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JP2006087748A - Instrument for measuring optical property of skin - Google Patents

Instrument for measuring optical property of skin Download PDF

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JP2006087748A
JP2006087748A JP2004278499A JP2004278499A JP2006087748A JP 2006087748 A JP2006087748 A JP 2006087748A JP 2004278499 A JP2004278499 A JP 2004278499A JP 2004278499 A JP2004278499 A JP 2004278499A JP 2006087748 A JP2006087748 A JP 2006087748A
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JP4517800B2 (en
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Osatoshi Yoneda
修敏 米田
Nobutoshi Kojima
伸俊 小島
Shuichi Akasaki
秀一 赤崎
Toshiaki Iwai
俊昭 岩井
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Kao Corp
Hokkaido University NUC
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Hokkaido University NUC
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Abstract

<P>PROBLEM TO BE SOLVED: To instantaneously change illumination light to be used for measuring transparency and color information on the skin so as to be able to measure the transparency and the color information nearly simultaneously and to associate the transparency and the color information measured with the impression of the appearance of the skin. <P>SOLUTION: The subject instrument for measuring the optical properties of the skin is equipped with (A), (B) and (C). Here, (A) is an irradiating means capable of continuously changing a converging light and a parallel light and irradiating a skin surface in non-contact way, (B) is a transparency measuring means to detect a reflected light of the converging light cast to the skin and compute a damping coefficient (μ<SB>eff</SB>), an absorption coefficient (μ<SB>a</SB>) or an equivalent scattering coefficient (μ<SB>s</SB>'), and (C) is a color measuring means to detect the reflected light of the parallel light cast to the skin and to measure the color information. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は、皮膚外観の印象を、皮膚の透明性や色情報という光学的な計測値に基づいて表すことのできる計測装置に関する。   The present invention relates to a measuring device that can express an impression of skin appearance based on optical measurement values such as skin transparency and color information.

皮膚外観の印象は、皮膚の透明性(内部散乱状態)と、基調となる肌色、シミ、クマ等の色情報に大きく依存する。   The impression of the appearance of the skin largely depends on the transparency of the skin (internal scattering state) and the color information such as the skin color, stains, and bears that are the basic tone.

物体の透明性の計測方法としては、一般に、VRM(ビデオレフレクトメトリー)が知られている。これは物体表面にレーザーや白色光等種々の光を集光照射し、その内部散乱光の後方反射量を計測するものであり、透明性の高い物体ほど集光点近傍での光反射(内部散乱光の後方反射)の範囲が大きくなる。   VRM (video reflectometry) is generally known as a method for measuring the transparency of an object. This is to collect and irradiate various light such as laser and white light on the object surface and measure the amount of back reflection of the internally scattered light. The more transparent object, the light reflection near the condensing point (internal The range of back reflection of scattered light is increased.

また、皮膚のように、散乱性の強い物体の透過散乱光を検出し、その内部情報を非破壊的に測定する装置として光CT等の装置が知られており、そのような装置において、試料の深さ方向の情報を得られるようにしたものも提案されている(特許文献1)。   Also, a device such as optical CT is known as a device for detecting transmitted scattered light of a strongly scattering object such as skin and measuring the internal information nondestructively. There has also been proposed one that can obtain information in the depth direction of the above (Patent Document 1).

一方、光沢量や色情報(L*a*b*等)の計測や解析は、集光手段を用いずに皮膚の一定面積を照明し、その反射光を検出することによりなされている。また、その画像のRGBの強度ベクトルを成分分析することにより、メラニン成分量、ヘモグロビン成分量等を求めることがなされている(特許文献2)。 On the other hand, measurement and analysis of gloss amount and color information (L * a * b *, etc.) are performed by illuminating a certain area of the skin without using a light collecting means and detecting the reflected light. In addition, the melanin component amount, the hemoglobin component amount, and the like are obtained by component analysis of the RGB intensity vectors of the image (Patent Document 2).

特開平10−82732号公報JP-A-10-82732 特開2002−200050号公報JP 2002-200050 A

皮膚外観の印象を左右するファクターとして皮膚の透明性と色情報を計測する場合、皮膚は外的環境や心理的環境の変化により血流量が変化しやすいため、それらは同時に計測することが望ましい。しかしながら、これまでの装置では透明性と色情報を同時に計測することができない。   When measuring skin transparency and color information as factors that affect the appearance of the skin, it is desirable to measure them simultaneously because the blood flow is likely to change due to changes in the external environment and psychological environment. However, conventional devices cannot measure transparency and color information at the same time.

これに対し、本発明は、皮膚の透明性と色情報をほぼ同時に計測できるようにすること、さらに、そのようにして計測された透明性と色情報を、皮膚の外観の印象と関連づけ、皮膚外観の印象を透明性と色情報を用いて客観的数値として表わせるようにすることを目的とする。   On the other hand, the present invention makes it possible to measure the transparency and color information of the skin almost simultaneously, and further associates the transparency and color information thus measured with the impression of the appearance of the skin, The objective is to be able to express the impression of appearance as an objective numerical value using transparency and color information.

本発明者らは、上述の目的を達成するためには、皮膚からの反射光を検出して解析する装置に、皮膚に非接触に集光光と平行光を連続的に切り替え照射することのできる照射手段を設けることが有効であること、さらに透明性の指標として、例えば減衰係数を使用し、これと色情報とを皮膚外観の印象スコアに対して重回帰分析した場合に、減衰係数と色情報をほぼ同時に計測すると、これらと印象スコアとにきわめて高い相関性を得られることを見出した。   In order to achieve the above-mentioned object, the present inventors continuously switch and irradiate the apparatus for detecting and analyzing the reflected light from the skin with the condensed light and the parallel light without contact with the skin. It is effective to provide an irradiating means that can be used. Further, as an index of transparency, for example, an attenuation coefficient is used, and when this and color information are subjected to multiple regression analysis on the impression score of the skin appearance, It was found that when color information was measured almost simultaneously, an extremely high correlation was obtained between these and the impression score.

即ち、本発明は、(A)、(B)及び(C):
(A)皮膚表面に非接触に集光光と平行光を連続的に切り替え照射することのできる照射手段、
(B)皮膚に照射した集光光の反射光を検出し、減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')を算出する透明性計測手段、
(C)皮膚に照射した平行光の反射光を検出し、色情報を計測する測色手段
を備えた皮膚の光学的性状の計測装置を提供する。
That is, the present invention provides (A), (B) and (C):
(A) Irradiation means capable of continuously switching and irradiating condensed light and parallel light in a non-contact manner on the skin surface;
(B) a transparency measuring means for detecting reflected light of the condensed light irradiated on the skin and calculating an attenuation coefficient (μ eff ), an absorption coefficient (μ a ), or an equivalent scattering coefficient (μ s ′);
(C) Provided is a measuring device for optical properties of skin, comprising colorimetric means for detecting reflected light of parallel light irradiated on the skin and measuring color information.

特に、この計測装置において、前記色情報からメラニン量とヘモグロビン量を算出し、ヘモグロビン量、メラニン量及び減衰係数(μeff)と皮膚外観の印象スコアとの回帰式に基づき、任意の被験者のヘモグロビン量、メラニン量及び減衰係数(μeff)から該被験者の皮膚外観の印象スコアを出力する演算手段を備えた態様を提供する。 In particular, in this measuring apparatus, the amount of melanin and the amount of hemoglobin are calculated from the color information, and the hemoglobin of an arbitrary subject is calculated based on the regression equation of the amount of hemoglobin, the amount of melanin, the attenuation coefficient (μ eff ), and the skin appearance impression score. An aspect is provided that includes a calculation means for outputting an impression score of the skin appearance of the subject from the amount, the melanin amount, and the attenuation coefficient (μ eff ).

また、本発明は、
(a)皮膚表面に非接触に集光光と平行光を連続的に切り替え照射し、
(b)皮膚に照射した集光光の反射光を検出し、減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')を算出すると共に、
(c)皮膚に照射した平行光の反射光を検出し、色情報を計測する
皮膚の光学的性状の計測方法を提供する。
The present invention also provides:
(A) irradiating the skin surface in a non-contact manner by continuously switching and irradiating condensed light and parallel light;
(B) detecting the reflected light of the condensed light irradiated on the skin, calculating the attenuation coefficient (μ eff ), absorption coefficient (μ a ) or equivalent scattering coefficient (μ s ′);
(C) To provide a method for measuring the optical properties of skin by detecting reflected light of parallel light irradiated on the skin and measuring color information.

さらに本発明は、上述の計測方法において、前記色情報からメラニン量とヘモグロビン量を算出し、メラニン量、ヘモグロビン量、及び減衰係数(μeff)と、皮膚外観の印象スコアとの回帰式を求め、該回帰式に基づき、任意の被験者のヘモグロビン量、メラニン量及び減衰係数から該被験者の皮膚外観の印象のスコアを求める皮膚の評価方法を提供する。 Further, according to the present invention, in the measurement method described above, the amount of melanin and the amount of hemoglobin are calculated from the color information, and a regression equation of the melanin amount, the amount of hemoglobin, the attenuation coefficient (μ eff ), and the impression score of the skin appearance is obtained. Based on the regression equation, a skin evaluation method for obtaining a score of an impression of the skin appearance of the subject from the amount of hemoglobin, the amount of melanin and the attenuation coefficient of an arbitrary subject is provided.

本発明の計測装置によれば、皮膚表面に非接触に集光光と平行光を連続的に切り替え照射することができるので、集光光と平行光をほぼシャッタースピードの速さで瞬時に切り替えて皮膚に照射することができ、集光光の反射光と平行光の反射光とをほぼ同時に検出することが可能となる。したがって、集光光の反射光の検出により、皮膚の透明性の指標として算出される減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')と、平行光の反射光の色情報から算出されるメラニン量、ヘモグロビン量等とを、同時点での皮膚の計測値として得ることができ、これらの計測値と皮膚外観の印象スコアとに高い相関を持たせることができる。 According to the measuring device of the present invention, the condensed light and the parallel light can be continuously switched and irradiated on the skin surface in a non-contact manner, so that the condensed light and the parallel light are instantaneously switched at a substantially shutter speed. The reflected light of the condensed light and the reflected light of the parallel light can be detected almost simultaneously. Therefore, by detecting the reflected light of the collected light, the attenuation coefficient (μ eff ), absorption coefficient (μ a ) or equivalent scattering coefficient (μ s ′) calculated as an index of skin transparency, and reflection of parallel light Melanin amount, hemoglobin amount, etc. calculated from light color information can be obtained as skin measurement values at the same point, and these measurement values and skin appearance impression score can be highly correlated it can.

よって、本発明により得られた皮膚の透明性(減衰係数(μeff)等)と色情報(メラニン量等)から、皮膚外観の印象を、光学的な計測に基づく客観的な数値として得ることができる。また、予め、皮膚の透明性と色情報と、皮膚外観の印象スコアとの回帰式を求めておくことにより、任意の被験者について、透明性と色情報を計測することにより、皮膚外観の印象の客観的な評価値を得ることができる。 Therefore, from the skin transparency (attenuation coefficient (μ eff ), etc.) obtained by the present invention and color information (melanin amount, etc.), the impression of the appearance of the skin is obtained as an objective numerical value based on optical measurement. Can do. In addition, by obtaining a regression equation of skin transparency and color information and the impression score of skin appearance in advance, by measuring the transparency and color information for any subject, Objective evaluation values can be obtained.

さらに、皮膚の透明性の計測値(減衰係数(μeff)等)と色情報の計測値(メラニン量等)を重回帰分析することにより、皮膚外観の印象スコアに及ぼす透明性や色情報の寄与度を見積もったり、また、透明性が肌のテクスチャー(シミ、シワ、毛穴、血管の有無等)から受ける影響を評価することが可能となる。 Furthermore, by performing multiple regression analysis of skin transparency measurement values (such as attenuation coefficient (μ eff )) and color information measurement values (melanin content, etc.) It is possible to estimate the degree of contribution and to evaluate the influence of transparency on the skin texture (such as the presence or absence of spots, wrinkles, pores, blood vessels, etc.).

以下、図面を参照しつつ、本発明を詳細に説明する。なお、各図中、同一符号は同一又は同等の構成要素を表している。   Hereinafter, the present invention will be described in detail with reference to the drawings. In each figure, the same numerals indicate the same or equivalent components.

図1A及び図1Bは、本発明の一実施例の計測装置1Aであって、試料Sとする皮膚に集光光を照射している状態(図1A)と、平行光を照射している状態(図1B)の模式的構成図である。   1A and 1B show a measuring apparatus 1A according to an embodiment of the present invention, in which a skin as a sample S is irradiated with condensed light (FIG. 1A) and parallel light is irradiated. It is a typical block diagram of (FIG. 1B).

この装置1Aは、試料Sとする皮膚に、入射角0°で光を入射し、試料Sからの反射光を受光角(θ)45°で検出する装置であって、ハロゲン、メタルハライド等の白色光源2、白色光源2から導光した光を一端から出射し、点光源3として機能する光ファイバー(直径0.01〜1mm)4、点光源3から出射された光を集光する集光レンズ5、集光レンズ5の後段に設けられたコリメータレンズ7、集光レンズ5とコリメータレンズ7との間に設けられた絞り6、コリメータレンズ7により形成された平行光を試料Sに集光する集光レンズ8、受光角(θ)45°の向きに設置されたデジタルカメラ10を備えている。コリメータレンズ7と集光レンズ8との間には、必要に応じて、光量調節のための絞りを設けてもよい(図示せず)。ここで、集光レンズ8は、着脱自在となっている。したがって、図1Bに示すように集光レンズ8が光路から外された場合には、試料Sには、コリメータレンズ7から平行光が照射されることとなる。   This device 1A is a device that makes light incident on the skin as the sample S at an incident angle of 0 ° and detects the reflected light from the sample S at a light receiving angle (θ) of 45 °, and is white such as halogen or metal halide. Light source 2, light guided from white light source 2 is emitted from one end, optical fiber (diameter 0.01 to 1 mm) 4 functioning as point light source 3, and condenser lens 5 that condenses light emitted from point light source 3. , A collimator lens 7 provided at a subsequent stage of the condenser lens 5, a diaphragm 6 provided between the condenser lens 5 and the collimator lens 7, and a condenser that collects the parallel light formed by the collimator lens 7 on the sample S. An optical lens 8 and a digital camera 10 installed with a light receiving angle (θ) of 45 ° are provided. A diaphragm for adjusting the amount of light may be provided between the collimator lens 7 and the condenser lens 8 as needed (not shown). Here, the condensing lens 8 is detachable. Therefore, when the condenser lens 8 is removed from the optical path as shown in FIG. 1B, the sample S is irradiated with parallel light from the collimator lens 7.

また、この装置1Aのデジタルカメラ10には、該デジタルカメラ10が検出した画像から減衰係数(μeff)を算出する透明性計測手段と、デジタルカメラ10が検出した画像に基いて色情報を計測する測色手段が接続されている(図示せず)。 In addition, the digital camera 10 of the apparatus 1A measures color information based on transparency measuring means for calculating an attenuation coefficient (μ eff ) from an image detected by the digital camera 10 and an image detected by the digital camera 10. Color measuring means is connected (not shown).

減衰係数(μeff)を算出する透明性計測手段としては、例えば、デジタルカメラ10が検出した画像の動径方向の輝度分布を図2のように求め、必要に応じて、γ補正、暗電流補正等を行い、得られた輝度分布に対して、市販の科学的グラフ解析ソフトを使用し、次式 As the transparency measuring means for calculating the attenuation coefficient (μ eff ), for example, the luminance distribution in the radial direction of the image detected by the digital camera 10 is obtained as shown in FIG. 2, and if necessary, γ correction, dark current is obtained. Use a commercially available scientific graph analysis software for the brightness distribution obtained after correction, etc.

Figure 2006087748

(式中、r:動径距離(独立変数)
y:輝度(従属変数)
k:パラメータ )
で非線形曲線にフィッティングし、減衰係数(μeff)を算出する演算機能を有するパーソナルコンピュータを使用することができる。
Figure 2006087748

(Where r: radial distance (independent variable)
y: Luminance (dependent variable)
k: parameter)
Thus, it is possible to use a personal computer having a calculation function for fitting a nonlinear curve and calculating an attenuation coefficient (μ eff ).

この他、減衰係数(μeff)を算出する透明性計測手段としては、一対以上の送光用・受光用の光ファイバーの先端を対象物体(皮膚)に接触させ、送受光間隔を変えて測定するものをあげることができる。 In addition, as a transparency measuring means for calculating the attenuation coefficient (μ eff ), the tip of one or more optical fibers for light transmission / reception is brought into contact with the target object (skin), and measurement is performed by changing the light transmission / reception interval. I can give you something.

また、減衰係数(μeff)は、吸収係数μa と等価散乱係数μs'の関数であるから、透明性の指標としては、減衰係数(μeff)に代えて吸収係数μa や等価散乱係数μs' を用いてもよい。なお、これらには次の関係が成り立つ。






In addition, since the attenuation coefficient (μ eff ) is a function of the absorption coefficient μ a and the equivalent scattering coefficient μ s ′, as an index of transparency, the absorption coefficient μ a or equivalent scattering is used instead of the attenuation coefficient (μ eff ). The coefficient μ s ′ may be used. Note that the following relationship holds.






Figure 2006087748
一方、色情報を計測する測色手段としては、公知の測色計を使用することができるが、皮膚の画像信号からRGB各成分の強度を検出できるものが好ましく、また、この測色手段には、メラニン量又はヘモグロビン量、あるいは必要に応じてこれらの双方を算出する色素量算出手段を接続することが好ましい。色素量算出手段としては、例えば、画像信号のRGB各成分の強度から独立成分分析によりこれらの成分ベクトルを求め、メラニン量の分布画像やヘモグロビン量の分布画像を出力するものを使用することができる。このような解析処理と画像処理の詳細は、Vol.16,No.9/September 1999/J.Opt.Soc.Am.A2169に記載されており、パーソナルコンピュータに、市販の画像解析ソフト(例えば、Adobe Photoshop)を搭載することに実現することができる。
Figure 2006087748
On the other hand, as a colorimetric means for measuring color information, a known colorimeter can be used, but it is preferable to be able to detect the intensity of each RGB component from the skin image signal. Is preferably connected to a pigment amount calculating means for calculating the amount of melanin or the amount of hemoglobin, or if necessary, both of them. As the pigment amount calculation means, for example, a component that obtains these component vectors by independent component analysis from the intensity of each RGB component of the image signal and outputs a distribution image of the melanin amount or a distribution image of the hemoglobin amount can be used. . Details of such analysis processing and image processing are described in Vol. 16, No. 9 / September 1999 / J.Opt.Soc.Am.A2169, and commercially available image analysis software (for example, It can be realized by installing Adobe Photoshop.

この他、測色手段としては、光沢量の計測手段を設けてもよい。光沢量の計測手段は、入射光に対して鏡面方向の受光位置(たとえば、図1では入射角φ=0°で光を試料Sに入射させているが、この角度を入射角φ=−a°に変更した時のθ=a°方向)にカメラ等の計測器を配置し、更に偏光撮影技術を使用することにより構成できる。   In addition, a gloss amount measuring unit may be provided as the color measuring unit. The gloss amount measuring means has a light receiving position in a mirror surface direction with respect to incident light (for example, in FIG. 1, the light is incident on the sample S at an incident angle φ = 0 °. It can be configured by arranging a measuring instrument such as a camera in the direction of θ = a ° when the angle is changed to °, and using a polarization imaging technique.

なお、この装置1Aにおいて、点光源3から試料Sの照射面までの距離は、50〜5000mm、試料Sの照射面からデジタルカメラ10までの距離は60〜6000mm程度に組み立てればよい。   In this apparatus 1A, the distance from the point light source 3 to the irradiation surface of the sample S may be 50 to 5000 mm, and the distance from the irradiation surface of the sample S to the digital camera 10 may be assembled to about 60 to 6000 mm.

この装置1Aで試料Sの減衰係数(μeff)とメラニン量及びヘモグロビン量を計測する場合、まず、装置を設置している計測室を暗室とし、集光レンズ8を用いて試料Sに集光光を照射してその反射光を検出し(図1A)、引き続き、集光レンズ8を取り外して試料Sに平行光を照射してその反射光を検出する(図1B)。あるいは、まず、試料Sに平行光を照射してその反射光を検出し(図1B)、次いで集光光を照射してその反射光を検出する(図1A)。 When measuring the attenuation coefficient (μ eff ), the amount of melanin, and the amount of hemoglobin of the sample S with this apparatus 1A, first, the measurement chamber in which the apparatus is installed is a dark room, and the light is condensed on the sample S using the condenser lens 8. The reflected light is detected by irradiating light (FIG. 1A). Subsequently, the condenser lens 8 is removed and the sample S is irradiated with parallel light to detect the reflected light (FIG. 1B). Alternatively, first, the sample S is irradiated with parallel light to detect the reflected light (FIG. 1B), and then the condensed light is irradiated to detect the reflected light (FIG. 1A).

そして、集光光の反射光の検出信号から皮膚の透明性のパラメータとして、減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')を算出し、また、平行光の反射光の検出信号から色情報を求め、さらにメラニン量及びヘモグロビン量を算出する。これにより、瞬時に、より具体的には1/100秒〜20秒というシャッタースピードの速さで検出光を切り替え、皮膚の透明性のパラメータである減衰係数(μeff)等と、色情報に対応するメラニン量やヘモグロビン量とを得ることができる。よって、透明性の計測時と色情報の計測時で、これらに影響を及ぼす被験者の心理的状態をそろえることができ、これらと皮膚の印象スコアとに高い相関を持たせることができる。 Then, an attenuation coefficient (μ eff ), an absorption coefficient (μ a ), or an equivalent scattering coefficient (μ s ′) is calculated as a skin transparency parameter from the detection signal of the reflected light of the collected light, and the parallel light Color information is obtained from the detection signal of the reflected light, and the amount of melanin and the amount of hemoglobin are further calculated. As a result, the detection light is switched instantaneously, more specifically, at a shutter speed of 1/100 second to 20 seconds, and the attenuation coefficient (μ eff ), which is a parameter of skin transparency, is displayed in the color information. The corresponding melanin amount and hemoglobin amount can be obtained. Therefore, it is possible to align the psychological state of the subject that affects these during the measurement of transparency and the measurement of color information, and to have a high correlation between these and the impression score of the skin.

即ち、図3A、図3Bに示すように、光ファイバー11から皮膚S1 、S2 に光を入射させた場合に、一般に、外観の印象がきれいな皮膚S1 は、外観の印象が劣る皮膚S2 に対して光の染み出す範囲(光侵達領域)Aが広い。   That is, as shown in FIGS. 3A and 3B, when light is incident on the skins S1 and S2 from the optical fiber 11, in general, the skin S1 having a clean appearance looks light against the skin S2 having a poor appearance. Extrusion range (light penetration area) A is wide.

したがって、皮膚外観の印象を、最低を1、最高を7として7段階にスコア付けした場合に、光の侵達長(減衰係数(μeff)の逆数)と印象スコアとはある程度の相関性を有するが、侵達長、メラニン量及びヘモグロビン量と、印象スコアとの重回帰分析をすることにより得た相関性はより向上したものとなり、この場合に、侵達長、メラニン量及びヘモグロビン量を本発明の方法によりほぼ同時計測したものとすると、さらにこれらと印象スコアとの相関性を高めることができる。 Therefore, when the skin appearance impression is scored in 7 stages, with the lowest being 1 and the highest being 7, there is a certain degree of correlation between the light penetration length (the reciprocal of the attenuation coefficient (μ eff )) and the impression score. However, the correlation obtained by performing multiple regression analysis of the penetration length, melanin amount and hemoglobin amount and the impression score is improved, and in this case, the penetration length, melanin amount and hemoglobin amount are reduced. If the measurement is performed almost simultaneously by the method of the present invention, the correlation between these and the impression score can be further increased.

よって、予め、多数人の所定部位の皮膚について、本発明の方法により、メラニン量、ヘモグロビン量及び減衰係数(μeff)を同時計測すると共に、その皮膚外観の印象スコアを専門パネルから得、メラニン量、ヘモグロビン量及び減衰係数(μeff)と印象スコアとを重回帰分析して回帰式を求め、一方、任意の被験者について同様にメラニン量、ヘモグロビン量及び減衰係数(μeff)を求め、前記回帰式に基づいて皮膚の印象スコアを算出すると、その印象スコアを、当該被験者の皮膚外観の印象の客観的評価値として使用することができる。 Therefore, with respect to the skin of a predetermined site of a large number of people, the melanin amount, hemoglobin amount, and attenuation coefficient (μ eff ) are simultaneously measured by the method of the present invention, and an impression score of the skin appearance is obtained from a specialized panel. The amount of hemoglobin, the amount of hemoglobin and attenuation coefficient (μ eff ) and the impression score are subjected to multiple regression analysis to obtain a regression equation, while the melanin amount, hemoglobin amount and attenuation coefficient (μ eff ) are similarly determined for any subject, When the skin impression score is calculated based on the regression equation, the impression score can be used as an objective evaluation value of the skin appearance impression of the subject.

以上、図1A及び図1Bに示した装置に基づいて本発明を説明したが、本発明は種々の態様をとることができる。   Although the present invention has been described above based on the apparatus shown in FIGS. 1A and 1B, the present invention can take various forms.

例えば、図4A及び図4Bに示す装置1Bのように、点光源3とコリメータレンズ7の間で集光レンズ5を省略してもよい。この場合、コリメータレンズ7としては、アクロマートレンズを使用することが好ましい。また、図4Aでコリメータレンズ7と集光レンズ8との間に絞りを設けてもよい(図示せず)。   For example, the condensing lens 5 may be omitted between the point light source 3 and the collimator lens 7 as in the apparatus 1B shown in FIGS. 4A and 4B. In this case, it is preferable to use an achromatic lens as the collimator lens 7. 4A, a stop may be provided between the collimator lens 7 and the condenser lens 8 (not shown).

また、着脱自在に設けられる集光レンズ8と試料Sとの間にペリクルハーフミラー12を試料Sに対して45°傾けて設け、垂直方向の反射光を検出(受光角0°)するようにしてもよい。ハーフミラーを使わない0°入射45°受光は構造が簡便であるが、ハーフミラーを使うことにより内部散乱光の広がりが同心円状になる状態で撮影できるため、光量の積分等が容易である。   Further, a pellicle half mirror 12 is provided at an angle of 45 ° with respect to the sample S between the condensing lens 8 and the sample S which are detachably provided, and the reflected light in the vertical direction is detected (light receiving angle 0 °). May be. Light reception at 0 ° incidence and 45 ° without using a half mirror has a simple structure. However, by using a half mirror, it is possible to photograph in a state where the spread of the internally scattered light is concentric, so that the integration of the amount of light is easy.

さらに、図5A、図5Bに示す装置1Cのように、図4A及び図4Bに示した装置1Bにおいて、点光源3以降のレンズ系を筐体13中に収容してもよい。これにより、計測時に装置を暗室で使用することが不要となる。筐体13の大きさとしては、底面の縦及び横の長さをそれぞれ30mm〜500mm程度、高さを20〜200mm程度とすることができる。   Further, like the device 1C shown in FIGS. 5A and 5B, in the device 1B shown in FIGS. 4A and 4B, the lens system after the point light source 3 may be accommodated in the housing 13. This eliminates the need to use the device in a dark room during measurement. As the size of the housing 13, the vertical and horizontal lengths of the bottom surface can be about 30 mm to 500 mm, respectively, and the height can be about 20 to 200 mm.

また、筐体13にはディフューザー14を設けてもよい。なお、符号15はミラーである。   The housing 13 may be provided with a diffuser 14. Reference numeral 15 denotes a mirror.

実施例1
(1)印象スコア
15〜47歳の女性51名を被験者とし、頬部の20mm四方を測定部位として、約1m離れた位置からの専門パネル5名の目視により、各測定部位の外観印象を次の7段階に評価し、5名の評価値の平均をとった。
7:透明感に優れ、色白でととてもきれい
6:きれい
5:ややきれい
4:どちらでもない
3:ややきれいでない
2:きれいでない
1:透明感が劣り、浅黒く、とてもきれいでない
Example 1
(1) Impression score The appearance impression of each measurement site is as follows by visual observation of 5 professional panels from a position about 1 m away, with 51 females aged 15 to 47 years old as subjects and 20 mm square of the cheek as a measurement site. The average of the evaluation values of five people was taken.
7: Excellent transparency and fairness 6: Clean 5: Slightly clean 4: Neither 4: Slightly clean 2: Not clean 1: Inferior in transparency, dark, not very clean

(2)減衰係数μeffの算出
暗室内で、図4A、図4Bの装置を用いて、メタルハライドを光源とする白色光を点状(直径約100μm)に前記測定部位に集光させ、その反射光画像をデジタルカメラで撮った(露光時間5秒)。
(2) Calculation of attenuation coefficient μ eff Using the apparatus shown in FIGS. 4A and 4B, white light having a metal halide as a light source is focused on the measurement site in a dotted manner (diameter: about 100 μm) and reflected. A light image was taken with a digital camera (exposure time 5 seconds).

反射光画像のスポットの中心から動径方向への輝度分布を求め、γ補正と暗電流補正を行い、動径距離が1.5〜10mmの範囲における輝度分布(減衰曲線)に対して、科学的グラフ・解析ソフトウェア(ORIGIN、OriginLab社)を用いて次式で非線形曲線フィットし、減衰係数μeffを求めた。 The luminance distribution in the radial direction from the center of the spot of the reflected light image is obtained, γ correction and dark current correction are performed, and the luminance distribution (attenuation curve) in the range where the radial distance is 1.5 to 10 mm is scientific. A nonlinear curve was fit by the following equation using a statistical graph / analysis software (ORIGIN, OriginLab) to determine the attenuation coefficient μ eff .

Figure 2006087748

(式中、r:動径距離(独立変数)
y:輝度(従属変数)
k:パラメータ )
Figure 2006087748

(Where r: radial distance (independent variable)
y: Luminance (dependent variable)
k: parameter)

(3)メラニン量、ヘモグロビン量の算出
(2)の反射光画像を撮った後、集光レンズ8を外して前記測定部位の反射光画像を撮り、そのRGB各成分の強度を検出し、独立成分分析を行うことによりメラニン量とヘモグロビン量を算出した。
(3) Calculation of the amount of melanin and the amount of hemoglobin After taking the reflected light image of (2), remove the condenser lens 8, take the reflected light image of the measurement site, detect the intensity of each RGB component, and independently The amount of melanin and the amount of hemoglobin were calculated by component analysis.

(4)減衰係数μeff、メラニン量及びヘモグロビン量と印象スコアとの重相関
(4-1)印象スコアと減衰係数μeffとの相関係数を求めたところ、0.52であった。この場合の相関図を図6に示す。
(4) Multiple correlations between the attenuation coefficient μ eff , the amount of melanin and hemoglobin, and the impression score
(4-1) The correlation coefficient between the impression score and the attenuation coefficient μ eff was found to be 0.52. A correlation diagram in this case is shown in FIG.

(4-2)減衰係数μeffを求める反射光画像と、メラニン量及びヘモグロビン量を求める反射光画像の検出間隔を10分として、減衰係数μeff、メラニン量及びヘモグロビン量を算出し、これらと印象スコアとの重相関をとった。その結果、相関係数0.62を得た。この場合の相関図を図7に示す。 (4-2) and the reflected light image to obtain the attenuation coefficient mu eff, as 10 min detection interval of the reflected light image to obtain the amount of melanin and hemoglobin amount, attenuation coefficient mu eff, to calculate the amount of melanin and hemoglobin amount, and these A multiple correlation with the impression score was taken. As a result, a correlation coefficient of 0.62 was obtained. A correlation diagram in this case is shown in FIG.

(4-3)減衰係数μeffを求める反射光画像と、メラニン量及びヘモグロビン量を求める反射光画像とをほぼ同時(双方の画像の撮影間隔10秒)として、減衰係数μeff、メラニン量及びヘモグロビン量を算出し、これらと印象スコアとの重相関をとった。その結果、相関係数0.71を得た。この場合の相関図を図8に示す。 (4-3) The reflected light image for obtaining the attenuation coefficient μ eff and the reflected light image for obtaining the amount of melanin and hemoglobin are set almost simultaneously (10 seconds between both images), and the attenuation coefficient μ eff , the amount of melanin and The amount of hemoglobin was calculated, and a multiple correlation was obtained between these and the impression score. As a result, a correlation coefficient of 0.71 was obtained. A correlation diagram in this case is shown in FIG.

(4-1)〜(4-3)の結果から、減衰係数μeffを求める反射光画像と、メラニン量及びヘモグロビン量を求める反射光画像とをほぼ同時に撮り、減衰係数μeff、メラニン量及びヘモグロビン量を算出することにより、皮膚の外的環境や心理的環境の変化が皮膚血流を変化させてこれらに及ぼす影響を最小限に抑制することができる。よって、減衰係数μeff、メラニン量及びヘモグロビン量と、印象スコアとの相関性を高められることがわかる。 From the results of (4-1) to (4-3), the reflected light image for determining the attenuation coefficient μ eff and the reflected light image for determining the melanin amount and the hemoglobin amount are taken almost simultaneously, and the attenuation coefficient μ eff , the melanin amount and By calculating the amount of hemoglobin, it is possible to minimize the influence of changes in the external environment and psychological environment of the skin on the skin blood flow and affecting them. Therefore, it can be seen that the correlation between the attenuation coefficient μ eff , the melanin amount and the hemoglobin amount, and the impression score can be enhanced.

本発明によれば、皮膚外観の印象を、皮膚の透明性や色情報という光学的な計測値に基づいて表すことができるので、本発明は、種々の美容方法や化粧料の評価に有用となる。   According to the present invention, the impression of the appearance of the skin can be expressed based on optical measurement values such as skin transparency and color information. Therefore, the present invention is useful for evaluating various beauty methods and cosmetics. Become.

試料に集光光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example in the state which irradiates the condensed light to the sample. 試料に平行光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example of the state which irradiates a sample with parallel light. 画像の輝度と動径距離との関係図である。FIG. 4 is a relationship diagram between image brightness and radial distance. 外観印象がきれいな皮膚における光の染み出し状態の説明図である。It is explanatory drawing of the oozing-out state of the light in skin with a beautiful external appearance impression. 外観印象が劣る皮膚における光の染み出し状態の説明図である。It is explanatory drawing of the oozing-out state of light in the skin where an external appearance impression is inferior. 試料に集光光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example in the state which irradiates the condensed light to the sample. 試料に平行光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example of the state which irradiates a sample with parallel light. 試料に集光光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example in the state which irradiates the condensed light to the sample. 試料に平行光を照射している状態の実施例の装置の模式的構成図である。It is a typical block diagram of the apparatus of the Example of the state which irradiates a sample with parallel light. 減衰係数μeffと印象スコアとの相関図である。FIG. 4 is a correlation diagram between an attenuation coefficient μ eff and an impression score. 減衰係数μeffとメラニン量及びヘモグロビン量との計測間隔をあけた場合の減衰係数μeff、メラニン量及びヘモグロビン量、と印象スコアとの相関図である。Attenuation coefficient mu eff when spaced measurement interval between the attenuation coefficient mu eff and the amount of melanin and hemoglobin, a correlation diagram of the amount of melanin and hemoglobin amount, and the impression score. ほぼ同時に計測した減衰係数μeff、メラニン量及びヘモグロビン量、と印象スコアとの相関図である。FIG. 6 is a correlation diagram of attenuation coefficient μ eff , melanin amount and hemoglobin amount, and impression score measured almost simultaneously.

符号の説明Explanation of symbols

1A、1B、1C 皮膚の光学的性状の計測装置
2 白色光源
3 点光源
4 光ファイバー
5 集光レンズ
6 絞り
7 コリメータレンズ
8 集光レンズ
10 デジタルカメラ
11 光ファイバー
12 ペリクルハーフミラー
13 筐体
14 ディフューザー
15 ミラー
S、S1 、S2 試料又は皮膚
1A, 1B, 1C Measuring device for optical properties of skin 2 White light source 3 Point light source 4 Optical fiber 5 Condensing lens 6 Aperture 7 Collimator lens 8 Condensing lens 10 Digital camera 11 Optical fiber 12 Pellicle half mirror 13 Housing 14 Diffuser 15 Mirror S, S1, S2 sample or skin

Claims (6)

(A)、(B)及び(C):
(A)皮膚表面に非接触に集光光と平行光を連続的に切り替え照射することのできる照射手段、
(B)皮膚に照射した集光光の反射光を検出し、減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')を算出する透明性計測手段、
(C)皮膚に照射した平行光の反射光を検出し、色情報を計測する測色手段
を備えた皮膚の光学的性状の計測装置。
(A), (B) and (C):
(A) Irradiation means capable of continuously switching and irradiating condensed light and parallel light in a non-contact manner on the skin surface;
(B) a transparency measuring means for detecting reflected light of the condensed light irradiated on the skin and calculating an attenuation coefficient (μ eff ), an absorption coefficient (μ a ), or an equivalent scattering coefficient (μ s ′);
(C) An apparatus for measuring the optical properties of skin, comprising colorimetric means for detecting reflected light of parallel light irradiated on the skin and measuring color information.
さらに、前記色情報からメラニン量又はヘモグロビン量を算出する色素量算出手段を有する請求項1記載の計測装置。   The measuring apparatus according to claim 1, further comprising a pigment amount calculating unit that calculates a melanin amount or a hemoglobin amount from the color information. メラニン量、ヘモグロビン量及び減衰係数(μeff)と皮膚外観の印象スコアとの回帰式に基づき、任意の被験者のメラニン量、ヘモグロビン量及び減衰係数(μeff)から該被験者の皮膚外観の印象スコアを出力する演算手段を備えた請求項1記載の計測装置。 Amount of melanin, hemoglobin content and based on the regression equation of the impression score attenuation coefficient (mu eff) and skin appearance, melanin amount of any subject, the quantity of hemoglobin and the attenuation coefficient (mu eff) of the subject impression score skin appearance The measuring device according to claim 1, further comprising a calculation means for outputting (a)皮膚表面に非接触に集光光と平行光を連続的に切り替え照射し、
(b)皮膚に照射した集光光の反射光を検出し、減衰係数(μeff)、吸収係数(μa)又は等価散乱係数(μs')を算出すると共に、
(c)皮膚に照射した平行光の反射光を検出し、色情報を計測する
皮膚の光学的性状の計測方法。
(A) irradiating the skin surface in a non-contact manner by continuously switching and irradiating condensed light and parallel light;
(B) detecting the reflected light of the condensed light irradiated on the skin, calculating the attenuation coefficient (μ eff ), absorption coefficient (μ a ) or equivalent scattering coefficient (μ s ′);
(C) A method for measuring the optical properties of the skin by detecting reflected light of parallel light irradiated on the skin and measuring color information.
さらに、前記色情報からメラニン量又はヘモグロビン量を算出する請求項4記載の計測方法。   Furthermore, the measuring method of Claim 4 which calculates the amount of melanin or the amount of hemoglobin from the said color information. 請求項5記載の方法により算出したメラニン量、ヘモグロビン量及び減衰係数(μeff)と、皮膚外観の印象スコアとの回帰式を求め、該回帰式に基づき、任意の被験者のメラニン量、ヘモグロビン量及び減衰係数(μeff)から該被験者の皮膚外観の印象スコアを求める皮膚の評価方法。
A regression equation of the melanin amount, hemoglobin amount and attenuation coefficient (μ eff ) calculated by the method according to claim 5 and an impression score of skin appearance is obtained, and based on the regression equation, the melanin amount and hemoglobin amount of any subject And a skin evaluation method for obtaining an impression score of the skin appearance of the subject from the attenuation coefficient (μ eff ).
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WO2011105731A2 (en) * 2010-02-26 2011-09-01 (주)아모레퍼시픽 System and method for measuring skin color
WO2016151992A1 (en) * 2015-03-26 2016-09-29 パナソニックIpマネジメント株式会社 Skin diagnosis device

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JPH0835928A (en) * 1994-07-20 1996-02-06 Unitec Res Kk Imaging apparatus
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WO2011105731A2 (en) * 2010-02-26 2011-09-01 (주)아모레퍼시픽 System and method for measuring skin color
WO2011105731A3 (en) * 2010-02-26 2012-01-12 (주)아모레퍼시픽 System and method for measuring skin color
WO2016151992A1 (en) * 2015-03-26 2016-09-29 パナソニックIpマネジメント株式会社 Skin diagnosis device
JP2016182235A (en) * 2015-03-26 2016-10-20 パナソニックIpマネジメント株式会社 Skin diagnosis device

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