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IS1795B - Hliðstæðar aðferðir til framleiðslu á bensópýran og skyldum LTB4 mótlyfjum - Google Patents

Hliðstæðar aðferðir til framleiðslu á bensópýran og skyldum LTB4 mótlyfjum

Info

Publication number
IS1795B
IS1795B IS3969A IS3969A IS1795B IS 1795 B IS1795 B IS 1795B IS 3969 A IS3969 A IS 3969A IS 3969 A IS3969 A IS 3969A IS 1795 B IS1795 B IS 1795B
Authority
IS
Iceland
Prior art keywords
benzopyran
production
similar methods
ltb4 antagonists
related ltb4
Prior art date
Application number
IS3969A
Other languages
English (en)
Other versions
IS3969A (is
Inventor
Koch Kevin
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS3969A publication Critical patent/IS3969A/is
Publication of IS1795B publication Critical patent/IS1795B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
IS3969A 1992-01-23 1993-01-19 Hliðstæðar aðferðir til framleiðslu á bensópýran og skyldum LTB4 mótlyfjum IS1795B (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82441292A 1992-01-23 1992-01-23

Publications (2)

Publication Number Publication Date
IS3969A IS3969A (is) 1993-07-24
IS1795B true IS1795B (is) 2001-12-18

Family

ID=25241346

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3969A IS1795B (is) 1992-01-23 1993-01-19 Hliðstæðar aðferðir til framleiðslu á bensópýran og skyldum LTB4 mótlyfjum

Country Status (37)

Country Link
US (2) US5552435A (is)
EP (1) EP0623123B1 (is)
JP (1) JP2765757B2 (is)
KR (2) KR0124802B1 (is)
CN (1) CN1041311C (is)
AP (1) AP352A (is)
AT (1) ATE152108T1 (is)
AU (1) AU666896B2 (is)
BG (1) BG62331B1 (is)
BR (1) BR9207061A (is)
CA (1) CA2126752C (is)
CZ (1) CZ282400B6 (is)
DE (1) DE69219364T2 (is)
DK (1) DK0623123T3 (is)
EG (1) EG20202A (is)
FI (1) FI943474A (is)
GR (1) GR3023657T3 (is)
HK (1) HK1000245A1 (is)
HU (1) HU221194B1 (is)
IL (1) IL104386A (is)
IS (1) IS1795B (is)
MX (1) MX9300312A (is)
MY (1) MY109144A (is)
NO (1) NO306508B1 (is)
NZ (1) NZ245735A (is)
OA (1) OA11456A (is)
PH (1) PH30346A (is)
PL (1) PL171003B1 (is)
PT (1) PT101183B (is)
RO (1) RO112031B1 (is)
RU (1) RU2114110C1 (is)
SG (1) SG49813A1 (is)
SK (1) SK280451B6 (is)
TW (1) TW213907B (is)
WO (1) WO1993015067A1 (is)
YU (1) YU48949B (is)
ZA (1) ZA93486B (is)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2084547B1 (es) * 1993-07-12 1997-01-16 Pfizer Antagonistas benzopiranicos y relacionados de leucotrieno b4.
CN1166834A (zh) * 1994-10-13 1997-12-03 美国辉瑞有限公司 苯并吡喃和苯并稠合化合物，其制备方法和它们作为白三烯b4(ltb4)拮抗剂的用途
RU2128655C1 (ru) * 1994-10-13 1999-04-10 Пфайзер Инк. Бензопирановые и бензоконденсированные соединения, промежуточные соединения, фармацевтическая композиция и способ ингибирования
JP3117730B2 (ja) * 1996-09-16 2000-12-18 ファイザー・インク 置換クロマール誘導体を製造するための方法及び中間体
US6416733B1 (en) 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
IL121931A (en) * 1996-10-17 2000-02-17 Pfizer Pharmaceutical compositions for preventing allograft rejection
EP0963755A3 (en) * 1998-04-16 2001-03-14 Pfizer Products Inc. Use of benzopyranes for preventing allograft rejection
US6436987B1 (en) * 2000-06-08 2002-08-20 Pfizer Inc. Crystalline forms of (3S-trans)-2-[3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)-benzoic acid
US6770259B2 (en) 2000-11-03 2004-08-03 Bristol-Myers Squibb Pharma Company Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
WO2002060888A1 (en) * 2001-01-30 2002-08-08 Pfizer Products Inc. Processes for preparing chromanylbenzoic acids
AU4239302A (en) * 2001-06-28 2003-01-02 Pfizer Products Inc. Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
US20080260817A1 (en) * 2004-07-22 2008-10-23 Phenil Jayantilal Patel Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist
WO2017095725A1 (en) 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl sulfonamides as blt1 antagonists
WO2017095723A1 (en) 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists
WO2017095722A1 (en) 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists
US20190382363A1 (en) 2015-11-30 2019-12-19 Merck Sharp & Dohme Corp. Aryl sulfonamides as blt1 antagonists

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2309282A1 (de) * 1973-02-24 1974-08-29 Hoechst Ag Verfahren zur herstellung von 4-hydroxy-thiochromanen
DE2745305A1 (de) * 1977-10-07 1979-04-19 Bayer Ag Insektizide und akarizide mittel
US4565882A (en) * 1984-01-06 1986-01-21 G. D. Searle & Co. Substituted dihydrobenzopyran-2-carboxylates
CA1320490C (en) * 1987-01-12 1993-07-20 Darrel M. Gapinski Anti-inflammatory agents
JPS63292977A (ja) * 1987-05-25 1988-11-30 片山　晋 スキ−用のビンディング固定板
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
US5059609A (en) * 1987-10-19 1991-10-22 Pfizer Inc. Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
WO1990012010A1 (en) * 1989-04-07 1990-10-18 Pfizer Inc. Substituted chromans in the treatment of asthma, arthritis and related diseases
WO1990015801A1 (en) * 1989-06-22 1990-12-27 Pfizer Inc. Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases
WO1991012253A1 (en) * 1990-02-07 1991-08-22 Pfizer Inc. Tetralin and chroman derivatives useful in the treatment of asthma, arthritis, and related diseases
HUT67929A (en) * 1992-01-23 1995-05-29 Pfizer Benzopyran and related ltb4 antagonists
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors
FR2693196B1 (fr) * 1992-07-03 1994-12-23 Lipha Dérivés de benzopyranone ou de benzothiopyranone, procédé de préparation et composition pharmaceutique les contenant.

Also Published As

Publication number Publication date
EP0623123A1 (en) 1994-11-09
NO942759D0 (no) 1994-07-22
MY109144A (en) 1996-12-31
PL171003B1 (pl) 1997-02-28
SK84494A3 (en) 1995-05-10
CA2126752A1 (en) 1993-08-05
AU666896B2 (en) 1996-02-29
JP2765757B2 (ja) 1998-06-18
ZA93486B (en) 1994-07-22
RU94035964A (ru) 1997-05-27
WO1993015067A1 (en) 1993-08-05
IS3969A (is) 1993-07-24
HUT68790A (en) 1995-07-28
EP0623123B1 (en) 1997-04-23
KR950700273A (ko) 1995-01-16
ATE152108T1 (de) 1997-05-15
PT101183B (pt) 1999-09-30
BG62331B1 (bg) 1999-08-31
BG98867A (bg) 1995-03-31
BR9207061A (pt) 1995-12-26
CZ176294A3 (en) 1995-02-15
HK1000245A1 (en) 1998-02-13
PH30346A (en) 1997-04-02
NZ245735A (en) 1995-04-27
DE69219364T2 (de) 1997-08-07
YU3393A (sh) 1996-07-24
AU3065092A (en) 1993-09-01
FI943474A0 (fi) 1994-07-22
NO942759L (no) 1994-07-22
RU2114110C1 (ru) 1998-06-27
AP352A (en) 1994-08-10
EG20202A (en) 1997-10-30
TW213907B (is) 1993-10-01
SG49813A1 (en) 1998-06-15
PT101183A (pt) 1994-03-31
AP9200449A0 (en) 1993-01-31
YU48949B (sh) 2003-01-31
GR3023657T3 (en) 1997-09-30
KR0124802B1 (ko) 1997-11-25
OA11456A (en) 2003-11-18
DE69219364D1 (de) 1997-05-28
JPH07502536A (ja) 1995-03-16
HU9401979D0 (en) 1994-09-28
IL104386A (en) 2001-05-20
NO306508B1 (no) 1999-11-15
IL104386A0 (en) 1993-05-13
CZ282400B6 (cs) 1997-07-16
MX9300312A (es) 1993-07-31
RO112031B1 (ro) 1997-04-30
CN1075318A (zh) 1993-08-18
FI943474A (fi) 1994-07-22
US5552435A (en) 1996-09-03
SK280451B6 (sk) 2000-02-14
US5684046A (en) 1997-11-04
HU221194B1 (en) 2002-08-28
CA2126752C (en) 2000-05-16
DK0623123T3 (da) 1997-10-13
CN1041311C (zh) 1998-12-23

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