JP2508555B2 - Bitterness reduction method - Google Patents
Bitterness reduction methodInfo
- Publication number
- JP2508555B2 JP2508555B2 JP3148077A JP14807791A JP2508555B2 JP 2508555 B2 JP2508555 B2 JP 2508555B2 JP 3148077 A JP3148077 A JP 3148077A JP 14807791 A JP14807791 A JP 14807791A JP 2508555 B2 JP2508555 B2 JP 2508555B2
- Authority
- JP
- Japan
- Prior art keywords
- bitterness
- agent
- jelly
- bitter
- agar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Medicinal Preparation (AREA)
- Jellies, Jams, And Syrups (AREA)
Description
【0001】[0001]
【産業上の利用分野】本発明は医薬品や健康食品等の中
に間々存在する非常に苦くて摂取しにくい物質の苦味を
低減させる方法に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for reducing the bitterness of substances that are present in pharmaceuticals, health foods and the like and are very bitter and difficult to ingest.
【0002】[0002]
【従来の技術】「良薬は口に苦し」とはいうものの、ひ
どく苦い薬は飲みにくく、特にそれが粉末状であったり
すると幼小児や老人には「のどのつかえ」や「むせ」が
起きて服用に困難をきたすことが少なくない。これは最
近出まわっている健康食品でも同じ様に問題になってい
る。2. Description of the Related Art Although it is said that "good medicines are bad for the mouth", it is difficult to take badly bitter medicines, especially when they are in powder form, "child throats" and "sneezing" occur in infants and the elderly. It often causes difficulty in administration. This is just as problematic for the health foods that have recently appeared.
【0003】これらの苦味問題を出来るだけ緩和して、
苦味のある薬等の物質を摂取しやすくする工夫は従来か
ら種々とられてきた。その代表例が錠剤における糖衣や
剤型のカプセル化である。これらは確立された技術であ
って効果には問題がないが、周知のように工程が多く、
又設備にも多額の費用を要する。又、その他の代表的方
法にシロップ化があるが、シロップ化が困難な物質の場
合には採用できない。To alleviate these bitterness problems as much as possible,
Conventionally, various measures have been taken to make it easy to ingest substances such as bitter drugs. Typical examples are sugar coating in tablets and encapsulation of dosage forms. These are established techniques and there is no problem in the effect, but as is well known, there are many steps,
Moreover, a large amount of cost is required for equipment. In addition, other typical methods include syrup formation, but this cannot be used for substances that are difficult to syrup.
【0004】[0004]
【発明が解決しようとする課題】本発明は従来技術に比
べ、より簡便で経済的な苦味のある物質の苦味低減方法
を提供することを課題とするものである。SUMMARY OF THE INVENTION It is an object of the present invention to provide a simpler and economical method for reducing bitterness of a substance having a bitterness as compared with the prior art.
【0005】[0005]
【課題を解決するための手段】本発明者は種々研究の結
果、ゲル化剤を用いてゼリー化し、且つそれに適切な味
付けをすることにより上記課題を解決できることを見出
し本発明を完成した。即ち本発明は、苦味のある物質に
ゲル化剤と味付け剤を添加し味付ゼリー状にすることを
特徴とする苦味低減方法を提供するものである。As a result of various studies, the present inventor has found that the above problems can be solved by gelling with a gelling agent and appropriately seasoning the gelling agent to complete the present invention. That is, the present invention provides a method for reducing bitterness, which comprises adding a gelling agent and a seasoning agent to a substance having bitterness to form a seasoned jelly.
【0006】本発明の方法によれば、苦味低減効果があ
る上に粉末状であるが故の飲みにくさも改善される。本
発明が対象とする苦味のある物質は、医薬品の中で苦味
が問題となるものであり、又、食品、例えば健康食品の
中で苦味があって摂取しにくい物質である。実施例では
タンニン酸、小柴胡湯及び大豆ペプチドの例を示すが、
これらに限定されないことは勿論である。[0006] According to the method of the present invention, in addition to having a bitterness-reducing effect, it is difficult to drink because it is powdery. The bitter substance which is a target of the present invention is a substance in which bitterness is a problem in pharmaceuticals, and is a substance which has a bitter taste and is difficult to ingest in foods such as health foods. Examples show tannic acid, Shosaikoto and soybean peptide,
Of course, it is not limited to these.
【0007】本発明で用いるゲル化剤は寒天、ゼラチ
ン、κ‐カラギーナン等から選ばれる。これらのゲル化
剤を入手するには市販品を購入するのが簡便である。こ
れらゲル化剤の使用量については、苦味物質がタンニン
酸である場合、その0.1g(50ml水溶液)当り、
また小柴胡湯の場合はその2.5g(50ml水溶液)
当り、さらに大豆ペプチドの場合はその50ml当り、
寒天(粉末)は0.1〜0.5g、ゼラチン(粉末)は
1.0〜2.5g、又、κ‐カラギーナンは0.2〜
1.0g、夫々に用いられる。The gelling agent used in the present invention is selected from agar, gelatin, κ-carrageenan and the like. To obtain these gelling agents, it is convenient to purchase a commercial product. Regarding the amount of use of these gelling agents, when the bitter substance is tannic acid, per 0.1 g (50 ml aqueous solution) thereof,
In the case of Shosaikoto, 2.5 g (50 ml aqueous solution)
Per 50 ml of soybean peptide,
0.1 to 0.5 g of agar (powder), 1.0 to 2.5 g of gelatin (powder), and 0.2 to κ-carrageenan.
1.0 g, used for each.
【0008】ゲル化剤の添加量を上記の範囲よりも低減
した場合、苦味軽減効果は低くなり、また、約15分で
ゼリー化しないこともある。逆に、添加量を増加させた
場合には、ゼリー配合剤が均一に溶解せず、溶解不良が
生じたり、ゼリーがかたくなり過ぎ食感が悪くなる。従
って、苦味軽減効果を有し、且つゼリー剤の溶解性が良
く、均一で、表面が平滑で、食感の比較的良いという効
果を有する上記の範囲が好ましい。When the amount of the gelling agent added is less than the above range, the bitterness-reducing effect is low, and the gelling may not occur in about 15 minutes. On the contrary, when the addition amount is increased, the jelly compounding agent is not uniformly dissolved, resulting in poor dissolution or the jelly being too hard and the texture being poor. Therefore, the above range is preferable, which has the effect of reducing bitterness, the solubility of the jelly agent is good, the surface is smooth, and the texture is relatively good.
【0009】本発明において用いられる味付剤はグラニ
ュー糖やココアといった呈味成分の他、必要に応じて香
料や色素も含まれる。このうち呈味成分としては、グラ
ニュー糖等の砂糖類、ブドウ糖、果糖、乳糖、麦芽糖、
水飴、蜂蜜、甘草エキス、ソルビット、マンニット、ス
テビオサイド、サッカリン、アスパルテーム等の甘味類
が主に用いられる他、ココア、コーヒー、濃縮果汁、乳
性飲料等の嗜好飲料類の添加も好ましい。これらのうち
グラニュー糖は分散剤としても有効であり、その添加に
よりゼリー配合剤の溶解性を向上せしめ、均一なゼリー
にするという優れた効果を有している。The flavoring agents used in the present invention include flavoring ingredients such as granulated sugar and cocoa, and if necessary, flavors and pigments. Of these, taste components include sugars such as granulated sugar, glucose, fructose, lactose, maltose,
Sweeteners such as starch syrup, honey, licorice extract, sorbit, mannitol, stevioside, saccharin, aspartame and the like are mainly used, and preference beverages such as cocoa, coffee, concentrated juice and dairy drinks are also preferably added. Of these, granulated sugar is also effective as a dispersant, and the addition thereof improves the solubility of the jelly compounding agent and has an excellent effect of forming a uniform jelly.
【0010】香料としては、パウダーチョコレートのよ
うに食品の着香料として認められているものならいずれ
も使用できる。また、色素も食品用着色料として認めら
れているものの中から選択して使用すれば良い。この味
付剤の配合の一例を示すと、グラニュー糖186.6重
量部、パウダードチョコレート8004(香料)3.0
g、SRチョコレート色NO2(色素)3.0g、ネッ
スルココアPMT16.0gの例があげられる。As the fragrance, any of those recognized as fragrances for foods such as powder chocolate can be used. Further, the dye may be selected from those recognized as food colorants and used. An example of the blending of this seasoning agent is as follows: granulated sugar 186.6 parts by weight, powdered chocolate 8004 (fragrance) 3.0
g, SR chocolate color NO2 (pigment) 3.0 g, and Nestle cocoa PMT 16.0 g.
【0011】味付剤の使用量は、タンニン酸に対しては
その0.1g当り、又小柴胡湯の場合にはその2.5g
当り、さらに大豆ペプチドはその50ml当り夫々に
5.0〜14.0g、用いるのがよい。ゼリー化は、上
記したゲル化剤及び味付剤を苦味物質に混合し、水50
ml(大豆ペプチドは不要)を加えて、寒天の場合には
90〜100℃、ゼラチンの場合には50〜60℃、カ
ラギーナンの場合には70〜80℃の湯にそれぞれ数分
間、攪拌下に温浴させて溶解した後、常温以下に冷却し
て行なう。The amount of the seasoning agent used is 0.1 g for tannic acid and 2.5 g for Shosaikoto.
In addition, it is preferable to use 5.0-14.0 g of soybean peptide per 50 ml. Gelling is carried out by mixing the gelling agent and seasoning agent described above with a bitter substance and adding water 50
Add ml (soybean peptide is not necessary), and add to agitating water for 90 minutes at 90-100 ° C for agar, 50-60 ° C for gelatin and 70-80 ° C for carrageenan. After melting in a warm bath and cooling to room temperature or less, the reaction is performed.
【0012】[0012]
【実施例】以下実施例で本発明を説明する。なお、実施
例中に示す官能テストはパネル人数8人(男4人、女4
人)で行い、評価は++(苦い)、+、±、−、−−
(全く苦味を感じない)で表わした。又、実施例で用い
た味付剤は表1の配合によるチョコレート味付剤であ
る。The present invention will be described in the following examples. In addition, the sensory test shown in the examples was performed by 8 panel members (4 males and 4 females).
Person), and the evaluation is ++ (bitter), +, ±, −, −−
(No bitterness is felt). The seasoning agent used in the examples is a chocolate seasoning agent having the composition shown in Table 1.
【0013】[0013]
【表1】 [Table 1]
【0014】実施例1(タンニン酸の苦味低減) (1)タンニン酸(岩井化学薬品製、以下同じ)0.0
5gを水25mlに溶解する。これを官能テストの対照
例とした。Example 1 (Reduction of bitterness of tannic acid) (1) Tannic acid (manufactured by Iwai Chemical Co., Ltd., hereinafter the same) 0.0
Dissolve 5 g in 25 ml water. This was used as a control example of the sensory test.
【0015】(2)ゲル化剤を寒天にした場合 タンニン酸0.05gに粉末寒天(イナ寒天製、以下同
じ)0.25gとチョコレート味付剤(表1の場合のも
の、以下同じ)5.22gを加え、よく混合した後、水
25mlを加える。これを90〜100℃の温浴中、攪
拌しながら溶解せしめた後、冷蔵庫中で冷却しゼリー化
した。このものの官能テストの結果を表2に示す。(2) When agar is used as the gelling agent: 0.05 g of tannic acid, 0.25 g of powdered agar (manufactured by Ina Agar, the same applies hereinafter) and chocolate flavoring agent (in the case of Table 1, the same applies below) 5 Add .22 g and mix well, then add 25 ml water. This was dissolved in a hot bath at 90 to 100 ° C with stirring and then cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 2.
【0016】(3)ゲル化剤をゼラチンにした場合 タンニン酸0.05gに粉末ゼラチン(ニッピ製、以下
同じ)1.25gとチョコレート味付剤5.22gを加
え、よく混合した後、水25mlを加える。これを50
〜60℃の温浴中、攪拌しながら溶解せしめた後、冷蔵
庫中で冷却しゼリー化した。このものの官能テストの結
果を表2に示す。(3) When gelatin is used as gelling agent: To 0.05 g of tannic acid, 1.25 g of powdered gelatin (manufactured by Nippi, the same applies below) and 5.22 g of chocolate flavoring agent were added, mixed well, and then 25 ml of water. Add. This is 50
The mixture was dissolved in a warm bath of -60 ° C with stirring and then cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 2.
【0017】(4)ゲル化剤をκ‐カラギーナンにした
場合 タンニン酸0.05gにκ‐カラギーナン(中央化成
製、以下同じ)0.38gとチョコレート味付剤5.2
2gを加え、よく混合した後、水25mlを加える。こ
れを70〜80℃の温浴中、攪拌しながら溶解せしめた
後、冷蔵庫中で冷却しゼリー化した。このものの官能テ
ストの結果を表2に示す。(4) When κ-carrageenan is used as a gelling agent: 0.05 g of tannic acid, 0.38 g of κ-carrageenan (manufactured by Chuo Kasei, the same applies hereinafter) and a chocolate flavoring agent 5.2.
After adding 2 g and mixing well, 25 ml of water is added. This was dissolved in a hot bath at 70 to 80 ° C with stirring and then cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 2.
【0018】[0018]
【表2】 [Table 2]
【0019】実施例2(小柴胡湯の苦味低減) (1)小柴胡湯(ツムラ製、以下同じ)1.25gを水
25mlに溶解する。これを官能テストの対照例とした。Example 2 (Reduction of bitterness of Shosaikoto) (1) 1.25 g of Shosaikoto (manufactured by Tsumura, the same applies hereinafter) is dissolved in 25 ml of water. This was used as a control example of the sensory test.
【0020】(2)ゲル化剤を寒天にした場合 小柴胡湯1.25gに粉末寒天0.25gとチョコレー
ト味付剤5.22gを加え、よく混合した後、水25m
lを加える。これを90〜100℃の温浴中、攪拌しな
がら溶解せしめた後、冷蔵庫中で冷却しゼリー化した。
このものの官能テストの結果を表3に示す。(2) When agar was used as the gelling agent: To 1.25 g of Shosaikoto, 0.25 g of powdered agar and 5.22 g of the chocolate seasoning agent were added, mixed well, and then 25 m of water.
Add l. This was dissolved in a hot bath at 90 to 100 ° C with stirring and then cooled in a refrigerator to form a jelly.
The results of the sensory test of this product are shown in Table 3.
【0021】(3)ゲル化剤をゼラチンにした場合 小柴胡湯1.25gに粉末ゼラチン1.25gとチョコ
レート味付剤5.22gを加え、よく混合した後、水2
5mlを加える。これを50〜60℃の温浴中、攪拌し
ながら溶解せしめた後、冷蔵庫中で冷却しゼリー化し
た。このものの官能テストの結果を表3に示す。(3) When gelatin is used as gelling agent 1.25 g of Shosaikoto is added with 1.25 g of powdered gelatin and 5.22 g of chocolate flavoring agent and mixed well, followed by water 2
Add 5 ml. This was dissolved in a warm bath of 50 to 60 ° C with stirring and then cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 3.
【0022】(4)ゲル化剤をκ‐カラギーナンにした
場合 小柴胡湯1.25gにκ‐カラギーナン0.38gとチ
ョコレート味付剤5.22gを加え、よく混合した後、
水25mlを加える。これを70〜80℃の温浴中、攪
拌しながら溶解せしめた後、冷蔵庫中で冷却しゼリー化
した。このものの官能テストの結果を表3に示す。(4) When κ-carrageenan was used as the gelling agent: To 1.25 g of Shosaikoto, 0.38 g of κ-carrageenan and 5.22 g of the chocolate seasoning agent were added and mixed well,
Add 25 ml of water. This was dissolved in a hot bath at 70 to 80 ° C with stirring and then cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 3.
【0023】[0023]
【表3】 [Table 3]
【0024】実施例3(大豆ペプチドの苦味低減) 大豆ペプチドは、豆乳500mlを55℃、30分間イ
ンキュベートし、それに0.25gの酵素液(半井化学
製、ブロメライン0.05%溶液)を加え、さらに55
℃で90分間インキュベートして調製した。 (1)この大豆ペプチド25mlを対照例とする。Example 3 (Reduction of Bitterness of Soybean Peptide) For soybean peptide, 500 ml of soy milk was incubated at 55 ° C. for 30 minutes, and 0.25 g of enzyme solution (manufactured by Hanai Chemical Co., Ltd., Bromelain 0.05% solution) was added thereto, 55 more
It was prepared by incubating at 90 ° C. for 90 minutes. (1) 25 ml of this soybean peptide is used as a control.
【0025】(2)ゲル化剤を寒天にした場合 大豆ペプチド25mlに粉末寒天0.25gとチョコレ
ート味付剤5.22gを加え、よく混合した寒天及び味
付剤を90〜100℃の温浴中、攪拌しながら溶解せし
めた後、冷蔵庫中で冷却しゼリー化した。このものの官
能テストの結果を表4に示す。(2) When agar is used as the gelling agent: To 25 ml of soybean peptide, 0.25 g of powdered agar and 5.22 g of chocolate flavoring agent were added, and the agar and flavoring agent were mixed well in a hot bath at 90 to 100 ° C. After dissolving with stirring, the mixture was cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 4.
【0026】(3)ゲル化剤をκ‐カラギーナンにした
場合 大豆ペプチド25mlにκ‐カラギーナン0.38gと
チョコレート味付剤5.22gを加え、よく混合したカ
ラギーナン及び味付剤を70〜80℃の温浴中、攪拌し
ながら溶解せしめた後、冷蔵庫中で冷却しゼリー化し
た。このものの官能テストの結果を表4に示す。(3) When κ-carrageenan is used as the gelling agent: To 25 ml of soybean peptide, 0.38 g of κ-carrageenan and 5.22 g of a chocolate flavoring agent were added, and the well mixed carrageenan and flavoring agent were mixed at 70 to 80 ° C. After being dissolved in the warm bath of 1 while stirring, the mixture was cooled in a refrigerator to form a jelly. The results of the sensory test of this product are shown in Table 4.
【0027】[0027]
【表4】 [Table 4]
【0027】表2〜表4の官能テストの結果にみるよう
に、全員苦味を感じていた苦味物質が本発明の味付ゼリ
ーにすることによって、ほとんど苦味を感じないように
なることがわかる。このように効果のあがった理由は確
認されていないが、苦味物質が口中に広まることなく摂
取が可能となったこととマスキング効果が相乗されたこ
とによるものと考えている。As can be seen from the results of the sensory tests in Tables 2 to 4, it is found that the bitter substances which all had a bitter taste are hardly bitter when the seasoned jelly of the present invention is used. The reason why the effect was improved in this way has not been confirmed, but it is considered that the masking effect is synergized with the fact that the bitter substance can be ingested without spreading in the mouth.
【0028】[0028]
【発明の効果】本発明には、苦くて服用或いは摂取がし
にくかった物質の苦味が大巾に軽減されるという効果と
ともに、それが粉末状である場合「のどのつかえ」や
「むせ」が起きて、幼小児、老人等にとって摂取が極め
て困難であったものを容易にするという優れた効果があ
る。また、味付を工夫すれば嗜好品化することも可能で
ある。INDUSTRIAL APPLICABILITY The present invention has the effect of greatly reducing the bitterness of substances that are bitter and difficult to take or ingest, and when it is in the form of powder, it can be used to It has an excellent effect of waking up and facilitating something that was extremely difficult to ingest for infants and the elderly. It is also possible to make it into a favorite product by devising the seasoning.
Claims (2)
添加し味付ゼリー状にすることを特徴とする苦味低減方
法。1. A method for reducing bitterness, which comprises adding a gelling agent and a seasoning agent to a substance having bitterness to form a seasoned jelly.
ーナンから選ばれたものである請求項1記載の苦味低減
方法。2. The method for reducing bitterness according to claim 1, wherein the gelling agent is selected from agar, gelatin and κ-carrageenan.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3148077A JP2508555B2 (en) | 1991-05-24 | 1991-05-24 | Bitterness reduction method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3148077A JP2508555B2 (en) | 1991-05-24 | 1991-05-24 | Bitterness reduction method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH04346937A JPH04346937A (en) | 1992-12-02 |
JP2508555B2 true JP2508555B2 (en) | 1996-06-19 |
Family
ID=15444710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3148077A Expired - Lifetime JP2508555B2 (en) | 1991-05-24 | 1991-05-24 | Bitterness reduction method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2508555B2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE342735T1 (en) * | 1997-03-28 | 2006-11-15 | Eisai Co Ltd | ORAL PHARMACEUTICAL COMPOSITIONS WITH REDUCED BITTERNESS THROUGH FLAVOR SCAMMERS |
JP4555407B2 (en) * | 1998-05-06 | 2010-09-29 | 伊那食品工業株式会社 | Kampo medicines and herbal medicines |
EP1210880B8 (en) * | 1998-10-28 | 2009-06-03 | San-Ei Gen F.F.I., Inc. | Compositions containing sucralose and application thereof |
JP2001226293A (en) * | 2000-02-17 | 2001-08-21 | Kotaro Kanpo Seiyaku Kk | Taking assisting agent |
ATE437632T1 (en) | 2000-03-01 | 2009-08-15 | Eisai R&D Man Co Ltd | RAPID DISRUPTING POLYVINYL TABLET |
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JP5918584B2 (en) * | 2012-03-23 | 2016-05-18 | 杏林製薬株式会社 | Taste masking method |
CN109965018B (en) * | 2017-12-28 | 2022-03-18 | 长沙理工大学 | Production method of bitter-free red bean and coix seed beverage |
WO2019155955A1 (en) * | 2018-02-09 | 2019-08-15 | サントリーホールディングス株式会社 | Liquid composition for oral use containing collagen peptide, and method for improving flavor of liquid composition for oral use including collagen peptide |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5697220A (en) * | 1979-12-28 | 1981-08-05 | Shinichi Hoshino | Preliminarily dosed medicine preparation |
JPS6049751A (en) * | 1983-08-29 | 1985-03-19 | Ajinomoto Co Inc | Food composition |
JPH0262831A (en) * | 1988-08-26 | 1990-03-02 | Fuji Kapuseru Kk | Soft gel |
-
1991
- 1991-05-24 JP JP3148077A patent/JP2508555B2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5697220A (en) * | 1979-12-28 | 1981-08-05 | Shinichi Hoshino | Preliminarily dosed medicine preparation |
JPS6049751A (en) * | 1983-08-29 | 1985-03-19 | Ajinomoto Co Inc | Food composition |
JPH0262831A (en) * | 1988-08-26 | 1990-03-02 | Fuji Kapuseru Kk | Soft gel |
Also Published As
Publication number | Publication date |
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JPH04346937A (en) | 1992-12-02 |
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