JPS6344055Y2 - - Google Patents

Description

[Detailed Description of the Invention] (Industrial Field of Application) The present invention relates to improvements in the coupler openings of artificial kidneys, plasma separation devices, and other hollow fiber body fluid processing devices.

(Prior Art) As a body fluid treatment device such as an artificial kidney or a plasma separation device, a system is known in which a hollow fiber membrane is used to remove a target substance from the body fluid flowing through the membrane to the outside of the membrane.

FIG. 2 shows an example of an artificial kidney, in which a large number of hollow fiber membranes 31 are housed in a bundle inside a casing 30, and both ends of the hollow fiber membranes 31 are secured with a fixing material 32 such as polyurethane. casing 30
Blood guide ports 33 are fixed to the upper and lower ends of the casing 30 by rings 34 . Further, a coupler port 35 for guiding the dialysate is formed on the side of the casing 30.

When manufacturing such an artificial kidney, generally, a bundle of hollow fiber membranes 31 is first housed in a casing 30, sealing caps are attached to both ends of the casing 30, and viscous polyurethane is injected from each coupler port 35. inject. Next, the polyurethane is moved toward both ends of the casing by centrifugation, and after natural solidification, the sealing cap is removed,
The end face of the solidified polyurethane is cut to open each hollow fiber membrane, and finally each blood guide port 33 is attached to the casing 30 by a ring 34.

(Problems to be Solved by the Invention) However, as shown in detail in FIG. Since the draft angle of the mold is approximately 0.31 to 0.62 towards the end of the mold, when polyurethane is injected from the coupler port and centrifuged, polyurethane leaks from the coupler port 35 due to centrifugal force, staining the casing, etc. The dirt may adhere to the inner surface of the coupler port 35, and it is troublesome to remove this dirt. Also,
The proper amount of polyurethane could not be injected, and the hollow fiber membrane 3
There were problems such as 1 could not be fixed securely.

The present invention was proposed as a result of studies to solve these problems.

(Means for Solving the Problems) In the present invention, as shown in FIG. Fixing material 3
In the body fluid treatment device fixed to the casing, the coupler opening 6 formed on the side of the casing 1 is moved in a direction opposite to the casing end with respect to the horizontal axis 8, that is, in a direction opposite to the centrifugal direction. It is intended to be tilted to

This inclination angle θ is preferably equal to or greater than the draft angle of the mold with respect to the horizontal axis 8, preferably 1 degree or more. Moreover, the upper limit is determined within a practical range. That is, if the inclination angle θ is too large, problems such as troublesome connection of the dialysate tube and the like and difficulty in injecting the fixing material 3 will occur.

(Function) When the fixing material 3 such as polyurethane is injected from the coupler port 6 and centrifuged, the fixing material 3 adhering to the inside of the coupler port 6 moves smoothly toward the inner end of the casing 1 due to the inclination of the coupler port 6. However, it does not remain on the inner surface of the coupler port 6.

(Example) FIG. 1 shows an example of the present invention. In the figure, 1 is a casing made of hard resin such as polypropylene or polycarbonate, and as in the past, this casing 1 houses a bundle of hollow fiber membranes 2 such as cellulose membranes and ethylene vinyl alcohol copolymer (EVA) membranes. There is. The end of the hollow fiber membrane 2 is fixed to the casing 1 with a fixing material 3 such as polyurethane, and a blood guide port 4 made of the same material as the casing 1 is connected to the ring 5 at the end of the casing 1. It is installed accordingly.

The coupler port 6 formed on the side of the casing 1 is inclined with respect to the horizontal axis 8 in a direction opposite to the end of the casing, and the angle of inclination θ is 1 degree in this embodiment.

Note that the inner surface of the coupler port 6 in this embodiment also has a slope of about 0.31 to 0.62, as in the conventional case.

Additionally, in FIG. 1, reference numeral 7 denotes a baffle plate for dispersing the dialysate introduced from the coupler port 6 in the inner circumferential direction of the casing.

The inventor used a casing with the shape of the coupler opening described above, housed a hollow fiber membrane inside according to the normal manufacturing process, then injected polyurethane through the coupler opening and performed centrifugal treatment. However, no leakage of polyurethane from the coupler opening or adhesion to the inner surface of the coupler opening was observed.

(Effects) As explained above, according to the present invention, the coupler port of the casing is tilted in a predetermined direction, so that the fixing material is injected from the coupler port and the hollow fiber membrane bundle inside the casing is fixed by centrifugation. When doing,
It is possible to prevent the fixing material from protruding from the coupler opening and staining the casing or from adhering to the inner surface of the coupler, and it is possible to save time and effort in cleaning these stains. Further, since an appropriate amount of the fixing material is contained in the casing, effects such as being able to reliably support the hollow fiber membrane bundle with a predetermined strength can be obtained.

[Brief explanation of the drawing]

Fig. 1 is a sectional view of the coupler opening for explaining an embodiment of the present invention, Fig. 2 is a partial sectional view of an artificial kidney showing a conventional example, and Fig. 3 is a sectional view of the coupler opening in Fig. 2. It is a diagram. In the figure, 1 is a casing, 2 is a hollow fiber membrane, 3 is a fixing material, 6 is a coupler port, and 8 is a horizontal axis.

Claims (1)

[Scope of claims for utility model registration] (1) A large number of hollow fiber membranes are housed in a casing,
In a body fluid treatment device in which the hollow fiber membrane is fixed to the casing by a fixing material that solidifies over time, the coupler opening formed on the side of the casing is moved in a direction opposite to the casing end with respect to the horizontal axis. A hollow fiber type body fluid treatment device characterized by being inclined at a tilt angle. (2) The device according to item 1, wherein the inclination angle of the coupler opening is greater than or equal to the draft angle of the mold with respect to the horizontal axis.