KR20160144549A - Acaricide and nematocide composition comprising 1-undecanol - Google Patents

Abstract

The present invention relates to a salvage and nematocide composition containing 1-undecanol as an active ingredient, and has an excellent effect of controlling harmful mites and nematodes that cause great damage to horticulture, flowers, and trees by using the above composition.

Description

1-undecanol as an active ingredient and to a composition comprising 1-undecanol as an active ingredient.

The present invention relates to a salvage and nematocide composition containing 1-undecanol as an active ingredient, and more particularly to a salvia and nematode composition having harmful mites and nematodes which are harmful to horticulture, flower and tree, To nematicide compositions.

Pests are a collective term for insects that directly or indirectly harm human life, and double mites and nematodes are typical pests that infest harmful to horticulture, flower, and tree. Typically, harmful mites such as tomatoes, strawberries, pears, apple trees, such as a very wide host range occurs more than 10 times a year, and apple trees, pomegranate apple trees and pears, 8 times a year to cause damage to apple mite, And cherry blossom cherry tree which damages cherry tree which is a broad-leaved tree. In addition, representative harmful nematodes include damage to the Chinese cabbage cultivated in the Gangwon area, such as nematodes and root-knot nematodes, which hump the root of 300 kinds of crops such as carrots, watermelons, tomatoes and peppers, Sugarcane syste, and pine tree reeds that can be tested within three months.

As the nematicide for the purpose of controlling the nematode, there is currently an antimicrobial agent such as dazometh, bifenthrin, cadusafos, postiazate, metham sodium, morranetatrate, milbemectin, abamectin, emamectin benzoate, , Bromine series, diphenyl series, organosilicate series, amitraz series, tetrazine series, hexacyadene series, synthetic pyrethroid series, pyridazinone series, ascylurea series, antibiotics, microbial agents, thiourea series, (Crop Protection Guidelines 2012. Korea Crop Protection Association).

However, these medicines have not been developed in the domestic market, and the medicines developed and manufactured outside the country are imported, and the unit price is high, and they are packed and used. Therefore, there is a need for an economic, cost effective and effective nematode formulation for domestic pest control.

1-undecanol is a fragrant fatty alcohol found in fruits such as apples and bananas. However, it is not known about the salivary and carnivorous compositions which still contain 1-undecanol as an active ingredient.

Accordingly, an object of the present invention is to provide a composition for preventing and treating harmful mites and nematodes against harmful mites and nematodes, which are harmful to horticulture, flowers and trees.

It is another object of the present invention to provide an acaricide or nematicide containing the composition.

In order to accomplish the above object, the present invention provides a method for producing a 1-undecanol composition, comprising: mixing 1-undecanol, an emulsifier and purified water to prepare a 1-undecanol composition; Diluting the composition to 250 to 1,000,000 times with purified water to prepare a diluted solution; The above diluted solution is treated with the spotted mite and the pine tree creeper to evaluate the saliva and nematode activity of the salvage and nematicide composition containing 1-undecanol as an active ingredient.

The present invention not only has an effect that 1-undecanol can be used as a composition for preventing and treating harmful mites and nematodes, but also has an excellent effect of controlling harmful mites and nematodes which cause great damage to horticulture, flowers and trees by using the composition.

FIG. 1 is a graph showing the saliva effect of the 1-undecanol composition against the spotted mite when treated with a litter-bed.
2 is a graph showing the effect of spraying on the spray treatment of the 1-undecanol composition against the spotted mite.
FIG. 3 is a graph showing the effect of the nematode on the treatment of the 1-undecanol composition on the pine wilt.
4 is a graph showing the effect of Triton X-100 on the carnivorous activity of 1-undecanol.
5 is a graph showing the effect of the emulsifier on the carnivorous activity of 1-undecanol.

The present invention relates to a process for preparing a 1-undecanol composition by mixing 1-undecanol, an emulsifier and purified water; Diluting the composition to 250 to 1,000,000 times with purified water to prepare a diluted solution; The above diluted solution is treated with the spotted mite and the pine wilt, and the step of evaluating the saliva and nematode activity of the salvage and nematicide composition containing 1-undecanol as an active ingredient is completed.

1-undecanol, which is an active ingredient, has a structure of the following formula 1 and can be used as it is without adding other ingredients, but it can be formulated into a form suitable for use according to the usual preparation method of acaricide and nematicide. That is, 1-undecanol may be formulated in appropriate proportions together with an inert carrier or adjuvant and dissolved, separated, suspended, mixed, impregnated, adsorbed or adhered to form appropriate formulations such as suspensions, emulsions, liquid preparations, wettable powders, granule wettable powders, , Tablets, packs and the like.

The inert carrier used in the present invention may be either solid or liquid. Examples of the material that can be used as a solid carrier include flour, grain powder, wood flour, bark powder, sawdust powder, tobacco stem powder, (Such as kaolin, bentonite, and acidic clay), talc (such as talc, pyrophyllite, etc.), silicas [for example, (For example, synthetic high-dispersion silicic acid, also called hydrated silicic acid or hydrated silicic acid, which contains calcium silicate as a main component depending on the product)], activated carbon, sulfur powder, pumice, calcined diatomaceous earth, brick Inorganic mineral powders such as pulverized material, fly ash, sand, calcium carbonate and calcium phosphate, plastic carriers such as polyethylene, polypropylene and polyvinylidene chloride, yuan , Compost, manure, draft, urea, urea, etc., and they can be used alone or in the form of a mixture of two or more kinds. Such as water, alcohols (e.g., methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (e.g., (Such as acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, cyclohexanone), ethers (e.g., ethyl ether, dioxane, cellosolve, dipropyl ether, tetrahydrofuran, etc.), aliphatic hydrocarbons Aromatic hydrocarbons such as benzene, toluene, xylene, solvent naphtha, alkylnaphthalene, etc., halogenated hydrocarbons such as dicyclohexylcarbodiimide, (For example, ethyl acetate, diisopropyl phthalate, dibutyl phthalate, dioctyl phthalate and the like), amides (for example, dimethylformamide, diethylformamide, dimethylacetate Amides and the like), nitriles (e.g., acetonitrile and the like), dimethylsulfoxide and the like.

Emulsifiers are used for the purpose of emulsifying, dispersing, solubilizing and / or wetting the active ingredient compound. Examples thereof include surfactants such as BFC30, HP11, CP11EA, CO25, CO10 and Triton X-100. For the purposes of dispersion stabilization, adhesion and / or binding of the active ingredient compound, the following adjuvants may be used. Examples thereof include casein, gelatin, starch, methylcellulose, carboxymethylcellulose, gum arabic, polyvinyl alcohol, Adjuvants such as sesame oil, sugar oil, bentonite, and lignin sulfonate may also be used.

In order to improve the fluidity of the solid product, the following adjuvants may be used. For example, adjuvants such as wax, stearate, and alkyl phosphate ester may be used. As the peptizing agent of the suspension product, auxiliary agents such as condensates of naphthalenesulfonic acid and condensed phosphate may be used. As the antifoaming agent, for example, auxiliary agents such as silicone oil may be used. As the preservative, 1,2-benzisothiazolin-3-one, para-chloromethacylenol, butyl p-hydroxybenzoate and the like can also be added. If necessary, additives such as a functional electrodeposition agent, a metabolic decomposition inhibitor such as piperonyl butoxide, an antioxidant such as propylene glycol, an antioxidant such as BHT (dibutylhydroxytoluene) and an ultraviolet absorber may be added.

The compounding ratio of 1-undecanol, which is an effective ingredient, can be added and deteriorated as necessary. It can be appropriately selected from the range of 0.01 to 90 parts by weight, based on 100 parts by weight of the total of the components. For example, the composition may be an emulsion, a wetting agent, 0.01 to 50% by weight is suitable. The composition of the present invention may be used in the form of being diluted or suspended in water or the like as it is to control various mites and nematodes. The amount of the antimalarial composition of the present invention to be used varies depending on various factors such as purpose, target disease, crop growth, disease occurrence tendency, weather, environmental conditions, formulation, application method, application site, However, it may be suitably selected in accordance with the purpose in the range of 0.001 g to 10 kg, preferably 0.01 g to 1 kg per 10 aries as the active ingredient compound.

Examples of the nematodes include nematodes in Meloidogyne such as Meloidogyne incognita, Meloidogyne javanica, Meloidogyne hapla and Meloidogyne arenaria, nematodes such as potato rotifer Pratylenchus fallax, Pratylenchus cffeae, Ditylelenchus destructor, Ditylelenchus dipsaci, etc., Ditylelenchus nematodes, Pratylenchus penetrans, Chrysanthemum spp., Pratylenchus fallax, ), Pratylenchus nematodes such as Pratylenchus loosi and Pratylenchus vulnus, Globodera rostochiensis, Globodera pallida, etc., and the like (Heterodera) nematodes such as nematodes, Heterodera glycines, and Heterodera shachtoii in the globodera of the potatoes, Aphelenchus avenae such as Aphelenchoides besseyi, Aphelenchoides ritzemabosi and Aphelenchoides fragarieae, Aphelenchus avenae and the like, nematodes in the Aphelenchus avenae, Rotulanchus nematodes such as nematodes in Tylenchulus and rotylenchulus reniformis such as radopholus nematodes and Tylenchulus semipenetrans in Radopholus similis and the like, And nematodes such as Bursaphelenchus xylophilus (Bursaphelenchus xylophilus) that reproduce in the trees, but the present invention is not limited thereto, and the most preferable is Bursaphelenchus xylophilus.

The mites are not limited to specific mites such as Panonychus ulmi, Tetranychus urticae, Oligonychus ununguis, and Cherry spider mite, but most preferred are Tetranychus urticae.

The use of the composition of the present invention for preventing and treating mites and nematodes can be carried out by applying a conventional method to a plant, a seed or a cultivation support for sowing, in which the occurrence of mites and nematodes is predicted. It can be used as a method of application such as seeding method, seed sterilization method, hematopoietic treatment, ground treatment, roughening treatment, soil blending, etc., and for various nematodes occurring in field farming such as fruit trees, cereals and vegetables, , Immersion treatment of seedling roots, sowing of seedlings, cultivation of seedlings, harvesting of blood and main seedling carrier, surface spraying, blending treatment, and so forth. It may also be applied to hydroponic liquids in hydroponic cultivation.

In addition, the composition of the present invention can be used in combination with other disinfectants, insecticides, acaricides, nematocides, pesticides and the like for the purpose of expanding pests and controllable pests to be controlled or reducing the dosage Depending on the place of use, it may be mixed with herbicides, plant growth regulators and fertilizers.

Other bactericides used for this purpose are, for example, sulfur, lime sulfur compounds, basic copper sulfate, ibuprofen, edifenphos, tolclofos methyl, tilam, polycarbamates, zinev, manzub, But are not limited to, thiophene, thiophenate, thiophanate, methyl thiophanate, benomyl, iminostadine acetate, iminotadine alcalate, mepronil, flutolanil, penicillin, , Caprofamide, diclofenanid, flu sulfamid, chlorothalonil, krescidium methyl, phenoxanil, hyxazole, ecchromezole, fluoroimide, proximimon, binchizolein, But are not limited to, thiadiazepine, triadimefon, bitteranol, triplumizole, ipconazole, fluconazole, propiconazole, difenoconazole, muclobutanyl, tetraconazole, hexaconazole, tebuconazole, Prochloraz, piperazoate, But are not limited to, propanazole, isoprothiolane, phenarimol, pyrimethanil, mephanipyrim, pyriphenox, fluazinam, tripolin, dichromene, azoxystrobin, thiadiazine, captain, Benzoyl-S-methyl, phthalide, tricyclazole, pyroquin

Rhodamine, quinomethionate, oxolinic acid, dithianone, casagemycin, validamycin, polyoxine, blasticidin, streptomycin and the like.

Examples of pesticides, biting agents and nematicides which are used for the same purpose include ethion, trichlorfon, metamidophos, acetic acid, dichlorobos, mebinphos, monocrotophos, malathion, dimethoate, But are not limited to, for example, formotin, mecamac, bamidothione, thiomethone, disulfotone, oxydipropos, naldehyde, methylparathion, penitrothion, cyanophos, propafos, pention, , Isophenephosphate, themephosphate, pentioate, dimethylpinphosphine, chlorphenvinphosphine, tetraclobinphosphine, isocyanate, pyraclucose, methidathion, chlorpyrifos, chlorpyrifos methyl, DPS (NK-0795), Phosphorus, Phosphorus, Phosphorus, Phosphorus, Phosphorus, Phosphorus, Phenanthophos, isoamidophos, , Moving crude phosphonium, Eto Pro force on-pentynyl, phosphonic thietane, di

Thiaminazines, sulfoproposes, penethothiones, thiamidafos, pyretrin, alretrin, fralethrin, resmethrin, permethrin, tefluthrin, bifenthrin, penproperin, cypermethrin , Alpha cypermethrin, cyhalothrin, lambda cyhalothrin, deltamethrin, acinatrin, penvalerate, espen valerate, cycloprothrin, ethopenprox,

But are not limited to, halfenprox, halafenprox, silaflophene, flucytinate, fluorvalinate, mesomil, oxamil, thiodicarb, aldicarb, allanicab, caltab, methocarb, (2-sec-butylphenyl-N-methylcarbamate), carbaryl, pyrimicarb, carbofuran, carbosulfan, furathiocarb, benzofurane, Cob, aldoxycarb, diapenturon, diplubenuron, teflubenuron, hexaflumuron, novuluron, lupenuron, flupenoxolone, chlorflualuron, oxidized penbuta tin, tricyclohexylhydroxide tin , Sodium oleate, potassium oleate, methoprene, hydroprene, binaparyl, amitraz, dicopol, kelsen, chlorbenzilate, phenisobromorate, tetradipone, benzyltop, benzomate, tebufenozide, Methoxyphenozide, pyridaryl, metafluormizone, flu But are not limited to, thioxanthines, thioxanthones, thioxanthones, thioxanthones, thioxanthones, thioxanthones, thioxanthones, thioxanthones, thioxanthones, Wherein the at least one compound is selected from the group consisting of at least one compound selected from the group consisting of at least one compound selected from the group consisting of atropine, Pyridaben, cyromazine, TPIC (tripropylisocyanurate), pimetrozine, clopentazine, bupropezin, thiosiclam, phenazakin, quinomethionate, indoxacarb, polynactin complex , Milbemectin, abamectin, emamectin benzoate, spinosad, BT (bacillus thuringiensis), azadiractin, rotenone, hydroxypropyl starch, levamisole hydrochloride, metham sodium, Jamet, trichramide, Pasteuria penetrans, Monacrosporium phymatopagum, and the like.

As herbicides, there may be mentioned, for example, glyphosate, sulphosate, glufosinate, bialaphos, butamipos, esprocar, prosulfocarb, benthiocarb, pyributicarb, asulam, , Isosuron, benzofuron methyl, cyclosulfamuron, cinosulfuron, pyrazosulfuronethyl, azimosulfuron, imazosulfuron, tenylchlor, allachlor, prtilachlor, clomeprop, etobenanide, , Pendimethalin, bifenox, acifluorfen, lactophen, cyhalopopbutyl, dioxinyl, bromobutide, alloxydim, cetoxydim, napropamide, indanopan, pyrazolate, benzo But are not limited to, phenanthrene, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, pyrazole, Furateate, flutiasetmethyl, quizalofop ethyl, Tajon, may include calcium peroxide, etc.

Throughout this specification, the '%' used to denote the concentration of a particular substance, unless stated otherwise, is defined as the weight of the solid / solid (weight / weight), the weight of the solid / liquid (weight / volume) The liquid / liquid is (vol / vol)%.

Hereinafter, the present invention will be described in more detail with reference to embodiments and drawings. However, the following examples are intended to illustrate the invention and are not intended to limit the scope of the invention.

Example 1. Preparation of 1-undecanol composition

1-undecanol as an active ingredient, 1-undecanol composition for nematode and acaricide was prepared as a nematode and acaricide as shown in Table 1 below. The 1-undecanol was purchased from Sigma-Aldrich.

1-undecanol composition division matter Mixing Ratio (mL) 1-undecanol
Final concentration Active ingredient 1-undecanol One
1000ppm

Emulsifier 0.1% BFC30 One Purified water Pure water 998 system 1000

Example 2. Preparation of pest for 1-undecanol nematode and saliva activity test

 1-undecanol was selected as a candidate for nematode and saliva activity test for the mite and saliva activity test.

The spotted mite used for the inactivation test was a bark which was grown at 27 ° C on the basis of kidney bean.

The pine reeves used in the test for the viability of the above-mentioned insecticides were collected from a pine needle-pricked pine wilt of the pearl, and detected by the Baermann funnel method, and were fed to Botrytis cinerea at a temperature of 25 It was used by propagation under the constant temperature of ± 1 ℃.

Experimental Example 1 Activity test of 1-undecanol

1) Effect of 1-undecanol composition on the foliar treatment

The 1-undecanol composition prepared in Example 1 was diluted with purified water to 250X, 500X, 1000X and 2000X in order to confirm the effect of salting on the treatment of the lye of 1-undecanol composition. A 1.5 cm diameter kidney bean disc was immersed in the diluted solution prepared in the above step for 5 seconds, and then 50 dogs per disc were inoculated with the water of the surface of the kidney bean in the air. The control group, untreated group, was immersed in distilled water. In order to prevent the drying of the water in the Kangnam - kon disc, a Breeding dish (Ø10 ㎝) cotton wool was put and filled with saturated water with distilled water. The presence or absence of lethality was assessed under the anatomical microscope by using a small brush and the presence or absence of leg movement was repeated 5 times for each treatment.

As shown in FIG. 1, the mortality of the 1-undecanol composition was as low as 99.2% in 250X diluted solution but less than 29.9% in 500X, 1000X and 2000X diluted solution.

2) Effect of 1-undecanol composition on spraying

The 1-undecanol composition prepared in Example 1 was diluted with purified water to 250X, 500X, 1000X and 2000X in order to confirm the effect of spraying on the spraying of 1-undecanol composition. 50 ml of spotted mite adults were inoculated on a 1.5 cm diameter Ganoderma lucidum disk, and 1 ml of the diluted solution prepared in the above step was sprayed on a Gangnamnok disk by Potter Spray method and placed in a 25 ° C thermostat for 24 hours. Control group, untreated group, sprayed 1 ml of distilled water. In order to prevent the drying of water in the Kangnam-Kon disc, Breeding dish (Ø10 cm) cotton wool was put and filled with saturated water with distilled water. The presence or absence of lethality was assessed under the anatomical microscope by using a small brush and the presence or absence of leg movement was repeated 5 times for each treatment.

As shown in FIG. 2, the spraying effect of 1-undecanol composition was 79%, 43.6%, 35.4% and 31.8% in 250X, 500X, 1000X and 2000X diluted solutions, respectively.

Experimental Example 2 1-undecanol was tested for carnivorous activity

1) Effect of 1-undecanol composition on the nematode effect

1-undecanol composition, the 1-undecanol composition prepared in Example 1 was diluted with purified water to 10 ³ X, 10 ⁴ X, 10 ⁵ X, and 10 ⁶ X, And the mortality rate of pine tree rewind was checked 24 hours after inoculation.

As shown in FIG. 3, the 1-undecanol composition showed a high mortality rate of 81.9% even at a concentration of 10 ⁵ X dilution of the composition.

Experimental Example 3. Effect of Emulsifier on the Nematode Activity of 1-undecanol

To investigate the effect of emulsifier on the nematode activity of 1-undecanol, a composition for the nematode of different types of emulsifier was prepared as shown in Table 2 below.

division matter Mixing Ratio (mL) Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Active ingredient 1-undecanol One One One One One One

Emulsifier


0.1% BFC30 One - - - - - 0.5% Triton X-100 - One - - - - 0.1% HP11 - - One - - - 0.1% CP16EA - - - One - - 0.1% CO25 - - - - One - 0.1% CO10 - - - - - One Purified water Pure water 998 998 998 998 998 998 system 1000 1000 1000 1000 1000 1000

1) Effect of Triton X-100 on the nematode activity of 1-undecanol

In order to examine the effect of Triton X-100 on the carnivorous activity of 1-undecanol, the carnivorous activity of the composition of Comparative Example 1 was confirmed.

Triton X-100 is the most commonly used emulsifier in the manufacture of nematicide.

COMPARATIVE EXAMPLE 1 The composition was diluted to 1000X, 2000X, 4000X, 8000X and 10000X in purified water, and the pine reeves were inoculated into the diluted solution. After 24 hours, the mortality of the pine reeves was confirmed. As shown in FIG. 4, when the composition of Comparative Example 1 in which Triton X-100 was used as an emulsifier was treated with a pine reeves, 100% carnivorous activity was exhibited at 1,000X and 2,000X diluted solutions of the composition. However, the composition showed a very low nematicidal activity of 40% or less in the 4,000 × diluted solution. Compared with the carnivorous activity of Experimental Example 2, the carnivorous activity of the composition of Comparative Example 1 was lower.

2) Effect of emulsifier on the nematode activity of 1-undecanol

In order to confirm the effect of the emulsifier on the nematode activity of 1-undecanol, the compositions of Example 1 and Comparative Examples 2 to 5, in which five kinds of emulsifiers such as HP11 were prepared as shown in Table 2, were added to purified water at 1000X, 10,000X, 100,000X and 1000,000X, and these dilutions were inoculated into pine reeves to determine the mortality of pine rewind after 24 hours.

As shown in Fig. 5, in all of the 10,000X diluted solution-treated groups of the five types of emulsifiers such as HP11, more than 80% of nematicide activity was exhibited. These results show that the composition using the Triton X-100 of Example 1, Example 1, as an emulsifier shows a very high level of live nematode activity.

INDUSTRIAL APPLICABILITY The present invention is not only a novel salicylic and nematicide composition comprising 1-undecanol as an active ingredient, but also effectively inhibits harmful mites and nematodes that cause harmful effects on horticulture, flower and tree, .

Claims (6)

1-undecanol as an active ingredient and having an activity of alleviating and nematode. The composition according to claim 1, wherein the composition is characterized by a spore mite and a spore nematode activity against pineworms, pine reeves The composition according to any one of claims 1 to 3, characterized in that an emulsifier is further added to the composition The composition according to claim 3, wherein the emulsifier is selected from BFC30, HP11, CP16EA, CO25, CO10 A composition comprising the composition of any one of claims 1 to 4 as an active ingredient, A nematicide containing a composition according to any one of claims 1 to 4 as an active ingredient

Images