KR102325161B1 - Composition for decreasing bad smell and treating demodex infestations of pet animal, and manufacturing mehtod thereof - Google Patents

Abstract

The present invention relates to a composition for removing Demodex and odor removal in companion animals and a method for manufacturing the same, and more particularly, preparing a raw material containing quince, mulberry bark, yellow lily, cinnamon, baekduong, cypress, arborvitae and eoseongcho and mixing and fermenting the raw material with EM stock solution, molasses, sea salt and water, ultrasonically extracting the fermented raw material, plasma-treating the ultrasonically extracted extract, and the plasma-treated extract It is characterized in that it comprises the steps of distillation extraction, and filtering the distillation-extracted extract. According to the present invention, there is an advantage in that it is possible to effectively remove the unique odor emitted from the body of the companion animal, and to prevent and treat Demodexosis through the excellent sterilization function of Demodex mites.

Description

Composition for decreasing bad smell and treating demodex infestations of pet animal, and manufacturing mehtod thereof

The present invention relates to a composition for removing Demodex and odor removal in companion animals and a method for manufacturing the same, and more particularly, comprising extracts of quince, mulberry bark, yellow lily, cinnamon, baekduong, cypress, arborvitae and eoseongcho as active ingredients. , Fermentation, ultrasonic extraction, plasma treatment, and distillation extraction of raw materials, thereby increasing the extraction efficiency, as well as maximizing the deodorization and Demodex removal effect, a composition for removing Demodex and odor removal of companion animals and a method for manufacturing the same will be.

The number of pets, such as dogs, being kept in the home rather than outside the home with family members is rapidly increasing. In particular, as the number of single or two-person households is rapidly increasing, their demand is increasing, and most of them are apartments or villas. However, when pets are kept indoors, there is a problem due to the peculiar smell emanating from the pet's body, mouth, and excrement.

The characteristic odor emitted from the companion animal's body is because the secretions discharged from the companion animal's skin glands are oxidized in the air and cause a bad odor. Therefore, people who keep companion animals used functional shampoos containing sterilizing ingredients to remove the peculiar odors of companion animals. However, the sterilizing active ingredients of existing functional shampoos are based on harmful chemical ingredients such as chlorhexidine and benzoyl peroxide. This occurred. Therefore, there is a demand for development of biologically-derived natural ingredients with high skin safety to replace these chemically active ingredients.

On the other hand, Demodex mites are ectoparasites that parasitize the skin and hair follicles. Among the various reported species, Demodex canis, Demodex Inzai, and Demodex Konei cause demodicosis in companion animals such as dogs and cats, causing itching, hair loss, pain, and spots. lesions, etc.

Conventionally, such a treatment of Demodexemia has generally used topical ointments, medicated shampoos, drugs, etc., but the treatment period is long and it is difficult to take drugs.

KR 10-2018-0106579 A KR 10-1724185 B1

Accordingly, it is an object of the present invention to effectively remove a unique odor emitted from the body of a companion animal, and to prevent and treat demodicosis through an excellent sterilization function. To provide a manufacturing method.

To achieve the above object, the method of preparing a composition for removing Demodex and odor of companion animals of the present invention for achieving the above object is to prepare a raw material containing step, mixing and fermenting the raw material with EM stock solution, molasses, sea salt and water, ultrasonically extracting the fermented raw material, plasma-treating the ultrasonically extracted extract, and the plasma-treated extract It is characterized in that it comprises the steps of distilling extraction, and filtering the distillation-extracted extract.

The plasma treatment is characterized in that after adding tourmaline and germanium to the ultrasonically extracted extract, plasma treatment is performed under a platinum catalyst.

The raw material is characterized in that it further comprises a hairy dew, Gabija tree and Ukriin.

The composition for removing Demodex and odor of companion animals according to the present invention is characterized in that it is prepared through the above-described method.

According to the present invention, there is an advantage in that it is possible to effectively remove the unique odor emitted from the body of the companion animal, and to prevent and treat Demodexosis through the excellent sterilization function of Demodex mites.

1 is a flowchart showing the manufacturing process of a composition for removing Demodex and odor in companion animals according to the present invention.

Hereinafter, the present invention will be described in detail.

First, the composition for removing Demodex and odor in companion animals according to the present invention may be provided in the form of a shampoo composition for companion animals or an external preparation for skin.

In this case, it is natural that other additives such as excipients that can be used normally when applied to the shampoo composition or other external preparations for skin may be further included.

In addition, the companion animal according to the present invention includes a dog or a cat, and includes all of the various animals that can be kept indoors.

The composition for removing Demodex and odor of companion animals according to the present invention comprises, as an active ingredient, an extract of raw materials including quince, mulberry bark, yellow lily, cinnamon, baekduong, cypress, arborvitae and eoseongcho, wherein the extract is a raw material It is characterized in that fermentation, ultrasonic extraction, plasma treatment, distillation extraction and filtering.

The raw materials used in the present invention will be briefly described.

The Galla Rhois refers to a nest formed by a stab wound of a rhus javanica L or a member of the family Rhus javanica L. They are called saphenous lobster, red buoyancy, anastomosis, and white chungchang. Obaeja is an irregular pouch shape, resembling the shape of a human ear, and is empty inside and has a very sour taste. Obaeja mainly contains 50-60% of tannins, so it is used as a raw material for tannins, hair dyes, and inks.

The Moutan Cortex Radicis refers to the root bark of the Paeoniaceae family, and the ingredients include paeonoside, paeonolide and paeonol, and paeonoside decomposes during storage to form sugars and phaeonols. As pharmacological action, antipyretic, anti-inflammatory, antithrombotic, anti-allergic, etc. have been reported.

The yellow lily (黃連) is an evergreen perennial plant of the Dicotyledonous Hemiptera, Heteroptera, which is native to China, but is also cultivated in Korea, Japan, and China for medicinal purposes, and is distributed in Russia and North America, and various species around the world. exist. In oriental medicine, the roots of 5 to 6 years old yellow lotus planted in November are collected and dried in the sun.

The cinnamon is a medicinal herb made from the bark of cassia belonging to the camphoraceae (Cinnamomum aromaticum Nees, Cinnamomum cassia auct, Cinnamomum cassia J Presl, Cinnamomum zeylanicum Blume var cassia Nees, Cinnamomum japonicum SIEB, Cinnamomum cassia BLUME). Cinnamon is called broiler chicken in oriental medicine and is mainly used for the treatment of anorexia and indigestion as a stomach acid.

The baekduong is a crude name of the halmi flower (Pulsatilla Koreana), and also refers only to the root of the halmi flower. Baekduong, the root of the genus flower, is rich in saponin, a hederagenin glucoside compound, and has been used as a medicinal in traditional Chinese medicine for pain relief, hemostasis, anti-inflammation, dryness, blood loss, windswept, acidosis, convergence, dysentery, branching, neuralgia, etc. In addition, it is a medicinal plant with various uses, such as using the insecticidal effect of the root as an insect repellent.

The cypress (Chamaecyparis obtusa) is a coniferous tree that has been successfully grown and settled in the southern regions of Korea after being planted in the southern regions of Korea, called cypress (檜木), hinoki, and cypress, which are native to Japan. The amount of phytoncide from cypress is superior to that of other hardwoods, so you can keep your scalp healthy and clean with its natural antibacterial effect. In the present invention, one or more of the leaves and roots of the cypress tree may be used.

The arborvitae leaf is a leaf of an evergreen tree of the coniferous arboraceae family. It is evergreen, obovate or ovate, scaly, and both sides are green or light yellow-green, and there are some white spots. Arborvitae leaf is known to contain a lot of phytoncide, a natural antibacterial component, and has a unique scent.

The Eoseongcho (Houttuynia cordata thunb) is an outpost of Yakmomil (Houttuynia cordata Thunb), which is a plant of the Saururaceae family, and inhabits in Southeast Asia and in particular, Japan and Korea. It has been reported that eoseongcho contains a lot of decanoyl acetaldehyde compounds that are effective in antibacterial, antiviral, and fungal suppression, and flavonoid-based compounds that are effective in diuresis, strong heart, and defecation.

The reason for using all eight kinds of raw materials in the present invention is because it is possible to effectively remove the pet's peculiar odor while also removing Demodex through the interaction between each raw material. This is because the sufficient effect required for this is not expressed.

The raw material does not limit the mixing ratio, but considering the deodorant and demodex removal effect, 50-150 parts by weight of mulberry bark, 50-150 parts by weight of hwangryeon, 50-150 parts by weight of cinnamon, 50-150 parts by weight of baekduong with respect to 100 parts by weight of quince Most preferably, 150 parts by weight, 50 to 150 parts by weight of cypress, 50 to 150 parts by weight of arborvitae, and 50 to 150 parts by weight of eoseongcho.

On the other hand, the present invention may further include 50 to 150 parts by weight of hairy dew, 50 to 150 parts by weight of Gabija, and 50 to 150 parts by weight of Ukriin, as the raw material, based on 100 parts by weight of the quince. When the hair dew, Gabija tree, and Ukriin are further included, it not only has an excellent deodorizing effect and demodex removal effect, but also treats and prevents hair loss due to skin lesions.

It is recorded that the hairy dew is a perennial herb of the needleaceae family that grows in the field, and was used in oriental medicine to reduce heat by detoxification. In the present invention, the outpost of the hairy dew can be used.

The Gabija tree (Cephalotaxus koreana) is a plant distributed in China, East India, Thailand, Japan and Korea, and is also called local birch (土香榧). In the present invention, one or more of the leaves and stems of the Gabija tree may be used.

The Ukriin (郁李仁) refers to the seeds of Prunus japonica Thunb var nakaii, P triloba var truncata Kom, P tomentosa Thunb, and P ishidoyana Nakai. .

The composition of the present invention maximizes the deodorizing ability and demodex removal ability while increasing the extraction efficiency by fermenting the raw materials, ultrasonic extraction, plasma treatment, distillation extraction, and filtering. When used, it has the advantage of being able to remove bad odors from the pet's body and to remove the demodex parasitic on the pet's skin or hair follicles.

Specific methods for fermentation of the raw materials, ultrasonic extraction, plasma treatment, distillation extraction and filtering will be described in detail through the method for preparing the composition below.

The composition according to the present invention may be included in the range of 0.1 to 50% by weight as an active ingredient in the shampoo composition for companion animals or the composition for external application for skin, but is not limited thereto.

Hereinafter, a method for preparing a composition for removing Demodex and odor in companion animals according to the present invention will be described.

As shown in FIG. 1, the method for preparing a composition for demodex removal and odor removal in companion animals according to the present invention comprises the steps of preparing a raw material containing quince, mulberry bark, hwangryeon, cinnamon, baekduong, cypress, arborvitae and eoseongcho; , mixing and fermenting the raw material with EM stock solution, molasses, sea salt and water, ultrasonically extracting the fermented raw material, plasma-treating the ultrasonically extracted extract, and distilling the plasma-treated extract It is characterized in that it comprises the step of extracting, and filtering the distillation-extracted extract.

Five Baeja, Mokdan Skin, goldthread , cinnamon, Baek Duong , cypress, arborvitae And preparing a raw material containing eoseongcho

First, prepare raw materials including baekjae, muldanpi, hwangryeon, cinnamon, baekduong, cypress, arborvitae and eoseongcho. At this time, the mixing ratio is based on 100 parts by weight of Obaeja, 50-150 parts by weight of mulberry bark, 50-150 parts by weight of yellow lily, 50-150 parts by weight of cinnamon, 50-150 parts by weight of baekduong, 50-150 parts by weight of cypress, 50 parts by weight of arborvitae. It is most preferred that it is ~150 parts by weight and 50 to 150 parts by weight of eoseongcho.

In addition, as described above, it may be prepared by further mixing 50 to 150 parts by weight of hairy dew as a raw material, 50 to 150 parts by weight of Gabija, and 50 to 150 parts by weight of Ukriin.

Since the present invention utilizes only natural raw materials, there is no toxicity, and there is an advantage that it can be used stably without side effects.

to the raw material EM Mixing and fermenting the stock solution, molasses, sea salt and water

Next, 2-4% by weight of EM stock solution, 2-4% by weight of molasses, 0.5-1.5% by weight of sea salt, and the remainder of water are mixed with 10-20% by weight of the raw material and fermented for 2-4 days at 37-40 ℃ do. In this case, any of commercially available products may be used as the EM stock solution.

The reason for fermenting the raw materials prior to extraction in the present invention is that the high-temperature extraction method has a risk of destruction of the active ingredient, and the cold-chilled extraction method has the disadvantage that it takes a long extraction time, but using the fermentation method does not destroy the active ingredient. This is because the extraction efficiency can be increased even without it.

Ultrasonic extraction of the fermented raw material

Next, ultrasonic extraction of the fermented raw material increases the extraction efficiency.

At this time, the wavelength at the time of the ultrasonic extraction is sufficient if about 18 ~ 21KHz, and extraction at 40 ~ 50 ℃ 40 ~ 50 hours is sufficient, but is not limited thereto.

The ultrasonically extracted extract plasma steps to process

Next, the ultrasonically extracted extract is put into the water tank of the liquid plasma processor, and plasma is generated by applying a voltage to the extract to plasma-treat the extract, thereby maximizing the deodorizing effect and the Demodex removal effect of the extract.

At this time, the plasma is a low-temperature plasma that is generated through the discharge of electromagnetic waves by applying a voltage between the two electrodes to form an electric field, and is an atmospheric pressure plasma that generates plasma at atmospheric pressure. The liquid plasma processor includes a tank in which to-be-treated water is stored, first and second electrodes for generating plasma, a power source, and the like, and it is natural that the conventionally disclosed liquid plasma processor can be used without limitation. Since the liquid plasma treatment device is already well known in the art to which this technology belongs, a detailed description thereof will be omitted.

More specifically, the plasma treatment is performed by adding tourmaline powder and germanium powder to the ultrasonically extracted extract in a weight ratio of 1:0.01 to 0.1:0.01 to 0.1, and then putting it into a liquid plasma processor, and applying a voltage under a platinum catalyst. By applying plasma to generate plasma, plasma ionized particles from the tourmaline powder and germanium powder are deposited on the surface of the active ingredients in the extract, thereby further activating the function of the active ingredient.

The reason for plasma-treating the extract in the present invention is that by plasma-treating the active ingredient in the extract, the plasma-treated active ingredient is transformed and acts when combined with the bio-ions of the skin, thereby activating its function and entering the cell. This is because the effect can be maximized by speeding the delivery to the In addition, the present invention removes the source of the odor by removing the cell wall of the odor-causing bacteria using the ion energy through the plasma-treated active ingredient, and the odor disappears by decomposing the molecules of the odor.

At this time, the generated voltage of the plasma is about 4.5 ~ 20V, the frequency is sufficient if about 1 ~ 30kHz, the processing time is enough about 3 ~ 5 hours, but is not limited thereto.

remind plasma Distilling the treated extract

Next, the plasma-treated extract is distilled and extracted at a temperature of 70 to 90° C. for 0.5 to 12 hours using a vacuum distillation extractor.

The distilled extract to filter step

Next, the distilled extract is filtered using a qualitative filter paper or the like.

In addition, it is natural that the filtered extract can be concentrated, concentrated, or dried as needed.

The composition of the present invention prepared by the above method has the advantage of being able to effectively remove the peculiar odor of companion animals, as well as being able to remove Demodex, as well as being used as an active ingredient in a shampoo for companion animals or an external preparation for skin.

Hereinafter, the present invention will be described in detail through examples.

(Example 1)

Five baeja, muldanpi, hwangryeon, cinnamon, baekduong, cypress leaf, arborvitae leaf, and eoseongcho 20g each were prepared and mixed. Next, 30 g of EM stock solution, 30 g of molasses, 10 g of sea salt, and 770 g of water were mixed, and the mixture was fermented at 38.5° C. for 3 days.

Next, the fermented product was extracted at 48° C. for 48 hours at a wavelength of 19.7 KHz using an ultrasonic extractor.

And after adding tourmaline powder and germanium powder to the ultrasonically extracted extract in a weight ratio of 1:0.05:0.05, it was put into a liquid plasma processor, and 19V under a platinum catalyst (ultrasonic extracted extract and platinum catalyst 100:1 by weight) Plasma was generated for 4 hours at a voltage of 10 kHz and a frequency of 10 kHz. At this time, the particle size of the tourmaline powder and germanium powder was 200 mesh, respectively, the electrode for plasma generation was a tungsten rod material with a diameter of 26 mm, and the distance between the electrodes was constant at 0.5 mm using a thickness gauge.

Next, the plasma-treated extract was distilled and extracted at a temperature of 80° C. for 4 hours using a vacuum distillation extractor, which was filtered and filtered three times with Whatman No. 4 filter paper. And it was vacuum-concentrated and freeze-dried.

(Example 2)

It was carried out in the same manner as in Example 1, except that, as raw materials, 15 g each of baekjae, mulberry bark, hwangryeon, cinnamon, baekduong, cypress leaf, arborvitae leaf, eoseongcho, hairy dew outpost, gabija leaf and ukniin were used.

(Comparative Example 1)

Prepare and mix 20 g each of five baeja, mulberry bark, hwangryeon, cinnamon, baekduong, cypress leaf, arborvitae leaf, and eoseongcho, add 10 times by weight of water, extract at 90°C for 12 hours, filter, and Whatman Filtered by filtration 3 times with No.4 filter paper. And it was vacuum-concentrated and freeze-dried.

(Test Example 1)

The samples of Examples 1, 2 and Comparative Example 1 were each diluted in purified water to a concentration of 100 μg/mL.

After separating Demodex from the dog's hair follicles, each sample was processed by placing it on a slide glass. The survival time was measured by covering the cover glass and observing the movement of the Demodex body and legs under an electron microscope. The survival time was measured from the time the sample was dropped to the time when the democytic body gradually shrank and the movement was terminated. The results are shown in Table 1 below.

Experimental Example 1 Results division survival time Example 1 14 minutes 30 seconds Example 2 11 minutes 20 seconds Comparative Example 1 22 minutes 40 seconds

As can be seen in Table 1, Examples 1 and 2 according to the present invention were confirmed to be excellent in the effect of inhibiting the survival of Demodex compared to Comparative Example 1.

(Test Example 2)

The samples of Examples 1, 2 and Comparative Example 1 were each diluted in purified water to a concentration of 100 μg/mL.

100ppm and 30ppm of ammonia and trimethylamine, respectively, were injected into each Tedlabag, which is a test container of 10L capacity, and then 10ml of the sample was injected into the Tedlarbag. Thereafter, the concentrations of ammonia and trimethylamine at 0.5 hours, 1 hour, 2 hours, 4 hours and 6 hours were measured. It was tested in the same way without adding a sample, and it was set as a blank test. And the results are shown in Tables 2 and 3 below.

Deodorizing effect on ammonia according to Test Example 2 (unit: ppm) hour blank test Example 1 Example 2 Comparative Example 1 initial concentration 100 100 100 100 0.5 hour 100 12 5 42 1 hours 100 7 3 25 2 hours 100 5 2 15 4 hours 100 4 less than 1 8 6 hours 100 3 less than 1 5

Deodorizing effect on trimethylamine according to Test Example 2 (unit: ppm) hour blank test Example 1 Example 2 Comparative Example 1 initial concentration 30 30 30 30 0.5 hour 30 7 5 14 1 hours 29 5 2 10 2 hours 28 3 less than 1 5 4 hours 28 less than 1 less than 1 3 6 hours 28 less than 1 less than 1 3

As shown in Tables 2 and 3, it was confirmed that Examples 1 and 2 according to the present invention had excellent deodorizing effects on ammonia and trimethylamine compared to Comparative Example 1.

(Test Example 3)

The samples of Examples 1, 2 and Comparative Example 1 were mixed in a commercially available dog shampoo in a weight ratio of 100:2, respectively, to prepare a dog shampoo for testing.

And after selecting 30 adult men and women raising dogs, and dividing them into three groups of 10 people each, the shampoo mixed with Example 1 for group 1, shampoo mixed with Example 2 for group 2, and Comparative Example 1 for group 3 A mixed shampoo was provided. And they were allowed to use it once a week for a month.

After one month, the degree of improvement in the dog's odor was evaluated using a 9-point scoring method (9: very improved, 7: slightly improved, 5: moderate, 3: slightly worse, 1: very worse), and the results are shown in Table 4 below. indicated.

Test Example 4 Results division Example 1 Example 2 Comparative Example 1 degree of odor improvement 7.2 8.1 6.0

As can be seen in Table 4, it was confirmed that Examples 1 and 2 according to the present invention significantly improved the degree of smell of dogs compared to Comparative Example 1.

The above description of the present invention is for illustration, and those of ordinary skill in the art to which the present invention pertains can understand that it can be easily modified into other specific forms without changing the technical spirit or essential features of the present invention. will be. Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive. For example, each component described as a single type may be implemented in a dispersed form, and likewise components described as distributed may be implemented in a combined form.

The scope of the present invention is indicated by the following claims, and all changes or modifications derived from the meaning and scope of the claims and their equivalents should be construed as being included in the scope of the present invention.

Claims (4)

A step of preparing raw materials including quince, mulberry bark, hwangryeon, cinnamon, baekduong, cypress, arborvitae and eoseongcho;
mixing and fermenting the raw material with EM stock solution, molasses, sea salt and water;
Ultrasonic extraction of the fermented raw material;
Plasma treatment of the ultrasonically extracted extract;
Distilling the plasma-treated extract and extracting;
Method for producing a composition for removing Demodex and odor of companion animals, characterized in that it comprises the step of filtering the distilled extract.
According to claim 1,
The plasma treatment is
After adding tourmaline and germanium to the ultrasonically extracted extract, the method for producing a composition for removing Demodex and odor in companion animals, characterized in that the plasma treatment is performed under a platinum catalyst.
According to claim 1,
The raw material is a method for producing a composition for removing Demodex and odors of companion animals, characterized in that it further comprises hairy dew, Gabija, and Ukriin.
A composition for removing Demodex and odor of companion animals, characterized in that it is prepared by the method of any one of claims 1 to 3.

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