IT1266571B1 - Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari - Google Patents
Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolariInfo
- Publication number
- IT1266571B1 IT1266571B1 IT93MI001723A ITMI931723A IT1266571B1 IT 1266571 B1 IT1266571 B1 IT 1266571B1 IT 93MI001723 A IT93MI001723 A IT 93MI001723A IT MI931723 A ITMI931723 A IT MI931723A IT 1266571 B1 IT1266571 B1 IT 1266571B1
- Authority
- IT
- Italy
- Prior art keywords
- useful
- treatment
- cardiovascular diseases
- propanamide
- mercapto
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001723A IT1266571B1 (it) | 1993-07-30 | 1993-07-30 | Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari |
DE69402004T DE69402004T2 (de) | 1993-07-30 | 1994-07-25 | Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder Erkrankungen |
EP94111584A EP0636621B1 (en) | 1993-07-30 | 1994-07-25 | Beta-mercapto-propanamide derivatives useful in the treatment of cardiovascular diseases |
AT94111584T ATE150019T1 (de) | 1993-07-30 | 1994-07-25 | Beta-mercapto-propanamidderivate verwendbar zur behandlung kardiovaskularer krankheiten oder erkrankungen |
US08/281,105 US5506259A (en) | 1993-07-30 | 1994-07-27 | β-mercapto-propanamide derivatives useful in the treatment of cardiovascular diseases |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001723A IT1266571B1 (it) | 1993-07-30 | 1993-07-30 | Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931723A0 ITMI931723A0 (it) | 1993-07-30 |
ITMI931723A1 ITMI931723A1 (it) | 1995-01-30 |
IT1266571B1 true IT1266571B1 (it) | 1997-01-09 |
Family
ID=11366739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT93MI001723A IT1266571B1 (it) | 1993-07-30 | 1993-07-30 | Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari |
Country Status (5)
Country | Link |
---|---|
US (1) | US5506259A (it) |
EP (1) | EP0636621B1 (it) |
AT (1) | ATE150019T1 (it) |
DE (1) | DE69402004T2 (it) |
IT (1) | IT1266571B1 (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19510566A1 (de) * | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
FR2745570B1 (fr) | 1996-03-04 | 1998-06-19 | Roussel Uclaf | Nouveaux derives soufres comportant une liaison retroamide, leur procede et intermediaires de preparation, leur application a titre de medicaments, et les compositions pharmaceutiques les renfermant |
SE9901573D0 (sv) | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
US7468390B2 (en) | 2002-01-17 | 2008-12-23 | Novartis Ag | Methods of treatment and pharmaceutical composition |
AR057882A1 (es) | 2005-11-09 | 2007-12-26 | Novartis Ag | Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra |
SI2887961T1 (sl) | 2012-08-24 | 2021-08-31 | Novartis Ag | Zaviralci NEP za zdravljenje bolezni, značilnih po atrialni širitvi ali preoblikovanju |
WO2017033128A1 (en) | 2015-08-25 | 2017-03-02 | Novartis Ag | Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors |
US20180311241A1 (en) | 2015-10-29 | 2018-11-01 | Cadila Healthcare Limited | Pharmaceutical synergistic combination |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1191109B (it) * | 1982-12-03 | 1988-02-24 | Simes | Derivati di acidi aminopiridincarbossilici,loro metodo di sintesi e composizioni farmaceutiche che li contengono |
FR2540495B1 (fr) * | 1983-02-07 | 1986-02-14 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide et de ses homologues, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
DE3467754D1 (de) * | 1983-10-03 | 1988-01-07 | Squibb & Sons Inc | Enkephalinase inhibitors |
FR2611712B1 (fr) * | 1987-02-26 | 1989-06-23 | Roussel Uclaf | Nouveaux derives n-substitues de l'alpha-mercaptomethyl benzene propanamide, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
EP0318859A3 (en) * | 1987-12-03 | 1990-08-16 | Dainippon Pharmaceutical Co., Ltd. | N-substituted mercaptopropanamide derivatives |
US4879309A (en) * | 1988-09-27 | 1989-11-07 | Schering Corporation | Mercapto-acylamino acids as antihypertensives |
EP0361365A1 (en) * | 1988-09-30 | 1990-04-04 | E.R. SQUIBB & SONS, INC. | Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use |
GB9123353D0 (en) * | 1991-11-04 | 1991-12-18 | Fujisawa Pharmaceutical Co | New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
GB2272435A (en) * | 1992-11-16 | 1994-05-18 | Fujisawa Pharmaceutical Co | WS75624 substances from saccharothrix strain |
-
1993
- 1993-07-30 IT IT93MI001723A patent/IT1266571B1/it active IP Right Grant
-
1994
- 1994-07-25 EP EP94111584A patent/EP0636621B1/en not_active Expired - Lifetime
- 1994-07-25 AT AT94111584T patent/ATE150019T1/de not_active IP Right Cessation
- 1994-07-25 DE DE69402004T patent/DE69402004T2/de not_active Expired - Fee Related
- 1994-07-27 US US08/281,105 patent/US5506259A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ITMI931723A0 (it) | 1993-07-30 |
DE69402004D1 (de) | 1997-04-17 |
EP0636621B1 (en) | 1997-03-12 |
EP0636621A1 (en) | 1995-02-01 |
US5506259A (en) | 1996-04-09 |
ATE150019T1 (de) | 1997-03-15 |
ITMI931723A1 (it) | 1995-01-30 |
DE69402004T2 (de) | 1997-06-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970311 |