JP4555094B2 - Medical container - Google Patents

Description

  The present invention relates to a medical container including a communication member that controls discharge of a drug such as an infusion.

The medical container is provided with a cylindrical body that has a closed tip and can be opened. Examples of the cylindrical body include a discharge port used at the time of administration of a drug solution and a drug container that stores a drug added to the drug solution in the medical container.
Prior to infusion of the patient, mix and dissolve drugs that are difficult to pre-mix into the infusion, such as vitamins and antibiotics, in a vial or soft bag containing the infusion. The preparation of chemicals has been done. In order to prepare such a chemical solution aseptically and with a simple operation, a drug container containing a drug mixed with the chemical solution is attached to a soft bag containing the chemical solution, and the drug container is infused during infusion. There has been proposed a medical container in which a drug container and a soft bag are communicated to mix a drug and a drug solution by bending and breaking the provided weak part through a soft bag.

As such a medical container, a chemical solution container is disclosed in JP-A-2003-62038 (Patent Document 1).
As shown in FIG. 1 of Japanese Patent Application Laid-Open No. 2003-62038, this chemical solution container 1 includes storage chambers 13a and 13b separated by a partition wall 12 that can be communicated, and a chemical solution storage sachet suspended in one storage chamber 13a. In the chemical solution container 10 with a chemical solution containing sachet 20 provided with 20, an easily peelable seal portion is provided on at least a part of the peripheral portion 31 of the chemical solution containing sachet 20, A strong seal portion 26 is formed between the wall surfaces 11 and 11b of the storage chamber 13a. Further, the weak seal portion 25 is formed by being connected to the strong seal portion 26 and bonding both wall surfaces of the storage chamber 13a. The seal strength of the partition wall 12 is set so as to be stronger than the seal strength of the cleavage portion 23 and the weak seal portion 25 and weaker than the seal strength of the strong seal portion 26.
JP 2003-62038 A

With such a configuration, the chemical solution container 1 can reliably open the chemical solution storage pouch 10 in conjunction with the pressing of the storage chamber 13a, and the opening operation of the chemical solution storage pouch 10 is easy. Moreover, according to this medicine container 1, when the storage chamber 13a is pressed and the partition wall is cleaved, not only the chemical solutions (other storage fluids) in the storage chambers 13a and 13b are mixed, but also the cleavage. Interlocking with the weak seal part and the easily peelable seal part can be realized, so that the opening of the chemical solution containing sachet can be easily and reliably realized. Therefore, it is possible to avoid a situation in which the drug solution is administered without forgetting to open the drug solution containing pouch.
However, there is a risk that the drug solution container 1 can perform drug administration before the partition wall 12 is opened to mix the drug solutions in the storage chambers 13a and 13b.
Therefore, the present invention achieves the above-described object, and provides a medical container that can prevent a drug from being administered before mixing the drugs and can easily prepare for drug administration.

What achieves the above object is as follows.
(1) A soft bag divided into a first drug chamber and a second drug chamber by a partition weak seal part from which an internal space can be peeled, and a first drug stored in the first drug chamber A second medicine housed in the second medicine chamber, a discharge port attached so as to communicate with the first medicine chamber, an inside of the soft bag and a discharge port attached to the soft bag A medical container comprising a communication inhibiting member for inhibiting communication, wherein the communication inhibiting member narrows the periphery of the discharge port from one surface and the other surface of the soft bag. A narrow pressure portion for inhibiting communication between the bag and the discharge port, and a narrow pressure state holding portion for holding a narrow pressure state by the narrow pressure portion,
Further, the narrow pressure portion includes a first narrow pressure portion and a second narrow pressure portion for narrowing the periphery of the discharge port from one surface and the other surface of the soft bag, The state holding portion is a connecting portion that connects the first narrow pressure portion and the second narrow pressure portion in a state where the narrow pressure state is held, and the connecting portion is the first narrow pressure portion. And a fitting portion provided in the second narrow pressure portion, and the connecting portion includes an insertion path provided in the first narrow pressure portion, and the second insertable in the insertion path. A pin provided in the narrow pressure portion; the first narrow pressure portion and the second narrow pressure portion are closed; and the pin is inserted into the insertion path to be fitted to the first narrow pressure portion. are those parts with narrow pressure state by said second narrow pressure section is maintained, further, the narrow pressure state by a narrow pressure part, the first drug chamber or the second Followed peeling simultaneously to or the release of the partitioning weak seal portion by the pressing of the medicament compartment, wherein the spread of soft bag, between the first of said narrow pressure section second narrow pressure portion is widened, the A medical container that is released when a pin comes out of the insertion path .
(2) The communication-inhibiting member includes an enveloping portion that encapsulates a connection portion side of the discharge port with the soft bag, and two connecting portions are provided so as to face each other through the encapsulating portion. The medical container as described in (1).
(3) The unsealing strength of the communication inhibiting member when the first medicine chamber or the second medicine chamber is pressed is greater than the peel strength of the partition weak seal portion (1) or ( The medical container as described in 2).
( 4 ) The communication inhibition member includes an inhibition portion that covers the periphery of the discharge port so as to inhibit external insertion of the discharge port into the discharge port. The communication inhibition member includes the first At the same time as or after the peeling of the weak seal portion for partition by pressing of the drug chamber or the second drug chamber, the narrow pressure portion is pushed and expanded by spreading of the soft bag, and the pin is inserted into the insertion path the medical container according to any one of in which (1) do not become removable from the flexible bag by passing from (3).

( 5 ) A soft bag divided into a first drug chamber and a second drug chamber by a partition weak seal part from which the internal space can be peeled, and a first drug stored in the first drug chamber, A second medicine housed in the second medicine chamber, a discharge port attached to communicate with the first medicine chamber, and an exterior to the discharge port of the discharge port attached to the soft bag A discharge inhibiting member for hindering insertion from the container, the discharge inhibiting member sandwiching the periphery of the discharge port from one surface side and the other surface side of the soft bag A pinch part, a pinch state holding part for holding the pinch state of the soft bag by the pinch part, and an obstruction that covers the periphery of the discharge port so as to prevent external insertion into the discharge port of the discharge port With
The pinching portion includes a first pinching portion and a second pinching portion for pinching the periphery of the discharge port from one surface side and the other surface side of the soft bag, and the pinching state holding portion includes: A connecting portion that connects the first sandwiching portion and the second sandwiching portion while maintaining the sandwiched state, and the connecting portion is provided in the first sandwiching portion and the second sandwiching portion. The connecting portion includes an insertion path provided in the first pinching portion and a pin provided in the second pinching portion that can be inserted into the insertion path, By closing the first sandwiching portion and the second sandwiching portion and inserting the pin into the insertion path and fitting, the sandwiched state between the first sandwiching portion and the second sandwiching portion is maintained. a shall further state sandwiched by the pinching state holding unit, the first drug chamber or the second Followed peeling simultaneously to or the release of the partitioning weak seal portion by the pressing of the agent chamber, by the spread of the soft bag, pushed open between said first pinching portion said second pinching portion is the pin A medical container which is released by being removed from the insertion path , and the blocking member is removable from the soft bag.
(6) The discharge inhibiting member includes a storage portion that stores the discharge port, and the two connection portions are provided so as to face each other via the storage portion. .
(7) The unsealing strength of the discharge inhibiting member when the first medicine chamber or the second medicine chamber is pressed is larger than the peel strength of the partition weak seal portion (5) or ( The medical container as described in 6).
(8) the connecting portion, the one in which connecting by said first nip by the spread of the soft bag and the second pinching portion is widened is released (5) to (7) The medical container in any one .

( 9 ) The medical container according to any one of (5) to (8) , wherein the soft bag includes a weak seal portion for inhibiting communication between the first drug chamber and the discharge port. .
(10) wherein the partitioning weak seal portion, any of the first weak seal, to be that (1) no includes a hard second weak seal portion separated from the first weak seal part (9) A medical container according to 1.
( 11 ) The medical container according to any one of (1) to (10), wherein the blocking member can be attached to a hole provided in the vicinity of the discharge port of the soft bag.
( 12 ) The discharge port is made of a hard or semi-rigid material, and has a cylindrical portion whose front end portion is closed and whose rear end portion is sealed so as to be inserted, and provided at least at the front end portion of the cylindrical portion. A first stress applying portion that is provided so as to sandwich the breakable portion that is formed and the breakable portion of the cylindrical portion, and is fixed to one inner surface of the first drug chamber, and the first drug chamber A second stress applying part that is fixed to the other inner surface, and the breakable part is ruptured by spreading between the first stress applying part and the second stress applying part, and the cylindrical part The medical container according to any one of (1) to (11) .
( 13 ) The medical container according to (12) , wherein a third medicine is accommodated in the cylindrical portion of the discharge port.

  According to the medical container of the present invention, the medicine is administered before mixing the first medicine housed in the first medicine chamber and the second medicine housed in the second medicine chamber. It can be prevented, and preparation for drug administration is easy.

Hereinafter, the medical container of the present invention will be described in detail with reference to the accompanying drawings.
1 is a front view of a medical container according to an embodiment of the present invention, FIG. 2 is a cross-sectional view taken along line AA of the medical container shown in FIG. 1, and FIG. 3 is a cross-sectional view of the medical container shown in FIG. 4 is a front view of the communication inhibiting member used, FIG. 4 is a side view of the communication inhibiting member shown in FIG. 3, FIG. 5 is a development view of the communication inhibiting member shown in FIG. 3, and FIG. It is explanatory drawing for demonstrating the usage method of a medical container.
The medical container 1 of the present invention includes a soft bag 2 divided into a first drug chamber 3 and a second drug chamber 4 by a partition weak seal portion 12 from which an internal space can be peeled, and a first drug chamber A container body comprising a first medicine 5 housed in 3, a second medicine 6 housed in a second medicine chamber 4, and a discharge port 7 attached so as to communicate with the first medicine chamber 3 10 and a communication inhibiting member 14 which is attached to the soft bag 2 of the container body 10 and inhibits the communication between the inside of the soft bag 2 and the discharge port 7. The communication-inhibiting member 14 narrows the pressure around the discharge port 7 from one surface and the other surface of the soft bag 2 and restricts communication between the soft bag 2 and the discharge port 7. A narrow pressure state holding portion 17 for holding a narrow pressure state by the narrow pressure portions 15 and 16, and the narrow pressure state by the narrow pressure portions 15 and 16 is the first drug chamber 3 or the second drug chamber. The narrow pressure portions 15 and 16 are released by the spread of the soft bag 2 simultaneously with or following the separation of the partition weak seal portion 12 by the pressing of 4.

The communication inhibiting member 14 of this embodiment inhibits only the communication between the inside of the soft bag 2 and the discharge port 7, and does not inhibit the external insertion of the discharge port 7 into the discharge port 7d.
As shown in FIG. 1, the medical container 1 of the present invention includes a container main body 10 and a communication inhibiting member 14 attached to the container main body 10.
In the medical container 1 of this embodiment, as shown in FIG. 1, the container body 10 includes a soft bag 2 having a first drug chamber 3 and a second drug chamber 4 by a weak seal portion 12 for partitioning, A first medicine 5 housed in the first medicine chamber 3, a second medicine 6 housed in the second medicine chamber 4, and a discharge port 7 attached to the lower end 22 of the soft bag 2; And the mixed injection port 11 attached to the upper end 24 of the soft bag 2. And the member 14 for communication inhibition attached to the lower end part 22 of the soft bag 2 is provided.

As shown in FIG. 1, the soft bag 2 in this embodiment includes a partition weak seal portion 12, a first drug chamber 3 divided by the partition weak seal portion 12, and a second drug chamber 4. I have.
As shown in FIG. 1, an upper end side seal portion 24 and a lower end side seal portion 22 are provided at the upper end portion and the lower end portion of the flexible bag 2. The upper end side seal portion 24 and the lower end side seal portion 22 are wide seal portions. The upper end side seal portion 24 is provided with a mixed injection port attachment portion 9 for attaching the mixed injection port 11, and the lower end side seal portion 24 is formed with a discharge port attachment portion 8 for attaching the discharge port 7. Yes. The mixed injection port attachment portion 9 and the discharge port attachment portion 8 are formed by not sealing a part of the upper end side seal portion 24 and the lower end side seal portion 22.
As shown in FIG. 1, the soft bag 2 is partitioned by a partition weak seal portion 12. In the embodiment of the present invention, the partition weak seal portion 12 is provided so as to cross the entire lateral direction of the drug chamber of the soft bag 2 as shown in FIG. The partition weak seal portion 12 is formed by fusing the sheet material of the soft bag 2 in a band shape.
The partition weak seal portion 12 of the embodiment is peeled off when the first drug chamber 3 or the second drug chamber 4 is strongly pressed (when squeezed), and is separated from the first drug chamber 3 and the second drug chamber. 4 can be communicated. Moreover, the weak seal part 12 for partition of this invention peels simultaneously with the opening of the member 14 for communication inhibition, or before it, when the 1st chemical | medical agent chamber 3 or the 2nd chemical | medical agent chamber 4 is pressed. .

The sealing strength of the partition weak seal portion 12 is preferably such that it does not peel off due to the pressure applied to the soft bag 2 during transportation but peels when the soft bag 2 is strongly pressed with a finger or the like. The partition weak seal portion 12 is preferably formed by fusing the soft bag 2. The fusion is preferably thermal fusion, high frequency fusion or the like. Since the soft bag 2 has the two drug chambers 3 and 4 divided into the partition weak seal portion 12 in this way, drugs of different components can be mixed aseptically in the soft bag 2. it can. Further, in the embodiment shown in FIG. 1, the partition weak seal portion 12 is provided in a straight line horizontally with respect to the soft bag 2, but is not limited thereto. Moreover, it is preferable that the strong seal part 13 which cannot peel substantially is formed in the both ends of the weak seal part 12 for a partition.
The seal strength (initial peel strength) of the partition weak seal portion 12 is preferably 0.5 to 10 N / 10 mm, and particularly preferably 2 to 6 N / 10 mm. If the seal strength is within this range, the weak seal part of the partition weak seal part 12 will not be accidentally peeled off during transportation or storage, and the work of peeling off the partition weak seal part 12 is easy. .

The volume ratio between the first drug chamber 3 and the second drug chamber 4 divided by the partition weak seal portion 12 is preferably 1: 1 to 1:20. In particular, the volume ratio is 1: It is preferable that it is 1-1: 5.
The volume of the first drug chamber 3 of the medical container 1 should be as small as possible. If it is such a structure, when the 2nd chemical | medical agent chamber 4 is pressed, it will become easy to open the weak seal part 12 for a partition and the member 14 for communication inhibition by one action.
Specifically, the volume of the first drug chamber 3 is preferably about 20 to 3000 ml, and particularly preferably 50 to 2000 ml. Moreover, it is preferable that the volume of the 2nd chemical | medical agent chamber 4 is about 20-3000 ml, and 50-2000 ml is especially preferable.

  The second drug chamber 4 of the medical container 1 preferably has a larger volume and liquid volume than the first drug chamber 3. By doing in this way, when the 2nd chemical | medical agent chamber 4 is pressed, the stress to the member 14 for communication inhibition becomes large, and the member 14 for communication inhibition is opened reliably. Further, the amount of fluid to be filled [including the medicine and the head space (gas)] is the total volume of the medical container (in the state where the partition weak seal 12 is peeled off or the communication blocking member 14 is opened to form one chamber). The effect of the present invention becomes more prominent when the content is 20 to 50% by weight. In medical containers such as infusion bags, other drugs are co-injected. For this reason, it is bag-made in the medical container in anticipation of a reserve capacity of the same amount to several times the amount of fluid to be filled. The amount of fluid in the medical container having the partition weak seal portion is 20 to 50% by volume. However, even with such a small fluid filling amount, according to the present invention, the stress on the communication inhibiting member 14 is increased. It is easy to start and the partition weak seal part 12 and the communication inhibiting member 14 can be reliably opened by a single opening operation.

  The soft bag 2 is a soft synthetic resin having a certain degree of heat resistance, such as polyolefin (for example, a mixture containing polyolefin such as polyethylene, polypropylene, polybutadiene, ethylene-propylene copolymer, a mixture of polypropylene and polyethylene or polybutene), and these Partially cross-linked product, ethylene-vinyl acetate copolymer (EVA), polyester (polyethylene terephthalate, polybutylene terephthalate, etc.), soft vinyl chloride resin, polyvinyl acetate, polyvinylidene chloride, silicone, polyurethane, polyamide elastomer, polyester elastomer, Various thermoplastic elastomers such as styrene elastomers such as styrene / ethylene / butylene / styrene copolymer or any combination of these ( Resin, polymer alloy, laminate, etc.), a resin layer of a hard material such as polyethylene terephthalate, polyester such as polyethylene naphthalate, polyamide such as nylon, and the above-mentioned soft material (for example, , Polyethylene) resin layers are used. By being formed of these soft resins, the soft bag 2 is inflated, whereby the partition weak seal portion 12 and the communication blocking member 14 can be easily opened.

  A preferred soft resin material is soft polyvinyl chloride. This soft polyvinyl chloride has heat resistance that can withstand the high temperatures of autoclave sterilization, and is excellent in handleability because of its high flexibility. Furthermore, there is an advantage that the fixing to the soft bag 2 can be easily performed and fixed by fusion of the discharge port 7 and the manufacturing cost can be reduced. Moreover, as a suitable constituent material of the soft bag 2, the soft resin which blended the polypropylene and the styrene-butadiene copolymer can be mentioned. This material is preferable in that it is excellent in water resistance, heat resistance, flexibility and processability. The thickness of the sheet material which comprises the soft bag 2 is not specifically limited, For example, in the case of the sheet material made from a soft polyvinyl chloride, it is preferable that it is about 20-500 micrometers. As the soft bag 2, it is desirable to use an extruded film or a blown tube having a tensile elastic modulus of 500 MPa or less, preferably 50 to 300 MPa.

The soft bag 2 is produced by blow molding using the above resin, the one formed by fusing the peripheral portions of the two sheets formed by the resin, and the one piece formed by the resin. Any of the one formed by folding the sheet and fusing the peripheral edge portion, or the one formed by extrusion molding using the above resin and fusing the peripheral edge of the opening may be used. The one sheet or the other sheet constituting the soft bag 2 in the present invention is either the front side sheet or the back side sheet constituting the soft bag 2.
In the drug chambers 3 and 4 of the soft bag 2, infusion agents (chemical solutions) 5 and 6 are stored. The drug chambers 3 and 4 preferably contain different components. As such an infusion, for example, two or more solutions such as peritoneal dialysis solution, transcentral vein infusion, transperipheral vein infusion, transperipheral vein injection, liquid nutrient, etc. Those that need to be mixed are preferred. Examples of the infusion include physiological saline, electrolyte solution, Ringer's solution, high calorie infusion, glucose solution, water for injection, amino acid electrolyte solution, and the like, but are not limited thereto. For example, the glucose electrolyte solution is stored in one of the drug rooms, the amino acid solution is stored in the other, and the stability of water-soluble vitamins such as vitamin B1, vitamin B2, vitamin B6, vitamin C, panthenol, and nicotinamide in both chambers. Can be appropriately sorted and stored. In this case, a vitamin-containing high-calorie total infusion solution can be obtained by storing a liquid preparation mainly composed of fat-soluble vitamins such as vitamin A, vitamin D, vitamin E, and vitamin K in a drug container attached to a drug room described later. .

Moreover, the upper end side seal part 24 of the soft bag 2 is provided with a hole 24a (hanging part) for hanging on a hanger or the like. Further, a hole 23 for attaching the communication inhibiting member 14 is formed in the lower end side seal portion 22.
Furthermore, in order to maintain the quality of the chemical solution, a film such as an aluminum foil may be laminated on the soft bag 2 in order to impart oxygen barrier properties, light shielding properties, and the like. Further, a thin film such as a vapor deposition film made of an oxide such as titanium oxide, aluminum oxide, or silicon oxide may be formed on the surface of the soft bag 2 in order to impart oxygen barrier properties. Or you may provide the resin film which has these thin films as an intermediate | middle layer.
As shown in FIG. 1, it is preferable to use a known port as the discharge port 7. For example, it is preferable that the discharge port 7 includes a cylindrical port member and a seal member that seals the opening and can be inserted through the needle tube. Specifically, the port is preferably composed of a cylindrical member 7a having both ends opened and a lid portion 7b having a seal member 7c that seals the opening on one end of the cylindrical member 7a. With such a configuration, first, the chemical solution can be injected through the cylindrical member 7 a attached to the soft bag 2.

Moreover, it is preferable that the sealing member has a self-occlusion property, and after the needle tube is extracted from the elastic body, the puncture hole is blocked to prevent the chemical liquid from leaking. Examples of the constituent material of the sealing material include polyolefins such as polyethylene, polypropylene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, and cross-linked ethylene-vinyl acetate copolymer, polyester, polyvinyl chloride, polyurethane, Flexible polymer materials such as polyamide, thermoplastic resins such as polyamide elastomer and polyester elastomer (thermoplastic elastomer), natural rubber, isoprene rubber, silicone rubber, butadiene rubber, various rubber materials such as styrene-butadiene rubber, etc. An elastic material or a combination of any two or more of these materials can be used, and those containing an elastic material are preferable from the viewpoint of sealing performance and resealability. Moreover, as a port, it is preferable that it is a molded article of a cylindrical shape or an elliptical cylinder shape. The constituent material of the discharge port 7 is preferably the same as that of the drug container.
As shown in FIG. 1, it is preferable to use a well-known port for the mixed injection port 11. For example, it is preferable to include a cylindrical port member and a seal member that seals the opening and can be inserted through the needle tube. Specifically, the port preferably has the same configuration as that of the discharge port 7, and includes a cylindrical member 11a having both ends opened and a seal member 11c for sealing the opening on one end of the cylindrical member 11a. It is preferable that it consists of the cover part 11b. With such a configuration, first, the chemical solution can be injected through the cylindrical member 11 a attached to the soft bag 2.

Communicating inhibiting member 14, as shown in FIGS. 3-5, it is provided with a narrow pressure section 15, and a narrow pressure state holding section 17. The inhibition portion of the communication inhibiting member 14 of this embodiment inhibits the communication between the discharge port 7 and the soft bag 2 as shown in FIGS. 3 to 5.
With such a configuration, the medical container 1 of the present invention mixes the first medicine 5 accommodated in the first medicine chamber 3 and the second medicine 6 accommodated in the second medicine chamber 4. Drug administration can be prevented before preparation for drug administration can be easily performed.
The narrow pressure portions 15 and 16 include a first narrow pressure portion 15 and a second narrow pressure portion 16 for sandwiching the periphery of the discharge port 7 from one surface and the other surface of the flexible bag 2. .
As shown in FIGS. 2 to 5, the first narrow pressure portion 15 and the second narrow pressure portion 16 include enveloping portions 15 a and 16 a that encapsulate the connection portion side of the flexible bag 2 of the discharge port 7. ing. And the opening end of the 1st narrow pressure part 15 and the 2nd narrow pressure part 16 is the narrow pressure end part 15b which presses the soft bag 2 around the discharge port 7 at a level that substantially impedes liquid flow, The narrow pressure end portion 16b is formed.

The envelope portions 15a and 16a of the first narrow pressure portion 15 and the second narrow pressure portion 16 of the embodiment can be accommodated except for the base end portion of the discharge port 7 (the cylindrical portion of the discharge port). Can only accommodate.). The first narrow pressure portion 15 and the second narrow pressure portion 16 have substantially the same configuration.
In the embodiment, each of the first narrow pressure portion 15 and the second narrow pressure portion 16 is a semi-cylindrical portion having a reduced diameter at the distal end and an opening at the proximal end. Inside the semi-cylindrical portion, as shown in FIGS. 4 and 5, enveloping portions 15 a and 16 a for partially storing the discharge port 7 are provided. The first narrow pressure portion 15 and the second narrow pressure portion 16 have the same configuration. The openings of the semi-cylindrical parts are narrow pressure end parts 15b and 16b. The end surface shapes of the narrow pressure end portions 15b and 16b may be flat surfaces, chamfered end surfaces, and hemispherical or semielliptical cross sections. In order to prevent damage to the soft bag 2, it is preferable that the end face shape of the narrow pressure end portions 15b and 16b has no edge, and the chamfered end face and the cross section are hemispherical or semi-elliptical. Is preferable. In the embodiment of the present invention, in the state where the first narrow pressure portion 15 and the second narrow pressure portion 16 sandwich the soft bag 2, the narrow pressure end portion 15 a and the narrow pressure end portion 16 a are arranged around the discharge port 7. The sheet is continuously adhered to form the partition portion 25. Further, in this embodiment, the narrow pressure end portions 15b and 16b are preferably formed so that the portion that narrows the pressure around the discharge port 7 has a substantially semi-elliptical shape or a semi-circular shape.

Further, the communication inhibiting member 14 is preferably attachable to a hole 23 provided in the vicinity of the discharge port 7 of the flexible bag 2 as in the embodiment shown in FIG. The embodiment of the present invention can be attached to the lower end side seal portion 22 of the soft bag 2 by passing the pin 20 of the holding portion 17 through the hole 23 and connecting the holding portions 17 to each other.
The narrow pressure state holding portion 17 is a connecting portion that connects the first narrow pressure portion 15 and the second narrow pressure portion 16 in a state where the narrow pressure portions 15 and 16 are held in a narrow pressure state. The first narrow pressure portion 15 and the second narrow pressure portion 16 are pushed and spread by the spread of the soft bag 2 so that the connection between the first narrow pressure portion 15 and the second narrow pressure portion 16 is released. It is preferable that it is a thing.
The connecting portion 17 is a fitting portion provided in the first narrow pressure portion 15 and the second narrow pressure portion 16. Specifically, the connecting portion 17 can be inserted into an insertion path (an insertion hole in the embodiment) 18 provided in the first narrow pressure portion 15 and the insertion path 18, and the first narrow pressure portion 15 and the second narrow pressure portion 15. An insertion means (in the embodiment, a pin) 20 for holding the narrow pressure state of the narrow pressure portion 16 is provided. The outer diameter of the pin 20 is almost the same as the inner diameter of the hole 18. 2 and 4, the first narrow pressure portion 15 and the second narrow pressure portion 16 are closed, and the pin 20 is inserted through the insertion hole 18 to be fitted. The narrow pressure state of the first narrow pressure portion 15 and the second narrow pressure portion 16 is maintained. Further, as shown in FIG. 6, the narrow pressure state is released by the pin 20 coming out of the insertion hole 18 due to the expansion of the first medicine chamber 3. The connecting portion may be an engaging portion.

  When the communication inhibiting member 14 is attached to the soft bag 2 so as to enclose the attachment portion of the discharge port 7 to the soft bag 2 and the predetermined region of the soft bag 2 slightly above the attachment portion, FIG. As shown, the narrow pressure surfaces 15b, 16b of the first narrow pressure portion 15 and the second narrow pressure portion 16 surround the upper part of the opening on the first drug chamber side 3 side of the soft bag 2 of the discharge port 7. When the soft bag 2 is pressed from one side and the other side, the partition portion 25 is formed in a semi-elliptical shape around the discharge port 7. In the partition 25, a fourth drug chamber 26 independent of the first drug chamber 3 is formed. The fourth drug chamber 26 is preferably not filled with a chemical solution, but may be filled with a small amount. With the configuration as described above, the first drug chamber 3 and the discharge port are formed by the partition portion 25 because the first drug 5 in the first drug chamber 3 hardly flows into the discharge port 7 side. Communication with 7 can be inhibited. For this reason, it can prevent administering a chemical | medical solution before mixing the chemical | medical agent in the soft bag 2. FIG.

  The constituent material of the communication inhibiting member 14 is preferably a hard or semi-hard material. Furthermore, it is desirable to be transparent. Specifically, polyolefins such as rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, polystyrene, polycarbonate, ABS resin, acrylic resin, polymethyl methacrylate (PMMA), polyacetal, polyarylate, polyacrylonitrile, polyethylene terephthalate (PET), Examples thereof include polyesters such as polybutylene terephthalate (PBT), butadiene-styrene copolymers, various resins such as aromatic or aliphatic polyamides, and combinations of these arbitrarily. Among these, hard polyvinyl chloride, polyethylene, polypropylene, and polyester are preferable because they are highly safe and have excellent adhesion to the soft bag 2.

As shown in FIG. 6, the narrow pressure state by the narrow pressure portions 15 and 16 is simultaneous with or subsequent to the separation of the partition weak seal portion 12 due to the pressing of the first drug chamber 3 and the second drug chamber 4. The narrow pressure portions 15 and 16 are released by being spread by the spread of the soft bag 2. When the first medicine chamber 3 or the second medicine chamber 4 is pressed, the communication inhibiting member 14 is less likely to be opened than the partition weak seal portion 12. Specifically, the opening strength of the communication inhibiting member 14 is preferably greater than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. .
Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the communication inhibiting member 14 in this order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the openable strength of the communication inhibiting member 14 is 2. To 14N, in particular 5 to 10N.

  Further, like the communication inhibiting member 14 shown in FIGS. 39 and 40, the narrow pressure state release assisting portions 15c and 16c may be provided. The narrow pressure state release assisting portions 15c and 16c extend from the envelope portions 15a and 16a to the distal end side of the communication inhibiting member 14 (the partition weak seal portion side when attached to the soft bag 2). This is a portion that contacts a sheet forming one drug chamber 3. As shown in FIG. 40, the narrow pressure state release assisting portions 15c and 16c are formed in a flat plate shape and extend obliquely outward from the vicinity of the inner end portions of the enveloping portions 15a and 16a facing each other. Yes. In addition, the narrow pressure state cancellation | release assistance part may be formed in the plate shape which curves, and also rod shape. And by providing such a narrow pressure state cancellation | release assistance part, the stress by the expansion of the soft bag 2 at the time of a medical container being pressed can be received reliably. Further, the force when the soft bag 2 spreads is prevented from concentrating near the narrow pressure end portions 15b and 16b, and the narrow pressure end portion when the soft bag 2 spreads, that is, when the inhibiting member is released. Reduce the risk of bag damage near 15b and 16b.

Next, the manufacturing method of the medical container 1 of this invention is demonstrated using FIG. The method is not limited to this method.
First, a tube body formed of a soft synthetic resin is prepared. And the upper end side seal part 24 which has one partial unsealed part (mixed injection port attachment part 9) in this tube body, the lower end side seal part 22 which has one partial unsealed part (discharge port attachment part 8), The soft bag 2 is formed by forming the partition weak seal portion 12. Subsequently, the cylindrical member 7a of the discharge port 7 is inserted and fixed to the discharge port mounting portion 8 which is a partially unsealed portion of the lower end side seal portion 22, and is fixed to the first drug chamber 3 via the cylindrical member 7a. After the first medicine 5 is injected, the lid portion 7b is fixed to the cylindrical member 7a and sealed in a state where the container is fixed so that the cylindrical member 7a is located on the upper side.
Then, the cylindrical member 11a of the mixed injection port 11 is fixed to the partially unsealed portion of the upper end side seal portion 24, the second medicine 6 is injected through the cylindrical member 11a, and the cylindrical member 11a is positioned upward. In a state where the container is fixed, the cap member 11b having an elastic member attached to the cylindrical member 11a is fixed and sealed. After sterilization, the communication inhibiting member 14 is attached to the soft bag 2 in a state where the container is fixed so that the discharge port 7 faces upward, and the manufacture of the medical container 1 of the present invention is completed. A partition 25 is formed around the discharge port 7 by the communication inhibiting member 14, and communication between the first drug chamber 3 and the discharge port 7 is blocked by the partition 25.
In this way, a medical container filled with a medicine as shown in FIG. 1 is produced. The injection of the first drug 5 and the sealing operation of the first drug chamber 3 may be performed before the injection of the second drug 6 and the sealing operation of the second drug chamber.

Next, the usage method of the medical container 1 of this invention is demonstrated.
First, when the second drug chamber 4 of the medical container 1 is strongly pressed with fingers or the like, first, the partition weak seal portion 12 is broken, and then, as shown in FIG. Due to the inflow of the chemical solution, the first drug chamber 3 expands, the communication inhibiting member 14 is opened, and the drug chamber communicates with the discharge port 7. Then, the communication inhibiting member 14 is removed from the soft bag 2 and the insertion needle is inserted into the discharge port 7d of the discharge port 7 to perform drug administration.
Next, a medical container which is another embodiment of the present invention will be described. 7 is a front view of a medical container according to another embodiment of the present invention, FIG. 8 is a cross-sectional view taken along line BB of the medical container shown in FIG. 7, and FIG. 9 is a medical container shown in FIG. FIG. 10 is a side view of a discharge inhibiting member used in the medical container shown in FIG. 9, and FIG. 11 is a discharge inhibiting member used in the medical container shown in FIG. FIG. 12 is an explanatory view for explaining a method of using the medical container shown in FIG.

Since the medical container 30 is different from the medical container 1 only in the configuration of the discharge inhibiting member, the above is referred to for the same configuration.
The discharge inhibiting member 31 of this embodiment inhibits insertion of the discharge port 7 from the outside of the discharge port 7d.
The medical container 30 of the present invention includes a soft bag 2 divided into a first drug chamber 3 and a second drug chamber 4 by a partition weak seal portion 12 whose internal space can be peeled, and a first drug chamber. A container comprising a first medicine 5 housed in 3, a second medicine 6 housed in a second medicine chamber 4, and a discharge port 7 attached so as to communicate with the first medicine chamber 3 A main body 10 and a discharge inhibiting member 31 that is attached to the soft bag 2 of the container main body 10 and inhibits external insertion into the discharge port 7d of the discharge port 7 are provided. The discharge inhibiting member 31 holds the soft bag 2 sandwiched between the sandwiched portions 32 and 33 that sandwich the periphery of the discharge port 7 from one surface side and the other surface side of the soft bag 2 and the sandwiched portions 32 and 33. Pinching state holding portion 17 and hindering portions 32b and 33b that cover the discharge port 7d so as to hinder the external insertion of the discharge port 7 into the discharge port 7d. Simultaneously with or following the peeling of the weak seal portion 12 for partitioning by pressing the first drug chamber 3 or the second drug chamber 4, the pinching portions 32 and 33 are released by the spread of the soft bag 2 and released. The discharge inhibiting member 31 can be detached from the soft bag 2.

The discharge inhibiting member 31 of the present invention is attached by sandwiching the soft bag 2 with the sandwiching portions 32 and 33, and can be removed from the soft bag 2 by releasing the sandwiching state of the sandwiching portions 32 and 33. Yes.
The discharge inhibiting member 31 does not hinder the communication between the inside of the soft bag 2 and the discharge port 7 unlike the discharge inhibiting member 14, and is inserted from the outside into the discharge port 7d of the discharge port 7 (specifically, Only the needle tube of the infusion set) is inhibited.
As shown in FIGS. 9, 10, and 11, the discharge inhibiting member 31 includes a first sandwiching portion 32, a second sandwiching portion 33, a holding portion 17, and a hinge portion 19. The first sandwiching portion 32 and the second sandwiching portion 33 are connected by the hinge portion 19 to open and close. Since the holding unit 17 is as described above, the above description is referred to. In addition, you may not provide a hinge part.

The first sandwiching portion 32 and the second sandwiching portion 33 include housing portions 32 a and 33 a for housing the discharge port 7 and inhibition portions 32 b and 33 b. As shown in FIGS. 7 and 8, the first sandwiching portion 32 and the second sandwiching portion 33 accommodate the entire discharge port 7.
The distal end portions of the main body portions of the first sandwiching portion 32 and the second sandwiching portion 33 are reduced in diameter, and are semi-cylindrical portions having a bottom portion at the proximal end portion. Further, flat plate portions 32d and 33d are formed at the tip of the main body.
Specifically, the opening end portions of the front end portions of the main body portions of the first sandwiching portion 32 and the second sandwiching portion 33 are inclined outward toward the distal end. With such a configuration, the distal end side portions excluding the distal end portions of the first sandwiching portion 32 and the second sandwiching portion 33 are greatly separated from each other toward the distal end side. The flat plate portions 32 d and 33 d are portions that reliably receive stress due to the spread of the soft bag 2. The front end side portions of the first sandwiching portion 32 and the second sandwiching portion 33 are non-pressing portions that do not narrow the soft bag 2 in the sandwiched state.
In the Example of this invention, the base end part of the 1st clamping part 32 and the 2nd clamping part 33 is the inhibition parts 32b and 33b. Specifically, since a wall surface (bottom portion) is formed at the proximal end portions of the first sandwiching portion 32 and the second sandwiching portion 33, the needle tube cannot be inserted into the discharge port 7d from behind. In addition, the 1st clamping part and the 2nd clamping part should just cover the discharge port 7d vicinity of the discharge port 7 at least.

In addition, as shown in FIG. 12, the sandwiched state by the sandwiching portions 32 and 33 is simultaneous with or subsequent to the separation of the partition weak seal portion 12 due to the pressing of the first drug chamber 3 and the second drug chamber 4. The pinching portions 32 and 33 are pushed and spread by the spread of the soft bag 2 and released. When the first medicine chamber 3 or the second medicine chamber 4 is pressed, the discharge inhibiting member 31 may be more difficult to open than the partition weak seal portion 12. Specifically, the opening strength of the discharge inhibiting member 31 is preferably slightly higher than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. .
Moreover, when the 2nd chemical | medical agent chamber 4 is pressed, the weak seal part 12 for a partition and the member 31 for discharge | emission inhibition may be opened in order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the unsealing strength of the discharge inhibiting member 31 is It is preferably 2 to 14N, particularly 5 to 10N.

With the configuration as described above, when the second drug chamber 4 is pressed to peel off the weak seal portion 12 for partitioning and the drug solution is allowed to flow into the first drug chamber 3, the soft bag 2 spreads and the holding portion 17 is fitted. The combination is released and the discharge inhibiting member 31 can be detached from the soft bag 2. Then, after removing the discharge inhibiting member 31, the needle tube can be pierced through the discharge port 7d to perform drug administration.
With the above configuration, before mixing the drug, the discharge port 7d cannot be pierced from the outside, so that drug administration is prevented, and the discharge inhibiting member is opened by pressing the soft bag 2. Therefore, preparation for drug administration can be easily performed.

Next, a medical container which is another embodiment of the present invention will be described. 13 is a front view of a medical container according to another embodiment of the present invention, FIG. 14 is a cross-sectional view taken along line CC of the medical container shown in FIG. 13, and FIG. 15 is a medical container shown in FIG. FIG. 16 is a side view of the communication inhibiting member shown in FIG. 15, FIG. 17 is a development view of the communication inhibiting member shown in FIG. 15, and FIG. It is explanatory drawing for demonstrating the usage method of the medical container shown.
The medical container 35 of the present invention differs from the medical container 1 shown in FIG. 1 only in the configuration of the communication inhibiting member. The communication inhibiting member 36 of the medical container 35 is different from the communication inhibiting member 14 in that the communication inhibiting member 36 has an inhibition part for inhibiting insertion from the outside to the discharge port. Since the other points are as described above, the above description is referred to.

  The medical container 35 of the present invention includes a soft bag 2 divided into a first drug chamber 3 and a second drug chamber 4 by a partition weak seal portion 12 from which an internal space can be peeled, and a first drug chamber. 3, a first medicine 5 housed in 3, a second medicine 6 housed in the second medicine chamber 4, and a discharge port 7 attached so as to communicate with the first medicine chamber 3. A main body 10 and a communication inhibiting member 36 that is attached to the soft bag 2 of the container main body 10 and inhibits the communication between the inside of the soft bag 2 and the discharge port 7 are provided. The communication-inhibiting member 36 narrows the pressure around the discharge port 7 from one surface and the other surface of the soft bag 2 to restrict communication between the soft bag 2 and the discharge port 7. The narrow pressure state holding portion 17 for holding a narrow pressure state by the narrow pressure portions 37, 38 is provided, and the narrow pressure state by the narrow pressure portions 37, 38 is the first drug chamber 3 or the second drug chamber. The narrow pressure portions 37 and 38 are released by the spread of the soft bag 2 at the same time as or after the separation of the weak seal portion 12 for partitioning due to the pressing of 4 and the peeling.

Further, the communication blocking member 36 of the medical container 35 includes blocking portions 37d and 38d that cover the periphery of the discharge port 7d so as to block external insertion of the discharge port 7 into the discharge port 7d. In the member 36, the narrow pressure portions 37 and 38 are expanded by the spread of the soft bag 2 at the same time as or following the peeling of the partition weak seal portion 12 by the pressing of the first drug chamber 3 or the second drug chamber 4. It can be removed from the soft bag 2.
As shown in FIGS. 15 to 17, the communication inhibiting member 36 according to the embodiment of the present invention has both communication between the discharge port 7 and the inside of the soft bag 2 and insertion from the outside into the discharge port 7 d of the discharge port 7. It inhibits.
Communicating inhibiting member 36, as shown in FIGS. 15 to 17, a narrow pressure part 37, 38, a holding portion 17, and a hinge portion 19.
With such a configuration, the communication inhibiting member 36 can prevent drug administration before the drug is mixed, and can easily prepare for drug administration.

The narrow pressure portion includes a first narrow pressure portion 37 and a second narrow pressure portion 38 for sandwiching the periphery of the discharge port 7 from one surface and the other surface of the soft bag 2. The first narrow pressure part 37 and the second narrow pressure part 38 are connected by the hinge part 19 and can be opened and closed. In addition, you may not provide a hinge part. As shown in FIGS. 15 to 17, the first narrow pressure portion 37 and the second narrow pressure portion 38 include housing portions 37a and 38a for holding the discharge port 7, inhibitor portions 37d and 38d, and a soft bag. 2 is provided with narrow pressure surfaces 37b and 38b that hinder communication between the inside of the gas tank 2 and the discharge port 7.
The first narrow pressure portion 37 and the accommodating portions 37 a and 38 a of the second clip 38 accommodate the entire discharge port 7 in the embodiment. In addition, the accommodating portions 37a and 38a cover the periphery of the discharge port 7d so as to prevent external insertion. For this reason, the communication inhibiting member 36 shown in the embodiment inhibits the communication between the discharge port 7 and the inside of the soft bag 2 and inhibits the insertion of the discharge port 7 from the outside to the discharge port 7d.

  In the embodiment of the present invention, each of the first narrow pressure portion 37 and the second narrow pressure portion 38 is a semi-cylindrical portion having a reduced diameter at the distal end portion and a bottom portion at the proximal end portion. Inside the semi-cylindrical portion, as shown in FIGS. 16 and 17, accommodating portions 37a and 38a for accommodating the discharge port 7 are provided. The first narrow pressure portion 37 and the second narrow pressure portion 38 have the same configuration. By overlapping the first narrow pressure portion 37 and the second narrow pressure portion 38, the entire discharge port 7 can be accommodated inside. The openings of the semi-cylindrical parts are narrow pressure end parts 37b and 38b. The end surface shape of the narrow pressure end portions 37b and 38b may be any of a flat surface, a chamfered end surface, and a semi-spherical or semi-elliptical cross section. In order to prevent damage to the soft bag 2, it is preferable that the end face shape of the narrow pressure end portions 37b and 38b has no edge, and the chamfered end face and cross section are semicircular or semielliptical. Etc. are preferable. In the embodiment of the present invention, in the state where the first narrow pressure portion 37 and the second narrow pressure portion 38 sandwich the soft bag 2, the narrow pressure end portion 37 b and the narrow pressure end portion 38 b are arranged around the discharge port 7. The sheet is continuously adhered to form the partition portion 25. Further, in this embodiment, the narrow pressure end portions 37b and 38b are preferably formed so that the portion that narrows the pressure around the discharge port 7 is substantially semi-elliptical and semi-circular.

In the embodiment of the present invention, the base end portions (base end portions of the semi-cylindrical portions) of the first narrow pressure portion 37 and the second narrow pressure portion 38 are the inhibition portions 37d and 38d. Specifically, since a wall surface (bottom portion) is formed at the proximal end portions of the first narrow pressure portion 38 and the second narrow pressure portion 38, the needle tube cannot be inserted into the discharge port 7d from behind. . Note that the first Sema圧 portion second Sema圧 portion as long as it covers the vicinity of the discharge port 7d of at least the discharge port 7.
Further, the communication inhibiting member 36 can be attached to the hole 23 provided in the upper end portion (upper end side seal portion) 24 or the lower end portion (lower end side seal portion) 22 of the soft bag 2 as in the embodiment shown in FIG. It is preferable that The embodiment of the present invention can be attached to the lower end side seal portion 22 of the soft bag 2 by passing the pin 20 of the holding portion 17 through the hole 23 and fitting the holding portion 17.

The pinching state holding portion 17 is a connecting portion that connects the first narrow pressure portion 37 and the second narrow pressure portion 38 in a state where the pinching state of the narrow pressure portions 37 and 38 is held. The first narrow pressure portion 37 and the second narrow pressure portion 38 are pushed and spread by the spread of the soft bag 2 to release the connection between the first narrow pressure portion 37 and the second narrow pressure portion 38. Preferably there is.
The connecting portion 17 is preferably a fitting portion provided in the first narrow pressure portion 37 and the second narrow pressure portion 38. The connecting portion 17 can be inserted into the insertion path (insertion hole in the embodiment) 18 provided in the first narrow pressure portion 37 and the insertion path 18, and the first narrow pressure portion 37 and the second narrow pressure portion can be inserted. An insertion means (a pin in the embodiment) 20 for holding the narrow pressure state of the portion 38 is provided. The outer diameter of the pin 20 is almost the same as the inner diameter of the hole 18. With such a configuration, as shown in FIGS. 15 and 16, the first narrow pressure portion 37 and the second narrow pressure portion 38 are closed, and the pin 20 is inserted into the insertion hole 18 to be fitted. The narrow pressure state of the first narrow pressure portion 37 and the second narrow pressure portion 38 is maintained. In addition, as shown in FIG. 17, the pin 20 is removed from the insertion hole 18 due to the expansion of the first drug chamber 3 and the narrow pressure state is released. The connecting portion may be an engaging portion provided in the first narrow pressure portion and the second narrow pressure portion.

  In addition, the narrow pressure state by the narrow pressure portions 37 and 38 is simultaneously or simultaneously with the separation of the partition weak seal portion 12 due to the pressing of the first drug chamber 3 and the second drug chamber 4 as shown in FIG. Subsequently, the narrow pressure portions 37 and 38 are pushed and spread by the spread of the soft bag 2 and released. When the first drug chamber 3 or the second drug chamber 4 is pressed, the communication inhibiting member 36 is less likely to be opened than the partition weak seal portion 12. Specifically, the opening strength of the communication inhibiting member 36 is preferably greater than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. . Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the communication inhibiting member 36 in this order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the openable strength of the communication inhibiting member 14 is 2. To 14N, in particular 5 to 10N.

When the communication inhibiting member 36 is attached to the soft bag 2 so that the discharge port 7 is accommodated therein, the first narrow pressure portion 37 and the second narrow pressure portion 38 are narrowed as shown in FIGS. By pressing the flexible bag 2 from one surface and the other surface so that the pressure end portions 37 b and 38 b surround the discharge port 7, the partition portion 25 is formed around the discharge port 7 in a semi-elliptical shape. In the partition 25, a fourth drug chamber 26 independent of the first drug chamber 3 is formed. The fourth drug chamber 26 is preferably not filled with a chemical solution, but may be filled with a small amount. With the above configuration, the first drug chamber 3 and the discharge port are separated by the partition portion 25 because the first drug 5 in the first drug chamber 3 hardly flows into the discharge port 7 side. Communication with 7 can be inhibited. For this reason, it can prevent administering a chemical | medical solution before mixing the chemical | medical agent in the soft bag 2. FIG. The manufacturing method of the medical container 35 is preferably the same as that of the medical container 1.
Further, the communication inhibiting member 36 of this embodiment may also include the narrow pressure state release assisting portions 15c and 16c as in the communication inhibiting member 14 shown in FIGS. The narrow pressure state release assisting part is as described above.

Next, the usage method of the medical container 35 of this invention is demonstrated.
First, when the second drug chamber 4 of the medical container 35 is strongly pressed with fingers or the like, the partition weak seal portion 12 is first broken, and then, as shown in FIG. The first medicine chamber 3 is expanded by the inflow of the chemical solution, the communication inhibiting member 36 is opened, and the inside of the soft bag 2 and the discharge port 7 are communicated. Then, the communication inhibiting member 36 is removed from the soft bag 2 and the insertion needle is inserted into the discharge port 7d of the discharge port 7 to perform drug administration.

Next, a medical container 40 that is another embodiment of the present invention will be described.
19 is a front view of a medical container according to another embodiment of the present invention, FIG. 20 is a front view of a communication inhibiting member used in the medical container shown in FIG. 19, and FIG. 21 is a communication shown in FIG. FIG. 22 is a cross-sectional view of the inhibiting member, and FIG. 22 is an explanatory diagram for explaining a method of using the medical container shown in FIG.
The medical container 40 is different from the medical container 35 only in the configuration of the communication inhibiting member. Further, the communication inhibiting member 41 of the medical container 40 and the communication inhibiting member 36 of the medical container 35 differ only in the configuration of the holding portion and the configuration of the first narrow pressure portion.
The holding state holding part 42 is provided between the first narrow pressure part 43 and the second narrow pressure part 44 as shown in FIGS. A breakable portion that connects the narrow pressure portion 43 and the second narrow pressure portion 44 and is ruptured when the first narrow pressure portion 43 and the second narrow pressure portion 44 are expanded by the spread of the soft bag 2. It is.

As shown in FIGS. 20 and 21, the communication inhibiting member 41 of the present invention includes a first narrow pressure portion 43, a second narrow pressure portion 44, a breakable portion 42, and a hinge portion 19. Yes. In addition, you may not provide a hinge part. Since the second narrow pressure portion 44 is the same as the second narrow pressure portion 16 described above, the above description is referred to. The first narrow pressure portion 43 includes a distal end side portion 45 and a proximal end side portion 46. In this embodiment, the distal end side portion 45 and the proximal end side portion 46 are configured to be engageable. With such a configuration, by attaching the communication inhibiting member 43 excluding the distal end portion 45 of the first narrow pressure portion 43 to the soft bag 2, the distal end portion 45 is engaged with the proximal end portion 46. The periphery of the discharge port 7 can be held.
The first narrow pressure portion 43 and the second narrow pressure portion 44 are composed of housing portions 43a and 44a for housing the discharge port 7, and the first narrow pressure portion 43 and the second narrow pressure portion 44 are soft. Narrow pressure surfaces 43b and 44b for inhibiting communication between the inside of the bag 2 and the discharge port 7 and inhibition portions 43d and 44d for inhibiting insertion of the discharge port 7 from the outside of the discharge port 7d are provided. The first narrow pressure part 43 and the second narrow pressure part 44 are connected by the hinge part 19 and can be opened and closed. Since the accommodating portions 43a and 44a, the narrow pressure surfaces 43b and 44b, and the inhibiting portions 43d and 44d are the same as the accommodating portions 37a and 38a, the narrow pressure surfaces 37b and 38b, and the inhibiting portions 37d and 38d, the above description is referred to.

In the embodiment of the present invention, the breakable portion 42 is provided between the proximal end portions of the opening end portions of the first narrow pressure portion 43 and the second narrow pressure portion 44 as shown in FIG. . The breakable part of the embodiment of the present invention is a thin part provided between the first narrow pressure part and the second narrow pressure part. The thin portion is manufactured by forming a groove portion having a V-shaped cross section. Specifically, the angle of the groove is preferably 30 to 120 °, particularly 40 to 60 °, and the minimum thickness is preferably 0.05 to 0.3 mm, particularly 0.08 to 0.2 mm. By producing the groove forming portion at such an angle, when the soft bag 2 is inflated, the stress concentrates at the center of the breakable portion, and the groove is reliably broken. Further, the groove portion may have any shape as long as it is easily broken, and is not limited to the V shape as in the embodiment, and may be a semicircular shape, a semielliptical shape, or the like. Moreover, although the breakable part of the present invention can be broken by forming a thin part by forming a groove part, it is not limited to this. The breakable portion may be produced by, for example, forming a portion forming the breakable portion of the medicine storage portion with a material more fragile than the other portions. Specifically, it is preferable that a part forming the breakable part is made of an easily breakable material by multicolor molding, and the other part is made of a material that is not easily broken.
With such a configuration, it is possible to prevent the medicine from being administered from the discharge port 7 before the medicines in the first medicine chamber 3 and the second medicine chamber 4 are mixed.
The openable strength of the breakable portion 42 is preferably greater than the peel strength of the partition weak seal portion 12. Specifically, the openable strength is preferably 2 to 14N, particularly 5 to 10N.

  When the communication inhibiting member 41 is attached so as to accommodate the discharge port 7, the soft bag 2 around the discharge port 7 is formed by the narrow pressure surface 43 b and the narrow pressure surface 44 b of the first narrow pressure portion 43 and the second narrow pressure portion 44. Is pressed from one surface and the other surface to form the partition portion 25. A fourth drug chamber 26 independent of the first drug chamber 3 is formed in the partition portion 25. Moreover, the insertion from the outside to the discharge port 7d is inhibited by the inhibition portions 43d and 44d. As a result, communication between the first medicine chamber 3 and the discharge port 7 is hindered. For this reason, administration of a chemical | medical solution can be prevented before mixing the chemical | medical agent in the soft bag 2. FIG.

In addition, the narrow pressure state by the narrow pressure portions 43 and 44 is simultaneous with or separated from the separation of the partition weak seal portion 12 by the pressing of the first drug chamber 3 and the second drug chamber 4 as shown in FIG. Subsequently, the narrow pressure portions 43 and 44 are released by the spread of the soft bag 2 to be released. When the first medicine chamber 3 or the second medicine chamber 4 is pressed, the communication inhibiting member 41 is less likely to be opened than the partition weak seal portion 12. Specifically, it is preferable that the opening strength of the communication inhibiting member 41 is greater than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. . Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the communication inhibiting member 41 in this order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the openable strength of the communication inhibiting member 41 is 2. To 14N, in particular 5 to 10N.
Further, the communication inhibiting member 41 of this embodiment may also include the narrow pressure state release assisting portions 15c and 16c as in the communication inhibiting member 14 shown in FIGS. The narrow pressure state release assisting part is as described above.

The method for manufacturing and using the medical container 40 is preferably substantially the same as the medical container 35 described above.
Next, a medical container 50 according to another embodiment will be described with reference to the accompanying drawings.
23 is a front view of a medical container according to another embodiment of the present invention, FIG. 24 is a cross-sectional view taken along the line DD of the medical container shown in FIG. 23, and FIG. 25 is a medical container shown in FIG. FIG. 26 is a side view of the discharge inhibiting member shown in FIG. 25, FIG. 27 is a development view of the discharging inhibiting member shown in FIG. 25, and FIG. 28 is shown in FIG. 29 is a front view of the discharge port used for the medical container, FIG. 29 is a side view of the discharge port shown in FIG. 28, FIG. 30 is a cross-sectional view of the drug container shown in FIG. FF sectional drawing of the chemical | medical agent container shown in FIG. 32, FIG. 32 is explanatory drawing for demonstrating the usage method of the medical container shown in FIG.
As shown in FIG. 23, the medical container 50 includes a soft bag 2 whose internal space is divided into a first drug chamber 3 and a second drug chamber 4 by a partition weak seal portion 12, and a first drug chamber. 3, the first medicine 5 housed in the second medicine chamber 6, the second medicine 6 housed in the second medicine chamber 4, the mixed injection port 11 attached to the upper end 24 of the soft bag 2, and the lower end 22 The container main body 50a provided with the attached discharge port 51, and the discharge inhibiting member 64 attached to the soft bag 2 of the container main body 50a are provided.

The medical container 50 of this embodiment is different from the medical container 30 only in the configuration of the discharge port and the discharge inhibiting member. Other configurations are the same as the above-described medical container, so the above description is referred to.
Further, the discharge port 51 is made of a hard or semi-rigid material, and has a cylindrical portion 53 whose front end portion is closed and whose rear end portion is sealed so as to be piercable, and at least the front end portion of the cylindrical portion 53. A first stress applying portion 56 and a first stress applying portion 56 that are provided so as to sandwich the breakable portion 54 provided and the breakable portion 54 of the cylindrical portion 53 and are fixed to one sheet 2a of the first drug chamber 3. The second stress applying portion 57 that is fixed to the other sheet 2 b of the drug chamber 3 is provided, and the breakable portion 54 is broken by the spread between the first stress applying portion 56 and the second stress applying portion 57. Then, the cylindrical portion 53 is opened.
As shown in FIGS. 28 to 31, the discharge port 51 includes a first stress applying portion 56, a second stress applying portion 57, a tubular portion 53, and a breakable portion provided in the tubular portion 53. 54 and a lid portion 59 that seals the rear end portion of the tubular portion 53. Hereinafter, the discharge port 51 will be described with the “upper side” in FIGS. 28 to 31 as the “front end side” and the “lower side” in FIGS. 28 to 31 as the “base end side”. Moreover, the cylindrical part 53 has the soft bag attaching part 58 for attaching to the soft bag 2 in a base end part, as shown to FIG. 21, FIG.

As shown in FIGS. 30 and 31, the cylindrical portion 53 has a distal end portion closed and a proximal end portion opened. In this embodiment, the flange portion 53a and the first cylinder are sequentially formed from the proximal end side. A portion (soft bag attaching portion) 53b, a tapered portion 53c that is continuous with the first cylindrical portion 53b and decreases in a tapered shape toward the distal end side, a second cylindrical portion 53d that is continuous with the tapered portion 53c, 2 a cylindrical portion 53d and a continuous closed portion (tip portion) 53e. The shape of the tip 53e is a truncated cone shape in the embodiment of the present invention. The shape of the tip may be a dome shape, a cone shape, or the like.
Moreover, the cover part attaching part 53f which attaches the cover part 59 is formed in the base end side of the flange part 53a.
As shown in FIGS. 30 and 31, the lid portion 59 seals the opening at the proximal end portion of the tubular portion 53 so that it can be pierced. The lid portion 59 includes a tubular member 59a and a seal member 59b that closes the base end opening of the tubular member 59a so as to be pierced.

  The seal member preferably has a self-occlusion property, and after the needle tube is pulled out from the elastic body, the puncture hole is closed to prevent leakage of the chemical solution. Examples of the constituent material of the sealing material include polyolefins such as polyethylene, polypropylene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, and cross-linked ethylene-vinyl acetate copolymer, polyester, polyvinyl chloride, polyurethane, Flexible polymer materials such as polyamide, thermoplastic resins such as polyamide elastomer and polyester elastomer (thermoplastic elastomer), natural rubber, isoprene rubber, silicone rubber, butadiene rubber, various rubber materials such as styrene-butadiene rubber, etc. An elastic material or a combination of any two or more of these materials can be used, and those containing an elastic material are preferable from the viewpoint of sealing performance and resealability. Moreover, as a port, it is preferable that it is a cylindrical and elliptical cylinder-shaped molded article.

  Further, when the cylindrical portion 53 is directly attached to the soft bag 2, the portion of the cylindrical portion 53 that is joined to the soft bag 2 (the soft bag attaching portion 58 in the embodiment of the present invention) is compatible with the soft bag 2. It is preferable to be formed of a certain resin. Thereby, the cylindrical part 53 becomes what adheres to the soft bag 2 easily. In the embodiment of the present invention, a resin layer compatible with the forming material of the soft bag 2 (particularly, the forming material forming the inner surface side of the soft bag 2) is provided on the outer surface of the cylindrical portion 53 (see FIG. Not shown). Specifically, the resin layer is formed on the circumference of the outer surface of the cylindrical portion 53. Examples of compatible resins include polyolefins (eg, polyethylene, polypropylene, polybutadiene, ethylene-propylene copolymers, mixtures containing polyolefin such as a mixture of polypropylene and polyethylene or polybutene), and partially crosslinked products thereof, ethylene-vinyl acetate. A copolymer (EVA), polyester (polyethylene terephthalate, polybutylene terephthalate, etc.), soft vinyl chloride resin, polyvinyl acetate, polyvinylidene chloride, silicone, polyurethane, polyamide elastomer, polyester elastomer and the like are preferable. In addition, the compatible resin is preferably a material that is the same as or similar to the sheet material constituting the soft bag 2. The compatible resin may be coated on the cylindrical portion 53 by molding in two colors. In this case, it is not necessary to provide a compatible resin layer on the outer surface of the cylindrical portion 53.

The breakable portion 54 is configured such that when stress is applied by the first stress applying portion 56 and the second stress applying portion 57, the portion constituting the cylindrical portion 53 can be vertically divided. Preferably it is. The breakable portion 54 is preferably provided from the distal end portion of the cylindrical portion 53 to the vicinity of the proximal end portion. Since the breakable portion 54 is provided up to the vicinity of the proximal end portion of the tubular portion 53, the medicine in the tubular portion 53 can be reliably discharged when the breakable portion 54 is broken. As shown in FIGS. 28 and 29, the breakable portion 54 is provided from the tip of the tubular portion 53 to the vicinity of the tip of the first cylindrical portion 53b. The breakable portion 54 may be formed only at the tip side portion of the cylindrical portion 53.
As shown in FIG. 29, the breakable portion 54 is provided so as to pass between the first stress applying portion 56 and the second stress applying portion 57 in the vicinity of the distal end portion of the cylindrical portion 53, and on the proximal end side. An extended distal end side portion 54a, and a first stress applying portion side portion 54b and a second stress applying portion side portion 54c that branch from the vicinity of the proximal end portion of the distal end side portion 54a and extend in the lateral direction of the tubular portion 53. have. And the 1st stress application part side part 54b and the 2nd stress application part side part 54c are provided so that the base end parts of the front end side part 54a may be connected. With this configuration, when the first stress applying portion 56 and the second stress applying portion 57 are spread, the breakable portion 54 is broken and the tubular portion 53 is opened.

  The first stress applying portion 56 extends from one sheet 2 a side portion in the vicinity of the front end portion of the tubular portion 53, and the second stress applying portion 57 is the other sheet in the vicinity of the front end portion of the tubular portion 53. It extends from the 2b side portion. When the second drug chamber 4 is pressed, the breakable portion 54 is located near the fixing portion 60 of the first stress applying portion 56 with respect to the soft bag 2 and the fixing portion 61 of the second stress applying portion 57 with respect to the soft bag 2. By swelling, it breaks to the one sheet 2a side and the other sheet 2b side. Further, as shown in FIG. 29, the distal end side portion 54a preferably passes between the first stress applying portion 56 and the second stress applying portion 57 and extends toward the proximal end side. The front end side portion 54a passes through the vicinity of the middle between the first stress applying portion 56 and the second stress applying portion 57 of the cylindrical portion 53, and passes through the vicinity of the middle between one sheet side and the other sheet side. It extends to the vicinity of the proximal end portion of the medicine container. The distal end side portion 54 a is formed in the vertical direction along the outer surface of the tubular portion 53 from the distal end portion to the proximal end side of the tubular portion 53. The distal end side portion 54a is formed continuously from the distal end portion to the proximal end side. With such a configuration, as shown in FIG. 32, when the second drug chamber 4 is pressed to inflate the first drug chamber 3, the cylindrical portion 53 is placed on one sheet 2a side and the other sheet 2b side. Can be torn.

As shown in FIG. 29, the first stress applying portion side portion 54b and the second stress applying portion side portion 54c of the breakable portion 54 are provided so as to be orthogonal to the distal end side portion 54a of the breakable portion 54. Yes. Moreover, the opening holding member side portions 54b and 54c of the breakable portion are formed in a substantially arc shape. Since the breakable portion 54 is configured as in the embodiment shown in FIG. 29, the tip side portion of the cylindrical portion 53 is more cylindrical than the first cylindrical portion 53 b as shown in FIG. It is separated from the base end side portion. The breakable portion 54 is a fragile portion that can be broken as described above. Specifically, the breakable part is a thin part. The breakable portion 54 is preferably produced by forming a groove on the outer surface of the tubular portion 53. Further, the first stress applying portion side portion 54b and the second stress applying portion side portion 54c may be formed in a substantially arc shape, a substantially elliptic arc shape, or a U-shape.
Specifically, the breakable part of the embodiment of the present invention is produced by forming a groove part having a V-shaped cross section. Specifically, the angle of the groove is preferably 30 to 120 °, particularly 40 to 60 °, and the minimum thickness is preferably 0.05 to 0.3 mm, particularly 0.08 to 0.2 mm. By producing the groove forming portion at such an angle, when the soft bag 2 is inflated, the stress concentrates at the center of the breakable portion, and the groove is reliably broken. Further, the groove portion may have any shape as long as it is easily broken, and is not limited to the V shape as in the embodiment, and may be a semicircular shape, a semielliptical shape, or the like. Moreover, although the breakable part of the present invention can be broken by forming a thin part by forming a groove part, it is not limited to this. The breakable portion may be produced by, for example, forming a portion forming the breakable portion of the medicine storage portion with a material more fragile than the other portions. Specifically, it is preferable that a part forming the breakable part is made of an easily breakable material by multicolor molding, and the other part is made of a material that is not easily broken.

The breakable portion 54 may be anything as long as it can break the tubular portion 53 by the stress applied by the first stress applying portion 56 and the second stress applying portion 57.
In this embodiment, the first stress applying portion 56 and the second stress applying portion 57 extend from the vicinity of the distal end portion of the tubular portion 53 as shown in FIGS. Is a free end. With such a configuration, when the first stress applying unit 56 and the second stress applying unit 57 are given a force to open them, the force is converted into a stress for breaking the breakable portion 54. It has a function to do. The first stress applying part 56 and the second stress applying part 57 are preferably formed so as to face each other. The main body portions of the first stress applying portion 56 and the second stress applying portion 57 are preferably formed in a vertically long rectangular shape. With such a configuration, when the soft bag 2 is pressed and inflated, the first stress applying portion 56 and the second stress applying portion 57 reliably apply the breaking stress to the breakable portion 54.

Specifically, as shown in FIGS. 28 to 31, the first stress applying portion 56 and the second stress applying portion 57 are provided on each of the vertically long flat plate portions 56 a and 57 a and on both sides of the flat plate portions 56 a and 57 a. The formed side wall portions 56b and 57b, the joined portions 56d and 57d joined to the sheet constituting the soft bag 2, the ribs 56e and 57e formed on the side wall portions, and the inner surfaces of the flat plate portions 56a and 57a. Ribs 56c and 57c and reinforcing ribs 56f and 57f are provided.
The first stress applying part 56 and the second stress applying part 57 are preferably provided so as to face each other and slightly apart. Since it has such a structure, even if it presses between the 1st stress provision part 56 and the 2nd stress provision part 57 at the time of fixation to the soft bag 2, the 1st stress provision part 56 and the 1st The amount of deformation allowed for the second stress applying portion 57 is small, and the breakable portion 54 is not likely to break. In the embodiment of the present invention, the flat plate portions 56a and 57a are preferably arranged so as to face each other. The side wall portions 56b and 57b of the embodiment of the present invention are formed such that the tip end portion is high and the base end portion is low. As shown in FIGS. 29, 30 and 31, ribs 56e and 57e are formed on the tip side portions of the side wall portions 56b and 57b. The rib 56e and the rib 57e are provided at positions facing each other. With such a configuration, the first stress applying unit 56 and the second stress applying unit 57 are slightly separated from each other. The ribs are preferably separated from each other by 0.1 to 3.0 mm, particularly 0.3 to 1.5 mm.

  The ribs 56 c and 57 c are provided on the respective surfaces of the first stress applying part 56 and the second stress applying part 57 facing each other. In the embodiment of the present invention, the ribs 56c and 57c are provided from the tip of the cylindrical portion 53 of the flat plate portions 56a and 57a to the tip of the flat plate portions 56a and 57a near the center of the inner surface of the flat plate portions 56a and 57a. Yes. Further, the ribs may be arranged at positions where they do not contact each other (not shown). Specifically, the first stress applying unit 56 and the second stress applying unit 57 are staggered from the center in the axial direction of the first stress applying unit 56 or the second stress applying unit 57 to the side surface side. It may be provided at a position. For this reason, the ribs 56c and 57c do not contact each other. With such a configuration, the tensile stress or tear stress applied to the first stress applying portion 56 and the second stress applying portion 57 is reliably transmitted to the breakable portion 54, so that the breakable portion 54 is broken. It becomes easy. The heights of the ribs 56c and 57c are increased from the distal end toward the proximal end side.

As shown in FIGS. 28 and 29, the reinforcing ribs 56f and 57f are provided on the outer surface of the flat plate portions 56a and 57a from the tip of the cylindrical portion 53 to the vicinity of the middle portion of the flat plate portions 56a and 57a. The reinforcing ribs 56f and 57f are reduced in diameter from the distal end portion of the cylindrical portion 53 toward the distal end side. By having the reinforcing ribs 56f and 57f, the first stress applying portion 56 and the second stress applying portion 57 can reliably apply stress to the vicinity of the distal end portion of the cylindrical portion 53.
The joint portions 56d and 57d are flat portions on the inner surface of the flexible bag 2 on the outer surfaces of the flat plate portions 56a and 57a. The joint portions 56d and 57d are formed in a rectangular shape and are flat. The joint portions 56 d and 57 d are formed at the tip side portions of the first stress applying portion 56 and the second stress applying portion 57.

  In the embodiment of the present invention, it is preferable that at least a part of the outer surfaces of the first stress applying portion 56 and the second stress applying portion 57 are formed of a material that can be fixed to the inner surface of the soft bag 2. Specifically, at least a part of the joining portions 56d and 57d is formed of a material that can be fixed to the inner surface of the soft bag 2. Specifically, the joint portions 56d and 57d to be joined to the inner surface of the soft bag 2 are partly or wholly formed of a material for forming the soft bag 2 (particularly, a material for forming the inner surface side of the soft bag 2). It is preferably formed of a compatible resin. With such a configuration, the first stress applying portion 56 and the second stress applying portion 57 can be reliably bonded to the inner surface of the flexible bag 2. The resin compatible with the soft bag 2 is preferably the resin described above. The compatible resin is preferably a material that is the same as or similar to the constituent material of the soft bag. In the embodiment of the present invention, the compatible resin layer is preferably produced by two-color molding. In addition, you may produce all the 1st stress provision parts or the 2nd stress provision part with resin compatible with the soft bag of a chemical | medical agent container. The compatible resin layer is preferably made flat so as to be easily joined to the inner surface of the soft bag.

Then, in the medical container 50, as shown in FIGS. 23 and 24, the whole or a part of the joining portion 56d of the first stress applying portion 56 is joined to the inner surface of the sheet 2a of the flexible bag 2. Similarly, the first fixing portion 60 is formed. Similarly, the whole or a part of the joining portion 57d of the second stress applying portion 57 is joined to the inner surface of the sheet 2b of the flexible bag 2 to thereby provide the second fixing. A portion 61 is formed. For this reason, the first stress applying part 56 and the second stress applying part 57 are fixed to the first stress applying part 56 and the second stress applying part 57 of the soft bag 2 when the drug chamber is pressed, It spreads following the spread between 61, and a breakable portion, which will be described later, is opened to the one sheet 2a side and the other sheet 2b side to break.
The joining of the joining portion 56d of the first stress applying portion 56 and the joining portion 57d of the second stress applying portion 57 and the inner surface of one sheet 2a, 2b of the soft bag 2 is performed by ultrasonic fusion, high frequency fusion, It is preferably performed by heat fusion or the like. Specifically, after the discharge port 51 is arranged at a position as shown in FIG. 16, it is sandwiched from both sides of the surface of the one sheet 2a and the other sheet 2b of the flexible bag 2 by a sealing mold and heat sealed. Preferably, it is done.
Moreover, it is preferable that the 1st stress provision part 56 or the 2nd stress provision part 57 is the structure which can carry | support and spread from the exterior of the soft bag 2. FIG.
The first stress applying portion and the second stress applying portion of the present invention are not limited to those having the above-described configuration, and can be joined to one sheet inner surface and the other sheet inner surface constituting the soft bag 2. In addition, any configuration may be used as long as it is configured to apply stress to the breakable portion in conjunction with the swelling of the soft bag. For example, it may not be formed to extend in the axial direction of the medicine container, but may be formed obliquely with respect to the medicine container.

  As the constituent material of the discharge port of the present invention, a hard resin or a semi-hard resin is used. Specifically, rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, cyclic polyolefin [specifically, ZEONEX (manufactured by ZEON Corporation), APEL (manufactured by Mitsui Chemicals, Inc.)], polypropylene homopolymer, high density polyethylene Such as polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, ABS resin, acrylic resin, polymethyl methacrylate (PMMA), polyacetal, polyarylate, polyacrylonitrile, polyvinylidene fluoride, ionomer, acrylonitrile-butadiene -Styrene copolymers, polyesters such as polyethylene terephthalate (PET), polybutylene terephthalate (PBT), butadiene-styrene copolymers, aromatic or aliphatic polymers. Amides of various resins, or those in which any combination of these and the like. Among these, hard polyvinyl chloride, polyethylene, polypropylene, and polyester are preferable because they are highly safe and have excellent adhesion to the soft bag 2. Further, the above-described hard or semi-hard resin is preferable as the constituent material of the lid member.

The breakable portion 54 is preferably one that is less likely to peel off than the partition weak seal portion 12 when the second drug chamber 4 is pressed. Specifically, the breaking strength of the breakable portion 54 is preferably greater than the sealing strength of the partition weak seal portion 12. The breaking strength of the breakable portion 54 (initial breaking strength of the tip side portion 54a) is preferably 0.5 to 14N, and particularly preferably 2 to 10N.
The difference between the discharge inhibiting member 64 and the above-described discharge inhibiting member 31 is that the lengths of the first sandwiching portion and the second sandwiching portion and the holding state holding portions 17 are provided on both sides of the lower end portion of the sandwiching portion. However, the substantial configuration is the same.

As shown in FIGS. 25 to 27, the discharge inhibiting member 64 includes a first sandwiching portion 65, a second sandwiching portion 66, a holding portion 17, and a hinge portion 19. The first sandwiching portion 65 and the second sandwiching portion 66 are connected by a hinge portion 19 and can be opened and closed.
The first sandwiching portion 65 and the second sandwiching portion 66 include housing portions 65a and 66a for housing the discharge port 51, and an inhibition portion 65b for inhibiting external insertion of the discharge port 51 into the discharge port 51d . 66b .
The first sandwiching portion 65 and the second sandwiching portion 66 differ only in the structure of the first sandwiching portion 37, the second sandwiching portion 38, and the distal end side portion of the communication inhibiting member 36. As shown in FIGS. 25 and 26, the first sandwiching portion 65 and the second sandwiching portion 66 accommodate the entire discharge port 51.
The main body portions of the first sandwiching portion 65 and the second sandwiching portion 66 are semi-cylindrical portions having a reduced diameter at the distal end portion and a bottom portion at the proximal end portion. Flat plate portions 65d and 66d are formed at the tip of the main body.

Specifically, as shown in FIG. 26, the opening end portions of the front end portions of the main body portions of the first sandwiching portion 65 and the second sandwiching portion 66 are inclined outward. With such a configuration, the distal end side portions excluding the distal end portions of the first sandwiching portion 65 and the second sandwiching portion 66 are largely separated from each other toward the distal end side. The flat plate portions 65d and 66d are portions that reliably receive stress due to the spread of the soft bag 2. The tip side portions of the first sandwiching portion 65 and the second sandwiching portion 66 are non-narrow pressure portions that do not narrow the soft bag 2 in the sandwiched state.
In the embodiment of the present invention, like the first sandwiching portion 15 and the second sandwiching portion 16, the first sandwiching portion 65 and the second sandwiching portion 66 are reduced in diameter at the distal end portion to the proximal end portion. It is a semi-cylindrical part having a bottom part. Inside the semi-cylindrical part, as shown in FIG. 27, accommodating parts 65a and 66a for accommodating the discharge port 51 are provided. The first sandwiching portion 65 and the second sandwiching portion 66 have the same configuration. By overlapping the first sandwiching portion 65 and the second sandwiching portion 66, the entire discharge port 7 can be accommodated inside.

In the embodiment of the present invention, the base end portions of the first sandwiching portion 65 and the second sandwiching portion 66 are the inhibition portions 65b and 66b. Specifically, since a wall surface (bottom portion) is formed at the proximal end portions of the first sandwiching portion 65 and the second sandwiching portion 66, the needle tube cannot be inserted into the discharge port 51d from behind. The first sandwiching portion and the second sandwiching portion only need to cover at least the vicinity of the discharge port 51d of the discharge port 7.
Further, the discharge inhibiting member 64 can be attached to the hole 23 provided in the upper end portion (upper end side seal portion) 24 or the lower end portion (lower end side seal portion) 22 of the soft bag 2. The discharge inhibiting member 64 according to the embodiment of the present invention can be attached to the hole 23 provided in the lower end portion by fitting the holding portion 17 through the hole 23.

The holding state holding unit 17 is a connecting unit that connects the first holding unit 65 and the second holding unit 66 in a state in which the holding state is held. It is preferable that the connection between the first sandwiching portion 65 and the second sandwiching portion 66 is released when the sandwiching portion 65 and the second sandwiching portion 66 are expanded. The connecting portions 17 are provided on both sides of the outer surfaces of the base end portions of the first sandwiching portion 65 and the second sandwiching portion 66. Since the configuration of the connecting portion 17 itself is as described above, the above description is referred to.
Further, as shown in FIG. 32, the pinching state by the pinching portions 65 and 66 is simultaneous with or following the peeling of the partition weak seal portion 12 due to the pressing of the first drug chamber 3 and the second drug chamber 4. It is released when the sandwiching portions 65 and 66 are expanded by the spread of the soft bag 2. When the first drug chamber 3 or the second drug chamber 4 is pressed, the discharge inhibiting member 64 is less likely to be opened than the partition weak seal portion 12. Specifically, the opening strength of the discharge inhibiting member 64 is preferably greater than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. .

  Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the discharge inhibiting member 64 in this order with one action. Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the discharge inhibiting member 64 in this order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the discharge inhibiting member 64 has an openable strength of 2. To 14N, in particular 5 to 10N.

Next, the usage method of the medical container 50 of this invention is demonstrated.
First, when the second drug chamber 4 of the medical container 1 is strongly pressed with a finger or the like, the partition weak seal portion 12 is first broken, and then the first drug chamber 4 flows into the first drug chamber 4 due to the inflow of the drug solution. The drug room 3 expands. First, the discharge inhibiting member 64 is opened as shown in FIG. 32, then the tip side portion 54a of the breakable portion 54 of the discharge port 51 is broken, and then the first stress applying portion side portion 54b and The second stress applying part side portion 54c is broken. Then, the discharge inhibiting member 64 is removed from the soft bag 2 and the insertion needle is inserted into the discharge port 51d of the discharge port 51 to perform drug administration.

Next, the medical container 70 of the present invention will be described. 33 is a front view of a medical container according to another embodiment of the present invention, FIG. 34 is a cross-sectional view taken along the line GG of the medical container shown in FIG. 33, and FIG. 35 is a medical container shown in FIG. front view of the communicating inhibitory member used, FIG. 36 is a side view of the communication inhibiting member shown in FIG. 35, FIG. 37 is a developed view of the communication inhibiting member shown in FIG. 35, FIG. 38, FIG. 33 It is explanatory drawing for demonstrating the usage method of a medical container.
The medical container 70 of the present invention differs from the medical container 35 only in the configuration of the discharge port and the communication blocking member. Since other configurations are the same as those of the medical container 35, description thereof is omitted.
Moreover, since the discharge port used for the medical container is the same as the discharge port 51 used for the medical container 50, the above description is referred to.
As shown in FIGS. 35 to 37, the communication inhibiting member 71 inhibits both the communication between the discharge port 51 and the soft bag 2 and the external insertion of the discharge port 51 into the discharge port 51d. .

As shown in FIGS. 35 to 37, the communication inhibiting part 72 includes narrow pressure parts 72 and 73, a holding part 17, and a hinge part 19.
With such a configuration, the communication inhibiting member 71 can prevent drug administration before the drug is mixed, and can easily prepare for drug administration.
The narrow pressure portion includes a first narrow pressure portion 72 and a second narrow pressure portion 73 for sandwiching the periphery of the discharge port 51 from one surface and the other surface of the soft bag 2. The first narrow pressure part 72 and the second narrow pressure part 73 are connected by the hinge part 19 and can be opened and closed. In addition, you may not provide a hinge part.
As shown in FIGS. 35 to 37, the first narrow pressure portion 72 and the second narrow pressure portion 73 include accommodating portions 72a and 73a for accommodating the discharge port 51 and inhibiting portions 72d and 73d. . The open ends of the first narrow pressure portion 72 and the second narrow pressure portion 73 are narrow pressure surfaces 72 b and 73 b that inhibit communication between the inside of the soft bag 2 and the discharge port 51.

The accommodating portions 72 a and 73 a of the first narrow pressure portion 72 and the second narrow pressure portion 73 of the embodiment accommodate the entire discharge port 51. The accommodating parts 72a and 73a cover the periphery of the discharge port 51d so as to inhibit insertion from the outside. For this reason, the communication blocking member 71 shown in the embodiment inhibits the communication between the discharge port 51 and the inside of the soft bag 2 and prevents the insertion of the discharge port 51 from the outside to the discharge port 51d.
In the embodiment of the present invention, the first narrow pressure portion 72 and the second narrow pressure portion 73 are semi-cylindrical portions having a reduced diameter at the distal end and a bottom at the proximal end. Inside the semi-cylindrical part, as shown in FIGS. 36 and 37, accommodating parts 72a and 73a for accommodating the discharge port 51 are provided. The first narrow pressure portion 72 and the second narrow pressure portion 73 have the same configuration. By overlapping the first narrow pressure portion 72 and the second narrow pressure portion 73, the entire discharge port 51 can be accommodated inside.

In the embodiment of the present invention, the base end portions of the first narrow pressure portion 72 and the second narrow pressure portion 73 are the inhibition portions 72d and 73d. Specifically, since a wall surface (bottom portion) is formed at the proximal end portions of the first narrow pressure portion 73 and the second narrow pressure portion 73, the needle tube cannot be inserted into the discharge port 51d from behind. . In addition, the 1st clamping part and the 2nd clamping part should just cover the discharge port 51d vicinity of the discharge port 51 at least.
And the opening part of a semi-cylindrical part is the narrow pressure surfaces 72b and 73b. In the embodiment of the present invention, in a state where the first narrow pressure portion 72 and the second narrow pressure portion 73 sandwich the soft bag 2, the narrow pressure surface 72 b and the narrow pressure surface 73 b are continuous sheets around the discharge port 51. Then, the partition portion 25 is formed.
The narrow pressure surfaces 72b and 73b are preferably formed so that the portion pressing around the discharge port 51 has a substantially semi-elliptical shape or a substantially circular shape. As the shape of the narrow pressure surface, the shape of the portion that presses around the discharge port 51 may be U-shaped, trapezoidal, triangular with the apex down, V-shaped, or the like. The narrow pressure surfaces 72b and 73b are flat in the embodiment.

In the embodiment of the present invention, the base end portions of the first narrow pressure portion 72 and the second narrow pressure portion 73 are the inhibition portions 72b and 73b. Specifically, since a wall surface (bottom portion) is formed at the proximal end portions of the first narrow pressure portion 73 and the second narrow pressure portion 73, the needle tube cannot be inserted into the discharge port 51d from behind. . Note that the first Sema圧 portion second Sema圧 portion as long as it covers the vicinity of the discharge port 51d of at least the discharge port 51.
Further, the communication inhibiting member 71 can be attached to the hole 23 provided in the upper end portion (upper end side seal portion) 24 or the lower end portion (lower end side seal portion) 22 of the soft bag 2 as in the embodiment shown in FIG. It is preferable that The embodiment of the present invention can be attached to the lower end side seal portion 22 of the soft bag 2 by passing the pin 20 of the holding portion 17 through the hole 23 and fitting the holding portion 17.

The pinching state holding unit 17 is a connecting unit that connects the first narrow pressure unit 72 and the second narrow pressure unit 73 in a state where the pinching state of the narrow pressure units 72 and 73 is held. The first narrow pressure portion 72 and the second narrow pressure portion 73 are pushed and spread by the spread of the flexible bag 2 to release the connection between the first narrow pressure portion 72 and the second narrow pressure portion 73. Preferably there is.
The connecting portion 17 is preferably a fitting portion provided in the first narrow pressure portion 72 and the second narrow pressure portion 73. The connecting portion 17 can be inserted into an insertion path (an insertion hole in the embodiment) 18 provided in the first narrow pressure portion 72 and the insertion path 18, and the first narrow pressure portion 72 and the second narrow pressure portion are inserted. An insertion means (pin in the embodiment) 20 for holding the narrow pressure state of the portion 73 is provided. The outer diameter of the pin 20 is almost the same as the inner diameter of the hole 18. With this configuration, as shown in FIGS. 35 and 36, the first narrow pressure portion 72 and the second narrow pressure portion 73 are closed, and the pin 20 is inserted into the insertion hole 18 to be fitted. The narrow pressure state of the first narrow pressure portion 72 and the second narrow pressure portion 73 is maintained. As shown in FIG. 38, the pin 20 is removed from the insertion hole 18 due to the expansion of the first drug chamber 3, and the narrow pressure state is released. The connecting portion may be an engaging portion provided in the first narrow pressure portion and the second narrow pressure portion.

In addition, the narrow pressure state by the narrow pressure portions 72 and 73 is simultaneous with or separated from the separation of the partition weak seal portion 12 by the pressing of the first drug chamber 3 and the second drug chamber 4 as shown in FIG. Subsequently, the narrow pressure portions 72 and 73 are pushed and expanded by the expansion of the soft bag 2. When the first drug chamber 3 or the second drug chamber 4 is pressed, the communication inhibiting member 71 is less likely to be opened than the partition weak seal portion 12. Specifically, the opening strength of the communication inhibiting member 71 is preferably greater than the peel strength (initial peel strength) of the partition weak seal portion 12. With such a configuration, it is possible to prevent the medicine from being administered before mixing the first medicine 5 in the first medicine chamber 3 and the second medicine 6 in the second medicine chamber 4. . Further, when the second drug chamber 4 is pressed, it is preferable to open the partition weak seal portion 12 and the communication inhibiting member 71 in this order with one action. Specifically, the peel strength (initial peel strength) of the partition weak seal portion 12 is 0.5 to 10 N / 10 mm, particularly 2 to 6 N / 10 mm, and the openable strength of the communication inhibiting member 14 is 2. To 14N, in particular 5 to 10N.
Further, the communication inhibiting member 71 of this embodiment may also include the narrow pressure state release assisting portions 15c and 16c as in the communication inhibiting member 14 shown in FIGS. The narrow pressure state release assisting part is as described above.

  When the communication blocking member 71 is attached to the soft bag 2 so as to accommodate the discharge port 51 therein, the first narrow pressure portion 72 and the second narrow pressure portion 73 are pressed as shown in FIGS. By narrowing the soft bag 2 from one surface and the other surface so that the portions 72 b and 73 b surround the discharge port 51, the partition portion 25 is formed around the discharge port 51 in a semi-elliptical shape. In the partition 25, a fourth drug chamber 26 independent of the first drug chamber 3 is formed. The fourth drug chamber 26 is preferably not filled with a chemical solution, but may be filled with a small amount. With the configuration as described above, the first drug chamber 3 and the discharge port are configured so that the first drug 5 in the first drug chamber 3 hardly flows into the discharge port 51 side by the partition portion 25. Communication with 51 can be inhibited. For this reason, it can prevent administering a chemical | medical solution before mixing the chemical | medical agent in the soft bag 2. FIG.

Next, the usage method of the medical container 70 of this invention is demonstrated.
First, when the second drug chamber 4 of the medical container 1 is strongly pressed with fingers or the like, first, the partition weak seal portion 12 is broken, and then, as shown in FIG. The first medicine chamber 3 is expanded by the inflow of the chemical solution, the communication inhibiting member 71 is opened, and the inside of the soft bag 2 communicates with the discharge port. Then, the communication blocking member 71 is removed from the soft bag 2 and a drug is administered by inserting a penetration needle into the discharge port of the discharge port.

Next, a medical container which is another embodiment of the present invention will be described. 41 is a front view of a medical container according to another embodiment of the present invention, FIG. 42 is a cross-sectional view taken along line HH of the medical container shown in FIG. 41, and FIG. 43 is a medical container shown in FIG. It is a front view of the container main body used.
The medical container 80 differs from the medical container 30 shown in FIGS. 7 to 12 only in the configuration of the container main body, and the discharge inhibiting member 31 is the same. Therefore, the same reference is made to the above description.

  As shown in FIG. 41, the medical container 80 of this embodiment is a soft bag divided into a first drug chamber 3 and a second drug chamber 4 by a partition weak seal portion 12 whose internal space can be peeled off. 2, the first medicine 5 accommodated in the first medicine chamber 3, the second medicine 6 accommodated in the second medicine chamber 4, and the first medicine chamber 3 are attached. A container body 82 having a discharge port 7, a weak seal portion 81 for preventing communication between the first drug chamber 3 and the discharge port 7, and the discharge port 7 attached to the soft bag 2 of the container body 82. And a discharge inhibiting member 31 for inhibiting the external insertion into the discharge port 7d.

The discharge inhibiting member 31 holds the soft bag 2 sandwiched between the sandwiched portions 32 and 33 sandwiching the periphery of the discharge port 7 from one surface side and the other surface side of the soft bag 2, and the sandwiched portions 32 and 33. Pinching state holding portion 17 and hindering portions 32b and 33b covering the discharge port 7d so as to hinder the external insertion of the discharge port 7 into the discharge port 7d. Simultaneously with the separation of the weak seal portion 12 for partitioning by the pressing of the first drug chamber 3 or the second drug chamber 4, or simultaneously with the separation of the weak seal portion 81 for inhibiting communication due to the spread of the soft bag 2, When the sandwiching portions 32 and 33 are pushed and expanded slightly before and after, the discharge inhibiting member 31 can be detached from the soft bag 2.
The discharge inhibiting member 31 of the present invention is attached by sandwiching the soft bag 2 with the sandwiching portions 32 and 33, and can be removed from the soft bag 2 by releasing the sandwiching state of the sandwiching portions 32 and 33. Yes.
The discharge inhibiting member 31 does not hinder the communication between the inside of the soft bag 2 and the discharge port 7 unlike the discharge inhibiting member 14, and is inserted from the outside into the discharge port 7d of the discharge port 7 (specifically, Only the needle tube of the infusion set) is inhibited. The discharge inhibiting member 31 differs from the discharge inhibiting member 14 only in the configuration of the first sandwiching portion 32 and the second sandwiching portion 33.

For the specific configuration of the discharge inhibiting member 31, the above description should be referred to.
The container body 82 used in this embodiment is made of a flexible material, and the inner space is separated from the first drug chamber 3 and the second drug chamber 4 by the partition weak seal portion 12 that can be peeled off. The separated container body 82, the discharge port 7 communicating with the lower end of the first drug chamber 3, the first drug stored in the first drug chamber 3, and the second drug chamber 4 are stored. In addition, a weak seal portion 81 for inhibiting communication is provided that inhibits communication between the second medicine and the first medicine chamber 3 and the discharge port 7.
Furthermore, in the medical container 80 of this embodiment, the partition weak seal portion 12 includes a first weak seal portion 12a and a second weak seal portion 12b that is more difficult to peel off than the first weak seal portion 12a. . In particular, in the container main body 82 of this embodiment, the partitioning weak seal portion 12 is provided on both sides of the first weak seal portion 12a and the first weak seal portion 12a and peels off from the first weak seal portion 12a. The second weak seal portion 12b which is difficult is provided. In all the embodiments described above, the partitioning weak seal portion 12 may include a second weak seal portion 12b that is more difficult to peel off than the first weak seal portion 12a.

The difference between the container main body 82 used in this embodiment and the above-described container main body 10 is only the difference in the configuration of the weak seal portion 81 for blocking communication and the weak seal portion 12 for partitioning. Reference should be made to the description.
In the container main body 82 of this embodiment, as shown in FIG. 43, the partitioning weak seal portion 12 includes the first weak seal portion 12a and the first weak seal portion 12a provided on both sides of the first weak seal portion 12a. 2nd weak seal part 12b which is hard to peel from a part.
With such a configuration, by pressing the second drug chamber 4, the first weak seal portion 12a is not peeled off or prior to peeling of the second weak seal portion 12b. Peels off. Then, a fluid such as a liquid (specifically, a chemical solution and a gas) flows into the first drug chamber 3 from the peeling portion (the peeled first weak seal portion). The first medicine chamber 3 is pushed and expanded by the inflow of the fluid such as the liquid, and the internal pressure of the first medicine chamber is also increased by continuing the pressing of the second medicine chamber 4. When a fluid such as a liquid flows in, the first weak seal portion 12a becomes a peeling portion, and the whole partition weak seal portion 12 does not peel. For this reason, the first drug chamber 3 receives an inflow of a fluid such as a liquid in a state where the capacity does not increase so much. Therefore, the first drug chamber 3 is reliably expanded, and the weak seal portion 81 for communication inhibition is reliably peeled accordingly. Further, by pressing the first medicine chamber 3, the weak seal portion 81 for communication inhibition is peeled off together with the first weak seal portion 12a or with a slight delay.
Therefore, regardless of which drug chamber is pressed, a single operation is performed in which one drug chamber is pressed for the communication operation between the first drug chamber and the second drug chamber and the peeling operation of the weak seal portion for blocking communication. Can be performed.

In the container main body 82 of this embodiment, the partition weak seal portion 12 is formed so as to cross the container main body 82 in the entire lateral direction, as shown in FIG. Moreover, the partition weak seal part 12 is formed by fusing the sheet material of the container main body 82 in a band shape.
As shown in FIG. 43, the first weak seal portion 12a is provided in the vicinity of the center of the container main body 82, and the second weak seal portion 12b is formed from both sides to the side of the container main body 82 or near the side. ing. In this embodiment, the first weak seal portion 12a is preferably provided above the communication inhibiting weak seal portion 81, specifically, vertically above. Moreover, it is preferable that the 2nd weak seal part 12b is provided in the both sides of the position above the weak seal part 81 for a communication inhibition so that it may show in figure. Since the weak seal portion for preventing communication is provided at such a position, when the first weak seal portion is peeled off, the portion where the weak seal portion for preventing communication is formed swells greatly. The seal portion is easily peeled off. In the embodiment of the present invention, the first weak seal portion 12a and the second weak seal portion 12b are formed to have substantially the same width except for both side portions. In this embodiment, both side portions of the second weak seal portion 12b are formed wide. As shown in FIG. 43, strong seal portions 13 that cannot be substantially peeled off are provided at both ends of the partition weak seal portion 12 (second weak seal portion 12b in the embodiment of the present invention). Preferably it is. In addition, the 1st weak seal part or the 2nd weak seal part does not need to be formed in strip | belt shape. Further, in this embodiment, the discharge port and the communication blocking weak seal portion are provided in the vicinity of the center in the lateral direction of the container body 82, and accordingly, the first weak seal portion 12 a also corresponds to the container body 82. It is provided near the center in the horizontal direction. In the case where the discharge port and the weak seal portion for inhibiting communication are provided at a position close to one side of the container main body 82, the first weak seal portion is also correspondingly near the center in the lateral direction of the container main body. It is preferable to provide at a position close to one side.

In the embodiment of the present invention, the seal strength of the first weak seal portion 12a is smaller than the seal strength of the second weak seal portion 12b.
In the embodiment of the present invention, the first weak seal portion 12a presses the first drug chamber 3 or the second drug chamber 4 of the container body 82 by hand, and the first drug chamber 3 or the second drug chamber 4 is pressed. The first drug chamber 3 or the second drug chamber 4 portion of the container main body 82 is manually squeezed while the container main body 82 is hung on the hanger. It has a seal strength that can be peeled off by increasing the internal pressure of the drug chamber 3 or the second drug chamber 4. Thereby, the interruption | blocking by the weak seal part 12 for a partition is cancelled | released by simple operation | work, without using a special instrument etc., and the chemical | medical agents of the 1st chemical | medical agent chamber 3 and the 2nd chemical | medical agent chamber 4 can be mixed.
The second weak seal portion 12b is peeled by increasing the internal pressure of the first drug chamber 3 or the second drug chamber 4 to be higher than the peelable internal pressure of the first weak seal portion by the above-described method. The seal strength is as follows. Moreover, the 2nd weak seal | sticker part 12b may be provided with the seal | sticker intensity | strength of the grade which does not peel substantially by pressing the 1st chemical | medical agent chamber 3 or the 2nd chemical | medical agent chamber 4. FIG.

Specifically, the seal strength (initial peel strength) of the first weak seal portion is preferably 0.1 to 5 N / 10 mm, particularly preferably 0.3 to 3 N / 10 mm. If the seal strength is within this range, the first weak seal part will not be accidentally peeled off during transportation or storage, and the work of peeling off the first weak seal part is easy. The seal strength (initial peel strength) of the second weak seal portion is preferably 3N / 10 mm or more, particularly 4N / 10 mm or more.
The seal strength difference (initial peel strength difference) between the first weak seal portion and the second weak seal portion is 3 to 30 N / 10 mm from the seal strength (initial peel strength) of the first weak seal portion, In particular, it is preferably 4 to 25 N / 10 mm larger. In this way, when any one of the drug chambers is pressed, it is possible to suppress the entire weak partitioning portion for partitioning from being peeled at once, and to ensure at least peeling from the first weak sealing portion.
In addition, as a concrete measuring method of seal strength, it can carry out as follows.
Each portion of the container body including the measurement target seal portion is cut into a length of 10 mm in the width direction of the container, and each of the seal strengths obtained by measuring the cut pieces included in the respective seal strength portions at a tensile speed of 300 mm / min. The average value of the part.

  The first weak seal portion can be peeled by pressing the first drug chamber or the second drug chamber, and the second weak seal portion is the first drug chamber or the second drug chamber. It may be one that does not substantially peel by pressing the drug chamber and can be peeled off. Specifically, the first weak seal portion of the container body of the present invention is formed with a seal strength that can be peeled by pressing the first drug chamber or the second drug chamber, and the second weak seal. The part is preferably formed with a seal strength that does not peel off and can be peeled off by pressing the first medicine chamber or the second medicine chamber. By having such a configuration, the first drug chamber swells greatly during the first weak seal portion peeling operation, so that the weak seal for blocking communication can be more reliably peeled off almost simultaneously with the operation. In addition, since the second weak seal portion can be peeled off, the second drug chamber that has not been peeled off can be peeled off with fingers or the like after the weak seal portion for inhibiting communication is peeled off. The medicine inside can be discharged reliably. Further, the scale (not shown) on the bag surface can be read with the same accuracy as that of the single chamber container.

The ratio (La / Lb) of the lateral length (La) of the first weak seal portion 12a to the lateral length (Lb) of the first drug chamber 3 of the container body 82 is 0.2. It is preferable that it is -0.8. In particular, it is preferably 0.3 to 0.7.
The container body 82 has a lateral length (La) of the first weak seal portion 12a with respect to a length (Lc: shortest distance) between the upper end of the communication inhibiting weak seal portion 81 and the upper end of the medicine discharge port. ) Ratio (La / Lc) is preferably 0.2 to 3, more preferably 0.5 to 2. In particular, it is preferably 0.7 to 1.5.
If La / Lc is greater than 0.2, the first weak seal portion is not easily peeled off, and if it is less than 3, the first weak seal portion is peeled off when the first weak seal portion is peeled off. Separation of the seal portion is also ensured. Moreover, it is preferable that the width | variety (band width) of the weak seal part 81 for communication inhibition is 2-20 mm, especially 4-12 mm.

As specific sizes of the container body, for example, the following can be considered.
The inner width of the second drug chamber 4 is 190 mm, the distance between the partition weak seal portion 12 and the upper seal portion 24 is 135 mm, the drug solution (specifically, glucose electrolyte solution) 350 ml filled in the second drug chamber, Filled air amount 60 cc, width (band width) of partition weak seal portion 15 mm, inner width 190 mm of first drug chamber 3, between intermediate portion of partition weak seal portion 12 and inclined portion of lower end side seal portion 22 Distance of 110 mm, drug solution (specifically, amino acid solution) 150 ml filled in the first drug chamber, filled air volume 15 cc, width (band width) 8 mm of communication blocking weak seal portion 81, La 100 mm, Lb 180 mm , Lc 50 mm, reserve capacity (preliminary capacity in a state where the weak seal part is peeled off to form one chamber) 800 ml
The weak seal portion is preferably formed by heat sealing. Specifically, it is preferably performed by a hot press, and the mold temperature can be formed by performing the process at a temperature lower by 10 ° C. or more than the melting temperature of the forming material of the container body 82.

The partition weak seal portion is not limited to the above-described one, and any partition may be used as long as it includes the first weak seal portion and the second weak seal portion that is more difficult to peel off than the first weak seal portion. It may be configured.
As shown in FIG. 44, the partition weak seal portion 12 has a second weak seal portion 12b wider than the first weak seal portion 12a. It may be more difficult to peel off than the first weak seal portion. 44. The partition weak seal portion 12 shown in FIG. 44 is provided at both ends of the narrow band-shaped first weak seal portion 12a, the second weak seal portion 12b provided on both sides thereof, and the partition weak seal portion 12. The strong seal portion 13 is provided. Further, the width of the boundary portion between the first weak seal portion and the second weak seal portion may be gradually narrowed from the second weak seal portion side toward the first weak seal portion side. The seal strength of the first weak seal portion and the seal strength of the second weak seal portion of such a partition weak seal portion are substantially the same or the seal strength of the first seal portion is greater than the seal strength of the second seal portion. It is preferable that it is small.

And the container main body 82 of this invention is provided with the weak seal part 81 for a communication inhibition formed so that the upper direction of the chemical | medical agent discharge port 7 might be surrounded, as shown in FIG. A third chamber 83 isolated from the first medicine chamber 3 is formed by the weak seal portion 81 for inhibiting communication. The third chamber 83 is an empty room. However, a predetermined liquid (for example, physiological saline) may be placed in the third chamber. The third chamber 83 may be in a dry state, but may be filled with a small amount of moisture for sterilization. Furthermore, a passage through which some water vapor or medicine passes through the weak seal portion 81 for inhibiting communication may be formed so as to communicate with the first medicine chamber 3 at the above level. The weak seal portion 81 for inhibiting communication can be formed by heat-sealing the sheet material in a band shape (heat fusion, high frequency fusion, ultrasonic fusion, etc.).
In the embodiment shown in FIG. 43, the weak seal portion 81 for preventing communication is formed in an inverted trapezoidal shape. In addition, the weak seal portion for communication inhibition has a U-shape whose short side is the upper side, a triangular shape whose top is the discharge port, a triangular shape whose bottom is the discharge port, a polygonal shape such as a quadrangle, a substantially semicircular shape, A substantially semi-elliptical shape or an inverted U-shape may be used. In the case of a polygon, the corners are preferably rounded.

Further, as shown in FIG. 43, it is preferable that the communication-inhibiting weak seal portion is provided below the first weak seal portion 12a. By being provided below the first weak seal part, the weak seal part for blocking communication is more easily peeled off more reliably during the partition weak seal part peeling operation.
Moreover, the front-end | tip part of the weak seal part for communication inhibition may become easy to peel from another part. Examples of the distal end portion of such a communication inhibiting weak seal portion 81 include a shape that is recessed toward the discharge port 7 side. With such a configuration, when the first drug chamber or the second drug chamber is pressed, the pressing force is concentrated on the tip portion, so that the weak seal portion for inhibiting communication is easily peeled off. Specifically, the weak seal portion for inhibiting communication is preferably formed so as to be bent or curved toward the discharge port. Moreover, as such a weak seal part 81 for connection inhibition, what the front-end | tip part was formed narrower than the other part is mentioned. Further, the seal strength at the tip may be made smaller than that of other portions.

  Further, the seal strength of the weak seal portion 81 for inhibiting communication is equal to, slightly larger or slightly smaller than the seal strength of the first weak seal portion 12a, and smaller than the seal strength of the second weak seal portion 12b. It is preferable. If it is such, a chemical | medical solution will not be administered in the state in which the 1st weak seal | sticker part does not peel, and administration preparation can be performed by easy operation. In particular, it is preferable that the seal strength of the weak seal portion 81 for inhibiting communication is slightly larger than the seal strength of the first weak seal portion 12a and smaller than the seal strength of the second weak seal portion 12b. Moreover, the weak seal part for communication inhibition presses the 1st chemical | medical agent chamber 3, and the weak seal part 81 for communication inhibition peels substantially simultaneously with or subsequent to peeling of the 1st weak seal part 12a. It is preferable. By doing in this way, the weak seal part 81 for communication inhibition does not peel before the 1st weak seal part 12a.

Further, the container main body is one in which the weak seal portion 81 for preventing communication is peeled by pressing the second drug chamber 4 almost simultaneously with the peeling of the first weak seal portion 12a or following the peeling of the seal portion 12a. It may be. For example, as described above, the weak seal portion 81 for preventing communication has the same seal strength as that of the first weak seal portion or the seal strength of the first weak seal portion 12a. It can be configured by slightly strengthening.
The seal strength (initial peel strength) of the weak seal portion for inhibiting communication is preferably 1 to 25 N / 10 mm, and particularly preferably 2 to 20 N / 10 mm.
Further, when the first drug chamber 3 or the second drug chamber 4 is pressed, the upper end side portion of the weak seal portion 81 for communication inhibition, particularly the upper end portion, is formed in a portion where a strong peeling force is applied. preferable.

In such a container body, the ratio (La / Lc) of the length La of the first weak seal portion 12a to the length (distance) Lc between the upper end of the weak seal portion 81 for inhibiting communication and the upper end of the discharge port 7 is 0.2 to 3 is preferable, and 0.5 to 2 is particularly preferable. With such a configuration, when the first drug chamber 3 or the second drug chamber 4 is pressed, the upper end side portion of the weak seal portion 81 for blocking communication is positioned near a position where a large peeling force is applied. It is considered that the weak seal portion can be easily peeled off.
The length Lc between the upper end of the communication inhibiting weak seal portion 81 and the upper end of the discharge port 7 is a length of a straight line perpendicular to the central axis of the medicine discharge port 7 from the upper end of the communication inhibiting weak seal portion 81. .

In this container main body, when the length La of the first weak seal portion is short in the above-described relationship, the upper end of the communication inhibiting weak seal portion and the upper end of the medicine discharge port are formed as in the container main body 82 shown in FIG. Is short (the length in the vertical direction of the weak seal portion for communication inhibition is short), whereas when the length La of the first weak seal portion is long, the upper end of the weak seal portion for communication inhibition is It is preferable that the length Lc between the upper end of the medicine discharge port and the medicine discharge port is long (the length in the longitudinal direction of the weak seal portion for communication inhibition is long).
A method for forming the partition weak seal portion 12 and the communication blocking weak seal portion 81 is not particularly limited, and can be performed using a heat seal heating mold (heat seal bar) or the like that is normally used. Moreover, you may use the method of producing blocking in the site | part of the weak seal part 12 for a partition and the weak seal part 81 for a communication inhibition at the time of heat sterilization, such as high pressure steam sterilization.

And in the medical container 80 of this embodiment, as shown in FIGS. 41 and 42, in the vicinity of the discharge port 7 of the soft bag 2, the discharge inhibition for inhibiting the external insertion into the discharge port 7d. A member 31 is attached. In this embodiment, the discharge inhibiting member 31 includes the pinching portions 32 and 33 that sandwich the periphery of the discharge port 7 from one surface side and the other surface side of the soft bag 2, and the soft bag by the pinching portions 32 and 33. A holding state holding portion 17 for holding the 2 pinching state, and blocking portions 32b and 33b covering the periphery of the discharge port 7d so as to block the insertion of the discharge port 7 into the discharge port 7d from the outside. Yes. In the illustrated embodiment, the sandwiching portions 32 and 33 sandwich the portion of the soft bag 2 that is slightly closer to the partition weak seal portion side than the communication inhibiting weak seal portion 81 from one surface side and the other surface side. Yes. Note that the sandwiching portions 32 and 33 may sandwich the portion of the soft bag 2 on the discharge port side from the one surface side and the other surface side from the communication inhibiting weak seal portion 81. Further, the sandwiched state holding unit 17 is a weakness for preventing communication due to spreading of the soft bag 2 at the same time as or following the peeling of the partition weak seal portion 12 due to the pressing of the first drug chamber 3 or the second drug chamber 4. Simultaneously with the peeling of the seal portion 81 or slightly before and after, the pinching portions 32 and 33 are released by being spread, and the discharge inhibiting member 31 can be detached from the soft bag 2.
Further, by providing the discharge inhibiting member 31 in such a container main body 82, injection of the chemical solution into the container main body using the discharge port before the separation of the partition weak seal and the communication inhibiting weak seal is prevented. For this reason, only the chemical solution injected into the container main body from the discharge port is safe from being accidentally administered.

FIG. 1 is a front view of a medical container according to an embodiment of the present invention. 2 is a cross-sectional view taken along line AA of the medical container shown in FIG. FIG. 3 is a front view of a communication inhibiting member used in the medical container shown in FIG. FIG. 4 is a side view of the communication inhibiting member shown in FIG. FIG. 5 is an internal view of the communication inhibiting member shown in FIG. FIG. 6 is an explanatory diagram for explaining a method of using the medical container shown in FIG. FIG. 7 is a front view of a medical container according to another embodiment of the present invention. 8 is a cross-sectional view of the medical container shown in FIG. 7 taken along line BB. FIG. 9 is a front view of the discharge inhibiting member used in the medical container shown in FIG. 10 is a side view of the discharge inhibiting member shown in FIG. FIG. 11 is a development view of the discharge inhibiting member shown in FIG. FIG. 12 is an explanatory diagram for explaining a method of using the medical container shown in FIG. FIG. 13 is a front view of a medical container according to another embodiment of the present invention. FIG. 13 is a cross-sectional view of the medical container shown in FIG. FIG. 15 is a front view of a discharge inhibiting member used in the medical container shown in FIG. FIG. 16 is a side view of the discharge inhibiting member shown in FIG. FIG. 17 is a development view of the discharge inhibiting member shown in FIG. FIG. 18 is an explanatory diagram for explaining a method of using the medical container shown in FIG. FIG. 19 is a front view of a medical container according to another embodiment of the present invention. FIG. 20 is a front view of the discharge inhibiting member used in the medical container shown in FIG. FIG. 21 is a side view of the discharge inhibiting member shown in FIG. FIG. 22 is a development view of the discharge inhibiting member shown in FIG. FIG. 23 is a front view of a medical container according to another embodiment of the present invention. 24 is a cross-sectional view of the medical container shown in FIG. FIG. 25 is a front view of the discharge inhibiting member used in the medical container shown in FIG. FIG. 26 is a side view of the discharge inhibiting member shown in FIG. FIG. 27 is a development view of the discharge inhibiting member shown in FIG. FIG. 28 is a front view of the discharge port used in the medical container shown in FIG. 29 is a side view of the discharge port shown in FIG. 30 is a cross-sectional view of the drug container shown in FIG. 28 taken along the line EE. FIG. 31 is a cross-sectional view of the medicine container shown in FIG. 28 taken along the line FF. FIG. 32 is an explanatory diagram for explaining a method of using the medical container shown in FIG. FIG. 33 is a front view of a medical container according to another embodiment of the present invention. 34 is a cross-sectional view of the medical container shown in FIG. 33 taken along the line GG. FIG. 35 is a front view of a communication inhibiting member used in the medical container shown in FIG. Figure 36 is a side view of a communication inhibiting member shown in FIG. 35. FIG. 37 is a development view of the communication inhibiting member shown in FIG. FIG. 38 is an explanatory diagram for explaining a method of using the medical container shown in FIG. FIG. 39 is a front view of another example of the communication inhibiting member used in the medical container of the present invention. Figure 40 is a side view of a communication inhibiting member shown in FIG. 39. FIG. 41 is a front view of a medical container according to another embodiment of the present invention. 42 is a cross-sectional view of the medical container shown in FIG. 41 taken along the line HH. FIG. 43 is a front view of a container body used for the medical container shown in FIG. FIG. 44 is an explanatory diagram for explaining the vicinity of the partition weak seal portion of the medical container according to another embodiment of the present invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Medical container 2 Soft bag 3 1st chemical | medical agent chamber 4 2nd chemical | medical agent chamber 5 1st chemical | medical agent 6 2nd chemical | medical agent 7 Outlet port 12 Weak seal part 14 for partitioning Communication member 15 Narrow pressure part 16 Narrow pressure Part

Claims (13)

A soft bag divided into a first drug chamber and a second drug chamber by a partition weak seal portion from which an internal space can be peeled; a first drug stored in the first drug chamber; A second medicine housed in the second medicine chamber, a discharge port attached to communicate with the first medicine chamber, and communication between the inside of the soft bag and the discharge port attached to the soft bag. A communication blocking member, wherein the communication blocking member narrows the periphery of the discharge port from one side and the other side of the soft bag and discharges the soft bag. A narrow pressure part for inhibiting communication with the port, and a narrow pressure state holding part for holding a narrow pressure state by the narrow pressure part,
Further, the narrow pressure portion includes a first narrow pressure portion and a second narrow pressure portion for narrowing the periphery of the discharge port from one surface and the other surface of the soft bag, The state holding portion is a connecting portion that connects the first narrow pressure portion and the second narrow pressure portion in a state where the narrow pressure state is held, and the connecting portion is the first narrow pressure portion. And a fitting portion provided in the second narrow pressure portion, and the connecting portion includes an insertion path provided in the first narrow pressure portion, and the second insertable in the insertion path. A pin provided in the narrow pressure portion; the first narrow pressure portion and the second narrow pressure portion are closed; and the pin is inserted into the insertion path to be fitted to the first narrow pressure portion. are those parts with narrow pressure state by said second narrow pressure section is maintained, further, the narrow pressure state by a narrow pressure part, the first drug chamber or the second Followed peeling simultaneously to or the release of the partitioning weak seal portion by the pressing of the medicament compartment, wherein the spread of soft bag, between the first of said narrow pressure section second narrow pressure portion is widened, the A medical container which is released when the pin is removed from the insertion path . The communication-inhibiting member includes an encapsulating portion that encapsulates a connection portion side of the discharge port with the soft bag, and the two coupling portions are provided so as to face each other via the encapsulating portion. The medical container according to claim 1. The opening strength of the communication inhibiting member when the first drug chamber or the second drug chamber is pressed is greater than the peel strength of the partition weak seal portion. Medical container. The communication inhibition member includes an inhibition portion that covers the periphery of the discharge port so as to inhibit external insertion of the discharge port into the discharge port, and the communication inhibition member includes the first drug chamber or At the same time as or following the peeling of the weak seal part for partitioning by the pressing of the second drug chamber, the narrow pressure part is pushed and spread by the spread of the soft bag, and the pin comes out of the insertion path. The medical container according to any one of claims 1 to 3 , wherein the medical container is removable from the soft bag. A soft bag divided into a first drug chamber and a second drug chamber by a partition weak seal portion from which an internal space can be peeled; a first drug stored in the first drug chamber; A second medicine housed in the second medicine chamber, a discharge port attached to communicate with the first medicine chamber, and an external insertion to the discharge port of the discharge port attached to the soft bag A discharge-inhibiting member for inhibiting the discharge-inhibiting member, the discharge-inhibiting member comprising a pinching portion sandwiching the periphery of the discharge port from one surface side and the other surface side of the soft bag A pinching state holding portion for holding the pinching state of the soft bag by the pinching portion, and an inhibition portion that covers the periphery of the discharge port so as to inhibit external insertion of the discharge port into the discharge port. Prepared,
The pinching portion includes a first pinching portion and a second pinching portion for pinching the periphery of the discharge port from one surface side and the other surface side of the soft bag, and the pinching state holding portion includes: A connecting portion that connects the first sandwiching portion and the second sandwiching portion while maintaining the sandwiched state, and the connecting portion is provided in the first sandwiching portion and the second sandwiching portion. The connecting portion includes an insertion path provided in the first pinching portion and a pin provided in the second pinching portion that can be inserted into the insertion path, By closing the first sandwiching portion and the second sandwiching portion and inserting the pin into the insertion path and fitting, the sandwiched state between the first sandwiching portion and the second sandwiching portion is maintained. a shall further state sandwiched by the pinching state holding unit, the first drug chamber or the second Followed peeling simultaneously to or the release of the partitioning weak seal portion by the pressing of the agent chamber, by the spread of the soft bag, pushed open between said first pinching portion said second pinching portion is the pin The medical container, which is released by being removed from the insertion path and is capable of removing the blocking member from the soft bag. The medical container according to claim 5, wherein the discharge inhibiting member includes a storage portion that stores the discharge port, and two connection portions are provided so as to face each other via the storage portion. The opening strength of the discharge inhibiting member when the first drug chamber or the second drug chamber is pressed is greater than the peel strength of the partition weak seal portion. Medical container. The connecting portion, according to any one of the soft bags 5 to claim in which coupling is released by being spread with the first pinching portion and the second pinching portion by spreading 7 Medical container. The medical container according to any one of claims 5 to 8 , wherein the soft bag is provided with a communication-inhibiting weak seal portion that inhibits communication between the first drug chamber and the discharge port. The medical weak seal portion according to any one of claims 1 to 9 , wherein the partition weak seal portion includes a first weak seal portion and a second weak seal portion that is less likely to be peeled off than the first weak seal portion. container. The medical container according to claim 1, wherein the blocking member can be attached to a hole provided in the vicinity of the discharge port of the soft bag. The discharge port is made of a hard or semi-rigid material, and has a cylindrical portion whose front end portion is closed and whose rear end portion is sealed so that it can be inserted, and a break provided in at least the front end portion of the cylindrical portion. A first stress applying portion which is provided so as to sandwich the possible portion and the breakable portion of the cylindrical portion and is fixed to one inner surface of the first drug chamber, and the other inner surface of the first drug chamber And the breakable portion breaks due to the spread between the first stress applying portion and the second stress applying portion, and opens the cylindrical portion. The medical container according to any one of claims 1 to 11 , which is a product. The medical container according to claim 12 , wherein a third medicine is accommodated in the cylindrical portion of the discharge port.

Images