JPS55160720A - Remedial composition for cancer and its remedial device - Google Patents
Remedial composition for cancer and its remedial deviceInfo
- Publication number
- JPS55160720A JPS55160720A JP6665179A JP6665179A JPS55160720A JP S55160720 A JPS55160720 A JP S55160720A JP 6665179 A JP6665179 A JP 6665179A JP 6665179 A JP6665179 A JP 6665179A JP S55160720 A JPS55160720 A JP S55160720A
- Authority
- JP
- Japan
- Prior art keywords
- particles
- cancer
- cancer cell
- remedial
- heatable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 7
- 201000011510 cancer Diseases 0.000 title abstract 7
- 230000000246 remedial effect Effects 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002245 particle Substances 0.000 abstract 5
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 230000005674 electromagnetic induction Effects 0.000 abstract 2
- 229920002307 Dextran Polymers 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical class [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 230000005672 electromagnetic field Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 235000014413 iron hydroxide Nutrition 0.000 abstract 1
- NCNCGGDMXMBVIA-UHFFFAOYSA-L iron(ii) hydroxide Chemical compound [OH-].[OH-].[Fe+2] NCNCGGDMXMBVIA-UHFFFAOYSA-L 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 abstract 1
- 229960004528 vincristine Drugs 0.000 abstract 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Magnetic Treatment Devices (AREA)
- Electrotherapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A remedial composition for cancer, capable of killing a cancer cell from the interior, by radio frequency heating, and comprising superfine particles which are heatable by electromagnetic induction and suspended in an aqueous solution.
CONSTITUTION: Particles of size 1μ or less, e.g. iron hydroxide or oxide, which are heatable by electromagnetic induction, are suspended in an aqueous solution, e.g. a solution of dextrose, dextran or a salt, to give a remedial composition for cancer by intravenous injection. A cancer cell investigation agent, e.g. radioisotope or specific antibody against canncer, and a chemotherapeutic agent, e.g. 5-Fu, Actionmycin D or Vincristine, may be incorporated in the particles. After injection into a patient, the particles are heated by applying an alternating electromagnetic field, and the temperature rise of a cancer cell is finely adjusted to 8.0W9.5°C. Only the cancer cell is selectively killed by heated particles taken in the cell.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6665179A JPS55160720A (en) | 1979-05-29 | 1979-05-29 | Remedial composition for cancer and its remedial device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6665179A JPS55160720A (en) | 1979-05-29 | 1979-05-29 | Remedial composition for cancer and its remedial device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55160720A true JPS55160720A (en) | 1980-12-13 |
Family
ID=13322007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6665179A Pending JPS55160720A (en) | 1979-05-29 | 1979-05-29 | Remedial composition for cancer and its remedial device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55160720A (en) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59218164A (en) * | 1983-05-25 | 1984-12-08 | 林原 健 | Apparatus for increasing piercing amount of magnetic force line pulse |
| JPS60255728A (en) * | 1984-05-31 | 1985-12-17 | Mochida Pharmaceut Co Ltd | Preparation of magnetic vesicle composition for carcinostatic use |
| JPS615009A (en) * | 1984-05-31 | 1986-01-10 | Mochida Pharmaceut Co Ltd | Carcinostatic magnetic vesicular material composition |
| JPS61128983A (en) * | 1984-11-27 | 1986-06-17 | 大山 國賀 | Fixing of fine powder in living body for definite period andheating of the same to arbitrary temperature |
| JPS61265153A (en) * | 1985-05-21 | 1986-11-22 | 高木 征一 | Induction heater for warming treatment |
| JPS62266034A (en) * | 1986-05-14 | 1987-11-18 | 住友ベークライト株式会社 | Temperature sensor |
| US4735796A (en) * | 1983-12-08 | 1988-04-05 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| JPS6412545U (en) * | 1987-07-13 | 1989-01-23 | ||
| WO1990001939A1 (en) * | 1988-08-19 | 1990-03-08 | Meito Sangyo Kabushiki Kaisha | Agent for thermotherapy |
| JPH02134169A (en) * | 1988-11-16 | 1990-05-23 | Noboru Yoshimura | Cancer treatment device |
| US5043101A (en) * | 1983-02-08 | 1991-08-27 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| CN1047525C (en) * | 1993-03-13 | 1999-12-22 | 刘同乐 | Anticarcinogen containing copper and iron compound |
| WO2004016316A1 (en) * | 2002-08-16 | 2004-02-26 | Admetec Co., Ltd. | Heating method and heating apparatus therefor |
| WO2005120638A1 (en) * | 2004-06-09 | 2005-12-22 | Jochen Kalbe | Combination of radio waves and pharmacologically active substances |
| DE102004028156A1 (en) * | 2004-06-09 | 2006-01-05 | Kalbe, Jochen, Dr. | Combination of radio waves and one or more of monoclonal antibodies, tyrosine-kinase inhibitors, angiogenesisi inhibitors, farnesyl transferase inhibitors, topoisomerase - I or II inhibitors, cytokine and antisense oligonucleotides |
| JP2007267875A (en) * | 2006-03-30 | 2007-10-18 | Nano Therapy Kenkyusho:Kk | Body warming device |
| WO2009088062A1 (en) * | 2008-01-10 | 2009-07-16 | Akita University | Temperature measuring method and temperature control method using temperature sensitive magnetic body |
| US8214053B2 (en) | 2006-08-29 | 2012-07-03 | Nanotherapy Co., Ltd. | Body heating device |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5511509A (en) * | 1978-07-07 | 1980-01-26 | Toomasu Gorudon Robaato | Cancer therapy |
-
1979
- 1979-05-29 JP JP6665179A patent/JPS55160720A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5511509A (en) * | 1978-07-07 | 1980-01-26 | Toomasu Gorudon Robaato | Cancer therapy |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043101A (en) * | 1983-02-08 | 1991-08-27 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| JPS59218164A (en) * | 1983-05-25 | 1984-12-08 | 林原 健 | Apparatus for increasing piercing amount of magnetic force line pulse |
| US4735796A (en) * | 1983-12-08 | 1988-04-05 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| JPS60255728A (en) * | 1984-05-31 | 1985-12-17 | Mochida Pharmaceut Co Ltd | Preparation of magnetic vesicle composition for carcinostatic use |
| JPS615009A (en) * | 1984-05-31 | 1986-01-10 | Mochida Pharmaceut Co Ltd | Carcinostatic magnetic vesicular material composition |
| JPS61128983A (en) * | 1984-11-27 | 1986-06-17 | 大山 國賀 | Fixing of fine powder in living body for definite period andheating of the same to arbitrary temperature |
| JPH031988B2 (en) * | 1985-05-21 | 1991-01-11 | Seiichi Takagi | |
| JPS61265153A (en) * | 1985-05-21 | 1986-11-22 | 高木 征一 | Induction heater for warming treatment |
| JPS62266034A (en) * | 1986-05-14 | 1987-11-18 | 住友ベークライト株式会社 | Temperature sensor |
| JPS6412545U (en) * | 1987-07-13 | 1989-01-23 | ||
| WO1990001939A1 (en) * | 1988-08-19 | 1990-03-08 | Meito Sangyo Kabushiki Kaisha | Agent for thermotherapy |
| JPH02134169A (en) * | 1988-11-16 | 1990-05-23 | Noboru Yoshimura | Cancer treatment device |
| CN1047525C (en) * | 1993-03-13 | 1999-12-22 | 刘同乐 | Anticarcinogen containing copper and iron compound |
| WO2004016316A1 (en) * | 2002-08-16 | 2004-02-26 | Admetec Co., Ltd. | Heating method and heating apparatus therefor |
| WO2005120638A1 (en) * | 2004-06-09 | 2005-12-22 | Jochen Kalbe | Combination of radio waves and pharmacologically active substances |
| DE102004028156A1 (en) * | 2004-06-09 | 2006-01-05 | Kalbe, Jochen, Dr. | Combination of radio waves and one or more of monoclonal antibodies, tyrosine-kinase inhibitors, angiogenesisi inhibitors, farnesyl transferase inhibitors, topoisomerase - I or II inhibitors, cytokine and antisense oligonucleotides |
| JP2007267875A (en) * | 2006-03-30 | 2007-10-18 | Nano Therapy Kenkyusho:Kk | Body warming device |
| US8214053B2 (en) | 2006-08-29 | 2012-07-03 | Nanotherapy Co., Ltd. | Body heating device |
| WO2009088062A1 (en) * | 2008-01-10 | 2009-07-16 | Akita University | Temperature measuring method and temperature control method using temperature sensitive magnetic body |
| JP5263894B2 (en) * | 2008-01-10 | 2013-08-14 | 国立大学法人秋田大学 | Temperature measurement method and temperature control method using temperature-sensitive magnetic material |
| US8801280B2 (en) | 2008-01-10 | 2014-08-12 | Akita University | Temperature measuring method using temperature-sensitive magnetic substance and temperature controlling method |
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