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IL94317A - Substituted aminoalkylphosphinic acids, their production and pharmaceutical compositions containing them - Google Patents

Substituted aminoalkylphosphinic acids, their production and pharmaceutical compositions containing them

Info

Publication number
IL94317A
IL94317A IL94317A IL9431790A IL94317A IL 94317 A IL94317 A IL 94317A IL 94317 A IL94317 A IL 94317A IL 9431790 A IL9431790 A IL 9431790A IL 94317 A IL94317 A IL 94317A
Authority
IL
Israel
Prior art keywords
methyl
hydroxy
denotes
phosphinic acid
hydrogen
Prior art date
Application number
IL94317A
Other languages
English (en)
Other versions
IL94317A0 (en
Inventor
Roger Graham Dr Hall
Ludwig Dr Maier
Wolfgang Dr Froestl
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL94317A0 publication Critical patent/IL94317A0/xx
Publication of IL94317A publication Critical patent/IL94317A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36Amides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301Acyclic saturated acids which can have further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Luminescent Compositions (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL94317A 1989-05-13 1990-05-07 Substituted aminoalkylphosphinic acids, their production and pharmaceutical compositions containing them IL94317A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911017A GB8911017D0 (en) 1989-05-13 1989-05-13 Substituted aminoalkylphosphinic acids

Publications (2)

Publication Number Publication Date
IL94317A0 IL94317A0 (en) 1991-03-10
IL94317A true IL94317A (en) 1997-07-13

Family

ID=10656689

Family Applications (1)

Application Number Title Priority Date Filing Date
IL94317A IL94317A (en) 1989-05-13 1990-05-07 Substituted aminoalkylphosphinic acids, their production and pharmaceutical compositions containing them

Country Status (24)

Country Link
EP (1) EP0399949B1 (pt)
JP (1) JP2930366B2 (pt)
KR (1) KR0159501B1 (pt)
AT (1) ATE121095T1 (pt)
AU (1) AU629335B2 (pt)
CA (1) CA2016631C (pt)
DD (1) DD294265A5 (pt)
DE (1) DE69018514T2 (pt)
DK (1) DK0399949T3 (pt)
ES (1) ES2070303T3 (pt)
FI (1) FI94416C (pt)
GB (1) GB8911017D0 (pt)
GR (1) GR3015770T3 (pt)
HR (1) HRP940178A2 (pt)
HU (1) HU206885B (pt)
IE (1) IE66165B1 (pt)
IL (1) IL94317A (pt)
MX (1) MX20639A (pt)
NO (1) NO176761C (pt)
NZ (1) NZ233647A (pt)
PT (1) PT94014B (pt)
SI (1) SI9010917B (pt)
YU (1) YU91790A (pt)
ZA (1) ZA903611B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
AU714980B2 (en) 1996-07-24 2000-01-13 Warner-Lambert Company Llc Isobutylgaba and its derivatives for the treatment of pain
EP1095050A1 (de) 1998-07-15 2001-05-02 Hassan Jomaa Phosphororganische verbindungen und ihre verwendung
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
SE9904507D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
AR033779A1 (es) 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
SE0102055D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
EP1968947A1 (en) 2005-12-23 2008-09-17 AstraZeneca AB Gaba-b receptor modulators
BRPI0620372A2 (pt) 2005-12-23 2011-11-08 Astrazeneca Ab composto, composição farmaceutica, e, uso de um composto
DE102008056228A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
CN103228142A (zh) 2010-09-28 2013-07-31 加利福尼亚大学董事会 治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3311475C1 (de) * 1983-03-29 1984-08-16 Siemens AG, 1000 Berlin und 8000 München Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) * 1983-04-02 1984-10-04 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) * 1987-12-04 1988-01-13 Ciba Geigy Ag Chemical compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
SI9010917A (en) 1997-06-30
IE901716L (en) 1990-11-13
NZ233647A (en) 1992-08-26
HUT53656A (en) 1990-11-28
JPH0395195A (ja) 1991-04-19
HU903012D0 (en) 1990-09-28
FI94416C (fi) 1995-09-11
EP0399949B1 (en) 1995-04-12
ZA903611B (en) 1991-02-27
IE66165B1 (en) 1995-12-13
PT94014A (pt) 1991-01-08
CA2016631C (en) 2000-08-29
NO902109L (no) 1990-11-14
DE69018514D1 (de) 1995-05-18
ATE121095T1 (de) 1995-04-15
GR3015770T3 (en) 1995-07-31
HU206885B (en) 1993-01-28
IL94317A0 (en) 1991-03-10
DD294265A5 (de) 1991-09-26
DK0399949T3 (da) 1995-07-03
SI9010917B (sl) 1999-10-31
AU629335B2 (en) 1992-10-01
CA2016631A1 (en) 1990-11-13
KR900018124A (ko) 1990-12-20
FI94416B (fi) 1995-05-31
YU91790A (sh) 1992-07-20
PT94014B (pt) 1996-12-31
HRP940178A2 (en) 1996-08-31
GB8911017D0 (en) 1989-06-28
MX20639A (es) 1993-12-01
ES2070303T3 (es) 1995-06-01
EP0399949A1 (en) 1990-11-28
FI902368A0 (fi) 1990-05-11
DE69018514T2 (de) 1995-09-21
KR0159501B1 (ko) 1999-01-15
NO902109D0 (no) 1990-05-11
NO176761C (no) 1995-05-24
AU5480990A (en) 1990-11-15
JP2930366B2 (ja) 1999-08-03
NO176761B (no) 1995-02-13

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