ITMI20042007A1 - "modulatori del ricettore gpr17 e loro impieghi terapeutici" - Google Patents
"modulatori del ricettore gpr17 e loro impieghi terapeutici"Info
- Publication number
- ITMI20042007A1 ITMI20042007A1 IT002007A ITMI20042007A ITMI20042007A1 IT MI20042007 A1 ITMI20042007 A1 IT MI20042007A1 IT 002007 A IT002007 A IT 002007A IT MI20042007 A ITMI20042007 A IT MI20042007A IT MI20042007 A1 ITMI20042007 A1 IT MI20042007A1
- Authority
- IT
- Italy
- Prior art keywords
- gpr17
- recipe
- modulators
- therapeutic uses
- therapeutic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Physics & Mathematics (AREA)
- Cardiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Neurology (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002007A ITMI20042007A1 (it) | 2004-10-21 | 2004-10-21 | "modulatori del ricettore gpr17 e loro impieghi terapeutici" |
EP05795031A EP1807701A2 (en) | 2004-10-21 | 2005-10-17 | Gpr17 modulators, method of screening and uses thereof |
JP2007537181A JP2008516617A (ja) | 2004-10-21 | 2005-10-17 | Gpr17調節因子、そのスクリーニング方法、およびその使用 |
PCT/EP2005/011157 WO2006045476A2 (en) | 2004-10-21 | 2005-10-17 | Gpr17 modulators, method of screening and uses thereof |
US11/665,835 US8158593B2 (en) | 2004-10-21 | 2005-10-17 | GPR17 modulators, method of screening and uses thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002007A ITMI20042007A1 (it) | 2004-10-21 | 2004-10-21 | "modulatori del ricettore gpr17 e loro impieghi terapeutici" |
Publications (1)
Publication Number | Publication Date |
---|---|
ITMI20042007A1 true ITMI20042007A1 (it) | 2005-01-21 |
Family
ID=35598398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT002007A ITMI20042007A1 (it) | 2004-10-21 | 2004-10-21 | "modulatori del ricettore gpr17 e loro impieghi terapeutici" |
Country Status (5)
Country | Link |
---|---|
US (1) | US8158593B2 (it) |
EP (1) | EP1807701A2 (it) |
JP (1) | JP2008516617A (it) |
IT (1) | ITMI20042007A1 (it) |
WO (1) | WO2006045476A2 (it) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1402549B1 (it) | 2010-11-03 | 2013-09-13 | Univ Pisa | Composti e composizioni che modulano gpr17 e loro usi terapeutici e diagnostici |
EP2727030A4 (en) * | 2011-06-29 | 2015-05-27 | Univ Johns Hopkins | SYSTEM FOR A THREE-DIMENSIONAL INTERFACE AND DATABASE |
EP2567698B1 (en) | 2011-09-07 | 2014-02-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | GPR 17 agonists and screening assay |
KR20150008468A (ko) | 2012-05-09 | 2015-01-22 | 폰다지오네 이탈리아나 스클레로시 멀티플라 - 에프아이에스엠 온러스 | Gpr17 수용체 조절제 |
DE102016213926B4 (de) * | 2016-07-28 | 2018-10-31 | Siemens Healthcare Gmbh | Verfahren zur Bestimmung eines Diffusionstensors mittels eines Magnetresonanztomographen und Vorrichtung |
TWI754702B (zh) | 2016-12-28 | 2022-02-11 | 德商Ucb製藥有限公司 | (氮雜)吲哚-和苯並呋喃-3-磺醯胺類 |
KR20210018267A (ko) | 2018-05-07 | 2021-02-17 | 알닐람 파마슈티칼스 인코포레이티드 | 간외 전달 |
SI4074703T1 (sl) * | 2018-06-19 | 2024-03-29 | Ucb Pharma Gmbh | Piridinil-(aza)indolsulfonamidi |
EP3584244A1 (en) | 2018-06-20 | 2019-12-25 | UCB Pharma GmbH | Substituted alkoxypyridinyl indolsulfonamides |
WO2020254289A1 (en) | 2019-06-17 | 2020-12-24 | Ucb Pharma Gmbh | N-(phenyl)-indole-3-sulfonamide derivatives and related compounds as gpr17 modulators for treating cns disorders such as multiple sclerosis |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5759804A (en) * | 1992-11-17 | 1998-06-02 | Icos Corporation | Isolated nucleic acid encoding seven transmembrane receptors |
WO1996039438A1 (en) * | 1995-06-06 | 1996-12-12 | Human Genome Sciences, Inc. | G-protein receptor hibeb69 |
GB0003902D0 (en) * | 2000-02-18 | 2000-04-05 | Glaxo Group Ltd | Assay |
AU2001244205A1 (en) * | 2000-03-14 | 2001-09-24 | Bayer Aktiengesellschaft | Regulation of human p2y-like gpcr protein |
WO2005040829A2 (en) * | 2003-10-21 | 2005-05-06 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 17 (gpr17) |
-
2004
- 2004-10-21 IT IT002007A patent/ITMI20042007A1/it unknown
-
2005
- 2005-10-17 WO PCT/EP2005/011157 patent/WO2006045476A2/en active Application Filing
- 2005-10-17 US US11/665,835 patent/US8158593B2/en not_active Expired - Fee Related
- 2005-10-17 EP EP05795031A patent/EP1807701A2/en not_active Withdrawn
- 2005-10-17 JP JP2007537181A patent/JP2008516617A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2008516617A (ja) | 2008-05-22 |
WO2006045476A3 (en) | 2006-07-20 |
WO2006045476A2 (en) | 2006-05-04 |
US8158593B2 (en) | 2012-04-17 |
EP1807701A2 (en) | 2007-07-18 |
US20090156521A1 (en) | 2009-06-18 |
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