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IN2014CN04076A - - Google Patents

Info

Publication number
IN2014CN04076A
IN2014CN04076A IN4076CHN2014A IN2014CN04076A IN 2014CN04076 A IN2014CN04076 A IN 2014CN04076A IN 4076CHN2014 A IN4076CHN2014 A IN 4076CHN2014A IN 2014CN04076 A IN2014CN04076 A IN 2014CN04076A
Authority
IN
India
Application number
Inventor
Matthew Delisa
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Publication of IN2014CN04076A publication Critical patent/IN2014CN04076A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/99Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN4076CHN2014 2011-11-04 2014-05-30 IN2014CN04076A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161555854P 2011-11-04 2011-11-04
PCT/US2012/063590 WO2013067523A1 (en) 2011-11-04 2012-11-05 A prokaryote-based cell-free system for the synthesis of glycoproteins

Publications (1)

Publication Number Publication Date
IN2014CN04076A true IN2014CN04076A (en) 2015-10-23

Family

ID=48192910

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4076CHN2014 IN2014CN04076A (en) 2011-11-04 2014-05-30

Country Status (5)

Country Link
US (2) US11193154B2 (en)
CN (2) CN104080921A (en)
HK (1) HK1202896A1 (en)
IN (1) IN2014CN04076A (en)
WO (1) WO2013067523A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2906671A1 (en) * 2013-03-14 2014-09-25 Glycobia, Inc. Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes
CN106232832B (en) 2013-12-06 2022-04-05 哈佛大学校长及研究员协会 Paper-based synthetic gene networks
CN106574288A (en) * 2014-07-08 2017-04-19 泰克年研究发展基金会公司 Methods and kits for cell-free transcription and translation
CA2971653C (en) * 2014-12-30 2024-06-11 Glaxosmithkline Biologicals S.A. Compositions and methods for protein glycosylation
WO2016134485A1 (en) 2015-02-26 2016-09-01 Vaxalta Inc. Acinetobacter o-oligosaccharyltransferases and uses thereof
CN106478773B (en) * 2015-08-25 2021-09-14 三生国健药业(上海)股份有限公司 Novel artificially synthesized signal peptide
WO2017117539A1 (en) * 2015-12-30 2017-07-06 Northwestern University Cell-free glycoprotein synthesis (cfgps) in prokaryotic cell lysates enriched with components for glycosylation
US10829795B2 (en) * 2016-07-14 2020-11-10 Northwestern University Method for rapid in vitro synthesis of glycoproteins via recombinant production of N-glycosylated proteins in prokaryotic cell lysates
WO2019035916A1 (en) 2017-08-15 2019-02-21 Northwestern University Design of protein glycosylation sites by rapid expression and characterization of n-glycosyltransferases
US11530432B2 (en) 2018-03-19 2022-12-20 Northwestern University Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates
US11725224B2 (en) 2018-04-16 2023-08-15 Northwestern University Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates
AU2019287659A1 (en) 2018-06-16 2021-01-07 Vaxnewmo Llc Glycosylated ComP pilin variants, methods of making and uses thereof
US20220403347A1 (en) 2019-08-09 2022-12-22 Glaxosmithkline Biologicals S.A. Mutated pglb oligosaccharyltransferase enzymes
CA3155758A1 (en) * 2019-10-25 2021-04-29 Michael C. Jewett Cell-free extract preparation protocol for enrichment of membrane vesicles and increased glycoprotein yields
CN115181752B (en) * 2022-07-12 2024-12-24 大连大学 A method for optimizing sugar chain plasmids to improve protein modification efficiency and protein expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4061043B2 (en) * 2000-12-28 2008-03-12 株式会社ポストゲノム研究所 Method for producing peptide etc. by in vitro transcription / translation system
IL163806A0 (en) * 2002-03-07 2005-12-18 Eidgenoess Tech Hochschule System and method for the production of recombinant glycosylated proteins in a prokaryotic host
JP4590249B2 (en) * 2004-11-17 2010-12-01 独立行政法人理化学研究所 Cell-free protein synthesis system for glycoprotein synthesis
KR101589554B1 (en) * 2008-01-03 2016-02-01 코넬 리서치 파운데이션 인코포레이티드 Glycosylated protein expression in prokaryotes
US20100286067A1 (en) * 2008-01-08 2010-11-11 Biogenerix Ag Glycoconjugation of polypeptides using oligosaccharyltransferases

Also Published As

Publication number Publication date
US20220340947A1 (en) 2022-10-27
US20140255987A1 (en) 2014-09-11
CN104080921A (en) 2014-10-01
CN112980907A (en) 2021-06-18
WO2013067523A1 (en) 2013-05-10
US11193154B2 (en) 2021-12-07
HK1202896A1 (en) 2015-10-09

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