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JPS6471851A - Manufacture of n-acylated mercapto-alpha-amino acid - Google Patents

Manufacture of n-acylated mercapto-alpha-amino acid

Info

Publication number
JPS6471851A
JPS6471851A JP63203968A JP20396888A JPS6471851A JP S6471851 A JPS6471851 A JP S6471851A JP 63203968 A JP63203968 A JP 63203968A JP 20396888 A JP20396888 A JP 20396888A JP S6471851 A JPS6471851 A JP S6471851A
Authority
JP
Japan
Prior art keywords
alpha
mercapto
amino acid
acylated
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63203968A
Other languages
English (en)
Other versions
JPH0448779B2 (ja
Inventor
Kurimaa Hansuupeetaa
Dorautsu Kaaruhaintsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Publication of JPS6471851A publication Critical patent/JPS6471851A/ja
Publication of JPH0448779B2 publication Critical patent/JPH0448779B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/12—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
JP63203968A 1987-08-21 1988-08-18 Manufacture of n-acylated mercapto-alpha-amino acid Granted JPS6471851A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873727897 DE3727897A1 (de) 1987-08-21 1987-08-21 Verfahren zur herstellung von n-acylierten mercapto-(alpha)-aminosaeuren

Publications (2)

Publication Number Publication Date
JPS6471851A true JPS6471851A (en) 1989-03-16
JPH0448779B2 JPH0448779B2 (ja) 1992-08-07

Family

ID=6334185

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63203968A Granted JPS6471851A (en) 1987-08-21 1988-08-18 Manufacture of n-acylated mercapto-alpha-amino acid

Country Status (7)

Country Link
US (1) US4918223A (ja)
EP (1) EP0304778B1 (ja)
JP (1) JPS6471851A (ja)
AT (1) ATE68787T1 (ja)
DE (2) DE3727897A1 (ja)
ES (1) ES2026612T3 (ja)
GR (1) GR3002989T3 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010058730A1 (ja) * 2008-11-19 2010-05-27 ポーラ化成工業株式会社 シワ改善剤

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5678290A (en) * 1989-05-17 1990-12-18 Astra Aktiebolag Process for the n-monoacylation of cysteine
DE10045831A1 (de) * 2000-09-14 2002-04-04 Gruenenthal Gmbh Thio-Aminosäuren
ES2252310T3 (es) 2000-09-14 2006-05-16 Grunenthal Gmbh Beta-tioaminoacidos.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496416A (en) * 1946-03-22 1950-02-07 Merck & Co Inc N-acyl penicillamines and preparation thereof
US3184505A (en) * 1962-06-18 1965-05-18 Mead Johnson & Co Process for the n-monoacylation of cysteine
DE1493600A1 (de) * 1965-03-18 1969-05-22 Diamalt Ag Verfahren zur Herstellung von N-Acetylcystein
DE2345835C2 (de) * 1973-09-12 1982-05-19 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von N-Acetyl-DL-penicillamin
US4375555A (en) * 1979-09-21 1983-03-01 The United States Of America As Represented By The United States Department Of Energy Synthesis of alpha-amino acids
US4370493A (en) * 1979-09-21 1983-01-25 The United States Of America As Represented By The Secretary Of Energy Synthesis of alpha-amino acids
US4371705A (en) * 1979-09-21 1983-02-01 The United States Of America As Represented By The United States Department Of Energy Synthesis of alpha-amino acids
FR2503151A1 (fr) * 1981-04-02 1982-10-08 Morelle Jean Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010058730A1 (ja) * 2008-11-19 2010-05-27 ポーラ化成工業株式会社 シワ改善剤
JPWO2010058730A1 (ja) * 2008-11-19 2012-04-19 ポーラ化成工業株式会社 シワ改善剤
JP5746864B2 (ja) * 2008-11-19 2015-07-08 ポーラ化成工業株式会社 シワ改善剤

Also Published As

Publication number Publication date
DE3865779D1 (de) 1991-11-28
US4918223A (en) 1990-04-17
EP0304778B1 (de) 1991-10-23
DE3727897C2 (ja) 1991-10-10
JPH0448779B2 (ja) 1992-08-07
GR3002989T3 (en) 1993-01-25
DE3727897A1 (de) 1989-03-02
EP0304778A1 (de) 1989-03-01
ES2026612T3 (es) 1992-05-01
ATE68787T1 (de) 1991-11-15

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