[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IN2012DN02358A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02358A
IN2012DN02358A IN2358DEN2012A IN2012DN02358A IN 2012DN02358 A IN2012DN02358 A IN 2012DN02358A IN 2358DEN2012 A IN2358DEN2012 A IN 2358DEN2012A IN 2012DN02358 A IN2012DN02358 A IN 2012DN02358A
Authority
IN
India
Prior art keywords
silk
active agents
microparticles
present
compositions
Prior art date
Application number
Other languages
English (en)
Inventor
Xiaoqin Wang
David L Kaplan
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College filed Critical Tufts College
Publication of IN2012DN02358A publication Critical patent/IN2012DN02358A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
IN2358DEN2012 2009-09-29 2010-09-29 IN2012DN02358A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24667609P 2009-09-29 2009-09-29
PCT/US2010/050698 WO2011041395A2 (fr) 2009-09-29 2010-09-29 Nanosphères et microsphères de soie et leurs procédés de fabrication

Publications (1)

Publication Number Publication Date
IN2012DN02358A true IN2012DN02358A (fr) 2015-08-21

Family

ID=43826861

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2358DEN2012 IN2012DN02358A (fr) 2009-09-29 2010-09-29

Country Status (7)

Country Link
US (2) US8715740B2 (fr)
EP (1) EP2483199B1 (fr)
JP (1) JP5730317B2 (fr)
CA (1) CA2774643A1 (fr)
IL (1) IL218654A (fr)
IN (1) IN2012DN02358A (fr)
WO (1) WO2011041395A2 (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6092337A (ja) * 1983-10-26 1985-05-23 Sekisui Plastics Co Ltd 発泡フエノ−ル樹脂成形物の製造方法
EP2650907B1 (fr) 2004-06-04 2024-10-23 The Board Of Trustees Of The University Of Illinois Procedes et dispositifs permettant de fabriquer et d'assembler des elements a semiconducteur imprimables
US20100096763A1 (en) 2006-11-03 2010-04-22 Trustees Of Tufts College Biopolymer optofluidic device and method of manufacturing the same
WO2008127402A2 (fr) 2006-11-03 2008-10-23 Trustees Of Tufts College Capteur de biopolymère et procédé de fabrication de celui-ci
WO2008127404A2 (fr) 2006-11-03 2008-10-23 Trustees Of Tufts College Dispositif optique de biopolymère à nanomotifs et procédé de fabrication de celui-ci
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
EP2349440B1 (fr) 2008-10-07 2019-08-21 Mc10, Inc. Ballonnet de cathéter comportant un circuit intégré étirable et un réseau de détecteurs
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
JP2013506058A (ja) 2009-09-28 2013-02-21 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ 延伸したシルクegel繊維およびその製造方法
IN2012DN02358A (fr) * 2009-09-29 2015-08-21 Tufts College
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
WO2011084450A1 (fr) 2009-12-16 2011-07-14 The Board Of Trustees Of The University Of Illinois Électrophysiologie in vivo faisant intervenir des équipements électroniques conformes
KR101837481B1 (ko) 2010-03-17 2018-03-13 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 생체흡수성 기판 상 이식가능한 바이오의료 장치
JP2013542181A (ja) 2010-09-03 2013-11-21 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ プラズモンナノ粒子ドープ絹材料
US20140287043A1 (en) * 2011-04-21 2014-09-25 Trustees Of Tufts College Compositions and methods for stabilization of active agents
US9765934B2 (en) 2011-05-16 2017-09-19 The Board Of Trustees Of The University Of Illinois Thermally managed LED arrays assembled by printing
KR102000302B1 (ko) 2011-05-27 2019-07-15 엠씨10, 인크 전자, 광학, 및/또는 기계 장치 및 시스템, 그리고 이를 제조하기 위한 방법
EP2713863B1 (fr) 2011-06-03 2020-01-15 The Board of Trustees of the University of Illionis Réseau d'électrodes de surface conformables, multiplexées de manière active et à haute densité, pour un interfaçage avec le cerveau
CN102344686A (zh) * 2011-08-02 2012-02-08 北京汇亨创管理咨询有限公司 一种以聚乙烯醇为稳定剂的丝素蛋白纳米颗粒的制备方法
CN104472023B (zh) 2011-12-01 2018-03-27 伊利诺伊大学评议会 经设计以经历可编程转变的瞬态器件
EP2811987B1 (fr) 2012-02-06 2021-01-20 Children's Medical Center Corporation Biomatériau multicouche destiné à la régénération de tissus et la cicatrisation de plaies
US9554989B2 (en) 2012-03-20 2017-01-31 Trustees Of Tufts College Silk reservoirs for drug delivery
WO2013149181A1 (fr) 2012-03-30 2013-10-03 The Board Of Trustees Of The University Of Illinois Dispositifs électroniques montables sur des appendices et conformables à des surfaces
WO2013152265A1 (fr) 2012-04-06 2013-10-10 Trustees Of Tufts College Procédés de production et d'utilisation de microfibres de soie
WO2014021954A2 (fr) * 2012-04-13 2014-02-06 Trustees Of Tufts College Matières à base de fibroïne de soie magnéto-sensible
JP2015512944A (ja) * 2012-04-13 2015-04-30 トラスティーズ・オブ・タフツ・カレッジTrustees Of Tufts College 絹マイクロスフェアを調製するための方法および組成物
US10653786B2 (en) 2012-04-25 2020-05-19 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
WO2014012105A1 (fr) * 2012-07-13 2014-01-16 Tufts University Encapsulation de phases non miscibles dans des biomatières de fibroïne de soie
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
EP3412682B1 (fr) 2013-03-15 2022-08-31 Trustees Of Tufts College Compositions de soie à faible poids moléculaire et compositions de soie de stabilisation
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10285702B2 (en) 2013-04-24 2019-05-14 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
EP3016634A2 (fr) * 2013-07-05 2016-05-11 Therakine Biodelivery GmbH Composition d'administration de médicament pour applications topiques et injections et formulations ophtalmiques, procédés de fabrication associés et procédés d'administration d'une composition d'administration de médicament
SG11201510659TA (en) 2013-07-19 2016-01-28 Univ Singapore Tissue interface augmentation device for ligament/tendon reconstruction
WO2015048433A1 (fr) * 2013-09-27 2015-04-02 Tufts University Synthèse de sphères de taille micronique et submicronique de fibroïne de soie au moyen d'un procédé à écoulement descendant
WO2015048527A1 (fr) 2013-09-27 2015-04-02 Tufts University Hydrogels de soie optiquement transparents
BR112016006898A8 (pt) 2013-09-30 2020-02-18 Silk Therapeutics Inc composição, filmes, método de redução de linhas finas e rugas, géis, método de suavização e rejuvenescimento da pele humana, soro, método de hidratação da pele humana, composição de descamação da pele e método para a preparação de uma solução
JP6135486B2 (ja) * 2013-12-06 2017-05-31 豊田合成株式会社 樹脂成形体
CN113564927A (zh) 2014-12-02 2021-10-29 丝绸医疗公司 丝性能服装和产品及其制备方法
US11260012B2 (en) 2015-01-12 2022-03-01 Evolved By Nature, Inc. Preserved silk protein fragment compositions and articles manufactured therefrom
CN107851208B (zh) 2015-06-01 2021-09-10 伊利诺伊大学评议会 具有无线供电和近场通信能力的小型化电子系统
EP3304130B1 (fr) 2015-06-01 2021-10-06 The Board of Trustees of the University of Illinois Approche alternative de détection d'uv
AU2016294611B2 (en) 2015-07-14 2022-08-11 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
US10925543B2 (en) 2015-11-11 2021-02-23 The Board Of Trustees Of The University Of Illinois Bioresorbable silicon electronics for transient implants
CN105297289B (zh) * 2015-12-07 2017-10-31 清华大学深圳研究生院 一种丝素蛋白储能调温纤维膜制备方法
CN105963275B (zh) * 2016-05-31 2019-05-17 中国医学科学院生物医学工程研究所 壳层可控的丝素蛋白微囊及制备方法
CN109789218A (zh) 2016-06-23 2019-05-21 菲吉乐科(加拿大)有限公司 噬菌体的微囊化和相关产品
US11413319B2 (en) 2016-06-23 2022-08-16 Phagelux (Canada) Inc. Microencapsulation of bacteriophages and related products
WO2018026853A1 (fr) 2016-08-01 2018-02-08 Trustees Of Tufts College Fabrication assistée par tension mécanique biomimétique d'une architecture nanofibrillaire
US10857262B2 (en) 2016-10-31 2020-12-08 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
KR101957013B1 (ko) * 2017-04-04 2019-03-11 서울대학교산학협력단 골 형성 단백질을 포함하는 약물 전달체 및 그 제조 방법
US11390988B2 (en) 2017-09-27 2022-07-19 Evolved By Nature, Inc. Silk coated fabrics and products and methods of preparing the same
US11794161B1 (en) 2018-11-21 2023-10-24 Trucapsol, Llc Reduced permeability microcapsules
US11571674B1 (en) 2019-03-28 2023-02-07 Trucapsol Llc Environmentally biodegradable microcapsules
US11542392B1 (en) 2019-04-18 2023-01-03 Trucapsol Llc Multifunctional particle additive for enhancement of toughness and degradation in biodegradable polymers
CN110327307B (zh) * 2019-06-26 2020-06-23 浙江大学 一种丝素载药纳米微囊的制备方法及产品
CN110483830B (zh) * 2019-07-31 2021-08-17 武汉纺织大学 超轻高弹丝素微纳米纤维气凝胶及其制备方法与应用
WO2021076798A1 (fr) 2019-10-15 2021-04-22 Sofregen Medical, Inc. Dispositifs de distribution pour l'administration et procédés de distribution de compositions
US11547978B2 (en) 2020-01-30 2023-01-10 Trucapsol Llc Environmentally biodegradable microcapsules
CN111454468B (zh) * 2020-03-27 2021-04-20 西安交通大学 一种形状可控的智能响应微球及其制备方法
WO2022026495A1 (fr) * 2020-07-28 2022-02-03 University Of Georgia Research Foundation, Inc. Nanoparticules de soie antimicrobiennes et leurs procédés de fabrication et méthodes d'utilisation
US11878280B2 (en) 2022-04-19 2024-01-23 Trucapsol Llc Microcapsules comprising natural materials
CN115414533B (zh) * 2022-09-20 2024-02-23 中国人民解放军总医院第一医学中心 一种模拟膀胱壁生理结构的组织工程支架及其制备方法
US11904288B1 (en) 2023-02-13 2024-02-20 Trucapsol Llc Environmentally biodegradable microcapsules
US11969491B1 (en) 2023-02-22 2024-04-30 Trucapsol Llc pH triggered release particle

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE380083A (fr) 1929-12-23
US3424164A (en) 1966-05-20 1969-01-28 Ethicon Inc Silk suture
JPS5838449B2 (ja) 1979-04-17 1983-08-23 カネボウ株式会社 微粉末状絹フィプロインの製造法
JPS56166235A (en) 1980-05-24 1981-12-21 Kanebo Ltd Hydrophilic porous body and its preparation
JPS5838449A (ja) 1981-08-31 1983-03-05 Matsushita Electronics Corp 高圧ナトリウムランプ装置
JPS60142259A (ja) 1983-12-29 1985-07-27 Kanebo Ltd 固定化抗体
JPS60259677A (ja) 1984-05-31 1985-12-21 水島 繁三郎 動物蛋白吸着再生繊維からなる原糸、織物、編物及びその製造方法
CA1340581C (fr) 1986-11-20 1999-06-08 Joseph P. Vacanti Neomorphogenese chimerique d'organes par implatation cellulaire controlee, utilisant des matrices artificielles
JPS63190604A (ja) 1987-02-03 1988-08-08 Agency Of Ind Science & Technol 新規の水−アルコ−ル分離膜
US5606019A (en) 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
JPH0694518B2 (ja) 1987-11-02 1994-11-24 工業技術院長 絹フィブロイン多孔質体の製造方法
GB8800078D0 (en) 1988-01-05 1988-02-10 Ciba Geigy Ag Novel antibodies
JPH0669485B2 (ja) * 1988-10-19 1994-09-07 住江織物株式会社 シルクフィブロイン含有成形物
US5290494A (en) 1990-03-05 1994-03-01 Board Of Regents, The University Of Texas System Process of making a resorbable implantation device
US5989894A (en) 1990-04-20 1999-11-23 University Of Wyoming Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA
JPH04263611A (ja) 1991-02-16 1992-09-18 Pola Chem Ind Inc 水不溶性固形フィブロイン成形物及びその製造法
JPH06346314A (ja) 1993-06-02 1994-12-20 Toyobo Co Ltd 再生絹フィブロイン繊維およびその製造方法
JPH08295697A (ja) 1995-04-26 1996-11-12 Kanebo Ltd 高濃度絹フィブロイン水溶液の製造方法
JPH1036676A (ja) 1996-07-26 1998-02-10 Kanebo Ltd タンパク質水溶液の濃縮方法
JP2990239B2 (ja) 1997-06-18 1999-12-13 農林水産省蚕糸・昆虫農業技術研究所長 絹フィブロインおよび絹セリシンを主成分とする創傷被覆材並びにその製造方法
EP1006945A1 (fr) 1997-07-01 2000-06-14 Brown University Research Foundation Dispositifs prothetiques implantables enrobes de molecules bioactives
US6123819A (en) 1997-11-12 2000-09-26 Protiveris, Inc. Nanoelectrode arrays
US5994099A (en) 1997-12-31 1999-11-30 The University Of Wyoming Extremely elastic spider silk protein and DNA coding therefor
US6110590A (en) 1998-04-15 2000-08-29 The University Of Akron Synthetically spun silk nanofibers and a process for making the same
US6196358B1 (en) 1998-07-08 2001-03-06 Shimano Inc. Detachable fluid cooling system for bicycle disc brake
US20030007991A1 (en) 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
JP3151665B2 (ja) 1999-03-23 2001-04-03 農林水産省蚕糸・昆虫農業技術研究所長 生体高分子/ポリアリルアミン複合体およびその製造方法
WO2001036531A1 (fr) 1999-11-15 2001-05-25 Zaidan-Houjin Ueda Sen-I Kagaku Shinkoukai Materiau polymere moleculairement composite en fibroine/cellulose et procede de production de ce materiau
CA2398635A1 (fr) 2000-02-03 2001-08-09 Nexia Biotechnologies, Inc. Fil de suture chirurgical a base de soie d'araignee
IT1316885B1 (it) 2000-10-02 2003-05-13 Consorzio Per Gli Studi Uni Procedimento per la preparazione di un tessuto non tessuto in fibroinadi seta.
JP2002128691A (ja) 2000-10-24 2002-05-09 National Institute Of Agrobiological Sciences セリシン含有素材、その製造方法およびその使用方法
CN1247837C (zh) 2001-03-14 2006-03-29 东京农工大学长代表的日本国 丝和丝样材料的纤维和薄膜的制造方法
ITVR20010098A1 (it) 2001-09-11 2003-03-11 Consorzio Per Gli Studi Uni Procedimento per l'ottenimento di idrogeli di fibroina di seta.
US20030068446A1 (en) 2001-10-02 2003-04-10 Northwestern University Protein and peptide nanoarrays
GB0126118D0 (en) 2001-10-31 2002-01-02 Vollrath Friedrich W L Precursor feedstock for forming filaments
US6902932B2 (en) 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
KR20040071707A (ko) 2001-12-07 2004-08-12 루미리즈 라이팅 유에스 엘엘씨 조명 시스템 및 디스플레이 디바이스
JP3803962B2 (ja) 2001-12-28 2006-08-02 独立行政法人科学技術振興機構 絹タンパク質フィルムとその製造方法
US7057023B2 (en) 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
JP3772207B2 (ja) 2002-06-19 2006-05-10 独立行政法人農業生物資源研究所 生分解性生体高分子材料、その製造方法、およびこの高分子材料からなる機能性素材
EP2447055B1 (fr) 2002-06-24 2017-12-06 Tufts University Biomatériaux en soie et leurs procédés d'utilisation
CA2504327C (fr) 2002-11-01 2012-01-03 Trustees Of Tufts College Gels smectiques de soie native a templates
WO2004062697A2 (fr) 2003-01-07 2004-07-29 Tufts University Matières de fibroïne de soie et utilisation de celles-ci
EP1613796B1 (fr) 2003-04-10 2017-03-22 Tufts University Solution aqueuse concentree de fibroine et utilisation
WO2005000483A1 (fr) 2003-06-06 2005-01-06 Tufts University Procede de formation d'enrobages inorganiques
US8178656B2 (en) 2004-06-11 2012-05-15 Trustees Of Tufts College Silk-based drug delivery system
US7960509B2 (en) 2005-01-14 2011-06-14 Trustees Of Tufts College Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
US9290579B2 (en) 2005-04-20 2016-03-22 Trustees Of Tufts College Covalently immobilized protein gradients in three-dimensional porous scaffolds
ES2374428T3 (es) 2005-08-02 2012-02-16 Trustees Of Tufts College Métodos para la deposición progresiva de recubrimientos de fibroína de seda.
GB0516846D0 (en) 2005-08-17 2005-09-21 Knight David P Meniscal repair device
DE102005043609A1 (de) * 2005-09-13 2007-03-22 Technische Universität München Verfahren und Vorrichtung zur Herstellung eines Fadens aus Seidenproteinen
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
US20110121485A1 (en) 2006-10-30 2011-05-26 Spintec Engineering Gmbh Method and apparatus for the manufacture of a fiber
WO2008127405A2 (fr) 2006-11-03 2008-10-23 Trustees Of Tufts College Dispositif microfluidique avec un microcanal cylindrique et un procédé de fabrication de celui-ci
US20100096763A1 (en) 2006-11-03 2010-04-22 Trustees Of Tufts College Biopolymer optofluidic device and method of manufacturing the same
WO2008127404A2 (fr) 2006-11-03 2008-10-23 Trustees Of Tufts College Dispositif optique de biopolymère à nanomotifs et procédé de fabrication de celui-ci
US20100046902A1 (en) 2006-11-03 2010-02-25 Trustees Of Tufts College Biopolymer photonic crystals and method of manufacturing the same
WO2008127402A2 (fr) 2006-11-03 2008-10-23 Trustees Of Tufts College Capteur de biopolymère et procédé de fabrication de celui-ci
WO2008106485A2 (fr) 2007-02-27 2008-09-04 Trustees Of Tufts College Organes de soie produits par génie tissulaire
CA2688431C (fr) 2007-05-29 2016-07-05 Trustees Of Tufts College Procede de gelification de la fibroine de soie a l'aide de la sonication
WO2009023615A1 (fr) 2007-08-10 2009-02-19 Trustees Of Tufts College Compositions de soie tubulaires et procédés d'utilisation de celles-ci
EP2206017B1 (fr) 2007-11-05 2019-02-20 Trustees Of Tufts College Fabrication de structures photoniques de fibroïne de soie par impression par nanocontact
CA2713251A1 (fr) 2008-02-07 2009-08-13 Trustees Of Tufts College Compositions d'hydroxyapatite et de soie en trois dimensions
US8206774B2 (en) 2008-03-13 2012-06-26 Trustees Of Tufts College Diazonium salt modification of silk polymer
WO2009126689A2 (fr) 2008-04-08 2009-10-15 Trustees Of Tufts College Système et procédé pour fabriquer des structures de biomatériau
JP5727366B2 (ja) 2008-05-15 2015-06-03 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ 絹ポリマーに基づくアデノシン放出:てんかんに対する潜在的治療能力
US20090297588A1 (en) 2008-05-28 2009-12-03 Spin'tec Engineering Gmbh Antibiotic dressing for the treatment of infected wounds
US20110135697A1 (en) 2008-06-18 2011-06-09 Trustees Of Tufts College Edible holographic silk products
GB2461125A (en) 2008-06-25 2009-12-30 Spintec Engineering Gmbh A silk membrane for bone graft material
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
GB2464348A (en) 2008-10-17 2010-04-21 Spintec Engineering Gmbh Applying a liquid protein onto a permeable surface, and silk mono-filament having specific properties
EP2253336A1 (fr) 2009-05-15 2010-11-24 Spintec Engineering GmbH Dispositif médical en soie avec des propriétés antimicrobiennes et son procédé de préparation
JP2012532614A (ja) 2009-07-10 2012-12-20 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ バイオ絹糸タンパク質ベース核酸送達システム
IN2012DN02358A (fr) * 2009-09-29 2015-08-21 Tufts College

Also Published As

Publication number Publication date
US20150056293A1 (en) 2015-02-26
JP2013506007A (ja) 2013-02-21
EP2483199A2 (fr) 2012-08-08
US9381164B2 (en) 2016-07-05
IL218654A (en) 2015-08-31
WO2011041395A2 (fr) 2011-04-07
WO2011041395A3 (fr) 2011-08-25
EP2483199B1 (fr) 2017-04-26
US8715740B2 (en) 2014-05-06
EP2483199A4 (fr) 2013-10-16
JP5730317B2 (ja) 2015-06-10
US20120187591A1 (en) 2012-07-26
IL218654A0 (en) 2012-05-31
CA2774643A1 (fr) 2011-04-07

Similar Documents

Publication Publication Date Title
IN2012DN02358A (fr)
Mandal et al. A Novel Approach on Micro Sponges Drug Delivery System: Method of Preparations, Application, and its Future Prospective
Yan et al. Biocompatible core–shell electrospun nanofibers as potential application for chemotherapy against ovary cancer
Akhgari et al. A review on electrospun nanofibers for oral drug delivery.
NZ609840A (en) Process for making multiparticulate gastroretentive dosage forms
US20090137688A1 (en) Pharmaceutical product
EP3190881A1 (fr) Composites polymères antimicrobiens et biologiquement actifs et méthodes, matériels et dispositifs associés
PE20071139A1 (es) Formulacion de liberacion sostenida que comprende octreotida y dos o mas polimeros de polilactido-co-glicolido
JP2016539953A5 (fr)
Wang et al. Biomimic Trained Immunity‐MSCs Delivery Microcarriers for Acute Liver Failure Regeneration
AR103981A1 (es) Métodos y composiciones particularmente para el tratamiento del trastorno por déficit de atención
WO2012053785A3 (fr) Pastilles à libération prolongée contenant du tacrolimus à titre de principe actif
EP2315571A1 (fr) Procédé pour préparer des microparticules contenant des peptides bioactifs
CN106456557B (zh) 在感染的治疗中使用的治疗剂
CN105079876A (zh) 一种多孔载药复合微球支架材料及其制备方法和应用
US10238663B2 (en) Extended-release drug delivery compositions
Il Kim et al. In situ biosynthesis of a metal nanoparticle encapsulated in alginate gel for imageable drug-delivery system
Zaid et al. Formulation and characterization of combretastatin A4 loaded PLGA nanoparticles
CN108434119B (zh) 一种蛋白口服微囊制剂的制备方法
Raichur et al. Hollow polymeric (PLGA) nano capsules synthesized using solvent emulsion evaporation method for enhanced drug encapsulation and release efficiency
JP2014218464A (ja) 均一分散可能な架橋ゼラチン粒子集合体
US20110256231A1 (en) Method for preparing a micro-particle drug in hemisphere-shaped dosage form and applications thereof
Yousaf et al. Silymarin-laden PVP-nanocontainers prepared via the electrospraying technique for improved aqueous solubility and dissolution rate
WO2012064087A3 (fr) Composition pharmaceutique comprenant des microsphères de polymère contenant de l'anastrozole en tant que principe actif
NZ596275A (en) Burst drug release compositions