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JPS5515419A - Novel oxabicyclo(3,2,1)-octane derivative and its preparation - Google Patents

Novel oxabicyclo(3,2,1)-octane derivative and its preparation

Info

Publication number
JPS5515419A
JPS5515419A JP8709578A JP8709578A JPS5515419A JP S5515419 A JPS5515419 A JP S5515419A JP 8709578 A JP8709578 A JP 8709578A JP 8709578 A JP8709578 A JP 8709578A JP S5515419 A JPS5515419 A JP S5515419A
Authority
JP
Japan
Prior art keywords
oxabicyclo
formula
novel
preparation
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8709578A
Other languages
Japanese (ja)
Inventor
Tetsuji Kametani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Priority to JP8709578A priority Critical patent/JPS5515419A/en
Publication of JPS5515419A publication Critical patent/JPS5515419A/en
Pending legal-status Critical Current

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

NEW MATERIAL:A compound of formula I: (X is halogen; R is H, or lower alkoxy group).
EXAMPLE: 4-Bromo-3,8-epoxy-7-keto-6-oxabicyclo[3,2,1] octane-2-methylcarbonyl-6'-methoxytryptamineamide.
USE: An intermediate for the synthesis of the reserpine useful as a hypotensive drug.
PROCESS: A compound of formula II is reacted with a tryptamine of formula III in the presence of a silver oxide in a solvent, e.g. dioxane, under reflux for several hours to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP8709578A 1978-07-19 1978-07-19 Novel oxabicyclo(3,2,1)-octane derivative and its preparation Pending JPS5515419A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8709578A JPS5515419A (en) 1978-07-19 1978-07-19 Novel oxabicyclo(3,2,1)-octane derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8709578A JPS5515419A (en) 1978-07-19 1978-07-19 Novel oxabicyclo(3,2,1)-octane derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5515419A true JPS5515419A (en) 1980-02-02

Family

ID=13905383

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8709578A Pending JPS5515419A (en) 1978-07-19 1978-07-19 Novel oxabicyclo(3,2,1)-octane derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5515419A (en)

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