JPH09295930A - Cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin cosmetic having sufficient antiaging action, not irritating skin, excellent in safety and effective in prevention and decrease of crease. SOLUTION: This cosmetic contains alpha hydroxylic acid (hereinafter referred to as AHA) or/and its salts and a peptide protein. Glycolic acid, lactic acid, malic acid or tararic acid or a mixture of several kinds of these compound is used as AHA used in this time and sodium salt, potassium salt or aluminum salt or a mixture of several kinds of these salts is used as the salt of AHA. A blend amount of the AHA or its salt is 0.01wt.% to 20wt.% based on total amount of the cosmetic. A hydrolyzed collagen is used as the peptide protein and a blend amount of the collagen is preferably 0.001 to 20wt.% based on total amount of the cosmetic.

Description

Detailed Description of the Invention

[0001]

OBJECT OF THE INVENTION It is an object of the present invention to provide an AHA-containing skin cosmetic having a sufficient anti-aging effect, not irritating the skin unlike conventional cosmetics, and excellent in safety.

[0002]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention reduces the transient irritation caused by alpha hydroxy acid (hereinafter referred to as AHA), and contains AHA, which is effective in preventing and reducing wrinkles. It is about fees.

[0003]

2. Description of the Related Art Wrinkles on the skin caused by aging, exposure to sunlight, etc. are considered to be caused by insufficient water content and reduced skin elasticity. AHA is in the spotlight as an anti-aging skin care ingredient that exfoliates excess calluses on the skin, resulting in less wrinkles and improving dry skin. However, it has been a problem that AHA gives skin irritation due to various factors such as skin quality or excessive addition amount. To alleviate this skin irritation, AH
At present, only measures such as limiting the amount of A added are taken, and for that reason, there are many problems such as not blending a sufficient amount for anti-aging action,
Improvement was desired.

[0004]

[Means for Solving the Problems] In order to achieve the above-mentioned object, the inventors of the present invention have conducted earnest studies to obtain a substance that is capable of alleviating transient irritation from among substances having excellent safety. As a result, they have found that these problems can be solved by blending a peptide protein with AHA or / and a salt of AHA, and have completed the present invention based on the above findings.

That is, the present invention provides a cosmetic for skin, which contains AHA and / or a salt of AHA and a peptide protein. Hereinafter, the configuration of the present invention will be described in detail. The alpha hydroxy acids such as glycolic acid, lactic acid, citric acid, malic acid, tartaric acid, etc. used in the present invention are organic acids having a hydroxyl group at the α-position, and ichthyosis and keratosis due to thickening of the horny layer, etc. It was mainly applied in the medical aspect of the treatment of. Among these AHA, glycolic acid having the smallest molecular weight is suitable from the viewpoint of absorption effect, but citric acid, lactic acid, malic acid, tartaric acid, or a mixture thereof may be used.

The AHA salts used in the present invention include sodium salt, potassium salt, ammonium salt and the like. The amount of AHA or a salt thereof added to the skin cosmetic of the present invention is not limited, but considering the effect of AHA on the skin, 0.01 wt% to 20 wt% is preferable in the total amount of the skin cosmetic, It is more preferably 0.1% by weight to 10% by weight.

Examples of the peptide protein used in the present invention include hydrolyzed collagen and the like. Proteins such as collagen fibers are composed of amino acids bound by peptide bonds, and those that are partly hydrolyzed into amino acids are called peptide proteins.

The blending amount of the peptide protein is not particularly limited, but is preferably 0.001% by weight to 20% by weight in the total amount of the skin cosmetics. If it is less than 0.001% by weight, the effect of alleviating transient irritation, which is the effect of the present invention, cannot be obtained. Further, even if it is added in an amount of 20% by weight or more, there is no great difference in the effect. The skin cosmetics of the present invention, in addition to the above-mentioned essential components, within the range that does not impair the effects of the present invention as necessary, cosmetics, quasi-drugs, various components commonly used in pharmaceuticals, aqueous components, Moisturizer, thickener, UV absorber,
An antiseptic, an antioxidant, a fragrance, a coloring agent, a drug, a crude drug, etc. are mixed. Of course, these must be used under qualitative and quantitative conditions that do not impair the object of the present invention.

The cosmetic composition for skin of the present invention may have any dosage form, for example, a solubilizing system such as lotion, an emulsifying system such as emulsion or cream or an ointment, a powder dispersion system, a water-oil two-layer system, water. −
Any dosage form such as oil-powder trilayer system may be used.

[0010]

EXAMPLES Next, the present invention will be specifically described with reference to Examples and Comparative Examples. Note that the present invention is not limited by this. The blending amount is% by weight. A cream having the following composition was produced and examined for its transient irritation alleviating effect. The blended AHA, AHA salt and peptide protein used were those listed in Table 1 below. Manufacturing methods (1), (2), and (3) were mixed and dissolved by heating, maintained at 78 ° C, and heated to 78 ° C (4), (5), (6),
Add to the mixture of (7) and (8) with stirring. The mixture was cooled with stirring with a homomixer to obtain a cream.

{Comparative Example 1} {Comparative Example 2} The same formulation except that the peptide protein was removed from the formulation of Example {Example 1} {Comparative Example 1} No salt was included in the aqueous solution of the AHA mixture {Example 2} {Comparative Example 2} The degree of neutralization of the salt in the aqueous solution of the AHA mixture is 62 to 69 mol%.

Correspondence table in Examples and Comparative Examples of mixture of AHA and peptide protein

[Table 1] <Stimulation relaxation test method> Example 1 with 7 or more healthy subjects
~ 2 and the creams of Comparative Examples 1-2 were used. That is, Examples 1 and 2 and Comparative Examples 1 and 2 were sequentially applied to the backs of both hands, and subjects were subjected to sensory evaluation for transient stimuli. The results are shown in Table 2.

Actual use test result (stimulus sensitivity)

[Table 2] As is clear from the results in Table 2, the products of the present invention of Examples 1 and 2 exhibited a superior effect of alleviating transient irritation as compared with those of Comparative Examples 1 and 2. {Example 3} Emulsion (1) Polyoxyethylene cetyl ether 5.5 (2) Paraoxybenzoic acid ester 0.2 (3) Squalane 15.0 (4) 1.3-Butylene glycol 4.5 (5) Water Degraded collagen 0.14 (6) Glycolic acid / ammonium glycolate mixture aqueous solution 5.0 (7) Purified water Residual total 100.0 Manufacturing method The emulsion of the present invention was obtained by a conventional method. The emulsion of the present invention had an excellent effect in alleviating transient irritation. {Example 4} Beauty serum (1) Hydroxyethyl cellulose 0.6 (2) 1.3-butylene glycol 9.4 (3) Paraoxybenzoic acid ester 0.1 (4) Polyoxyethylene sorbitan monooleate 0.1 (5) Hydrolyzed Collagen 0.14 (6) Glycolic Acid / Ammonium Glycolate Mixture Aqueous Solution 5.0 (7) Purified Water Residual Total 100.0 Manufacturing Method The cosmetic solution of the present invention was obtained by a conventional method. The beauty essence of the present invention had an excellent effect in alleviating transient irritation.

[0014]

EFFECTS OF THE INVENTION The cosmetic composition of the present invention can be felt by applying a peptide protein in an AHA-containing cosmetic composition, which is an active ingredient for reducing wrinkles due to aging, etc. It is epoch-making in that it can greatly alleviate transient irritation and brings excellent safety.

Claims (6)

[Claims] 1. A cosmetic containing an alpha hydroxy acid or / and a salt thereof and a peptide protein. 2. A cosmetic comprising an alpha hydroxy acid and a peptide protein. 3. A cosmetic comprising a salt of alpha hydroxy acid and a peptide protein. 4. The cosmetic according to claim 1, wherein the alpha hydroxy acid is a mixture of several kinds of glycolic acid, lactic acid, citric acid, malic acid and tartaric acid, or any one of them alone. 5. The cosmetic composition according to claim 1, wherein the salt of alpha hydroxy acid is a mixture of several kinds of sodium salt, potassium salt and ammonium salt, or any one of them alone. 6. The cosmetic composition according to claim 1, wherein the peptide protein is hydrolyzed collagen.