JP4641231B2 - Toothpaste composition - Google Patents

Description

  The present invention relates to a dentifrice composition containing erythritol.

  In general, the purpose of brushing teeth is to clean the mouth and obtain a refreshing feeling. A fragrance ingredient represented by menthol, which is usually included in a toothpaste composition, is indispensable for imparting a refreshing feeling, but in recent years, there has been a tendency to increase the number of oily meals and meals using spices. Therefore, a toothpaste composition having a higher refreshing feeling is desired.

  As a means to improve the refreshing feeling, there are methods such as increasing the blending amount of perfume ingredients or adding a solvent component such as ethanol. However, increasing the blending amount of these ingredients increases the irritation in the oral cavity. Moreover, since foaming is suppressed, there arises a problem that the feeling of use when polished is impaired.

  Therefore, a toothpaste composition that obtains a higher refreshing feeling without increasing the blending amount of a fragrance component or a solvent such as ethanol is desired.

Patent Document 1 discloses a toothpaste composition having an excellent refreshing feeling, which contains a component that causes an endothermic hydration reaction such as erythritol and has a water content of 10% by mass or less. However, because the water content is low, the water-soluble polymer compounded as a binder does not dissolve sufficiently, and over time, moisture and other liquid components can be seen to bleed out of the system. There was a problem with sex. Moreover, although a cool feeling was obtained, it did not reach a clear cool feeling in the oral cavity.
JP 2000-191383 A

  An object of the present invention is to provide a toothpaste composition containing erythritol having a higher refreshing feeling and excellent storage stability and immediate effect of cooling feeling.

The present invention includes the following components (A), (B) and (C):
(A) Erythritol having a particle size of less than 45 μm 15 to 60% by mass
(B) Water 15-30% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition containing
The present invention also includes the following components (A), (B) and (C):
(A) Erythritol having a particle diameter of less than 45 μm 20 to 60% by mass
(B) Water 15-30% by mass
(C) Binder 0.6-3 mass%
Is a toothpaste composition.

  The toothpaste composition according to the present invention is excellent in storage stability and, when applied to the oral cavity, provides an immediate cooling feeling without increasing the blending amount of fragrance ingredients and solvents such as ethanol, etc. can get.

The dentifrice composition of the present invention is characterized by containing erythritol (component (A)) having a particle size of less than 45 μm. Normally available erythritol is crystalline erythritol obtained by recrystallizing after fermenting glucose, and its particle size is larger than that of the product of the present invention. Therefore, it is preferable to use what obtained the erythritol grind | pulverized and adjusted the particle diameter for the toothbrushing composition of this invention.
A roller mill, hammer mill, high-speed pulverizer, pulverizer, etc. are generally used to pulverize erythritol, but a high-speed pulverizer and hammer mill that are easy to adjust the particle size and excellent in production efficiency. Is preferred.
The structure of erythritol includes three isomers of L-erythritol, D-erythritol, and meso-erythritol, and the present invention may have any of these structures. As crystalline erythritol, commercially available products such as those manufactured by Nikken Chemical Co., Ltd., Mitsubishi Chemical Foods Co., Ltd., and Celestor are available.

In the toothpaste composition of the present invention, the content of erythritol having a particle size of less than 45 μm is 15 to 60% by mass, more preferably 20 to 55% by mass, and even more preferably 25 to 50% from the viewpoints of refreshing feeling and cooling feeling. % By mass, most preferably 30-50% by mass.
For this reason, the blending amount of erythritol having a particle size of less than 45 μm is 20 to 60% by mass, more preferably 25 to 55% by mass, even more preferably 30 to 50% by mass, and most preferably from the viewpoints of coolness and coolness. It is 35-50 mass%.

  The particle size of erythritol used in the present invention is less than 45 μm from the viewpoint of instantly dissolving in the oral cavity and instantly obtaining a cool feeling, preferably 3 μm or more and less than 45 μm, more preferably 5 μm or more and less than 45 μm. is there. In addition, when the erythritol particle diameter exceeds 45 μm, it does not dissolve instantaneously in the oral cavity but gradually melts, so that it is difficult to obtain an immediate cool feeling.

The erythritol particle size is measured as follows.
Sieve: JIS standard sieve φ75mm
Aperture: 500 μm, 355 μm, 250 μm, 180 μm, 125 from the top
The receiver is located under a sieve with openings of μm, 90 μm and 45 μm.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on 500 μm sieve and classify with electromagnetic vibrator for 5 minutes.
The erythritol that passes through the 45 μm sieve and is present on the receiver is erythritol having a particle diameter of less than 45 μm.
The particle size distribution and average particle size of less than 45 μm can be measured with a dry laser distribution diffraction type particle size distribution measuring device.

  In the toothpaste composition of the present invention, the content of water (component (B)) is preferably 15% by mass or more from the viewpoint of storage stability, and is preferably 30% by mass or less from the viewpoint of obtaining a high refreshing feeling and cooling feeling. . More preferably, it is 15-25 mass%. If it is less than 15% by mass, it is difficult to dissolve the binder, and the stability is lowered.

The binder used in the present invention (Component (C)), is not particularly limited, sodium alginate, sodium carboxymethyl cellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethyl cellulose, hydroxy sheet cellulose, pectin, tragacanth gum, Use one or more water-soluble polymers selected from gum arabic, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, psyllium seed gum, polyvinyl alcohol, sodium chondroitin sulfate, methoxyethylene maleic anhydride copolymer It is preferable to do this.
In the toothpaste composition of the present invention, the content of the binder is from 0.6 to 3% by mass, more preferably from 0.7 to 2% by mass, and even more preferably from the viewpoint of storage stability. It is -1.2 mass%. If it is less than 0.6% by mass, the stability is not sufficient, while if it exceeds 3% by mass, the viscosity of the composition becomes high and the refreshing feeling is impaired.

  In the toothpaste composition of the present invention, in addition to the above components, for example, foaming agent, foaming aid, abrasive, wetting agent, sweetener, preservative, enzyme, pH adjuster, bactericidal agent, medicinal component, pigment, dye, A fragrance | flavor etc. can be contained suitably. Moreover, you may contain the erythritol with a particle diameter of 45 micrometers or more. In this case, the average particle size of erythritol contained in the composition or the average particle size of erythritol to be blended is preferably 200 μm or less, more preferably 10 to 150 μm. When the average particle size is 45 μm or more, the sieving rate (cumulative amount) is plotted on regular established paper, and the value corresponding to 50% is adopted, and when it is less than 45 μm, dry laser distribution diffraction particle size distribution measurement Use the value of the device.

  As abrasives, silica-based abrasives such as precipitated silica, silica gel, aluminosilicate, zirconosilicate; dicalcium phosphate dihydrate and anhydrous, calcium pyrophosphate, calcium carbonate, alumina, aluminum hydroxide, acetic acid Magnesium, tribasic magnesium phosphate, zeolite, synthetic resin-based abrasive and the like are preferably used.

As the wetting agent, glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltite, lactit, trehalose and the like are preferably used.
Furthermore, examples of the sweetening agent include saccharin sodium, aspartame, thaumatin, acesulfame potassium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perilartin.

  As a fragrance, 1-menthol, carvone, anethole, eugenol, limonene, peppermint oil, spearmint oil, ocimen, n-amyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronole acetate, cineol, linalool, Examples include ethyl linalool, crocodile, thymol, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, perilla oil, clove oil, and eucalyptus oil.

  As other various active ingredients, water-soluble phosphate compounds such as potassium salt and sodium salt of orthophosphoric acid; allantochlorohydroxyaluminum, azulene, glycyrrhetinic acid, epidihydrocholesterin, α-bisabolol, glycyrrhizic acid and the like Anti-inflammatory agents such as salts; phenolic compounds such as hinokitiol; antiplasmin agents such as tranexamic acid and epsilon aminocaproic acid; vitamin Es of dl-tocopherol acetate; copper compounds such as copper chlorophyllin sodium and copper gluconate; sodium chloride; Salts such as potassium nitrate; bactericides such as quaternary ammonium compounds such as triclosan, cetylpyridinium chloride, benzethonium chloride, chlorhexidine salts, trichlorocarbanilide; dextranase, mutanase, amylase, chloride Enzymes such as lysozyme; extracts such as sugarcane, duck, clove, rosemary, hornon, safflower; aluminum lactate, strontium chloride, berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, polyvinylpyrrolidone, dihydrocholesterol, citric acid Zinc etc. are mentioned.

  In the toothpaste composition of the present invention, it is desirable that erythritol is dispersed in a powder state from the viewpoint of obtaining a higher refreshing feeling. For this purpose, erythritol is preferably added as a powder to the final production process. By using such a production method, erythritol can be present in a powder state in the toothpaste composition without being substantially dissolved in water. Specifically, for example, after measuring the prescribed amount of each component such as purified water, wetting agent, binder, flavoring agent, preservative, abrasive, foaming agent, sweetener, and medicinal component, it is according to certain production conditions. The toothpaste composition of the present invention can be produced by mixing and fully swelling the binder, and further adding a polishing agent, a foaming agent, a flavoring agent, and powdered erythritol and defoaming and mixing.

  The toothpaste composition of the present invention has a viscosity at 25 ° C. (helicus type viscometer, rotor C, 2.5 r / min, 1 minute) of 1500 to 5000 dPa · s, further 2000 to 4500 dPa · s, particularly 2500 to 4000 dPa · s. Is preferred.

<Preparation of toothpaste composition>
According to the composition shown in Table 1, toothpaste compositions of Examples 1 to 3 and Comparative Examples 1 to 3 were prepared.
Erythritol was added last.

(1) Evaluation of refreshing feeling Ten subjects (5 males and 5 females) took 1 g of a toothbrushing composition on a toothbrush, brushed freely for about 2 minutes, and refreshed after rinsing. Evaluation was made according to the following criteria. In addition, the result of the determination shown in each table shows the highest evaluation among 10 people.
<Evaluation criteria for coolness>
◎: Strong feeling in mouth ○: Refreshing feeling in mouth is slightly strong ×: Feeling in mouth is weak

(2) Evaluation of storage stability The toothpaste composition shown in Table 1 was packed in a toothpaste tube for storage and stored at 5 ° C, room temperature, and 40 ° C for 3 months. Thereafter, the tube was opened and whether or not the liquid component was separated from the toothpaste composition was evaluated according to the following criteria.
<Evaluation criteria for storage stability>
◎: No liquid separation is observed ○: Liquid separation is slightly observed ×: Liquid separation is clearly observed

(3) Immediate evaluation of cool feeling Ten subjects (5 men, 5 women) took 1 g of a toothbrushing composition on a toothbrush, brushed freely for about 2 minutes, and used the toothpaste composition of Comparative Example 1 as a reference. The coolness was evaluated according to the following criteria.
<Evaluation criteria for immediate effect of coolness>
◎: Cooling feeling is more immediate than standard toothpaste composition ○: Cooling feeling is more immediate than standard toothpaste composition ×: Cooling feeling is equal to or less than that of standard toothpaste composition Is

  As shown in Table 1, the toothpaste compositions of Examples 1 to 3 contained a large amount of erythritol having a particle size of less than 45 μm, and thus were excellent in immediate effect of cooling feeling. Furthermore, the toothpaste compositions of Examples 2 and 3 contained more erythritol having a particle size of less than 45 μm, and thus were more excellent in quick cooling effect. Moreover, since it contained 15-30 mass% of moisture and 0.6-3 mass% of binder, it was excellent in long-term storage stability.

  On the other hand, although the toothpaste composition of Comparative Example 1 contains a large amount of erythritol having a particle size of 45 μm or more and less than 355 μm, it does not contain much erythritol having a particle size of less than 45 μm. The result was inferior to ~ 3. Further, the toothpaste composition of Comparative Example 3 contained a large amount of erythritol having a particle size of 355 μm or more and less than 1000 μm, but it did not feel a cool feeling because it did not contain much erythritol having a particle size of less than 355 μm. Further, the toothpaste compositions of Comparative Examples 2 and 3 had poor storage stability due to low water content and low binder content.

Claims (3)

The following components (A), (B) and (C):
(A) Erythritol having a particle size of less than 45 μm 15 to 60% by mass
(B) Water 15-30% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition comprising: The following components (A), (B) and (C):
(A) Erythritol having a particle diameter of less than 45 μm 20 to 60% by mass
(B) Water 15-30% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition. Component (C) is sodium alginate, sodium carboxymethyl cellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethyl cellulose, hydroxy sheet cellulose, pectin, tragacanth gum, arabic gum, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, The dentifrice composition according to claim 1 or 2, which is one or more binders selected from the group consisting of psyllium seed gum, polyvinyl alcohol, sodium chondroitin sulfate, and a methoxyethylene maleic anhydride copolymer.