KR102410642B1 - Hypoallergenic composition for perming eyelashes - Google Patents

Abstract

The present invention relates to a composition for eyelash perm capable of providing fixed curl to eyelashes while at the same time supplying nutrition to eyelashes, and a method of performing eyelash perm using the same.
The composition for eyelash perm of the present invention contains various eco-friendly ingredients, so that it is possible to safely perm the eyelashes without skin irritation or damage to the eyelashes, and has the advantage of being very convenient to use due to its high viscosity.

Description

Composition for perming eyelashes of hypoallergenicity {Hypoallergenic composition for perming eyelashes}

The present invention relates to a composition for eyelash perm capable of providing fixed curl to eyelashes and at the same time supplying nutrition to eyelashes, and a method of performing eyelash perm using the same.

Humans live and form relationships with many other people. In interpersonal relationships, appearance can be the subject of other people's attention or evaluation. Appearance management is an important factor in forming a first impression, and it has begun to emerge as an advantage to express one's beauty and increase competitiveness. It is not an exaggeration to say that the proportion of eye makeup is very large and the eyes influence the impression (Kor. J. Aesthet. Cosmetol., 12(2), 211-216. 2014).

Eyelashes are the hair on the body and belong to short hair. Eyelashes are composed of amino acids such as glutamic acid, tyrosine, and phenylalanine, and have growth cycles of growth, decline, and resting phases like other hair in the body. After a growth period of about 3 to 5 months, it falls off as 6 months pass, and repeats creation, growth, and fallout. Eyelashes located on the upper and lower outermost eyelids of the eyelids have protective, lubricating, and aesthetic functions that prevent sweat, dust, and rainwater from entering the eyes.

Eyelashes can express a three-dimensional and attractive impression with various eyelash beauty methods. Beauty tools and methods for eyelashes include an eyelash curler that uses a curler, a tool that curls the eyelashes upward, mascara that fixes the curls to make them look fuller and longer after curling them with a curler, and curls well with a curler. There are methods such as using an eyelash straightener to raise short eyelashes that do not fit, a method to attach artificial eyelashes every time you do makeup, and eyelash extensions to lengthen human hair by extending the hair on one strand of human hair. However, in the case of using an eyelash curler or an eyelash curler, it is cumbersome to apply it every makeup, and additional use of mascara is essential as it is vulnerable to oil and moisture. The risk is great. In addition, in the case of eyelash extensions, there are disadvantages such as discomfort due to the feeling of a foreign body due to the alopecia.

Under this background, the present inventors have completed the present invention by developing a composition for eyelash perm that is safe and easy to use with low irritation using natural raw materials.

One object of the present invention is a first agent comprising a reducing agent, mineral oil and a natural extract; and a second agent comprising an oxidizing agent and a natural extract; as a composition for eyelash perming, wherein the natural extract is a white willow bark extract, an oregano leaf extract, a cypress leaf extract and a broiler bark extract. is to provide

Another object of the present invention is to provide a method of perming eyelashes using the composition for perming eyelashes.

This will be described in detail as follows. Meanwhile, each description and embodiment disclosed in the present invention may be applied to each other description and embodiment. That is, all combinations of the various elements disclosed herein fall within the scope of the present invention. In addition, it cannot be considered that the scope of the present invention is limited by the specific descriptions described below.

One aspect of the present invention for achieving the above object is a first agent comprising a reducing agent, mineral oil and a natural extract; and a second agent comprising an oxidizing agent and a natural extract; as a composition for eyelash perming, wherein the natural extract is a white willow bark extract, an oregano leaf extract, a cypress leaf extract and a broiler bark extract. provides

As used herein, the term "eyelash perm" refers to a technique of forming a wave that can be maintained for a long time by changing the natural eyelash hair tissue using a physicochemical method on the same principle as a hair perm. The present invention includes, without limitation, materials or products for eyelash perming, as well as the wave forming technique itself.

The composition for eyelash perm of the present invention is composed of a first agent having a reducing action and a second agent having an oxidizing action.

The first agent of the present invention may exhibit a viscosity of 130,000 to 150,000 cps (centipoise), and the second agent may exhibit a viscosity of 400,000 to 600,000 cps. This has a high viscosity compared to that of a general eyelash perm solvent, and is a sticky formulation that does not flow down. can do.

The first agent of the present invention includes a reducing agent, mineral oil and a natural extract.

Specifically, the reducing agent may include ethanolamine thioglycolate (ethanolamine thioglycolate) and cetearyl alcohol, glyceryl stearate (glyceryl stearate) and hydroxyethylcellulose (hydroxyethylcellulose) in addition may include The ethanolamine thioglycolate is a salt of ethanolamine and thioglycoic acid, and is a reducing agent used in permanent wave or hair straightener products. It is a component of the first alkaline reducing agent, that is, an emollient, and is added to break the cystine bond of the eyelashes to remove the elasticity of the eyelash hair. Preferably, in the present invention, the ethanolamine thioglycolate may be included in an amount of less than 8% by weight based on the weight of the first agent.

The term "mineral oil" of the present invention is a substance composed of saturated hydrocarbons having 10 to 50 carbon atoms obtained in the process of refining petroleum, and helps to prevent dryness by protecting the skin and blocking moisture evaporation. can give The mineral oil is included in the composition for perming eyelashes of the present invention to form an oil film on the surface of the eyelashes to prevent external irritation and to prevent the escape of moisture inside the eyelashes.

The second agent of the present invention includes an oxidizing agent and a natural extract.

Specifically, the oxidizing agent may include stearyl alcohol and sodium bromate, and further include cetearyl alcohol and ceteareth-12. can The stearyl alcohol is a mixture of higher aliphatic alcohols. It is a compound of stearic acid, a fatty acid that exists in nature, and is a component obtained by hydrolyzing and refining palm oil and palm oil. It has an effect of preventing drying and softening the skin and hair, and can serve as an emulsion stabilizer that helps various substances mixed in the composition of the present invention to be stably mixed.

"Natural extract" of the present invention is to include white willow bark extract, oregano leaf extract, cypress leaf extract and broiler bark extract. The white willow bark extract, oregano leaf extract, cypress leaf extract, and broiler bark extract of the present invention can be extracted by directly extracting the raw material, or can be used by purchasing an extract product distributed in the market, and the method of obtaining is not limited. does not

The term "extract" of the present invention means that if the active ingredient contained in the extraction raw material can be separated from the active ingredient contained in the extraction raw material by contacting the solvent and the extraction raw material under specific conditions, all of them will be included regardless of the extraction method or the type of active ingredient can For example, extracts of components soluble in solvents from raw materials using water or an organic solvent, and extracts obtained by extracting only specific components such as specific components of raw materials, such as oil, may be included. The extract may be powdered after drying, or may be obtained by various conventionally known extraction methods such as hot water extraction and ethanol extraction. The extract is selected from the group consisting of water, anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, acetone, petroleum ether, ethyl acetate, butyl acetate, trichloromethane, dichloromethane, chloroform, hexane and 1,3-butylene glycol It can be extracted with one or more solvents.

The extract may also include an extract that has undergone a conventional purification process. For example, the extract is separated using an ultrafiltration membrane having a constant molecular weight cut-off value, and various purification methods are additionally performed, such as separation by various chromatography (prepared for separation according to size, charge, hydrophobicity or affinity). It may include a fraction obtained through

As used herein, the term " salix alba bark" has been used as an antipyretic and analgesic agent in the West and China since ancient times, and its extract contains abundant amounts of salicin, polyphenol, etc. is known Although the analgesic efficacy, anti-aging effect, anti-inflammatory effect, etc. of the white willow bark extract have been reported, it is included in the composition for eyelash perm and has not been studied at all on the eyelash protection effect.

The term "oregano ( Origanum vulgare )" of the present invention has been widely used as a traditional medicine for respiratory diseases, pain, rheumatoid arthritis, and the like, and has been reported for the antioxidant and antibacterial activity of oregano oil. However, since oregano leaf extract is included in the composition for eyelash perm, there has been no research on the eyelash protection effect.

As used herein, the term "cypress ( Chamaecyparis obtusa )" belongs to the cypress family, and the anti-inflammatory effect of cypress oil and the antibacterial effect of cypress leaf extract have been reported. However, since the cypress leaf extract is included in the composition for eyelash perm, there has been no research on its eyelash protection effect.

The term "cinnamon tree ( Cinnamomum cassia )" of the present invention is an evergreen tree belonging to the camphor family, the bark of which is also called cinnamon and is used as a spice. Although the antioxidant, anti-inflammatory, and antibacterial activity of broiler bark has been reported, there has been no study on the eyelash protection effect of broiler bark extract as it is included in the composition for eyelash perm.

The natural extract of the present invention contains 4 parts by weight of white willow bark extract, 2 parts by weight of oregano leaf extract, 1 part by weight of cypress leaf extract and 1 part by weight of broiler bark extract.

In a specific embodiment of the present invention, comparative evaluation of the degree of damage to eyelashes after preparing a comparative example natural extract with different contents of each component, and performing eyelash perm using a composition for eyelash perm comprising the natural extract was (Experimental Example 1). As a result, Example 1 eyelash perm composition comprising 4 parts by weight of white willow bark extract, 2 parts by weight of oregano leaf extract, 1 part by weight of cypress leaf extract and 1 part by weight of cinnamon bark extract had the lowest rate of reduction in eyelash thickness after the procedure. , it was confirmed that the shape of the eyelashes was also preferable to the C-curl shape. That is, there is a difference in the effect related to the prevention of eyelash damage according to the content of each natural product, and the present invention is characterized in that the content ratio of each component showing the most excellent synergistic effect was identified.

In another specific embodiment of the present invention, a clinical evaluation of the skin irritation of the composition for perming eyelashes of the present invention was performed (Experimental Example 2). As a result, no skin reaction was observed at each observation time point after patch removal in all subjects who participated in the first and second agents included in the composition for perming eyelashes of the present invention. From the side, it was found that it was a substance in the hypoallergenic category.

In the composition for eyelash perm of the present invention, in addition to the above essential ingredients in each formulation, other ingredients may be appropriately blended within the range that does not impair the purpose according to the present invention, depending on the type or purpose of use, etc. of the formulation. The composition for treatment of the present invention may include a conventionally acceptable carrier, for example, oil, water, surfactant, humectant, lower alcohol, thickener, chelating agent, colorant, preservative, fragrance, etc. may be appropriately blended, The present invention is not limited thereto. The acceptable carrier may vary depending on the formulation. The composition for eyelash perm may include, without limitation, components commonly included in the industry in the manufacture of eyelash perms. Specifically, glyceryl stearate, hydroxyethyl cellulose, ethanolamine, propylene glycol, PEG-100 stearate, sorbitan sesquioleate, butylene glycol, lanolin, phenoxyethanol, PEG-40 Hydrogenated castor oil, sodium citrate, and citric acid may be further included.

Another aspect of the present invention provides an eyelash perm treatment method using the composition for eyelash perm.

Specifically, the treatment method of the eyelash perm includes the steps of (a) attaching a rod to the eyelids, and attaching the eyelashes to the rod; (b) wiping 8 to 12 minutes after applying the first agent to the eyelashes; and (c) wiping 10 to 15 minutes after applying the second agent to the eyelashes.

The descriptions of the terms “first agent” and “second agent” are the same as described above.

The rod of the present invention may have a crown shape to maximize the attachment surface, but is not limited thereto.

The eyelash perm treatment method of the present invention is safe by reducing irritation while minimizing eyelash damage by including natural ingredients, and has a high viscosity, so anyone can perform the treatment by themselves, so it is very convenient to use.

Another aspect of the present invention provides a kit for eyelash perm comprising the composition for eyelash perm, rod, glue, eyelash nutrient, and tape.

The rod is a cylindrical rod-shaped tool for fixing eyelashes so that various curl shapes can be made.

The glue is an adhesive that firmly fixes the rod and the eyelashes.

The eyelash nutrient is a nutrient in a liquid form that can be applied to the eyelashes from time to time to increase curl retention and additionally prevent damage to the eyelashes.

The tape serves to hold the eyelids from being covered.

The composition for perming eyelashes of the present invention contains various eco-friendly ingredients, so it is possible to safely perm the eyelashes without skin irritation or damage to the eyelashes, and has a high viscosity and is very convenient to use.

Hereinafter, the present invention will be described in more detail through examples. However, these examples are for illustrative purposes only, and the scope of the present invention is not limited to these examples.

Preparation Example 1. Preparation of composition for eyelash perm

In order to confirm the effect according to the content ratio of each component of the natural extract contained in the composition for perming eyelashes of the present invention, the natural extracts of Examples and Comparative Examples were prepared at the ratios of Table 1 below.

division
(Unit: parts by weight) Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 White Willow Bark Extract 4 2 One One Oregano Leaf Extract 2 2 One 4 Cypress Leaf Extract One 2 4 2 Broiler Bark Extract One 2 2 4

Next, the first agent comprising the natural extract, reducing agent, and mineral oil of Examples and Comparative Examples in Table 1; and a second agent comprising the natural extract and an oxidizing agent; a composition for eyelash perm was prepared. Specifically, the reducing agent of the first agent includes ethanolamine thioglycolate and cetearyl alcohol, and the oxidizing agent of the second agent includes stearyl alcohol and sodium bromine. mate (sodium bromate). In addition to the above-mentioned active ingredients, surfactants, preservatives, oxidizing agents, etc. necessary for the preparation of the solvent for eyelash perm are included in the required amount, and the viscosity of the first agent is 130,000 cps (centipoise) and the viscosity of the second agent is 400,000 to 600,000 cps. It was prepared by a method conventional in the art by adjusting. In addition, in addition to the compositions of Example 1 and Comparative Examples 1-3 containing the natural extract of the present invention, a commercially available solvent for eyelash perm was used as the composition of Comparative Example 4 and the following experiments were carried out.

Experimental Example 1. Measurement of damage to eyelashes

For 20 women in their 20s to 30s who have not undergone eyelash treatment, eyelash perming was performed using the composition for eyelash perming of Examples and Comparative Examples of the present invention, and each subject's eyelashes were collected after 30 minutes to collect eyelashes. The thickness and shape of the were measured. The change in the thickness of the eyelashes was measured with a 60x lens using an ASG device to measure the decrease in the thickness of the eyelashes before the eyelash perm, and the shape of the eyelashes was observed with the naked eye. In addition, the subjective satisfaction during the procedure was evaluated using a 10-point scoring method.

Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Eyelash thickness reduction rate 1.4% 3.1% 3.9% 2.0% 6.8% eyelash shape C curl curve bend C curl curve C curl curve bent shape satisfaction 8.7 7.5 7.3 8.1 6.2

As a result, as shown in Table 2, when the eyelash perm was performed using the composition of Example 1, it was confirmed that the thickness of the eyelashes decreased the least compared to the composition of Comparative Example 1-3 containing the natural extract in different content ratios. These results show that due to the mixing of a certain ratio of various natural ingredients contained in the natural extract of Example 1 of the present invention, an effective synergistic effect for preventing eyelash damage was found.

In addition, in the case of Comparative Example 4, which is a commercially available general eyelash perm solvent, not only the thickness of the eyelashes after the procedure was significantly reduced, but also due to the thin eyelashes, it was confirmed that the shape of the eyelashes after the procedure was partially bent in a L-shape rather than a soft curved shape. could

On the other hand, with respect to the subjective satisfaction during the procedure, the composition for eyelash perming of Example 1 had a high viscosity and could be applied to the eyelashes without flowing down, but in the case of Comparative Example 4, the eyelash perm had a low viscosity due to the low viscosity. Satisfaction ratings were low because it could get into the eye area or flow down around the eyes.

Experimental Example 2. Clinical evaluation of skin irritation

In order to confirm the human skin safety of the composition for eyelash perm in Example 1 of the present invention, a human application test was requested to MariDM Dermatology Research Institute, and related regulations of GCP (good clinical practice) and MFDS (ministry of food and drug safety) proceeded according to

The subjects were 30 healthy women who met the test subject selection criteria and did not meet the exclusion criteria, and the average age was 35.8±8.1 years old. After 20 μl of each of the first and second agents included in the composition for eyelash perm of the present invention was dropped into a Finn chamber, the test site of the subject was wiped with 70% ethanol, dried, and then the prepared test material was attached. The test substance is occluded or semi-occlusive for 48 hours. After the patch is removed, the test site is marked with a marking pen, and 30 minutes and 24 hours after the patch is removed, under a magnifying glass (RT207L, Sangacosmetic, Korea). Skin reactions were observed. Skin reaction evaluation was evaluated according to Table 3 below, which is a criterion reflecting Frosch & Kligman 1979, PCPC guideline, and International Contact Dermatitis Research Group (ICDRG).

score description 0 no response 0.5 Suspicious or faint erythema reaction One Weak but distinct erythema reaction 2 Erythema reaction accompanied by papules or edema with distinct erythema 3 Strong erythematous reaction with edema and papules 4 Erythema reaction with edema and blisters

The skin reactivity to each material at 30 minutes and 24 hours after patch removal was calculated as follows, and skin irritation was determined based on this.

Skin Reactivity = [∑(Score x No. of Responders) / {4(Maximum score) x (Total subjects)}] x 100

matter 30 minutes after patch removal 24 hours after patch removal 0.5 One 2 3 4 reactivity 0.5 One 2 3 4 reactivity Article 1 - - - - - 0.00 - - - - - 0.00 second agent - - - - - 0.00 - - - - - 0.00

As a result, as shown in Table 4, the first agent and the second agent included in the composition for perming eyelashes of the present invention showed no skin reaction at each observation time point after patch removal in all participants in the study. That is, the composition for perming eyelashes of the present invention was found to be a material of the hypoallergenic category in terms of primary stimulation of human skin.

From the above description, those skilled in the art to which the present invention pertains will understand that the present invention may be embodied in other specific forms without changing the technical spirit or essential characteristics thereof. In this regard, it should be understood that the embodiments described above are illustrative in all respects and not restrictive. The scope of the present invention should be construed as being included in the scope of the present invention, rather than the above detailed description, all changes or modifications derived from the meaning and scope of the claims to be described later and their equivalents.

Claims (5)

a first agent including a reducing agent, mineral oil and a natural extract; and
A composition for eyelash perm comprising; a second agent comprising an oxidizing agent and a natural extract,
The reducing agent includes ethanolamine thioglycolate and cetearyl alcohol, and the oxidizing agent includes stearyl alcohol and sodium bromate,
The first agent represents a viscosity of 130,000 to 150,000 cps, and the second agent represents a viscosity of 400,000 to 600,000 cps,
The natural extract contains 4 parts by weight of white willow bark extract, 2 parts by weight of oregano leaf extract, 1 part by weight of cypress leaf extract and 1 part by weight of broiler bark extract,
The first and second agents are glyceryl stearate, hydroxyethyl cellulose, ethanolamine, propylene glycol, PEG-100 stearate, sorbitan sesquioleate, butylene glycol, lanolin, phenoxy Ethanol, PEG-40 hydrogenated castor oil, sodium citrate, and a composition for eyelash perm that further comprises citric acid.
delete delete delete (a) attaching the rod to the eyelids and attaching the eyelashes to the rod;
(b) wiping after 8 to 12 minutes after applying the first agent of claim 1 to the eyelashes; and
(c) wiping after 10 to 15 minutes after applying the second agent of claim 1 to the eyelashes;