KR20160043698A - Composition for treating hair or scalp to prevent hair loss - Google Patents

Abstract

The present invention relates to a composition for preventing hair loss and treating scalp problems. More specifically, the present invention relates to a composition which is effective in preventing hair loss, promoting hair growth, and treating scalp problems through composite effects of a fermented extract of a walnut epicarp and a herb medicine extract containing apricot stone, Houttuynia cordata, Perilla frutescens Britton var. acuta Kudo, dried roots of Rumex crispus L., Pleuropterus multiflorus TURCZ., Biota orientalis L. leaves, and walnut.

Description

TECHNICAL FIELD The present invention relates to a composition for preventing hair loss and for treating a scalp disease.

The present invention relates to a composition for preventing hair loss and for treating scalp disease, and more particularly, to a composition for preventing hair loss and preventing hair loss by combining the herbal medicine extracts containing apricot seeds, horseradish, chrysanthemum, , Hair growth stimulation and treatment of scalp diseases.

Hair is affected by various factors such as age, season, race, physiological factors, stress, and disease, and usually has about 50 to 100 normal 'degenerative hair loss' in a day. Usually hair growth is about 2 ~ 6 years, and the growth continues at this time, the growth rate is about 4 ~ 6mm per month. The growth rate is the fastest when it is hot and the slowest when it is cold. And hair loss occurs more in spring, autumn and winter than summer. Hair growth is usually the most active between the ages of 15 and 30 years, gradually progressing from 40 to 50 years. When age is over 50, natural hair loss due to aging begins to occur and hair loss is accelerated after age 70.

The types, cause and treatment of hair loss are as follows.

It is usually subjective and ideological to look for cases of normal hair loss symptoms. Of course, there are obvious hair loss symptoms and lesions, but there are no obvious lesions, objectively count hair loss hair number, do not observe the shape of hair, and often complain symptoms. In other words, when you look at the symptoms of "the number of hairs decreased," you may notice that the hair is thin or easily broken or broken. In many cases, there is no change in the number of hairs. Therefore, when you have alopecia ages, it is important to accurately assess your current hair condition and to understand your physical and mental health status as a whole.

Types of hair loss include alopecia areata, resting alopecia, and alopecia areata as follows.

Alopecia areata usually occurs on the scalp suddenly with one to two hairy loosening. In addition to scalp, beard, eyebrows and conspiracy can also be seen, and in severe cases hair loss can occur in the whole body. Although the exact cause is not known yet, it is thought that it is caused by autoimmune mechanism and genetic and psychological (especially stress) postpartum affects it. It may be cured naturally, but it is better to treat if the symptoms last longer than 3 months or progress more. The most common treatment modality is injection of corticosteroids and induction of immune response.

Alopecia are caused by hair loss of about 50 to 100 dormant hairs per day in normal adults. This is when hair loss occurs above normal hair loss. The causes are as follows. First, there are anticoagulants, antidepressants, antihypertensives, gastric ulcers, antiarthritics, anticonvulsants, vitamin A induction system (acne remedy) and contraceptives. If you have problems with hair loss during use of the medicine, you should use another formulation with the same effect. Secondly, excessive diet can lead to hair loss if there is anemia due to lack of protein or iron deficiency. The third is stress or fever, severe infectious disease, chronic disease, major surgery, etc. In these cases, hair loss may occur within about 3 months of the cause. Fourth, hyperthyroidism or hypothyroidism may cause hair loss in these cases. In most cases, hair growth is restored after about 6 months if the stimulus is removed.

Alopecia in growing stage is a condition in which hair follicles are acutely severely damaged and 80 ~ 90% of hair is rapidly disappeared. Many cases are caused by chemotherapeutic agents and X-ray irradiation used in the treatment of malignant tumors. In this case, if the administration of the causative agent is stopped, the hair follicle is recovered within a few weeks, so that the hair follicle is regenerated, but the regenerated hair is thin and the growth is deteriorated.

Human hair consists of a protein called 'keratin', which is a protein that makes up nails and claws. Our visible hair consists of three layers of tissue formed in a 'follicle' shaped like a bag about 4mm below the skin. The top layer is thin, hard, scaly protective layer that is not colored. The middle layer is the thickest, hair-supporting structure, which determines the color of hair or hair and hair color. The first inner layer is a layer composed of living cells that nourishes hair growth.

The growth of hair follicles is affected by dihydrotestosterone (DHT), a derivative of the male hormone.

Testosterone, one of the male hormones, is converted to DHT by the action of a 5-reductase single enzyme, and since this is known to promote hair loss, DHT is inhibited by products that prevent hair loss Is being developed. For example, there has been developed a treatment for male hair loss using finasteride, which has been used as a treatment for male prostate, but there are side effects such as sexual dysfunction and hepatic dysfunction, and the cause of hair loss in recent years is hair loss caused by genetic factors Since the ratio is decreased and the ratio of hair loss to various acquired factors is increasing, it is difficult to expect the hair loss treatment to be effective by the inhibition of 5-reductase single enzyme.

Korean Patent Laid-Open Publication No. 2013-0139466 discloses a composition for preventing alopecia of skin and scalp, which is composed of extracts of Liliaceae, Rhodiola, Rhizoma, Ginseng, Peony, Peony, Yeast, No. 1,373,636 discloses a composition for improving skin and scalp condition which is obtained by mixing and extracting oat, rape, sorghum, loofah, pine needles, seaweed, soybean, sancho and bamboo sap. However, In addition, there is a need to continuously study hair loss prevention.

Korean Patent Publication No. 2013-0139466 (published on December 23, 2013) Korean Registered Patent No. 1,373,636 (registered on March 6, 2014)

The present invention has been completed in order to solve the above problems, and it is an object of the present invention to provide a composition having an effect of preventing hair loss, promoting hair growth, and improving scalp disease.

Another object of the present invention is to provide a composition for preventing hair loss and treating scalp disease which is harmless to human body and does not contain a chemical component.

In order to attain the above object, the present invention is characterized by comprising a herbal medicine extract containing apricot seeds, acerbaceous mushroom, chrysanthemum root, mushroom, mushroom, mulberry leaf and walnut, and a fermentation liquid of walnut scutellum extract.

The composition of the present invention may contain 1 to 50 parts by weight of a fermentation liquid of a walnut s Curculus extract, preferably 100 to 50 parts by weight of an herbal medicine extract, based on 100 parts by weight of an herbal medicine extract. 20 to 50 parts by weight of a carrot, 1 to 30 parts by weight of a carrot, 30 to 50 parts by weight of a carrot, 50 to 80 parts by weight of a lateral leaf, and 1 to 20 parts by weight of a walnut.

The herbal medicine extract may further comprise 30 to 50 parts by weight per 100 parts by weight of apricot seeds.

In addition, the herbal medicine extract may further comprise 70 to 100 parts by weight of persimmon leaves based on 100 parts by weight of apricot seeds.

According to the present invention, the composition does not contain a chemical component and thus has less side effects, and is excellent in reducing hair loss and improving symptoms of scalp diseases such as seborrheic dermatitis.

In addition, there is less tackiness and smell, and the user's sense of rejection can be minimized.

Hereinafter, the present invention will be described in detail. Prior to this, terms and words used in the present specification and claims should not be construed as limited to ordinary or dictionary terms, and the inventor should appropriately interpret the concepts of the terms appropriately It should be interpreted in accordance with the meaning and concept consistent with the technical idea of the present invention based on the principle that it can be defined. Therefore, the constitutions described in the embodiments described herein are merely the most preferred embodiments of the present invention, and are not intended to represent all of the technical ideas of the present invention. Therefore, various equivalents which can be substituted at the time of application It should be understood that variations can be made.

The composition for preventing hair loss and scalp disease according to the present invention includes herbal medicine extracts including apricot seeds, herbal jujube, chrysanthemum, liquor, mint, hyssop, and walnut and a fermentation liquid of walnut suture extract.

The apricot seeds are seeds of apricot tree fruit. The apricot tree is a deciduous arboreous tree cultivated in fruit trees in various places. It grows about 5m in length, leaves are alternate, oval or light elliptical. The bottom of the leaf is round, the tip is sharp and sharp, the edge is sharp, the flower is pink, the flower is bloomed in April, the petal is round, the stamen is big and the pistil is one. The fruit of apricot is spherical nucleus, and there is chorion, and it ripens in yellow in June. Apricot is also known as a passerine, and it contains unsaturated fatty acids and various skin-friendly ingredients, which are effective in preventing dullness and freckles. Especially, the extract oil of apricot seeds has been used for skin whitening since ancient times, and has antibacterial anti-inflammatory function, which is also effective for oily skin.

The above-mentioned Soseongcho refers to the upper part of the flowering period of the Hamaetong (Houttuynia cordata Thunberg). It grows in the southern part of Korea, Jeju Island, and Ulleungdo. It is a herb that has a red stalk, leaves resemble sweet potato leaves, and taste is a little spicy. The underground stalk is long, narrow, thin and white. The stem is straight and 20 ~ 50cm high, with several vertical lines, no hair, and smell. Leaves are alternate phyllotaxis, wide ovate heart shape, 3 ~ 8cm long, pointed end, plain edge, stipule attached to bottom of petiole. The flower blooms in May to June, and the end of the stem of the stem ends up with a number of spikes on the end of the stem. The involucre is divided into 4 pieces and ran in a cross shape under the inflorescence and look like petal. The cracked pieces are elliptical or elliptical with a length of 1.5 to 2 cm and white. The length of the inflorescences is 1 ~ 3cm, and there are no petals and calyxes, 3 stamens and 1 pistil. There are three styles. Ovaries are upper (upper) and 3 rooms. The fruit is capsule. Seeds are light brown. It is called 魚 腥 草 in the sense that it smells like fish in the stems and leaves, and it is also called intensive, herbal medicine, and collective, and has a strong antimicrobial and detoxifying action. In Japan, the same plant is called 약 薬 (十 药). In China, the same plants are used, but they are called outposts or overheads. There is an ingredient that strengthens and strengthens the capillary blood vessels because of the calcium and the minerals. It has an excellent effect on the skin diseases, and the ecstasy is especially effective for atopic skin, drug addiction and pesticide poisoning.

The above machine is an annual plant of Lamiaceae. In one room, the leaves are called "葉葉" and the seeds are called "蘇 子". They are used as perspiration, cold water, dryness, diuretic, soothing and analgesic. Sugar made from perylaldehyde contained in the pot is about 2,000 times stronger than normal sugar, so it is used for tobacco, potatoes, toothpaste and so on. It is said that the leaves are not purple, but green, and they are called for for viridis. The cleaned leaves are white flowers and smell is stronger than the carpets and they are used as medicinal materials.

The above-mentioned yupee is also known as Soru-zui, and other names include mollusk, shoguji, and yotei. It is called 黄 黄 (黄 黄), 菜 (枯 菜), and 牛 근 根 (牛 舌根). Young leaves may be eaten as herbs, and rootstock may be used as a medicinal product because it contains anthraquinon derivatives chrysophanol and emodin. In addition, it is effective for ringworm, athlete's foot, eczema, etc. It has been used for dermatological diseases such as improvement, omnis, skin cancer, etc. in the civilian society from the past. In the fall, the roots are curled, rounded, dried in the sun, and used as a substitute for medicine called rhubarb.

The Hassuo is a perennial vine of Chinese origin and is native to the wilderness of Korea. Its major components are anthraquinoids such as clizopanol, emodine, lane, cision, crysopanol and anthrone. In addition, it contains a large number of starches, fats and lecithin, and exists in two forms of emodin and cysteine free form and apical form, and 2,3,4,5'-tetrahydroxystilbene- beta -D-glucoside, and the like.

The hyphae are the leaves of a periwinkle tree, and the periwinkle (Thujaorientalis) is an evergreen tree belonging to the Cupressaceae. The leaves and branches of the periwinkle are sun-dried, and the perilla leaf has been used as a moisturizing agent, a hemostatic agent, or in the treatment of large intestine. It contains juniperic acid, thujone, mayurone, sabinic acid, saponin, alkaloids and vitamins, and it has a function of bleeding and haemorrhaging. .

On the other hand, walnut is a fruit of walnut tree ( Juglans sinensis ), which is a deciduous tree of the pine tree. Surgical blood is green in meat quality, and the intracranial part is not broken by very hard bone. The nucleus is obovate, yellowish brown, the surface has many wrinkles along the bongline, and there are four inside the nucleus. Seed is composed of two cotyledons, close to spherical shape, very wrinkled, white or pale yellow, and its outer surface is membranous dark brown seed coat. Generally, the nuclei in the nucleus of the walnut fruit are used for edible purposes. In the present invention, the walnut contained in the herbal medicine extract is obtained by extracting an edible nucleus portion in the endosperm as a raw material.

Herbal extracts which contain the composition of the present invention includes the seed apricot, Houttuynia cordata, perilla, Yang - di, sewage, extract of cheukbaekyeop and nut in one component, the extract is water, C hydrocarbon of _{1 ~ C 10, C 1 ~} C can be obtained by extraction using a solvent selected from ketones _10, C ₁ ~ alcohols of C ₁₀ ethers, C ₁ ~ C ₁₀ ester, C ₁ ~ C ₁₀ halogenated hydrocarbons, and C ₁ ~ C ₁₀ of the have. At this time, it is possible to use a mixed extract obtained by mixing all of the apricot seeds, acorns, mackerel, liquor, mint, horseradish, cotyledon, and walnut raw materials, or an extract separately extracted may be used. The extraction solvent may be 2 to 10 times the dry weight of the raw material, and the extraction method may be an extraction method such as hot water extraction, reflux cooling extraction, ultrasonic extraction, and the like, preferably 1 to 5 times Can be extracted.

In addition, the composition for preventing hair loss and treating scalp disease of the present invention comprises a fermentation liquid of a walnut suture extract. Since the walnut scutellum extract has a problem of being on hand, it is required to be contained in the composition of the present invention as a fermented fermentation broth.

The fermentation broth of the walnut scutellum extract may be prepared by fermenting an extract of a scutellum present in the outermost walnut fruit and then fermenting the extract. The microorganism may be prepared by fermenting the extract in a general manner such as Saccharomyces, Aspergillus, Lactobacillus, Can be used for fermentation. The fermentation can be carried out at 25 to 50 ° C for about 24 to 120 hours, preferably 48 to 72 hours, but can be appropriately controlled depending on the microorganism used and the condition of the raw materials used.

The composition for treating hair loss and scalp disease according to the present invention preferably contains 1 to 50 parts by weight, more preferably 5 to 30 parts by weight, of the fermentation liquid of walnut scutellum extract, based on 100 parts by weight of the herbal medicine extract, By weight to 20 parts by weight. When the fermented broccoli extract of walnut skins is used in an amount less than the above range, it is difficult to greatly improve the effect of preventing the hair loss by the fermentation broth, and when used in excess of the above range, the content of the herbal medicine extract, As a result, the effect of preventing hair loss is reduced.

In addition, the herbal medicine extract may contain 10 to 50 parts by weight of the perennial herb, 20 to 50 parts by weight of the herbal composition, 1 to 30 parts by weight of the herbal composition, 30 to 50 parts by weight of the herbal composition, 50 to 80 parts by weight of the hyphae, And 20 to 40 parts by weight of a pitcher, 30 to 40 parts by weight of a pitcher, 5 to 20 parts by weight of a pitcher, 35 to 45 parts by weight of a pine needle, 60 to 70 parts by weight of a pine needle, To 10 parts by weight. When each ingredient in the herbal medicine extract is included in the above-mentioned limited range, it can exhibit the effect of preventing hair loss and treating scalp disease by acting in a balanced manner among the respective active ingredients.

On the other hand, the herbal medicine extract may further include Hansik suk.

It is a perennial plant which grows in the wetlands of rice fields and streams in the central and southern parts of Korea. It contains saponin and tannin, gumminess, echulipine (vitamins A), vitamin A, nicotine and coumarin compounds. Cutting the stem of Hanwikcho leaves the juice, and after a while, it becomes oxidized and becomes black color. This is because wedelolactin is oxidized by air oxidation and has been used as a dye for jade, hair, and hair. The amount of the saccharin powder may be 30 to 50 parts by weight, preferably 35 to 45 parts by weight, based on 100 parts by weight of the apricot seeds.

In addition, the herbal medicine extract may further include persimmon leaves.

The persimmon leaf is a leaf of Persimmon ( Diospyros Kaki L. ). The persimmon is about 6 ~ 14 m in height, and the crust of the stem is split into a scaly shape, and brown branches are small branches. The persimmon leaves are slanting, leather-like, oval egg-shaped, about 7 ~ 17cm long, about 4 ~ 10cm wide, no sawtooth, petiole is 5 ~ 15mm long and hairy. The back of persimmon leaves is green and glossy. The persimmon leaves are effective against adult diseases such as hypertension, arteriosclerosis and heart disease, chronic diseases such as gastric ulcer, duodenal ulcer and diabetes, and vitamin A, C, D and chlorophyll which are known to have cancer prevention effect. In addition, it contains vitamin B1, pantothenic acid, folic acid, and tannin in a large amount. Tannin, which is a sweet taste component, has various biological activities and is known to detoxify toxins, immune function, and free radical scavenging activity. The persimmon leaves may contain 70 to 100 parts by weight, preferably 80 to 90 parts by weight, based on 100 parts by weight of apricot.

The composition for preventing hair loss and scalp disease according to the present invention may be prepared in various forms, and may be manufactured into cosmetic formulations of general emulsification and solubilization formulations. Cosmetics of emulsified form include nutrition lotion, cream, essence, etc., and cosmetics of solubilized form have softening longevity. In addition, the composition of the present invention can be prepared in the form of an adjuvant which can be applied topically or systemically, which is conventionally used in the field of dermatology by containing a dermatologically acceptable medium or base in addition to cosmetics. Suitable cosmetic formulations include, for example, solutions, gels, solid or kneaded anhydrous products, emulsions obtained by dispersing the oil phase in water, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) In the form of a dispersing agent, cream, skin, lotion, powder, ointment, spray or conceal stick. It can also be prepared in the form of a foam or in the form of an aerosol composition further containing a compressed propellant.

The composition of the present invention can further comprise at least one of a fatty substance, an organic solvent, a solubilizing agent, a thickening agent and a gelling agent, a softening agent, an antioxidant, a suspending agent, a stabilizer, a foaming agent, a perfume, a surfactant, Any other ingredients commonly used in cosmetics, such as nonionic emulsifiers, fillers, sequestering and chelating agents, preservatives, vitamins, blockers, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, , ≪ / RTI > and the like.

Examples of the product to which the composition of the present invention can be added include skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nutrition lotion, massage cream, nutritional cream, Nourishing essence, pack, soap, shampoo, cleansing foam, cleansing lotion, cleansing cream, body lotion, body cleanser, latex, press powder, loose powder and the like.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are only for describing the present invention in more detail and that the scope of the present invention is not limited by these embodiments in accordance with the gist of the present invention .

Example 1: Preparation of anti-depilation composition

The extraction solvent was added to the raw materials of 100 g of apricot seeds, 30 g of rapeseed meal, 35 g of chrysanthemum root, and 15 g of raw material, and the mixture was pulverized at 2,000 rpm for 3 minutes using a mixer. As the extraction solvent, an aqueous solution of 60 wt% ethanol was used. 600 ml of the above-mentioned extraction solvent was added and the raw material was pulverized and stirred for 3 days to obtain a first extract.

The primary extract was allowed to stand to separate the raw material of the lower part, 400 ml of the extraction solvent was further added thereto, and the mixture was stirred for 3 days to obtain a secondary extract. The raw material was separated and removed with a filter (strainer) obtained through the secondary extraction mixture, and the secondary extract from which the raw material was removed was mixed with the primary extract to obtain a herbal composition.

On the other hand, 20 g of walnut suture was pulverized for 3 minutes at 2,000 rpm using a mixer while adding an extraction solvent. As the extraction solvent, an aqueous solution of 60 wt% ethanol was used. 60 ml of the above-mentioned extraction solvent was added, and the raw material was pulverized and stirred for 3 days to obtain a primary extract. The primary extract was allowed to stand to separate the raw material of the lower layer, and 60 ml of the extraction solvent was further added thereto, followed by stirring for 3 days to obtain a secondary extract. The secondary extract mixture was separated and removed with a coarse filter (strainer), and the secondary extract from which the raw material was removed was mixed with the primary extract to obtain a walnut suture extract.

The walnut suture extract was heated at 120 ° C for 20 minutes to remove the germs. Lactobacillus fermentum was inoculated and fermented at 40 ° C for 48 hours. The microorganisms were removed by microfiltration to obtain a fermented walnut suture extract.

100 g of the crude herbal composition and 20 g of the fermentation liquid of the walnut scutellum extract were quantified and mixed to prepare a final hair loss preventing composition.

Example 2: Preparation of anti-depilator composition containing hanchonicum

In preparing the herbal medicine mixed composition, an anti-hair-loss composition was prepared in the same manner as in Example 1, except that 40 g of Hansikucho was further added.

Example 3: Preparation of anti-depilation composition containing persimmon leaves

In preparing the herbal medicine composition, an anti-depressant composition was prepared in the same manner as in Example 1 except that 80 g of persimmon leaves were further added.

EXPERIMENTAL EXAMPLE 1: Test for confirming hair loss prevention effect

The dropouts were collected with a collecting tool to measure the yield, and observed the change of dropouts. The drop-out simulation method is to measure the number of dropped mocks once a day by using a water-rinsing water and a water-rinsing tool, which is 30 cm in diameter and 20 cm in height, Respectively.

The subjects were 2 persons in the control group and 6 persons in the test group, each of 3 men and 3 women.

Here, in the test group, the compositions of Examples 1 to 3 were sprayed uniformly onto the scalp in an amount of 5 ml each time, and the number of times of daily application was twice in the morning and in the evening. For the first three days, distilled water was applied to the scalp to set the dropout threshold before use, and the extract was applied from the fourth day.

The control group applied distilled water twice a day instead of the extract.

The number of days of application of the composition was 60 days, and decidua was measured in units of 10 days.

Table 1 shows the average values of the dropout coefficients when the compositions of Examples 1 to 3 were applied.

Control group Example 1 Example 2 Example 3 Before using extract 42 44 43 41 After 10 days 41 39 37 38 After 20 days 41 35 32 35 After 30 days 45 28 26 28 After 40 days 44 24 23 25 After 50 days 42 23 23 23 60 days later 42 20 21 21

As shown in Table 1, when the composition for preventing alopecia is used, it was confirmed that the decolorization was significantly reduced as compared with the control group.

Experimental Example 2: Evaluation of scalp stability

For the experiment, 30 healthy adult men and women were selected and sprayed uniformly on the scalp by spraying 5 ml of each of the compositions of Examples 1 to 3, each 10 times per day, and the daily application frequency was continuously used for 4 weeks for 2 times in the morning and evening The skin adverse reaction (emotional reaction and external response) by the sample was confirmed and observed by the interview with the dermatologist and the scalp condition check, and the scalp fitness of the composition was judged.

The dermatologist examined the test site visually and evaluated the safety of the composition by examining the time, frequency, intensity, duration, etc. of the stimuli reported by the subject. The results are shown in Table 2.

Experiment Item Example 1 Example 2 Example 3 Scalp stability good 10 (100%) 10 (100%) 10 (100%) Poor - - -

Two of the 30 subjects who completed the experiment normally reported weak weeniness and weak papules on the scalp after using the composition. The symptoms were not severe and did not recur in subsequent use of the compositions, so the association with the composition was determined as "Unlikely Related. &Quot;

The dermatologist 's safety observation revealed that the response was not a stimulus at the level that affected the scalp safety. Thus, the scalp safety rating of the composition was judged as "good ".

Experimental Example 3: Experiment to confirm dandruff improvement effect

Thirty patients with dandruff between the ages of 10 and 70 years who did not use other products such as steroids or antibiotics from 2 weeks before the start of the experiment to the end of the experiment were studied. All subjects were sprayed uniformly on the scalp with 5 ml of the compositions of Examples 1 to 3, each 10 times per day, on the scalp having a problem for 2 weeks, and the number of times of daily application was 2 times in the morning and evening, The qualitative evaluation was made through the evaluation table as shown in Table 3.

Experiment Item Rating
Dandruff improvement effect a. Not much improved b. Not improved c. is average d. great e. Be very good

Table 4 shows the evaluation results of the subjects for the dandruff improvement effect shown in Table 3 above. The improvement effect of dandruff is that whether the dandruff symptom is alleviated within 3 days after application to the affected area, whether the dandruff reduction effect is maintained for at least 4 days, and whether the dandruff generation can be detected further for 5 days after 15 days of continuous use As a reference.

Experiment Item Rating Evaluation results Example 1 Example 2 Example 3 Dandruff improvement effect a. Not much improved - - - b. Not improved - 1 (10%) - c. is average - 1 (10%) 2 (20%) d. great 3 people (30%) 2 (20%) 3 people (30%) e. Be very good 7 (70%) 6 people (60%) 5 people (50%)

As shown in Table 4, 18 patients (60%) were present in a total of 30 patients evaluated as excellent when using the composition for preventing alopecia compared to Examples 1 to 3, and evaluated as excellent Of the 30 patients, 8 (27%) were present. Thus, the composition according to the present invention has been found to have a significant effect on dandruff improvement.

Experimental Example 4: Experiment for confirming relaxation effect of spherical oscillation

Pseudo-rash is a representative symptom observed in patients with seborrheic dermatitis. The subject was a person with acute rash among the symptoms of seborrheic dermatitis, 2 in the control group and 6 in the test group.

Here, in the test group, the compositions of Examples 1 to 3 were sprayed evenly onto the scalp 5ml each time, and the number of times of daily application was 2 times in the morning and evening.

The control group applied distilled water twice a day instead of the extract.

The number of days of application of the composition was 60 days, and peak oscillation was observed every 20 days.

Table 5 below shows the confirmed peak oscillations when the compositions of Examples 1 to 3 were applied.

Control group Example 1 Example 2 Example 3 Before using extract 10 10 10 10 After 20 days 9 4 3 3 After 40 days 10 2 One One 60 days later 11 One One One

As shown in Table 5, in the control group, the pustular rash was hardly mitigated, but in the dermatitis patients using the compositions of Examples 1 and 3, the pustular rash developed on the scalp was relaxed before the extract was used, Was remarkably decreased from the early stage when the composition was used on the 20th day, and it was confirmed that the composition was steadily relaxed until 60 days. Therefore, it was confirmed that the composition of the present invention has a function of eliminating excessive production of sebum, bad discharge of sebum, and propagation of harmful microorganisms, which is a cause of acne rash.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims. . Accordingly, the true scope of the present invention is to be determined by the following claims.

Claims (5)

Herbal medicine extracts including apricot seeds, herringbone, chrysanthemum,
A composition for preventing hair loss and treating a scalp disease, which comprises a fermentation liquid of a walnut surgical sphincter extract.
The method according to claim 1,
Wherein the composition comprises 1 to 50 parts by weight of a fermentation liquid of a walnut slice extract according to 100 parts by weight of herbal medicine extract.
3. The method according to claim 1 or 2,
Wherein the herbal medicine extract comprises 10 to 50 parts by weight of a herringbone, 20 to 50 parts by weight of a herbal composition, 1 to 30 parts by weight of a herbal composition, 30 to 50 parts by weight of a hypocotyl, 50 to 80 parts by weight of a lateral leaf, By weight of a composition for preventing hair loss and treating scalp disease.
The method of claim 3,
Wherein the herbal medicine extract further comprises 30 to 50 parts by weight per 100 parts by weight of apricot seeds.
The method of claim 3,
Wherein the herbal medicine extract further comprises 70 to 100 parts by weight of persimmon leaves per 100 parts by weight of apricot seeds.