35 wt% of rhizome and 10 to 35 wt% of rhizome were mixed and then ground, and the ground mixture was mixed with 90% methanol and 1: 5 to 20 wt% And the resulting solution is filtered using a filter. The resulting filtrate is concentrated using a rotary evaporator (Rotavapor), and the filtrate is filtered through a rotary evaporator (Rotavapor) (A + b + c + d + e + f + g + h + i) of the blocking extract (i) in an amount of 0.1 to 5.0 wt%;

And

Preparing a natural antioxidant and antimicrobial extract by mixing 10 to 50 wt% of a corn oil extract, 10 to 50 wt% of a perennial plant extract, and 10 to 50 wt% of a perennial plant extract,

Preparing a natural moisturizing extract by mixing 10 to 50 wt% of a ginseng extract, 10 to 50 wt% of a water extract, 10 to 50 wt% of a water extract, and 10 to 50 wt% of a sea cucumber extract,

Preparing a natural ultraviolet screening extract from a mixture of 10 to 35 wt% red ginseng, 10 to 35 wt% of rhizome, 10 to 35 wt% of rhubarb, and 10 to 35 wt% of visa,

Wherein the emulsion contains from 89.0 to 95.0 wt% of purified water, 3.0 to 6.0 wt% of polyvinyl alcohol, 1.0 to 3.0 wt% of dimethicone, 0.1 to 2.0 wt% of ethylhexyl glycerin, 0.1 to 5.0 wt% of a natural antioxidant / antibacterial extract, 0.1 to 5.0 wt% of a natural moisturizing extract, 0.1 to 5 wt% of a natural antioxidant / antimicrobial extract, 0.1 to 2.0 wt% of a 1,2-hexanediol, 0.1 to 5.0 wt% of an ultraviolet screening extract to form a mixture for a coating composition;

Stirring the mixture at 500 rpm to 1,000 rpm for 1 to 3 hours,

The mixture for coating composition having been subjected to the stirring process is placed in a net of 200 to 500 mesh to pressurize and filtrate the coating composition.

The coating composition for preventing tattoo site infection according to the present invention has the following effects.

first. After tattooing, it is easily sprayed around the tattoo area to form a film film on the tattoo area, preventing bacteria from penetrating into the human body through the tattoo area.

second. It has antioxidant and antimicrobial functions and has the effect of suppressing skin aging and skin pollution.

third. It has an effect of improving skin health condition by skin moisturizing and ultraviolet shielding function.

fourth. By giving skin soothing effect, skin irritation after tattooing can be minimized.

The details of the technical construction according to the present invention will be described.

As described above,

The coating composition for preventing tattoo site infection according to the present invention comprises

Water (a) 89.0 to 95.0 wt%;

Polyvinyl alcohol (b) 3.0 to 6.0 wt%;

Dimethicone (c) 1.0 to 3.0 wt%;

Ethylhexylglycerin (d) 0.1 to 2.0 wt%;

1,2-Hexanediol (e) 0.1 to 2.0 wt%;

(F) 0.1-0.5 wt% of the thickener of hydroxyethylcellulose;

The mixture was added to 20 to 50 times of distilled water and extracted with shaking at 35 to 39 ° C at 150 to 300 rpm for 1 to 48 hours. 10 to 50 wt% of the extract of corn oil, prepared by concentrating the filtrate obtained by extracting the obtained solution with a filter using a rotary evaporator,

After freeze-drying, the milled powdery starch powder was added in a ratio of 1:10 to 30 by weight with water, and the resulting solution was extracted at 28 to 32 ° C for 22 to 26 hours. The resulting solution was centrifuged at 10,000 to 13,000 The mixture was centrifuged at rpm for 15 to 30 minutes, and the supernatant was filtered with a filter. The filtrate was concentrated with a rotary evaporator (Rotavapor), and 10 to 50 wt%

A series of processes of immersing the herpes zoster with ethanol at a weight ratio of 1: 5 to 15 at a temperature of 23 to 27 ° C for 20 to 30 hours, separating the supernatant and the precipitate is repeated 2 to 4 times, and the obtained solution is centrifuged The mixture was centrifuged at 10,000 to 13,000 rpm for 15 to 30 minutes. The supernatant was filtered with a filter, and the filtrate was concentrated with a rotary evaporator to obtain 100 wt% (G) 0.1 ~ 5.0 wt% of natural antioxidant and antimicrobial extract;

The mixture of crushed bamboo shoots and ethanol was mixed at a weight ratio of 1: 5 to 20, and the resultant solution was subjected to sonication extraction. The resulting solution was filtered, and the filtrate was concentrated using a rotary evaporator. 50 wt%

The mixture of water stem and leaf were mixed at the same weight ratio and then dried at 63 to 68 ° C for 6 to 10 hours so that the water content was 5 wt% or less. The dried water mixture was mixed with 80% ethanol at a weight ratio of 1: 5 to 20 And the mixture is refluxed and cooled for 2 to 4 hours in a water bath at 75 to 85 ° C for 2 to 4 times. The obtained solution is filtered, and the filtrate is concentrated by a rotary evaporator (Rotavapor) 10 to 50 wt% of the extract,

The mixture of sea cucumber and ethanol in a weight ratio of 1: 5 to 15, and the solution extracted from the shaker incubator at 25 to 28 ° C for 20 to 30 hours at 130 to 170 rpm is centrifuged at 7,500 to 8,500 rpm for 15 to 25 minutes 0.1 to 5.0 wt% of a 100 wt% natural moisturizing extract (h) composed of 10 to 50 wt% of a sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotary evaporator (Rotavapor);

And 10 to 35 wt% of rhizome and 10 to 35 wt% of rhizome were mixed and then ground, and the ground mixture was mixed with 90% methanol and 1: 5 to 20 wt% And the resulting solution is filtered using a filter. The resulting filtrate is concentrated using a rotary evaporator (Rotavapor), and the filtrate is filtered through a rotary evaporator (Rotavapor) (A + b + c + d + e + f + g + h + i) of the blocking extract (i) of 0.1 to 5.0 wt%;

The polyvinyl alcohols (polyvinyl alcohols) are generally prepared by saponification of vinyl acetate monomers by radical polymerization. PAV has a unique property of water solubility in synthetic polymers. White powder having a specific gravity of 0.3 to 0.7. Degree of saponification DS is an important factor determining the properties of PVA. When the ignition degree is high, the hydrogen bond between the molecules is strong and the melting point is high and it is difficult to dissolve in water. It is swollen or dissolved in hot water (75 ° C or higher), but is insoluble in cold water. In the present invention, the polyvinyl alcohol serves to form a film-like thin film together with dimethicone.

When the content of the polyvinyl alcohol is less than 3.0 wt%, it is difficult to form the film thin film properly. When the content of the polyvinyl alcohol exceeds 6.0 wt%, it is unnecessary because it is unnecessarily used. Therefore, the polyvinyl alcohol (Polyvinyl alcohol) is preferably limited to a range of 3.0 to 6.0 wt% based on the total weight of the composition.

Dimethicone is a closed type moisturizer. It is applied to cosmetics and gives good feel to the skin. It does not give a sticky feeling to the skin and protects the skin by forming a film.

When the amount of dimethicone having such a function is less than 1.0 wt%, the skin protection function due to the formation of the film is deteriorated. When the amount of dimethicone is more than 3.0 wt%, the content of the other components is decreased, The dimethicone is preferably used in an amount of 1.0 to 3.0 wt% based on the total weight of the composition.

Ethylhexylglycerin is a glyceryl ether which is an organic compound component and is one kind of glycerin, which increases the antibacterial activity. Therefore, in the present invention, it is used as a preservative to prevent contamination with bacteria or germs of cosmetics. When the amount is less than 0.1 wt%, the functionality as a preservative is insignificant. When the amount exceeds 2.0 wt% Therefore, the amount of ethylhexyl glycerin is preferably limited to a range of 0.1 to 2.0 wt% based on the total weight of the composition.

The 1,2-hexanediol is also called 1,2-dihydroxyhexane, and has a structure in which the first and second alcohol groups of the linear alkyl chain are attached to each other. It has a surfactant structure with both hydrophobic and hydrophilic groups, and is an odorless substance. It is a moisturizer and safe preservative for use.

When the amount of 1,2-hexanediol used is less than 0.1 wt%, it is difficult to properly function as preservative and preservative. When the amount of 1,2-hexanediol is more than 2.0 wt%, the use of 1,2- Therefore, the 1,2-hexanediol is preferably used in an amount of 0.1 to 2.0 wt% based on the total weight of the composition.

Hydroxyethylcellulose, which is a thickener, is used to control the viscosity of a coating composition for preventing infection. When the amount is less than 0.1 wt%, the viscosity control function is insufficient. When the amount is more than 0.5 wt% The amount of hydroxyethylcellulose to be used is preferably limited to a range of 0.1 to 0.5 wt% based on the total weight of the composition.

The amount of the natural antioxidant / antibacterial extract is limited within a range of 0.1-5.0 wt% with respect to the total weight of the composition. When the amount of the natural antioxidant / antibacterial extract is less than 0.1 wt%, the antioxidant / antibacterial function is insignificant and exceeds 5.0 wt% , The content of the other components may be decreased to lower the functionality such as thin film formation, moisturizing and ultraviolet ray shielding. Therefore, the amount of the natural antioxidant / antibacterial extract should preferably be limited within the above-mentioned range.

The natural antioxidant and antimicrobial extracts are prepared by mixing 10 to 50 wt% of a crude oil extract, 10 to 50 wt% of a perennial herb extract, and 10 to 50 wt% of a perennial herb extract.

More specifically, a mixture of 50 wt% of the extract of corn oil, 25 wt% of the tsunami extract, and 25 wt% of the extract of the perennial plant is used.

The jujube fruit is a jujube-shaped, round shape with a length of about 1.5 cm and is called jujube candle because of its distinctive odor, sour taste and slight sweetness in its jujube shaped purple-purple appearance with rough wrinkles.

Iridoid glycosides such as gallicacid, malic acid, tartaric acid, ursolic acid, morroniside, loganin, sweroside and methylmonorroniside have been reported as the main chemical components of the fruit, and tellimagrandin 1,2, 1,2,3-tri- glucose, 1,2,6-tri-O-galloyl-β-D-glucose, 1,2,3,6-tetra-O-galloyl-β-D-glucose, gemini D, Cornusin AG , Tannins such as 2,3-di-O-galloyl-D-glucose and 1,7-di-O-galloyl-D-sedoheptullose have been reported. Among them, malicacid, tartaricacid, etc. show sour taste, loganin and sweroside show bitter tastes, and gallicacid and tannin flavor have a bitter taste.

The extract of corn oil is prepared by mixing dried corn oil and leaves at the same weight ratio to form a mixture. The mixture is added to 20 to 50 times of distilled water, and then the mixture is stirred at 35 to 39 ° C at 150 to 300 rpm for 1 to 48 hours The solution obtained by shaking extraction and extraction is filtered with a filter, and the filtrate is concentrated with a rotary evaporator.

More specifically, the mixture is dried by drying at 70 ° C to prepare a mixture by mixing the dried fruit with the moisture content of 3 wt% or less and the leaves at a weight ratio of 1: 1.

The mixture is added to distilled water, and the mixture is added so that the mixing ratio of the mixture and distilled water is 1:20 by weight. And shake-extracted at 37 ° C and 200 rpm for 40 hours.

The solution obtained by shaking extraction is filtered through a filter (Whatman No.2 filter paper), and the filtrate is concentrated by a rotary evaporator (Rotavapor).

The cactus is a perennial plant belonging to Cactacea, Opuntioideae and Opuntia, which are similar to the palms of a palm. It contains polyphenol compounds and is highly antioxidant. It contains important nutrients such as minerals, vitamins, dietary fiber, amino acids and polysaccharides. The fruit and stem of cactus have long been used for the purpose of constipation treatment, diuretic effect, activation of intestinal funnel, and appetite promotion. Stem is used as folk medicine for skin disease, rheumatism and burn treatment.

The citrus fruit extract is prepared by adding lyophilized powdered wheat flour to water at a ratio of 1:10 to 30 by weight and then extracting the mixture at 28 to 32 ° C for 22 to 26 hours. The obtained solution is centrifuged Centrifuging at 10,000 to 13,000 rpm for 15 to 30 minutes, filtering the supernatant through a filter, and concentrating the filtrate with a rotary evaporator.

More specifically, the lyophilized fruit is milled to prepare a powder. The above millet seed powder is added to water so that the mixing ratio of the millet seed powder and water is 1:20 by weight. The solution obtained by extraction at 30 DEG C for 24 hours is centrifuged at 12,000 rpm for 20 minutes using a centrifuge. Centrifuge the supernatant with a filter (Whatman No.2 filter paper), and concentrate the filtrate on a rotary evaporator.

Staphylococcus aureus is a perennial herbaceous plant belonging to Saururus chinensis, which contains the leaves, stems, flowers and roots of a drug mobil (Houttuynia cordatathunb). The name of the fish is the name given to fish smell in the stem and leaf. The nature of the ecstasy is limited, the taste is very high, and it selectively acts on the lungs and liver. Pharmacological actions include antimicrobial, anti-inflammatory, diuretic, and anti-viral effects.

The above-mentioned extract of Horseshoe chrysanthemum is obtained by immersing the Horseshoe chrysanthemum with ethanol at a weight ratio of 1: 5 ~ 15 at 23 ~ 27 캜 for 20 ~ 30 hours, and then separating the supernatant and the precipitate by repeating 2 ~ Centrifuge the mixture at 10,000 ~ 13,000 rpm for 15-30 minutes using a centrifuge, filter the supernatant with a filter, and concentrate the filtrate with a rotary evaporator.

More specifically, the perennial herb is added to 90% ethanol, and the mixture is mixed so that the mixing ratio of the perch and 90% ethanol is 1:10 by weight. After immersing at 25 ° C for 25 hours, the supernatant and precipitate were separated, and the same procedure was repeated three times using the supernatant. The solution thus obtained is centrifuged at 12,000 rpm for 20 minutes using a centrifuge. Centrifuge the supernatant with a filter (Whatman No.2 filter paper), and concentrate the filtrate on a rotary evaporator.

The amount of the natural moisturizing extract to be used is limited within a range of 0.1 to 5.0 wt% with respect to the total weight of the composition. When the amount of the natural moisturizing extract is less than 0.1 wt%, the moisturizing function is insufficient. When the amount is more than 5.0 wt% The content of the other components may be decreased to lower the functionality such as thin film formation, antimicrobial / antioxidant, ultraviolet shielding, etc. Therefore, the amount of the natural moisturizing extract is preferably limited within the above-mentioned range.

The natural moisturizing extract is composed of 10-50 wt% of ginseng extract, 10-50 wt% of water extract and 10-50 wt% of sea cucumber extract.

More specifically, a mixture composed of 35 wt% of ginseng extract, 35 wt% of water extract and 30 wt% of sea cucumber extract is used.

Bokyeong is a type of mushroom belonging to the mushroom family. The main components of Byeongryeong are carbohydrate, water, crude fiber, minerals and trace amount of protein. Among the carbohydrates, pachyman is the most abundant carbohydrate. Pachymic acid, tumulosic acid, dehydrotumulosic acid, ergosterol, eburicoic acid, dehydroeburicoic acid, trametenolic acid .

The bamboo extract was prepared by mixing the bran gum and the ethanol at a weight ratio of 1: 5 to 20 by weight, filtering the obtained solution by sonication extraction, and concentrating the filtrate with a rotary evaporator (Rotavapor) do.

More specifically, the pulverized bamboo shoots are added to 90% ethanol, and the pulverized bamboo shoots and 90% ethanol are mixed at a mixing ratio of 1:10 by weight. Ultrasonic waves of 60 kHz are generated for 30 minutes and then extracted at room temperature for 60 hours. The extracted solution is filtered through a filter (Whatman No.2 filter paper), and the filtrate is concentrated on a rotary evaporator (Rotavapor).

Water lily (Nymphaea tetragona Georgi var.) Is a dicotyledonous plant, buttercup, and water lily. Hydrolysable tannin and its constituents geraniin, 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) and Ellagic acid were isolated. Amino acids, and Alkaroid have been reported.

The water lily extracts were prepared by mixing the water lily stem and the leaves at the same weight ratio and then drying at 63 to 68 ° C for 6 to 10 hours so that the water content would be 5 wt% or less. The dried water lily mixture was mixed with 80% To 20 weight ratio and reflux cooling extraction for 2 to 4 hours in a water bath at 75 to 85 ° C was repeated 2 to 4 times to filter the obtained solution, and the filtrate was concentrated with a rotary evaporator (Rotavapor) .

More specifically, the mixture is prepared by mixing water-stem and leaf in a weight ratio of 1: 1. The mixture is dried at 65 DEG C for 6 to 10 hours to adjust the moisture content to 5 wt% or less. The dried watery mixture is added to 80% ethanol, and the watery mixture and the 80% ethanol are mixed at a ratio of 1:10 by weight. The process of refluxing cooling extraction for 3 hours in a water bath at 80 캜 is repeated three times. The resulting solution is filtered through Whatman No. 2 filter paper, and the filtrate is concentrated on a rotary evaporator (Rotavapor).

Sea cucumber is a category of echinoderms and belongs to sea cucumber. It is called sea cucumber, sea cucumber, and light cucumber. In addition to the moisturizing function, the sea cucumber enhances the immune function of the human mononuclear cells and macrophages, and is effective in wound healing. In particular, calcium and iron are sufficient to form teeth and skeleton, normal contraction of muscles It plays a role in regulating relaxation.

The sea cucumber extracts were prepared by mixing sea cucumber and ethanol in a weight ratio of 1: 5 to 15, and then extracting the solution extracted from the shaking incubator at 25~28 ° C. for 20~30 hours at 130~170 rpm in a centrifuge at 7,500~8,500 rpm The supernatant obtained by centrifugation for ~25 minutes is concentrated with a rotary evaporator.

More specifically, sea cucumber is added to 80% ethanol so that the mixture ratio of sea cucumber and ethanol is 1: 10 by weight. And extracted in a shaking incubator at 26 DEG C and 150 rpm for 25 hours. Centrifuge the extracted solution for 20 minutes at 8,000 rpm using a centrifuge. The supernatant is filtered through Whatman No.2 filter paper, and the filtrate is concentrated on a rotary evaporator (Rotavapor).

The amount of the natural ultraviolet screening extract to be used is limited within a range of 0.1 to 5.0 wt% with respect to the total weight of the composition. When the amount of the natural ultraviolet screening extract is less than 0.1 wt%, the ultraviolet screening effect is insignificant, Since the content of the other components is decreased, the functional properties such as thin film formation, antibacterial and antioxidation, moisturizing and the like may be deteriorated. Therefore, the amount of the natural ultraviolet screening extract is preferably limited within the above-mentioned content range.

The natural ultraviolet screening extract was prepared by mixing 10 ~ 35 wt% of red ginseng, 10 ~ 35 wt% of rhizome, 10 ~ 35 wt% of rhizome and 10 ~ 35 wt% of visa, And the mixture is mixed at a weight ratio of 1: 5 to 20, and the mixture is shaken at 20 to 30 ° C and 150 to 300 rpm for 5 to 60 hours. The resulting solution is filtered using a filter, and the filtrate is transferred to a rotary evaporator Use concentrated one.

More specifically, 25 wt% of ginseng, 25 wt% of rhizome, 25 wt% of rhubarb, and 25 wt% of viscose are mixed to form a herbal medicine mixture and then ground. The crushed herbal medicine mixture is added to 90% methanol, and the crushed herbal medicine mixture and 90% methanol are mixed at a mixing ratio of 1:10 by weight. And extracted in a shaking incubator at 26 DEG C and 200 rpm for 50 hours. The extracted solution is filtered through a filter (Whatman No.2 filter paper), and the filtrate is concentrated on a rotary evaporator (Rotavapor).

The specific formulation ratio of the coating composition for preventing tattoo site infection is shown in Table 1 below.

ingredient Example 1 Example 2 Example 3 Example 4 Example 5 Purified Water 89.0 91.0 90.0 91.0 89.0 Polyvinyl alcohol
5.8
4.2
4.0
3.0
3.0 Dimethicone
1.0
1.0
2.0
1.0
1.0 Ethylhexylglycerin
2.0
1.7
1.6
1.2
0.4 1,2-Hexanediol < / RTI >
1.5
1.0
1.5
1.0
0.5 Hydroxyethyl cellulose
0.1
0.2
0.2
0.4
0.1 Natural antioxidant and antibacterial extracts ¹⁾
0.2
0.3
0.2
0.8
2.0 Natural moisturizing extract ²⁾
0.2
0.3
0.2
0.8
2.0 Natural sunscreen extract ³⁾
0.2
0.3
0.3

0.8
2.0

In Table 1,

1) The natural antioxidant and antimicrobial extracts were extracted from a mixture of 50wt% of Sansui oil extract, 25wt% of Cheonjiyangcho extract and 25wt% of Hwasungcho extract.

2) The natural moisturizing extract is extracted from a mixture of 35 wt% of ginseng extract, 35 wt% of water extract and 30 wt% of sea cucumber extract.

3) The extract of natural sunscreen extract was extracted from a mixture of 25wt% of ginseng, 25wt% of caustic, 25wt% of rhubarb, and 25wt% of visa.

In addition to the above-described technical arrangement,

The coating composition for preventing tattoo site infection may be further added with a natural skin-soothing composition to impart a soothing effect to the skin after tattooing.

More specifically,

10-50 wt% Centella asiatica extract,

10 ~ 50 wt% of lettuce extract,

0.1 to 5.0 wt% of a 100 wt% natural skin-soothing composition (h) composed of a mixture of 10 to 50 wt% of spirulina extract.

Specific examples of the composition for natural skin cleansing (h) include those composed of a mixture of Centella asiatica extract 30 wt%, lettuce extract 40 wt%, and spirulina extract 30 wt%.

The Centella asiatica is a perennial herbaceous herbaceous plant belonging to the mountain type. It is called mulberry, red tulip, and tiger grass. It is a tasteless and odorless flour that grows well in water or water. Asiaticoside and madecasso-side, which are pentacyclic triterpene glycosides belonging to the a-amyrin-ursolic acid group as a main component of centella, have long been used for treating skin wounds and chronic ulcers. It is known to stimulate collagen production with a regenerative drug of skin tissue.

The centella asiatica extract was prepared by adding the crushed Centella asiatica to 70% ethanol and adding the Centella asiatica so that the blend ratio of the Centa asiatica and 70% ethanol was 1: 5-15 by weight, and the Centella asiatica was immersed at 23-25 ° C for 20-30 hours After the supernatant is separated from the precipitate and the same procedure is repeated 2 to 4 times, the obtained solution is filtered using a filter paper (Whatman No. 2), and the filtrate is concentrated by a rotary evaporator (Rotavapor) .

More specifically, the ground loofah was soaked in 10 times by weight of 70% ethanol and after 24 hours, the supernatant and the precipitate were separated. The same procedure is repeated three times.

The extracted solutions are combined, filtered through a filter paper (Whatman No. 2), and concentrated using a rotary evaporator (Rotavapor) to produce Centella asiatica extract.

The lettuce extract is prepared by mixing crushed lettuce and ethanol in a ratio of 1: 5 to 20 by weight, filtering the resulting solution by sonication, and concentrating the filtrate with a rotary evaporator (Rotavapor) .

More specifically, ground lettuce is added to 80% ethanol, and the mixture is added so that the mixing ratio of crushed lettuce and 80% ethanol is 1:10 by weight. Ultrasonic waves of 60 kHz are generated for 25 minutes and then extracted at room temperature for 55 hours. The extracted solution is filtered through a filter (Whatman No. 2), and the filtrate is concentrated on a rotary evaporator (Rotavapor).

Spirulina (Spirulina platensis) is one of the oldest algae on Earth, the first photosynthetic organism born about 3.5 billion years ago. Ingredients include 60-70% protein, 6-9% lipid, 15-20% carbohydrate and a large amount of vitamins, minerals and fiber.

The mixture of Spirulina and Spirulina extract at a weight ratio of 1: 40-50 was extracted at 25 to 28 ° C for 60 to 65 hours at 100 to 150 rpm in a shaking incubator, and the extracted solution was centrifuged at 7,000 to 8,000 rpm The supernatant obtained by centrifugation for 10 to 20 minutes is filtered with a filter paper (Whatman No. 2), and the filtrate is concentrated by a rotary evaporator (Rotavapor).

More specifically, the mixture of Spirulina and distilled water at a ratio of 1: 50 by weight was extracted in a shaking incubator at 130 rpm at 26 DEG C for 63 hours, and the extracted solution was centrifuged at 7,500 rpm for 15 minutes in centrifugation, The filtrate was filtered through a filter paper (Whatman No. 2), and the filtrate was concentrated with a rotary evaporator to prepare Spirulina extract.

In addition to the ingredients presented above,

Grapefruit seed extract to extend the period of preservation and use of a coating composition for preventing tattoo site infection, a chimma extract having a skin aging-preventing function, and a gold extract having a moisturizing function, thereby further enhancing the functionality.

The grapefruit seed extract is a natural antimicrobial material containing ascorbic acid, palmitic acid, glucoside, naringin, and tocopherol, and is used as a preservative in the present invention.

The grapefruit seed extract is prepared by mixing grapefruit seed with ethanol at a weight ratio of 1:10 to 20, refluxing the mixture at a temperature of 55 to 60 ° C for 3 to 5 hours, centrifuging at 10,000 × g for 20 to 40 minutes, The supernatant is filtered and the filtrate is concentrated by rotary evaporation.

The grapefruit seed extract is used within a range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection. When the amount of the grapefruit seed extract is less than 0.1 wt%, it is difficult to expect the improvement of the preservative function by grapefruit seed extract. the amount of the grapefruit seed extract to be used is preferably limited within the range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection.

It has been known for a long time that it has been used as a medicinal agent of oriental medicine, and is effective not only for stress and fatigue but also for the treatment of headache, stroke, cranial nervousness, hypertension, diabetes and the like. Chunma extract has antioxidant activity and anti-wrinkle effect of collagen degradation inhibitor.

The chewing gum extract was prepared by mixing the chewing gum and distilled water at a weight ratio of 1:10 to 20, extracting the mixture at 90 to 95 ° C for 3 to 6 hours using a reflux extractor, centrifuging the extract at 3,000 to 4,000 rpm for 3 to 10 minutes The supernatant was filtered, and the filtrate was concentrated by a rotary evaporator.

The chitin extract is used in an amount of 0.1 to 3.0 wt% based on the total weight of the anti-infective coating composition. When the amount of the chitin extract is less than 0.1 wt%, the anti- The improvement in skin aging prevention effect is insignificant because it is insignificant. Therefore, it is preferable that the amount of the chymus extract is limited within a range of 0.1 to 3.0 wt% with respect to the total weight of the coating composition for preventing infection.

The gold extract is used as a moisturizing aid to assist moisturizing function of a natural moisturizing extract constituting a coating composition for preventing infection. The mixture is prepared by mixing gold and methanol at a weight ratio of 1: 5 to 10 at a temperature of 60 to 70 ° C The extract is centrifuged at 3,000 ~ 5,00 rpm for 5 ~ 10 minutes and the supernatant is filtered. The filtrate is concentrated by rotary evaporator.

The gold extract is used in an amount of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection. When the amount of the gold extract is less than 0.1 wt%, it is difficult to improve the moisturizing function by the gold extract. The amount of the gold extract is preferably limited within a range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection.

The anti-infection coating composition prepared through the above process is filled into a container together with a liquefied gas such as dimethyl ether commonly used in conventional spray-type products, and is sprayed on the tattoo site by a spraying method to form a film thin film.

The coating composition for prevention of tattoo site infection according to the present invention can easily spray the tattoo area around the tattoo area after the tattoo operation so that the film thin film is formed at the tattoo site to prevent the bacteria from penetrating into the human body through the tattoo site, And has antioxidant and antimicrobial functions by itself to prevent skin aging and skin pollution, and has an effect of improving skin health condition by skin moisturizing and ultraviolet shielding function, which is highly likely to be industrially applicable.

Claims (7)

Water (a) 89.0 to 95.0 wt%;
Polyvinyl alcohol (b) 3.0 to 6.0 wt%;
Dimethicone (c) 1.0 to 3.0 wt%;
Ethylhexylglycerin (d) 0.1 to 2.0 wt%;
1,2-Hexanediol (e) 0.1 to 2.0 wt%;
(F) 0.1-0.5 wt% of the thickener of hydroxyethylcellulose;
The mixture was added to 20 to 50 times of distilled water and extracted with shaking at 35 to 39 ° C at 150 to 300 rpm for 1 to 48 hours. 10 to 50 wt% of the extract of corn oil, prepared by concentrating the filtrate obtained by extracting the obtained solution with a filter using a rotary evaporator,
After freeze-drying, the milled powdery starch powder was added in a ratio of 1:10 to 30 by weight with water, and the resulting solution was extracted at 28 to 32 ° C for 22 to 26 hours. The resulting solution was centrifuged at 10,000 to 13,000 The mixture was centrifuged at rpm for 15 to 30 minutes, and the supernatant was filtered with a filter. The filtrate was concentrated with a rotary evaporator (Rotavapor), and 10 to 50 wt%
A series of processes of immersing the herpes zoster with ethanol at a weight ratio of 1: 5 to 15 at a temperature of 23 to 27 ° C for 20 to 30 hours, separating the supernatant and the precipitate is repeated 2 to 4 times, and the obtained solution is centrifuged The mixture was centrifuged at 10,000 to 13,000 rpm for 15 to 30 minutes. The supernatant was filtered with a filter, and the filtrate was concentrated with a rotary evaporator to obtain 100 wt% (G) 0.1 ~ 5.0 wt% of natural antioxidant and antimicrobial extract;
The mixture of crushed bamboo shoots and ethanol was mixed at a weight ratio of 1: 5 to 20, sonicated, and the obtained solution was filtered, and the filtrate was concentrated using a rotary evaporator. 50 wt%
The mixture of water stem and leaf were mixed at the same weight ratio and then dried at 63 to 68 ° C for 6 to 10 hours so that the water content was 5 wt% or less. The dried water mixture was mixed with 80% ethanol at a weight ratio of 1: 5 to 20 And the mixture is refluxed and cooled for 2 to 4 hours in a water bath at 75 to 85 ° C for 2 to 4 times. The obtained solution is filtered, and the filtrate is concentrated by a rotary evaporator (Rotavapor) 10 to 50 wt% of the extract,
The mixture of sea cucumber and ethanol in a weight ratio of 1: 5 to 15, and the solution extracted from the shaker incubator at 25 to 28 ° C for 20 to 30 hours at 130 to 170 rpm is centrifuged at 7,500 to 8,500 rpm for 15 to 25 minutes 0.1 to 5.0 wt% of a 100 wt% natural moisturizing extract (h) composed of 10 to 50 wt% of a sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotary evaporator (Rotavapor);
And 10 to 35 wt% of rhizome and 10 to 35 wt% of rhizome were mixed and then ground, and the ground mixture was mixed with 90% methanol and 1: 5 to 20 wt% And the resulting solution is filtered using a filter. The resulting filtrate is concentrated using a rotary evaporator (Rotavapor), and the filtrate is filtered through a rotary evaporator (Rotavapor) (A + b + c + d + e + f + g + h + i) of the blocking extract (i) in an amount of 0.1 to 5.0 wt%;
The method according to claim 1,
The crushed greenhouse was added to 70% ethanol, and the mixture was mixed at a ratio of 1: 5 to 15: 1 by weight. The mixture was immersed at 23 to 25 ° C for 20 to 30 hours. The supernatant was separated from the precipitate, The same procedure was repeated 2 to 4 times. The obtained solution was filtered using a filter paper (Whatman No. 2), and Centella asiatica extract, prepared by concentrating the filtrate with a rotary evaporator (Rotavapor) 50 wt%
The mixture of crushed lettuce and ethanol was mixed at a weight ratio of 1: 5 to 20, and the resulting solution was subjected to sonication. The resulting solution was filtered, and the filtrate was concentrated using Rotavapor. 50 wt%
Spirulina and distilled water were mixed at a ratio of 1: 40-50 by weight, and the mixture was extracted at 100 to 150 rpm for 60 to 65 hours at 25 to 28 ° C in a shaking incubator. The extracted solution was centrifuged at 7,000 to 8,000 rpm for 10 to 20 minutes The filtrate was filtered through a filter paper (Whatman No. 2) obtained by centrifuging the filtrate. The filtered filtrate was concentrated with a rotary evaporator to obtain 100 wt.% Of a mixture of 10-50 wt% of Spirulina extract % Of natural skin-soothing composition (h) 0.1 to 5.0 wt%.
The method according to claim 1,
The mixture of grapefruit seed and ethanol was mixed at a weight ratio of 1:10 to 20, and the mixture was refluxed for 3 to 5 hours at a temperature of 55 to 60 ° C and centrifuged at 10,000 × g for 20 to 40 minutes. The supernatant was filtered And 0.1 to 3.0 wt% of a grapefruit seed extract (i) prepared by concentrating the concentrate with a rotary evaporator (Rotavapor).
The method according to claim 1,
The mixture of Chunma and distilled water was mixed at a weight ratio of 1:10 to 20, and the mixture was extracted at 90 to 95 ° C for 3 to 6 hours using a reflux extractor. The extract was centrifuged at 3,000 to 4,000 rpm for 3 to 10 minutes, And 0.1 to 3.0 wt% of a chewing gum extract (j) prepared by concentrating the filtered filtrate with a rotary evaporator (Rotavapor).
The method according to claim 1,
The mixture of gold and methanol in a weight ratio of 1: 5 to 10 is refluxed at 60 to 70 ° C for 10 to 20 hours, the extract is centrifuged at 3,000 to 5,00 rpm for 5 to 10 minutes, And 0.1 to 3.0 wt% of a gold extract (k) prepared by concentrating a filtrate with a rotary evaporator (Rotavapor).
Preparing a natural antioxidant and antimicrobial extract by mixing 10 to 50 wt% of a corn oil extract, 10 to 50 wt% of a perennial plant extract, and 10 to 50 wt% of a perennial plant extract,
Preparing a natural moisturizing extract by mixing 10 to 50 wt% of a ginseng extract, 10 to 50 wt% of a water extract, 10 to 50 wt% of a water extract, and 10 to 50 wt% of a sea cucumber extract,
Preparing a natural ultraviolet screening extract from a mixture of 10 to 35 wt% red ginseng, 10 to 35 wt% of rhizome, 10 to 35 wt% of rhubarb, and 10 to 35 wt% of visa,
Wherein the emulsion contains from 89.0 to 95.0 wt% of purified water, 3.0 to 6.0 wt% of polyvinyl alcohol, 1.0 to 3.0 wt% of dimethicone, 0.1 to 2.0 wt% of ethylhexyl glycerin, 0.1 to 5.0 wt% of a natural antioxidant / antibacterial extract, 0.1 to 5.0 wt% of a natural moisturizing extract, 0.1 to 5 wt% of a natural antioxidant / antimicrobial extract, 0.1 to 2.0 wt% of a 1,2-hexanediol, 0.1 to 5.0 wt% of an ultraviolet screening extract to form a mixture for a coating composition;
Stirring the mixture at 500 rpm to 1,000 rpm for 1 to 3 hours,
The method of claim 1, wherein the coating composition is prepared by mixing a mixture of the coating composition and the coating composition in a mesh of 200 to 500 mesh.
The method of claim 6,
The step of forming the mixture for the coating composition
0.1 to 5.0 wt% of a 100 wt% natural skin-soothing composition comprising 10-50 wt% of Centella asiatica extract, 10-50 wt% of lettuce extract and 10-50 wt% of spirulina extract;
The mixture of grapefruit seed and ethanol was mixed at a weight ratio of 1:10 to 20, and the mixture was refluxed for 3 to 5 hours at a temperature of 55 to 60 ° C and centrifuged at 10,000 × g for 20 to 40 minutes. The supernatant was filtered 0.1 to 3.0 wt% of grapefruit seed extract prepared by concentrating it with a rotary evaporator (Rotavapor);
The mixture of Chunma and distilled water was mixed at a weight ratio of 1:10 to 20, and the mixture was extracted at 90 to 95 ° C for 3 to 6 hours using a reflux extractor. The extract was centrifuged at 3,000 to 4,000 rpm for 3 to 10 minutes, The filtrate was concentrated with a rotary evaporator (Rotavapor) to prepare a chewy gum extract 0.1 to 3.0 wt%; or
The mixture of gold and methanol in a weight ratio of 1: 5 to 10 is refluxed at 60 to 70 ° C for 10 to 20 hours, the extract is centrifuged at 3,000 to 5,00 rpm for 5 to 10 minutes, 0.1 to 3.0 wt% of a gold extract prepared by concentrating a filtrate with a rotary evaporator (Rotavapor); Wherein the composition for the coating composition is prepared by adding one or more kinds of extracts selected from the group consisting of at least one kind selected from the group consisting of: