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IN2012DN03348A - - Google Patents

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Publication number
IN2012DN03348A
IN2012DN03348A IN3348DEN2012A IN2012DN03348A IN 2012DN03348 A IN2012DN03348 A IN 2012DN03348A IN 3348DEN2012 A IN3348DEN2012 A IN 3348DEN2012A IN 2012DN03348 A IN2012DN03348 A IN 2012DN03348A
Authority
IN
India
Prior art keywords
monoclonal antibodies
methods
progastrin
compositions
present disclosure
Prior art date
Application number
Other languages
English (en)
Inventor
Pannequin Julie
Boudier Laure
Joubert Dominique
Hollande Frederic
Original Assignee
Biorealites
Inst Nat Sante Rech Med
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43086711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN03348(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biorealites, Inst Nat Sante Rech Med, Centre Nat Rech Scient filed Critical Biorealites
Publication of IN2012DN03348A publication Critical patent/IN2012DN03348A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN3348DEN2012 2009-10-16 2010-10-15 IN2012DN03348A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25262509P 2009-10-16 2009-10-16
PCT/EP2010/006329 WO2011045080A2 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses

Publications (1)

Publication Number Publication Date
IN2012DN03348A true IN2012DN03348A (ko) 2015-10-23

Family

ID=43086711

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3348DEN2012 IN2012DN03348A (ko) 2009-10-16 2010-10-15

Country Status (41)

Country Link
US (7) US9611320B2 (ko)
EP (2) EP3421493B1 (ko)
JP (3) JP5985987B2 (ko)
KR (2) KR101640520B1 (ko)
CN (2) CN104628857A (ko)
AP (1) AP2012006262A0 (ko)
AR (1) AR078659A1 (ko)
AU (1) AU2010306119A1 (ko)
BR (1) BR112012008818B1 (ko)
CA (1) CA2777691C (ko)
CL (1) CL2012000914A1 (ko)
CR (1) CR20120184A (ko)
CU (1) CU24196B1 (ko)
CY (1) CY1120913T1 (ko)
DK (1) DK2488551T3 (ko)
EA (2) EA201791876A1 (ko)
EC (1) ECSP12011796A (ko)
ES (2) ES2690943T3 (ko)
GE (1) GEP201706604B (ko)
GT (1) GT201200114A (ko)
HK (1) HK1178183A1 (ko)
HN (1) HN2012000708A (ko)
HR (1) HRP20181645T1 (ko)
IL (2) IL219019B (ko)
IN (1) IN2012DN03348A (ko)
LT (1) LT2488551T (ko)
MA (1) MA33747B1 (ko)
MX (1) MX351635B (ko)
NI (1) NI201200054A (ko)
NZ (2) NZ599971A (ko)
PE (1) PE20121649A1 (ko)
PL (2) PL3421493T3 (ko)
PT (1) PT2488551T (ko)
RS (1) RS57966B1 (ko)
SG (1) SG10201704933PA (ko)
SI (1) SI2488551T1 (ko)
TN (1) TN2012000159A1 (ko)
TW (1) TWI537002B (ko)
UA (1) UA106771C2 (ko)
WO (1) WO2011045080A2 (ko)
ZA (1) ZA201202642B (ko)

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WO2008076454A1 (en) 2006-12-19 2008-06-26 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
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KR101640520B1 (ko) * 2009-10-16 2016-07-19 르 라보레또레 쎄르비에르 프로가스트린에 대한 모노클로날 항체 및 이들의 용도
US8900817B2 (en) * 2010-01-08 2014-12-02 Les Laboratories Servier Progastrin and liver pathologies
US9487582B2 (en) * 2010-01-08 2016-11-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for treating pancreatic cancer
WO2011116954A2 (en) * 2010-03-24 2011-09-29 Bioréalités S.A.S. Prophylaxis of colorectal and gastrointestinal cancer
KR101576174B1 (ko) * 2010-07-26 2015-12-09 르 라보레또레 쎄르비에르 간암 요법을 위한 방법 및 조성물
US8785603B2 (en) 2011-05-20 2014-07-22 Siemens Healthcare Diagnostics Inc. Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
WO2012164035A1 (en) 2011-06-01 2012-12-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the risk of developing a colonic neoplasia
WO2015003114A1 (en) * 2013-07-05 2015-01-08 University Of Washington Through Its Center For Commercialization Soluble mic neutralizing monoclonal antibody for treating cancer
US10023651B2 (en) 2014-04-18 2018-07-17 The Research Foundation For The State University Of New York Humanized anti-TF-antigen antibodies
WO2015161311A2 (en) * 2014-04-18 2015-10-22 The Research Foundation For The State University Of New York Humanized anti-tf-antigen antibodies
WO2016066671A1 (en) 2014-10-29 2016-05-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for treating resistant cancers using progastrin inhibitors
WO2017048629A1 (en) * 2015-09-15 2017-03-23 The Scripps Research Institute Antibodies for generating anti-inflammatory macrophage and related uses
EP3397966B1 (en) * 2015-12-31 2021-09-29 Progastrine et Cancers S.à r.l. Compositions and methods for detecting and treating gastric cancer
JP6962920B2 (ja) * 2015-12-31 2021-11-05 プロガストリン、エ、カンセル、エス、アー エル、エルProgastrine Et Cancers S.A R.L. 卵巣癌の検出および治療のための組成物および方法
MA43550A (fr) * 2015-12-31 2018-11-07 Syncerus S A R L Compositions et procédés d'évaluation du risque d'apparition d'un cancer
WO2018178364A1 (en) * 2017-03-30 2018-10-04 Progastrine Et Cancers S.À R.L. Compositions and methods for treating lung cancer
CA3058263C (en) * 2017-03-30 2023-08-01 Ecs-Progastrin Sa Compositions and methods for detecting prostate cancer
CN111670197A (zh) * 2017-12-05 2020-09-15 普莱戈斯瑞恩癌症有限责任公司 治疗癌症的抗前胃泌激素抗体与免疫疗法的组合疗法
WO2019110845A1 (en) 2017-12-08 2019-06-13 Ecs-Biotracker Sàrl Radiolabeled progastrin in cancer diagnosis
WO2019145537A1 (en) 2018-01-26 2019-08-01 Ecs-Progastrin Sa Combination of progastrin detection with other cancer biomarkers in cancer diagnosis
JP7485274B2 (ja) * 2018-02-27 2024-05-16 イー、シー、エス、プロガストリン、エス、エー 免疫療法のためのバイオマーカーとしてのプロガストリン
TWI793238B (zh) * 2018-12-27 2023-02-21 偉喬生醫股份有限公司 體外檢測生物樣品之胃源性蛋白的方法及套組
CN112062846A (zh) * 2020-04-27 2020-12-11 杭州博茵生物技术有限公司 一种g-17单克隆抗体及其应用
CN115785273B (zh) * 2021-09-10 2023-10-31 东莞市朋志生物科技有限公司 一种抗胃蛋白酶原i的抗体及其应用
CN116143920A (zh) * 2022-12-30 2023-05-23 南京岚煜生物科技有限公司 胃泌素17的单克隆抗体及其细胞株的制备方法和应用
CN117567611B (zh) * 2023-11-22 2024-05-14 艾维可生物科技有限公司 抗成熟型胃泌素17的单克隆抗体及其应用

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WO2011116954A2 (en) * 2010-03-24 2011-09-29 Bioréalités S.A.S. Prophylaxis of colorectal and gastrointestinal cancer

Also Published As

Publication number Publication date
JP6272793B2 (ja) 2018-01-31
US20110117086A1 (en) 2011-05-19
LT2488551T (lt) 2018-10-25
CR20120184A (es) 2012-08-20
MX2012004400A (es) 2012-06-27
PE20121649A1 (es) 2012-12-08
JP2015145380A (ja) 2015-08-13
CU20120060A7 (es) 2013-04-19
US11299542B2 (en) 2022-04-12
GEP201706604B (en) 2017-01-25
PL2488551T3 (pl) 2019-01-31
IL219019B (en) 2019-05-30
TW201119675A (en) 2011-06-16
US20170174761A1 (en) 2017-06-22
AP2012006262A0 (en) 2012-06-30
BR112012008818A2 (pt) 2018-05-22
US10385125B2 (en) 2019-08-20
IL254004A0 (en) 2017-10-31
NZ599971A (en) 2014-12-24
EP3421493C0 (en) 2024-01-17
HN2012000708A (es) 2015-06-22
EP2488551B1 (en) 2018-07-25
NI201200054A (es) 2012-08-20
BR112012008818B1 (pt) 2021-10-19
CA2777691A1 (en) 2011-04-21
US10377821B2 (en) 2019-08-13
NZ701709A (en) 2016-06-24
SG10201704933PA (en) 2017-07-28
CY1120913T1 (el) 2019-12-11
EP3421493B1 (en) 2024-01-17
EA201791876A1 (ru) 2018-01-31
HK1178183A1 (zh) 2013-09-06
GT201200114A (es) 2014-08-11
US20170306011A1 (en) 2017-10-26
US10385126B2 (en) 2019-08-20
CU24196B1 (es) 2016-09-30
MA33747B1 (fr) 2012-11-01
EA201200597A1 (ru) 2012-12-28
CL2012000914A1 (es) 2012-09-14
US20180022802A1 (en) 2018-01-25
ES2973217T3 (es) 2024-06-19
AU2010306119A1 (en) 2012-05-03
PL3421493T3 (pl) 2024-04-29
JP2013507138A (ja) 2013-03-04
AR078659A1 (es) 2011-11-23
CN102791735B (zh) 2016-05-18
SI2488551T1 (sl) 2019-01-31
WO2011045080A3 (en) 2011-07-07
CA2777691C (en) 2018-02-27
RS57966B1 (sr) 2019-01-31
US20220195035A1 (en) 2022-06-23
EA029271B1 (ru) 2018-03-30
US20170306012A1 (en) 2017-10-26
MX351635B (es) 2017-10-23
KR101640520B1 (ko) 2016-07-19
TN2012000159A1 (en) 2013-12-12
US9611320B2 (en) 2017-04-04
KR20150082672A (ko) 2015-07-15
ECSP12011796A (es) 2012-06-29
PT2488551T (pt) 2018-10-31
US10385124B2 (en) 2019-08-20
KR20120091221A (ko) 2012-08-17
UA106771C2 (uk) 2014-10-10
EP2488551A2 (en) 2012-08-22
ES2690943T3 (es) 2018-11-23
HRP20181645T1 (hr) 2018-12-14
CN102791735A (zh) 2012-11-21
JP2017212992A (ja) 2017-12-07
US20200002413A1 (en) 2020-01-02
WO2011045080A2 (en) 2011-04-21
IL219019A0 (en) 2012-06-28
CN104628857A (zh) 2015-05-20
JP5985987B2 (ja) 2016-09-06
ZA201202642B (en) 2013-06-26
EP3421493A1 (en) 2019-01-02
TWI537002B (zh) 2016-06-11
DK2488551T3 (en) 2018-10-08
IL254004B2 (en) 2023-06-01

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