[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IT8322572A0 - Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche. - Google Patents

Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.

Info

Publication number
IT8322572A0
IT8322572A0 IT8322572A IT2257283A IT8322572A0 IT 8322572 A0 IT8322572 A0 IT 8322572A0 IT 8322572 A IT8322572 A IT 8322572A IT 2257283 A IT2257283 A IT 2257283A IT 8322572 A0 IT8322572 A0 IT 8322572A0
Authority
IT
Italy
Prior art keywords
derivatives
procedure
preparation
pharmaceutical compositions
bile acids
Prior art date
Application number
IT8322572A
Other languages
English (en)
Other versions
IT1212835B (it
Inventor
Virginio Castagnola
Giuliano E Frigerio
Roberto Pellicciari
Aldo Roda
Original Assignee
Lehner Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lehner Ag filed Critical Lehner Ag
Priority to IT8322572A priority Critical patent/IT1212835B/it
Publication of IT8322572A0 publication Critical patent/IT8322572A0/it
Priority to AT84109811T priority patent/ATE50583T1/de
Priority to ES535267A priority patent/ES535267A0/es
Priority to DE8484109811T priority patent/DE3481419D1/de
Priority to JP59171376A priority patent/JPH0144197B2/ja
Priority to EP84109811A priority patent/EP0135782B1/en
Priority to US07/415,614 priority patent/US4981983A/en
Application granted granted Critical
Publication of IT1212835B publication Critical patent/IT1212835B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8322572A 1983-08-18 1983-08-18 Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche. IT1212835B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8322572A IT1212835B (it) 1983-08-18 1983-08-18 Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
AT84109811T ATE50583T1 (de) 1983-08-18 1984-08-17 Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.
ES535267A ES535267A0 (es) 1983-08-18 1984-08-17 Un procedimiento para la preparacion de compuestos
DE8484109811T DE3481419D1 (de) 1983-08-18 1984-08-17 Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.
JP59171376A JPH0144197B2 (en) 1983-08-18 1984-08-17 Gallic acid derivatives, manufacture and pharmaceutical composition
EP84109811A EP0135782B1 (en) 1983-08-18 1984-08-17 New derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
US07/415,614 US4981983A (en) 1983-08-18 1989-10-02 Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8322572A IT1212835B (it) 1983-08-18 1983-08-18 Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
IT8322572A0 true IT8322572A0 (it) 1983-08-18
IT1212835B IT1212835B (it) 1989-11-30

Family

ID=11197972

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8322572A IT1212835B (it) 1983-08-18 1983-08-18 Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.

Country Status (7)

Country Link
US (1) US4981983A (it)
EP (1) EP0135782B1 (it)
JP (1) JPH0144197B2 (it)
AT (1) ATE50583T1 (it)
DE (1) DE3481419D1 (it)
ES (1) ES535267A0 (it)
IT (1) IT1212835B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196377B (it) * 1984-12-21 1988-11-16 Lehner Ag Derivati di acidi biliari,procedimento per la loro preparazione e relative composizioni farmaceutiche
HU206367B (en) * 1988-04-30 1992-10-28 Sandoz Ag Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts
IT1255449B (it) * 1992-06-30 1995-10-31 Fabio Berlati Uso di nor- e omo-derivati di acidi biliari come promotori di assorbimento di farmaci.
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
US6767904B2 (en) 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
US6350738B1 (en) 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
USRE48286E1 (en) 2001-03-12 2020-10-27 Intercept Pharmaceuticals, Inc. Steroids as agonists for FXR
US10987362B2 (en) 2004-03-12 2021-04-27 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using FXR ligands
DK2712617T3 (en) 2004-03-12 2017-02-13 Intercept Pharmaceuticals Inc Treatment of fibrosis with Fxr ligands.
ITMI20050912A1 (it) 2005-05-19 2006-11-20 Erregierre Spa Processo di preparazione di acidi 3-a-ya(b)-diidrossi-6-a(b)-alchil-5b-colanici
JP5292310B2 (ja) 2007-01-19 2013-09-18 インターセプト ファーマシューティカルズ, インコーポレイテッド Tgr5調節剤としての23−置換胆汁酸およびその使用方法
EP1947108A1 (en) * 2007-01-19 2008-07-23 Intercept Pharmaceuticals, Inc. TGR5 modulators and methods of use thereof
CA2732323C (en) 2008-07-30 2017-06-27 Intercept Pharmaceuticals, Inc. Tgr5 modulators and methods of use thereof
PT2376519E (pt) 2008-11-19 2014-02-20 Intercept Pharmaceuticals Inc Moduladores de tgr5 e métodos da sua utilização
WO2013192097A1 (en) 2012-06-19 2013-12-27 Intercept Pharmaceuticals, Inc. Preparation, uses and solid forms of obeticholic acid
US9982008B2 (en) 2012-06-19 2018-05-29 Intercept Pharmaceuticals, Inc. Preparation and uses of obeticholic acid
US20140206657A1 (en) * 2013-01-18 2014-07-24 City Of Hope Bile acid analog tgr5 agonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997664A (en) * 1971-02-09 1976-12-14 Sandoz, Inc. Substituted carbinol derivatives
US4104285A (en) * 1977-04-22 1978-08-01 Hoffmann-La Roche Inc. Taurine and glycine derivatives
US4117121A (en) * 1977-04-22 1978-09-26 Hoffmann-La Roche Inc. Method of increasing bile flow and decreasing lipid levels
NL8003999A (nl) * 1980-07-11 1982-02-01 Akzo Nv Nieuwe 8 alfa-oestra-1,3,5(10)-trieen-derivaten en de bereiding daarvan.
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
DE3260539D1 (en) * 1981-05-29 1984-09-13 Glaxo Group Ltd 11-alpha-amino-androstanes
DE3260462D1 (en) * 1981-05-29 1984-08-30 Glaxo Group Ltd 11-alpha-amino-androstanes
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
DE3366932D1 (en) * 1982-07-29 1986-11-20 Lehner Ag New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
FR2610933B1 (fr) * 1987-02-18 1989-06-09 Roussel Uclaf Nouveaux 19-nor steroides substitues en position 7, leur preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
ES8506047A1 (es) 1985-06-16
IT1212835B (it) 1989-11-30
US4981983A (en) 1991-01-01
JPH0144197B2 (en) 1989-09-26
ES535267A0 (es) 1985-06-16
DE3481419D1 (de) 1990-04-05
ATE50583T1 (de) 1990-03-15
JPS6075495A (ja) 1985-04-27
EP0135782B1 (en) 1990-02-28
EP0135782A3 (en) 1985-12-11
EP0135782A2 (en) 1985-04-03

Similar Documents

Publication Publication Date Title
IT1206112B (it) Nuovi derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT8920170A0 (it) Derivati fluorurati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
IT8322572A0 (it) Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT8722343A0 (it) Derivati di acidi biliari loro preparazione e composizioni farmaceutiche che li contengono.
IT8620846A0 (it) Derivati di acido valproico e di acido (e)-2-valproenoico, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT8920169A0 (it) Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
IT8424187A0 (it) Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT7827493A0 (it) Derivati di acidi amidinosolfonici, processo per la loro preparazione e composizioni farmaceutiche che contengono questi derivati.
IT1147846B (it) Derivati di acidi fenil alifatico carbossilici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1195267B (it) Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT8667976A0 (it) Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
IT1193590B (it) Derivati amino-alchil-solfonici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT8320278A0 (it) Derivati delle rifamicine eprocedimento per la loro preparazione.
IT8319219A0 (it) Derivati di arilossipropanolamina, procedimento per la loro preparazione composizioni farmaceutiche cheli contengono e loro impiego terapeutico
IT8023601A0 (it) Derivati ammidici dell'acido p-isobutilfenilpropionico, procedimento per la loro preparazione e relative composizioni farmaceutici.
IT8321909A0 (it) Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT8224576A0 (it) Derivati di acidi aminopiridincarbossilici,loro metodi di sintesi e composizioni farmaceutiche che licontengono
IT8222632A0 (it) Derivati di acidi biliari,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT8020764A0 (it) Esteri e derivati chinucleidinici di acidi fenossicarbossilici, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT8224755A0 (it) Nuovi derivati di acidi fenilacetici, loro preparazione e composizioni che li contengono.
IT8922275A0 (it) Nuovi derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT8221235A0 (it) Derivati di acidi biliari,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT8221236A0 (it) Derivati di acidi biliari,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT8621135A0 (it) Derivati dell'acito cef-3-em-4-carbossilico, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT1172237B (it) Derivati di amminoacidi particolarmente utili come medicammenti e procedimento per la loro preparazione

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960731