KR102374877B1 - Dietary herbal composition, dietary herbal medicine pill comprising the same and method for manufacturing thereof - Google Patents

Abstract

The present invention relates to an herbal composition for weight loss, and more particularly, to an herbal composition for weight loss that can prevent various diseases caused by overweight or obesity by effectively reducing body weight without any side effects to the human body, and using the same It relates to an herbal medicine pill for weight loss and a method for manufacturing the same.

Description

Herbal medicine composition for weight loss, herbal medicine pill for weight loss containing same, and method for manufacturing the same

The present invention relates to an herbal composition for weight loss, and more particularly, to an herbal composition for weight loss that can prevent various diseases caused by overweight or obesity by effectively reducing body weight without any side effects to the human body, and using the same It relates to an herbal medicine pill for weight loss and a method for manufacturing the same.

The root of the typical adult disease of modern people is from obesity. Obesity refers to a state in which the amount of stored adipose tissue is abnormally increased. In general, obesity refers to when fat accounts for more than 30% of body weight.

Causes of obesity include genetic factors, environmental factors such as irregular eating habits, lack of exercise, or excessive consumption of fast food, psychological factors such as depression and excessive stress, and hormonal factors caused by changes in thyroid or adrenal cortex hormones. .

Obesity is caused by the accumulation of unnecessary fat in the body because the amount of calories consumed is greater than the amount of energy consumed. it should be done

On the other hand, when fat accumulates in the body, the smooth body metabolism is disturbed and the function of the internal organs is lowered, which leads to diseases such as diabetes, high blood pressure, arteriosclerosis, hyperlipidemia, cardiovascular disease, fatty liver and other adult diseases and metabolic abnormalities. become the root cause of

After a significant amount of fat has accumulated in the body, it is difficult to lose weight even if you combine diet and exercise through diet. This is because fat is in a state that is easier to accumulate in the body.

In the case of excessive diet, excessive exercise, or indiscreet drug abuse in a state where the body's metabolic function is significantly lowered, a slight weight loss can be expected, but it can cause side effects such as extreme hunger, helplessness, and dizziness. do. In addition, in the case of reducing the weight by simply reducing the amount of food, the yo-yo phenomenon is accompanied by the harmful effect of gaining more weight than before.

Therefore, recently, in order to simultaneously solve problems such as the yo-yo phenomenon after dieting, excessive stress from excessive dieting, and a feeling of hunger or helplessness during diet, oriental diet therapy that reduces fat accumulated in the body while maintaining the balance in the body is in the spotlight are receiving

One of these oriental diet therapy is a composition that is prescribed by mixing various oriental medicines, but there is a problem that the weight loss effect is insignificant or it takes a long time to show the weight loss effect.

Registered Patent Publication No. 10-1969236

The present invention was devised in consideration of the above points, and by using herbal medicines as the main raw material, it is possible to effectively reduce body weight without any side effects to the human body, thereby preventing various diseases caused by overweight or obesity. It is an object to provide a composition.

In addition, the present invention exhibits a remarkable effect on weight loss while ingesting a small amount by using the herbal composition according to the present invention, and provides an herbal medicine pill for weight loss realized as a pill without a separate excipient and a method for manufacturing the same. Another object is there is.

In order to solve the above problems, the present invention provides an herbal composition for weight loss comprising ephedra, malt, dermis and maekmundong.

According to an embodiment of the present invention, it may include 90 to 110 parts by weight of malt, 90 to 110 parts by weight of dermis, 90 to 110 parts by weight of maekmundong based on 100 parts by weight of ephedra.

In addition, the herbal composition may further include antlers. In this case, the antler may be included in an amount of 15 to 30 parts by weight based on 100 parts by weight of ephedra.

In addition, the present invention comprises the steps of (1) preparing an herbal composition according to the present invention; (2) pulverizing some of the prepared herbal composition into powder, and extracting the rest with hot water to prepare a broth; And (3) mixing the powder and broth to prepare a pill; provides a method for producing herbal medicine pills for weight loss comprising.

According to an embodiment of the present invention, the hot water extract is a concentrate, and the concentrated liquid is prepared by boiling the hot water extract to have a volume of 1/70 to 1/90 of the total volume of the hot water extract extracted with hot water at 90 to 105 ° C. can

In addition, the present invention provides a herbal medicine pill for weight loss, wherein the powder of the herbal composition according to the present invention is mixed with the hot water extract concentrate for the herbal composition to have a predetermined shape.

According to an embodiment of the present invention, the herbal medicine pill may not contain a separate excipient.

According to the present invention, by using herbal medicine as a main raw material, there is no side effect on the human body, and the absorption rate in the body is high, so that the body weight is effectively reduced, and thus it is effective to prevent various diseases caused by overweight or obesity. In addition, herbal medicine pills prepared through this can be achieved by conveniently ingesting a small amount of pills by providing the active ingredient of the composition according to the present invention effective for weight loss in the maximum content within the limited volume of the pill. there is. Furthermore, there is an advantage in that the content of the active ingredient in the ring can be further increased as the pill is easily manufactured without using an excipient normally used in manufacturing the herbal medicine ring.

Hereinafter, embodiments of the present invention will be described in detail so that those of ordinary skill in the art can easily implement them. The present invention may be embodied in many different forms and is not limited to the embodiments described herein.

The herbal composition for weight loss according to an embodiment of the present invention includes ephedra, malt, dermis and maekmundong.

The ephedra is a generic term for plants of the genus Ephedra and has been widely used as a herbal medicine since ancient times. Ephedrine contains the alkaloids ephedrine and methylephedrine, similar to the adrenaline action of the adrenal medulla, it stimulates the end of the sympathetic nerve. In addition, ephedra promotes tropical death and causes anorexia and is used to treat obesity. Ephedra contains a large amount of alkaloids as a component, and the main components are L-ephedrine and D-pseudoephedrine, which inhibit cholesterol absorption in the small intestine of the human body and increase energy consumption in adipose tissue. It acts to accelerate the rate of fat breakdown. However, since ephedra causes insomnia due to over-excitation of the parasympathetic nerve or side effects such as paralysis of the tongue, it is preferable to use only the appropriate amount, which will be described later.

In addition, the malt is effective for digestive disorders due to weak stomach, and is particularly useful for indigestion of carbohydrates. In addition, it has a digestion promoting action and a blood sugar lowering action.

In addition, the palpitation is effective in treating diseases of the respiratory system, such as dry cough, hematemesis, and hemoptysis. In addition, it has the function of preventing and increasing the damage of the sap in the body, so it helps to prevent constipation that can occur during diet.

In addition, the dermis refers to the mature pericarp of tangerine (Citrus unshiu Markovich) or a closely related plant of the rutaceae family. It relieves qi clumping and strengthens the function of the spleen to relieve stomach upset, belching, vomiting, nausea, indigestion, flatulence. It treats the symptoms of calling and drowsiness and loose stools, removes seawater and phlegm, and has a diuretic effect. In addition, the dermis contains a large amount of essential oil and is known to have excellent pharmacological effects such as digestive stimulation, digestion promotion, expectoration, anti-ulcer, anti-gastric secretion, strong heart, blood pressure increase, anti-allergy, biliary secretion promotion, uterine smooth muscle suppression, and antibacterial action. there is. As the dermis improves qi circulation and promotes metabolism, it has an effect on suppressing obesity and contains hesperetin, which lowers cholesterol.

The herbal composition for weight loss according to an embodiment of the present invention contains the above-mentioned ephedra, malt, maekmundong and dermis. There is a concern that if any one of these ingredients is not included, it is difficult to exert the increased weight loss effect, or it is impossible to prevent or minimize the side effects caused by any one drug. For example, if ephedra is not included, the weight loss effect may be significantly lowered, and if any one of malt, mammary gland and dermis is not included, symptoms such as headache, insomnia, heart palpitations, spermatozoa may occur, or these symptoms may intensify. there is.

The herbal composition for weight loss according to an embodiment of the present invention may include 90 to 110 parts by weight of malt, 90 to 110 parts by weight of dermis, 90 to 110 parts by weight of maekmundong, and for example, these are 4 Eggplant components may be mixed in a weight ratio of 1:1:1:1. When the content of these four components satisfies the preferred range of the present invention, it is possible to minimize side effects due to herbal medicines while exhibiting a more elevated effect in weight loss.

In addition, the herbal composition may further include antlers in addition to these four components. The antler refers to dried antlers from freshly grown stags. From mid-March every year, deer's old antlers fall off and new antlers begin to sprout. Ganglioside, a type of glycolipid among the fat-soluble components of deer antler, is a high molecular weight glycolipid accumulated in the gray matter of the kidney, liver, spleen, and brain, and is known to be effective in diabetes and neurotoxicosis. When appetite is controlled for weight loss, food intake is reduced and physical strength is lowered, energy is lowered, and it is easy to lower motivation. Accordingly, when deer antlers are included together with ephedra, malt, dermis and maekmundong, even when diet is controlled, stamina does not decrease and the metabolic rate increases, thereby exhibiting a more elevated weight loss effect. The antler may be included in an amount of 15 to 30 parts by weight based on 100 parts by weight of ephedra, and if less than 15 parts by weight of antler is included, it may be difficult to achieve an increased effect on weight loss, and if it exceeds 30 parts by weight, weight loss The increase in the effect may be insignificant, there is a risk of side effects, and on the contrary, depending on the user, there may be a concern that there is no weight loss effect or, conversely, weight increase.

In addition, the herbal composition may further include any one or more of ortho chiffon and multi-leaf, through which there is a more elevated effect on weight loss through diuretic effect, body fat decomposition effect, basal metabolic rate increase, etc., more preferably may include both ortho chiffon and multi-leaf.

In addition, in consideration of the patient's constitution, in addition to the above-mentioned ingredients, herbal medicines such as Sukjihwang, Euiin, Sansa, Jade Bal, Songyeop, Longanyuk, Baekbokryeong, Changjo, Wooseul, Angelica, Cheongung, Somok, Ayeop, Honghwaja, Ogapi, Hwanggi, Licorice, etc. Any one or more may be further included.

In addition, the present invention includes herbal medicine pills for weight loss using the herbal composition according to the present invention as described above, wherein the herbal medicine pill for weight loss includes (1) preparing the above-described herbal composition, (2) some of the prepared herbal composition It can be prepared including the steps of pulverizing into a powder, extracting the remainder with hot water to prepare a broth, and (3) mixing the powder and broth to prepare a pill.

Step (1) is a step of preparing the herbal composition, and each drug included in the herbal composition may be commercially available, for example, a dried product, but is not limited thereto.

In addition, the step (2) is a step of preparing a powder and broth, which are raw materials when manufacturing the ring in step (3). A part of the prepared herbal composition is pulverized and manufactured into powder, and the present invention is not particularly limited thereto since a known method for pulverizing oriental medicine may be used for the pulverization process. At this time, the amount of the herbal composition to be pulverized may be 20 to 45% by weight based on the total weight of the prepared herbal composition, for example, it may be 23% by weight.

The remaining unpulverized herbal composition is used to prepare a broth and is subjected to a hot water extraction process. The hot water extraction process may be a conventional process for manufacturing herbal ingredients in a tangjeon. For example, after immersing the prepared medicinal material in water, it is preheated at a temperature of 90 to 105° C. for 30 minutes to 90 minutes, and then extracted for 2 to 4 hours. can At this time, the amount of water may be added by 1 to 60 times the weight based on the total weight of the injected drug. In addition, the hot water extraction may be performed multiple times, for example, after filtering the hot water extract after one time of hot water extraction, water is added to the remaining residue, and the same hot water extraction process and the filtration process after extraction are performed one or more times. can When the hot water extraction process is performed multiple times, the hot water extract extracted at each time may be added.

On the other hand, the broth can make the powder of the herbal composition well agglomerate and make a predetermined shape without a separate excipient, for example, glutinous rice flour or honey, which are commonly used when preparing the pills in step (3). It may be a concentrate having a predetermined viscosity so as to To this end, the hot-water extract prepared in the above-described hot-water extraction process may be further subjected to a concentration process such that the volume is 1/70 to 1/90 of the total volume of the hot-water extract. The concentration process may be a conventional concentration process, but may be, for example, a bath using water, and more specifically, an ultra-high-speed low-temperature vacuum concentrator may be used, and the temperature may be 85 to 95°C. By concentrating the hot water extracted broth through this concentration, for example, 20 times, it is possible to consume a high content of active ingredients in a small amount compared to when using unconcentrated broth, so that the same effect as the decoction can be more significantly expressed. There are advantages that can be

Next, as step (3) according to the present invention, a step of preparing a pill is performed by mixing the powder prepared in step (2) with the broth. In this case, the broth may be a concentrated liquid obtained by concentrating the broth as described above. In addition, the powder and the broth can be mixed in a weight ratio of 1.8 to 2.2: 1, and through this, a more improved weight loss effect can be obtained, and at the same time, it can be easily manufactured into a ring having a predetermined shape without an excipient. In addition, the round dough in which the powder and the broth are mixed may be prepared to have a predetermined shape thereafter, and may be extruded in an extruder for example and then cut to have a predetermined length. The dough prepared to have a predetermined shape may then be subjected to a drying process. As the drying process, a conventional drying process such as natural drying or hot air drying may be appropriately employed, and the drying time may vary depending on the drying method, so the present invention is not particularly limited thereto.

On the other hand, the herbal composition according to an embodiment of the present invention may be prepared as a tablet. The tablet may be prepared into a powder by freeze-drying the concentrated broth prepared in step (2) during the process of manufacturing the above-mentioned pill, and then manufactured into a tablet through a conventional tableting process. In this case, the tablet may include the powder prepared in step (2) of the process for preparing the above-mentioned pills together with the lyophilized powder, or it may include only the lyophilized powder.

The herbal medicine pills prepared through the above-mentioned manufacturing method are prepared to have a predetermined shape by mixing the herbal medicine composition powder with the hot water extract concentrate for the herbal medicine composition, and may not contain a separate excipient, so the active ingredient contained in the pill in a limited amount Since the amount of the drug can be significantly increased, the weight loss effect can be further increased compared to the dosage, and there is an advantage in that it is possible to prevent side effects such as allergies due to excipients. Furthermore, the effect is very excellent even compared to the simple pulverization and powdering of the herbal composition.

The present invention will be described in more detail through the following examples, but the following examples are not intended to limit the scope of the present invention, which should be construed to aid understanding of the present invention.

<Example 1>

As an herbal composition, 100 parts by weight of malt, 100 parts by weight of maekmundong, 100 parts by weight of dermis and 20 parts by weight of antler based on 100 parts by weight of ephedra were prepared. Then, 25% of the weight of the prepared herbal composition was put into a grinder and powdered. In addition, the rest of the herbal composition was immersed in water 6 times the weight of the drug, preheated at 100° C. for 1 hour, and extracted with hot water for 3 hours. Thereafter, a primary hot water extract was obtained by filtration, and the filtered and remaining medicinal materials were again subjected to hot water extraction under the same conditions, followed by filtration to obtain a secondary hot water extract. After combining the obtained primary and secondary hot water extracts, a concentrated solution was prepared which was concentrated to a volume of 1/40 based on the volume of the hot water extract before concentration using a 92°C ultra-high-speed low-temperature vacuum concentrator.

Then, the powder and the concentrate were mixed in a weight ratio of 2:1, kneaded by machine, extruded, cut to a predetermined length, and dried in a dryer for 10 hours to prepare herbal medicine pills.

<Example 2>

It was prepared in the same manner as in Example 1, but by changing the ingredients as shown in Table 1 below, herbal medicine pills were prepared.

<Comparative Examples 1 to 4>

It was prepared in the same manner as in Example 1, but by changing the ingredients as shown in Table 1 below, herbal medicine pills were prepared.

<Experimental example>

After evaluating the weight loss effect on patients who visited an oriental clinic for the purpose of obesity treatment, the waist circumference of 90 cm for men and 85 cm for women was evaluated for adults, and the results are shown in Table 1 below. Specifically, waist circumference and weight were measured for each patient at the first visit. Afterwards, all patients were instructed to take the same number of herbal medicine pills for 60 days, and they were instructed to self-administer exercise therapy or diet according to the patient's situation, but not to exercise excessively, fasting, or fasting.

After 40 patients (20 males, 20 females) were continuously taking herbal medicine pills according to Examples and Comparative Examples for each Example and Comparative Example, waist circumference and weight were measured for each patient in the same manner after 60 days. For each patient, the degree of reduction compared to the waist circumference at the first visit was calculated as a percentage, and the percentage reduction in waist circumference for 40 patients for each example/comparative example was calculated as an average value.

In addition, after taking herbal medicine pills after the first visit, a questionnaire was asked about the change in the feeling of satiety normally during the 60 days. The average of the survey results based on 3 for an increase and 4 for a large increase was added up. It can be interpreted that the higher the questionnaire result, the greater the increase in satiety.

In addition, it was evaluated whether side effects such as headache and insomnia occurred during 60 days while taking herbal medicine pills after the first visit. After counting the number of patients who felt these side effects for 3 days or more for 60 days, it was calculated as a percentage.

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Ephedra (parts by weight) 100 100 100 100 100 not included Malt (parts by weight) 100 100 100 100 not included 100 Maekmundong (parts by weight) 100 100 100 not included 100 100 Dermis (parts by weight) 100 100 not included 100 100 100 Deer antler (parts by weight) 20 not included not included not included not included not included Average weight (kg) at first visit for 40 people 73.7 70.1 72.5 73.8 70.5 72.6 Percentage of people who lost less than 3% of their weight after evaluation (%) 5 7.5 20 25 37.5 50 Percentage of people who lost 8% or more of their weight after evaluation (%) 62.5 50 35 32.5 32.5 15 Average waist circumference reduction (%) 4.1 4.1 2.8 2.3 2.0 1.2 satiety 3.8 3.3 3.2 2.4 2.0 2.8 Side effect detection rate (%) 0 2.5 17.5 12.5 12.5 0

As can be seen in Table 1, it can be confirmed that the patient group taking the pills prepared by the herbal composition according to the embodiment of the present invention exhibits excellent weight loss effect while having few or no side effects.

Although one embodiment of the present invention has been described above, the spirit of the present invention is not limited to the embodiments presented herein, and those skilled in the art who understand the spirit of the present invention can add components within the scope of the same spirit. , changes, deletions, additions, etc. may easily suggest other embodiments, but this will also fall within the scope of the present invention.

Claims (8)

(1) preparing an herbal composition comprising 90 to 110 parts by weight of malt, 90 to 110 parts by weight of dermis, 90 to 110 parts by weight of maekmundong, and 15 to 30 parts by weight of antler with respect to 100 parts by weight of ephedra;
(2) Part of the prepared herbal composition is pulverized into powder, and the remaining herbal composition is immersed in water 1 to 60 times the weight of the total weight of the remaining herbal composition, and then preheated at 90 to 105° C. for 30 to 90 minutes 2 to 4 After extraction for a period of time, the hot-water extract was heated at 85-95° C. using an ultra-high-speed low-temperature vacuum concentrator to have a volume of 1/70 to 1/90 of the total volume of the extracted hot-water extract. preparing a broth; and
(3) preparing pills by mixing the powder and broth in a weight ratio of 1.8 to 2.2: 1; herbal medicine pills manufacturing method for weight loss, including. delete delete delete delete delete delete delete