JPS5671059A - 1-sulfonyloxy-5-hexyne derivative and its preparation - Google Patents
1-sulfonyloxy-5-hexyne derivative and its preparationInfo
- Publication number
- JPS5671059A JPS5671059A JP14770879A JP14770879A JPS5671059A JP S5671059 A JPS5671059 A JP S5671059A JP 14770879 A JP14770879 A JP 14770879A JP 14770879 A JP14770879 A JP 14770879A JP S5671059 A JPS5671059 A JP S5671059A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- hexyne
- compound
- sulfonyloxy
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:The titled compound of formula I (R is lower alkyl or aryl).
EXAMPLE: 1-p-Toluenesulfonyloxy-5-hexyne.
USE: A raw material for preparing pentoxifylline [chemical name: 1-(5'-oxohexyl)- 3,7-dimethylxanthine] useful as a vasodilator and an enhancer for hematocytolysis. The compound of formula I is capable of giving petoxifylline via 1-(5'-hexynyl)- 3,7-dimethylxanthine readily and in high yield.
PROCESS: 5-Hexyn-1-ol is reacted with a sulfonyl halide of formula II (X is halogen) in the presence of a base at -30W50°C to afford the compound of formula I. A tertiary amine, e.g. pyridine, is preferably used as the base.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14770879A JPS5671059A (en) | 1979-11-16 | 1979-11-16 | 1-sulfonyloxy-5-hexyne derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14770879A JPS5671059A (en) | 1979-11-16 | 1979-11-16 | 1-sulfonyloxy-5-hexyne derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5671059A true JPS5671059A (en) | 1981-06-13 |
Family
ID=15436422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14770879A Pending JPS5671059A (en) | 1979-11-16 | 1979-11-16 | 1-sulfonyloxy-5-hexyne derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5671059A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011096450A1 (en) * | 2010-02-03 | 2011-08-11 | 宇部興産株式会社 | Non-aqueous electrolytic solution, electrochemical element using same, and alkynyl compound used therefor |
-
1979
- 1979-11-16 JP JP14770879A patent/JPS5671059A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011096450A1 (en) * | 2010-02-03 | 2011-08-11 | 宇部興産株式会社 | Non-aqueous electrolytic solution, electrochemical element using same, and alkynyl compound used therefor |
CN102696142A (en) * | 2010-02-03 | 2012-09-26 | 宇部兴产株式会社 | Non-aqueous electrolytic solution, electrochemical element using same, and alkynyl compound used therefor |
JP5849705B2 (en) * | 2010-02-03 | 2016-02-03 | 宇部興産株式会社 | Non-aqueous electrolyte, electrochemical device using the same, and alkynyl compound used therefor |
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