JP2589439B2 - Propolis composition for food and method for producing the same - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a propolis composition having excellent dispersibility in water and useful as a health food or the like and a method for producing the same.

[0002]

2. Description of the Related Art Propolis is a resinous substance collected from a honeycomb and contains flavonoids, organic acids such as P-coumaric acid and cinnamic acid and esters thereof, various minerals, vitamins and the like. It is known that it has an antibacterial action, an antioxidant action, an anticancer action and an antiaging effect. Although the active ingredients of these propolis are hardly soluble in water, many of them are soluble in organic solvents, so products containing propolis,
That is, ethanol extract of propolis is used for health foods, pharmaceuticals, and cosmetics.

[0003]

However, as described above, most of the components of propolis, including flavonoids, are almost insoluble in water, so that various inconveniences occur when processing or using propolis products. I have. For example,
In producing a drink containing propolis, when a propolis extract is added to an aqueous solution containing other drink ingredients, some of the insoluble components precipitate out as oil. This oily substance not only contaminates equipment and containers and hinders the manufacturing operation, but also reduces the product yield because the precipitated oily component contains a large amount of active ingredients, and reduces the product quality. Come down.

An ethanol extract of propolis is sold as it is as a health food. In this case, the ethanol extract is diluted with water or fruit juice and taken, but not only does the insoluble active ingredient contained in the propolis precipitate in oil, which significantly impairs the image of the product, and also contaminates the container, Or adhere to teeth. Since this deposit cannot be easily removed by washing, it is a problem in using the product.

[0005] The prior art relating to a propolis composition having dispersibility in water and a method for producing the same is disclosed in Japanese Patent Application Laid-open No. Hei 2-
There is a technique described in Japanese Patent No. 245159 (name: propolis food composition and a method for producing the same, hereinafter referred to as a prior patent). Claim 1 of this prior patent discloses "a propolis food composition comprising a monohydric alcohol extract of propolis, a polyol such as glycerin, and a polyol / fatty acid surfactant". Claim 2 of the preceding patent discloses a method for producing the propolis food composition of claim 1.

[0006] The only monohydric alcohol that can be used for food is ethanol, and polyols such as glycerin include sugars and sugar alcohols. The polyol / fatty acid surfactant is a food additive of a chemically synthesized product, and is not suitable for the propolis market for health foods, pharmaceuticals, and cosmetics.

On the other hand, in the conventional product, sucrose,
A production method for removing ethanol from a propolis composition containing a sugar such as glucose or a sugar alcohol such as sorbitol or reduced starch syrup has not been established. For example, in the composition using a polyol / fatty acid-based surfactant as the surfactant component according to the method of Example 1 of the prior patent specification, the propolis component in the concentrate, the saccharide and the sugar alcohol are separated at the stage of removing ethanol. Therefore, a uniform propolis composition cannot be obtained.

In the prior art, no technique has been established for producing a water-dispersible propolis composition in which components contained in a propolis raw material are emulsified or colloided as they are without using a chemically synthesized product. For example, claim 3 of the prior patent
The food composition of the present invention contains multiple hydrogen bonding
Since the dissolving power of the H-based medium is lower than that of ethanol,
A significant portion of the propolis active ingredient is missing.

[0009] The present invention was made in view of the above problems, the first object, propolis extract
Distillate is undissolved, yet to provide a food propolis composition and a method of manufacturing the same having excellent dispersibility in water, thereby upon water dilution of food propolis composition, insoluble in water An object of the present invention is to solve the inconvenience in producing a propolis product or using a propolis product due to the precipitation of a component as an oil.

[0010] A second object of the present invention is to provide health foods and pharmaceuticals.
Becomes more preferred material as goods material, and the active ingredient of propolis ingredients directly contained without alteration, good stability, and good food for professional <br/> Indianapolis composition of yield and high quality It is to provide a manufacturing method.

[0011]

Means for Solving the Problems To achieve the above object, a propolis composition for food of the first invention contains a propolis extract , ethanol and Quillajasaponin.
It is a liquid . Propolis for food of the second invention
The method for producing the composition is based on the propolis substance or propolis extraction.
Add ethanol and quillaja saponin to the product
Preparing a food propolis composition comprising:
Is what you do . Propolis composition for food of the third invention
Is manufactured by adding ethanol to the propolis ethanol extract.
Propolis composition for food in the form of a solution by adding saponin
The method is characterized by preparing a product .

[0012]

The propolis extract in the present invention includes both a solution containing an extraction solvent, and a solid or powder from which the solvent has been removed. In the case of a solution, the concentration of propolis is preferably 70% by weight or less in view of viscosity, and in the case of propolis tincture (alcohol solution of propolis) used as a health food, it is usually preferably 10 to 20% by weight.

[0014] The solvent used in this invention, solvents compatible with water rather preferably, ethanol is used. sand
KazuSatoshi, and to its preparation propolis composition for food ethanol is most suitable.

[0015] Saponins for use in this invention has a function of lowering the interfacial tension, and some of such activity
And Kirayasaponin is used . Generally, saponin refers to glycosides distributed in plants, and is composed of a hydrophobic aglycone and a hydrophilic sugar moiety. The saponin is not a material as a mere detergent, that has become a functional food material having efficacy as health food. Quiryasaponin is suitable for the propolis composition for food and its production. If met requirements as a surfactant, Kira
The purity of the Ya saponin is not particularly defined. For example, in the case of Kirayasaponin, Kirayasa in commercially available Kiraya extract
Products having a ponin content of 25% by weight or 5% by weight can be used as they are.

[0016] In this invention, the amount of Quillaja saponin, Quillaja saponin, type of propolis extract varies depending on the concentration, the normal propolis composition, at least 0.01% by weight Quillaja saponin solids It is used in tincture products at 1 to 10% by weight.

[0017]

[0018]

[0019] to the next, a method for manufacturing of food propolis composition.

[0020] In the production method of the second invention, propoxycarbonyl
Ethanol and Kiraya in squirrel drug substance or propolis extract
By adding saponin, the solution
A squirrel composition is obtained. Further, in the manufacturing method of the third invention,
In the case of the propolis ethanol extract,
By adding nin, the solution of food-grade propolis
A composition is obtained . In these ways, Quillaja saponin
Thereby , the extraction efficiency of the active ingredient from the propolis body can be improved.

The propolis composition of the present invention can be concentrated , for example, by using a rotary evaporator under reduced pressure .
As a result, the content of ethanol is low or no ethanol is contained.

[0022] In this case, the surfactant for operation of the Quillaja saponin
Is expressed. That is, the active ingredient of the raw material propolis can be made into a solution without deteriorating, and there is no possibility of separation during the concentration, so that there is no generation of tar, and therefore the concentration is performed smoothly.

In addition, in order to lower the ethanol content in the propolis composition, it is effective to add water during the concentration. This is because the water forms an azeotropic mixture with ethanol, and the ethanol can be reliably distilled off.

[0024]

The propolis composition for foods of the first invention exhibits excellent dispersibility in water since the contained quillajasaponin exhibits excellent surfactant activity. In addition, by using a Quillaja saponin, field
The surface activity is effectively exhibited, and the effect as a health food is obtained .

[0025] In the method for producing a propolis composition for food according to the second invention , the propolis substance or propolis extraction is performed.
By adding ethanol and Quillaya saponin
Thus, a propolis composition for food in a solution form is obtained. Ma
Further, in the method for producing the propolis composition for food according to the third invention,
In the case of the propolis ethanol extract,
By adding nin, the solution of food-grade propolis
A composition is obtained. According to these methods, the extraction efficiency of the active ingredient is improved by using Quillajasaponin having a surfactant activity with ethanol, and the method is described in Example 3 described later.
As shown, no oily components were precipitated during the manufacturing process.
Good, uniform and excellent products can be obtained .

By concentrating the propolis composition of the present invention under reduced pressure using , for example, a rotary evaporator, a propolis composition can be obtained. At this time, Quillaja service <br/> can for surfactants operation of Ponin Therefore into solution without changing the nature of the active ingredient of the raw material propolis, no fear of causing separation during concentration, concentration is carried out smoothly. Then, a propolis composition having a low ethanol content or containing no ethanol is obtained.

[0027]

【Example】

(Example 1) 1 kg of Brazilian propolis raw mass was pulverized,
To this was added 2 kg of 95% ethanol, and the mixture was allowed to stand at room temperature for one week with occasional stirring. 2 Separated by filtration through filter paper to obtain a propolis extract. 200 g of Kirayanin C-100 (manufactured by Maruzen Kasei Co., Ltd., containing 25% of Kiraya extract) was added to this propolis extract.
After stirring, the mixture was filtered again, and ethanol was added to adjust the concentration to 20% as a solid content derived from propolis to obtain 2 kg of a tincture-type propolis composition.

The appearance of this propolis composition is the same as ordinary propolis ethanol tincture, and is a brown transparent liquid, which is easily dispersed in water. (Example 2) 9 kg of Chinese raw propolis ingot was crushed and
36 liters of ethanol was added, and the mixture was left at room temperature for one week with occasional stirring. The supernatant was no. 2 To the filtrate separated by filtration through filter paper was added 2 kg of Kirayanin C-100. After stirring, the mixture was filtered again, and then concentrated under reduced pressure using a rotary evaporator, and the concentration was adjusted to 50% as a solid derived from propolis to obtain 8.1 kg of a concentrate.

20 g of this propolis composition was added to 1 kg of reduced starch syrup S30 (manufactured by Niken Kagaku Co., Ltd.) with stirring. The mixture was stirred at 24,000 rpm for 10 minutes at room temperature using an emulsifier (Ultra Disperser, manufactured by Yamato Scientific Co., Ltd.) to obtain 1.0 kg of an emulsion-type propolis composition.

The emulsion of the propolis composition was stable even when stored for a long period of time. (Example 3) 1 kg of propolis raw mass from Brazil was pulverized,
After adding 2 kg of ethanol and 100 g of Kirayanin C-100, the mixture was allowed to stand at room temperature for one week with occasional stirring. 2 Separated by filtration with filter paper. Then, the concentration was adjusted to 20% as a propolis-derived solid content to obtain 2.2 kg of a tincture-type propolis composition.

In the production process of this propolis composition, the extraction efficiency, that is, the yield, was improved by 10% (0.2 kg) as compared with Example 1 due to the addition of Kirayanin C-100 to ethanol in advance.

To 100 g of the propolis composition, 1 kg of fructose-glucose liquid sugar (concentration: 75%) was added with stirring. 24000 at room temperature with the Ultra Disperser
The mixture was stirred at rpm for 10 minutes to obtain 1.05 kg of an emulsion type propolis composition.

To 1 kg of this propolis composition was added 100 g of soybean saponin (soybean extract manufactured by Koshiro Pharmaceutical Co., Ltd.), and then dispersed in 500 kg of water. To this, 1.5 kg of citric acid, 100 kg of honey and 500 g of ginseng extract (containing ginseng saponin) were added and stirred. Thereafter, the mixture was filtered through a 200-mesh strainer, and then dispensed into glass bottles in 50 ml portions while sterilizing by heating at 90 ° C. for 10 minutes to obtain 10,000 drinks of the propolis composition.

In the production process, no oily component was precipitated, and the dispersion of the emulsion was good, so that it was easy to dispense, and a uniform and excellent product was obtained .

[0035]

( Comparative Example 1) Using raw propolis raw material from Brazil as a raw material, 100 g of propolis extract having a solid content concentration of 20% derived from propolis prepared by the method of Example 1 was mixed with Ryoto Sugar Ester S-1670 (distributor) 2.5 g of sucrose fatty acid ester (Mitsubishi Chemical) was added, but the sucrose fatty acid ester hardly dissolved. When this was stirred and the sucrose fatty acid ester was suspended and poured into water, a large amount of oil component was precipitated. (Comparative Example 2) 24.5% of solid content derived from propolis prepared in Example 4
To 100 g of the propolis extract, 2.5 g of Ryoto Sugar Ester S-570 (sucrose fatty acid ester of Mitsubishi Kasei Co., Ltd.) and 1 kg of water were added and stirred. It was subjected to vacuum concentration using a rotary et bar porator added 1.07kg reduced starch syrup SE 30 thereto, middle propolis components and reduced starch syrup components of the concentrate are separated and a uniform and separation component temperature falls solidifies No concentrate was obtained.

As described above, a commercially available propolis extract, when poured into water, precipitates a large amount of oily components, which not only greatly impairs the image of the product, but is unsuitable as a raw material for drink products and the like. On the other hand, according to the present invention, a solution-type propolis composition can be easily produced, and the conventional problems can be completely solved by the propolis composition. The fact that these effects cannot be obtained by the conventional technique is apparent from the propolis compositions of Example 1 and Comparative Example 1 and the results of their production.

According to the present invention, a propolis composition having good dispersibility in water and containing a chemically synthesized product such as a polyol / fatty acid ester, unlike the prior art emulsified propolis composition of the prior art. A propolis composition having an ideal composition as a healthy food is provided.

[0039]

[0040] The present invention is not said to be limited to embodiments, for example, from the addition of Quillaja Saponi <br/> on to propolis extract and stirred to extract the active ingredient in propolis drug substance The configuration may be arbitrarily changed and embodied without departing from the spirit of the present invention.

[0041]

As described in detail above, the food of the first invention
The propolis composition for use has an excellent effect of exhibiting good dispersibility in water based on the surface-active action of quillajasaponin . Further, Quillaja Saponi Ri by <br/> in emissions, surface activity is exhibited effectively, moreover Ru excellent effect that it is preferable to obtain as a health food.

[0042] According to the manufacturing method of the second and food propolis composition of the third invention, the Quillaja saponin with ethanol and surface activity, thereby improving the extraction efficiency of the active ingredient in Puropori scan, the manufacturing process Oil in
An excellent effect that precipitation of components can be prevented is exhibited.

[0043] Further, according to the manufacturing method of food propolis composition, or ethanol content is low, or propolis composition without ethanol, thus the raw material for field <br/> surfactant operation of Quillaja Saponi down A high-quality, stable food that can be made into a solution without deteriorating the active ingredients of the propolis, without causing separation during the concentration process.
An excellent effect that a propolis composition for use can be obtained with high yield.

Therefore, the propolis composition of the present invention
Since the materials used are all safe and functional materials, they are particularly useful as health foods, pharmaceuticals, cosmetics and the like.

Claims (3)

(57) [Claims] 1. Propolis extract , ethanol and giraffe
A propolis composition for food containing yasaponin and in the form of a solution . 2. A propolis substance or propolis extract
Add ethanol and quillaja saponin to form a solution
A food characterized by preparing a propolis composition for food
A method for producing a propolis composition for articles. 3. An ethanol extract of propolis is prepared with Kiraya.
Propolis composition for food in the form of a solution by adding saponin
Propolis composition for food characterized by preparing a product
Manufacturing method.