DE69402004D1 - Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder Erkrankungen - Google Patents
Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder ErkrankungenInfo
- Publication number
- DE69402004D1 DE69402004D1 DE69402004T DE69402004T DE69402004D1 DE 69402004 D1 DE69402004 D1 DE 69402004D1 DE 69402004 T DE69402004 T DE 69402004T DE 69402004 T DE69402004 T DE 69402004T DE 69402004 D1 DE69402004 D1 DE 69402004D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- cardiovascular diseases
- illnesses
- mercapto
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001723A IT1266571B1 (it) | 1993-07-30 | 1993-07-30 | Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69402004D1 true DE69402004D1 (de) | 1997-04-17 |
| DE69402004T2 DE69402004T2 (de) | 1997-06-19 |
Family
ID=11366739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69402004T Expired - Fee Related DE69402004T2 (de) | 1993-07-30 | 1994-07-25 | Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder Erkrankungen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5506259A (de) |
| EP (1) | EP0636621B1 (de) |
| AT (1) | ATE150019T1 (de) |
| DE (1) | DE69402004T2 (de) |
| IT (1) | IT1266571B1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19510566A1 (de) * | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| FR2745570B1 (fr) * | 1996-03-04 | 1998-06-19 | Roussel Uclaf | Nouveaux derives soufres comportant une liaison retroamide, leur procede et intermediaires de preparation, leur application a titre de medicaments, et les compositions pharmaceutiques les renfermant |
| SE9901573D0 (sv) * | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
| US7468390B2 (en) | 2002-01-17 | 2008-12-23 | Novartis Ag | Methods of treatment and pharmaceutical composition |
| AR057882A1 (es) | 2005-11-09 | 2007-12-26 | Novartis Ag | Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra |
| RU2667643C2 (ru) | 2012-08-24 | 2018-09-21 | Новартис Аг | Ингибиторы nep для лечения заболеваний, характеризующихся увеличением или ремоделированием предсердия |
| WO2017033128A1 (en) | 2015-08-25 | 2017-03-02 | Novartis Ag | Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors |
| WO2017072636A1 (en) | 2015-10-29 | 2017-05-04 | Cadila Healthcare Limited | Pharmaceutical synergistic combination |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1191109B (it) * | 1982-12-03 | 1988-02-24 | Simes | Derivati di acidi aminopiridincarbossilici,loro metodo di sintesi e composizioni farmaceutiche che li contengono |
| FR2540495B1 (fr) * | 1983-02-07 | 1986-02-14 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide et de ses homologues, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
| EP0136883B1 (de) * | 1983-10-03 | 1987-11-25 | E.R. Squibb & Sons, Inc. | Enkephalinase Inhibitoren |
| FR2611712B1 (fr) * | 1987-02-26 | 1989-06-23 | Roussel Uclaf | Nouveaux derives n-substitues de l'alpha-mercaptomethyl benzene propanamide, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
| EP0318859A3 (de) * | 1987-12-03 | 1990-08-16 | Dainippon Pharmaceutical Co., Ltd. | N-Substituierte Mercaptopropionamid-Derivate |
| US4879309A (en) * | 1988-09-27 | 1989-11-07 | Schering Corporation | Mercapto-acylamino acids as antihypertensives |
| EP0361365A1 (de) * | 1988-09-30 | 1990-04-04 | E.R. SQUIBB & SONS, INC. | Derivate von Aminobenzoesäure und Aminocyclohexancarbonsäure, Zusammensetzungen und ihre Verwendung |
| GB9123353D0 (en) * | 1991-11-04 | 1991-12-18 | Fujisawa Pharmaceutical Co | New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
| GB2272435A (en) * | 1992-11-16 | 1994-05-18 | Fujisawa Pharmaceutical Co | WS75624 substances from saccharothrix strain |
-
1993
- 1993-07-30 IT IT93MI001723A patent/IT1266571B1/it active IP Right Grant
-
1994
- 1994-07-25 DE DE69402004T patent/DE69402004T2/de not_active Expired - Fee Related
- 1994-07-25 AT AT94111584T patent/ATE150019T1/de not_active IP Right Cessation
- 1994-07-25 EP EP94111584A patent/EP0636621B1/de not_active Expired - Lifetime
- 1994-07-27 US US08/281,105 patent/US5506259A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI931723A1 (it) | 1995-01-30 |
| IT1266571B1 (it) | 1997-01-09 |
| EP0636621A1 (de) | 1995-02-01 |
| US5506259A (en) | 1996-04-09 |
| EP0636621B1 (de) | 1997-03-12 |
| DE69402004T2 (de) | 1997-06-19 |
| ITMI931723A0 (it) | 1993-07-30 |
| ATE150019T1 (de) | 1997-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |