IL127153A0 - Fragments of leptin (ob protein) - Google Patents

Fragments of leptin (ob protein)

Info

Publication number: IL127153A0
Authority: IL; Israel
Prior art keywords: leptin; fragments; protein
Prior art date: 1996-06-06

Application number

IL12715397A

Other languages

English (en)

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-06

Filing date

1997-06-04

Publication date

1999-09-22

1996-06-06 Priority claimed from GBGB9611775.9A external-priority patent/GB9611775D0/en

1996-09-05 Priority claimed from GBGB9618540.0A external-priority patent/GB9618540D0/en

1997-02-20 Priority claimed from GBGB9703493.8A external-priority patent/GB9703493D0/en

1997-06-04 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1999-09-22 Publication of IL127153A0 publication Critical patent/IL127153A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Child & Adolescent Psychology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IL12715397A 1996-06-06 1997-06-04 Fragments of leptin (ob protein) IL127153A0 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9611775.9A GB9611775D0 (en)	1996-06-06	1996-06-06	Novel compounds
GBGB9618540.0A GB9618540D0 (en)	1996-09-05	1996-09-05	Novel compounds
GBGB9703493.8A GB9703493D0 (en)	1997-02-20	1997-02-20	Novel compounds
PCT/EP1997/002968 WO1997046585A2 (en)	1996-06-06	1997-06-04	Fragments of leptin (ob protein)

Publications (1)

Publication Number	Publication Date
IL127153A0 true IL127153A0 (en)	1999-09-22

Family

ID=27268305

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12715397A IL127153A0 (en)	1996-06-06	1997-06-04	Fragments of leptin (ob protein)

Country Status (15)

Country	Link
EP (1)	EP0912609A2 (cs)
JP (1)	JP2000512137A (cs)
KR (1)	KR20000016402A (cs)
CN (1)	CN1221426A (cs)
AR (1)	AR008765A1 (cs)
AU (1)	AU3337297A (cs)
BR (1)	BR9709529A (cs)
CA (1)	CA2257240A1 (cs)
CZ (1)	CZ397898A3 (cs)
IL (1)	IL127153A0 (cs)
NO (1)	NO985683L (cs)
NZ (1)	NZ332879A (cs)
PL (1)	PL330361A1 (cs)
TR (1)	TR199802534T2 (cs)
WO (1)	WO1997046585A2 (cs)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000007014A2 (en)	1998-07-28	2000-02-10	Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw	Leptin-mediated gene-induction
US6777388B1 (en) *	1998-08-21	2004-08-17	Clf Medical Technology Acceleration Program, Inc.	Leptin-related peptides
US7208572B2 (en) *	1998-08-21	2007-04-24	Albany Medical College	Leptin-related peptides
US6420339B1 (en)	1998-10-14	2002-07-16	Amgen Inc.	Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
EP1214351A2 (en) *	1999-09-22	2002-06-19	Genset	Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases
CA2407872C (en)	2000-05-22	2013-11-12	Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw	Receptor-based interaction trap
DE60237100D1 (de)	2001-10-22	2010-09-02	Amgen Inc	Verwendung von leptin zur behandlung von lipoatropr prädisposition gegenüber der behandlung
ATE390144T1 (de)	2003-09-08	2008-04-15	Serono Lab	Behandlung von fibrosen
CN1961000B (zh)	2004-02-11	2011-05-04	安米林药品公司	具有可选择特性的杂合多肽
EP1812038A1 (en)	2004-11-18	2007-08-01	VIB vzw	Fibronectin iii domain as leptin receptor antagonists
CA2597649A1 (en)	2005-02-11	2006-08-17	Amylin Pharmaceuticals, Inc.	Gip analog and hybrid polypeptides with selectable properties
US7629315B2 (en)	2005-03-09	2009-12-08	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Compositions for blocking the inhibitory effect of human CRP on human leptin
BRPI0614649A2 (pt)	2005-08-11	2011-04-12	Amylin Pharmaceuticals Inc	polipeptìdeos hìbridos com propriedades selecionáveis
EP1922336B1 (en)	2005-08-11	2012-11-21	Amylin Pharmaceuticals, LLC	Hybrid polypeptides with selectable properties
ES2319048B1 (es) *	2007-06-20	2010-02-10	Universitat De Les Illes Balears	Uso de leptina en el tratamiento de alteraciones en los habitos alimentarios.
US8889622B2 (en)	2007-07-25	2014-11-18	Washington University	Methods of inhibiting seizure in a subject
GB2451858A (en) *	2007-08-15	2009-02-18	Sergiy Konovchuk	Methods of reducing body fat and treating obesity
US20110059969A1 (en)	2007-12-05	2011-03-10	Astrazeneca Ab	Piperazines as anti-obesity agents
WO2009071668A2 (en)	2007-12-05	2009-06-11	Biovitrum Ab (Publ)	Piperazine derivatives and their use as leptin receptor modulators
BRPI0913448A2 (pt) *	2008-06-04	2015-12-01	Astrazeneca Ab	composto, formulação farmacêutica, uso de um composto, e, método para o tratamento ou prevenção das condições ou doenças que são prevenidas, tratadas, ou melhoradas pela ação seletiva por intermédio do receptor de leptina0.
CN102245183A (zh) *	2008-06-04	2011-11-16	阿斯利康(瑞典)有限公司	新化合物v
EP2416797A4 (en)	2009-04-10	2013-04-24	Amylin Pharmaceuticals Llc	AMYLINAGONIST COMPOUNDS FOR OXYGEN ANIMAL MICE
US9475839B2 (en) *	2010-05-11	2016-10-25	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Peptide-based inhibitor of interleukin-10 or interferon-gamma signaling
EP2621519B1 (en)	2010-09-28	2017-06-28	Aegerion Pharmaceuticals, Inc.	Leptin-abd fusion polypeptides with enhanced duration of action
CN104829707B (zh) *	2015-05-06	2017-12-19	广东省生物资源应用研究所	一条cd环和e螺旋区突变的瘦素活性肽及其编码基因和应用
CN110183530A (zh) *	2019-06-21	2019-08-30	深圳市亚辉龙生物科技股份有限公司	瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6309853B1 (en) *	1994-08-17	2001-10-30	The Rockfeller University	Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
EP0836620A1 (en) *	1995-01-31	1998-04-22	Eli Lilly And Company	Anti-obesity proteins
US5552523A (en) *	1995-01-31	1996-09-03	Eli Lilly And Company	Anti-obesity proteins
AU4766596A (en) *	1995-01-31	1996-08-21	Eli Lilly And Company	Ob gene product antibodies
AU5539596A (en) *	1995-04-06	1996-10-23	Amylin Pharmaceuticals, Inc.	Anti-obesity agents
GB9509164D0 (en) *	1995-05-05	1995-06-28	Smithkline Beecham Plc	Novel compounds

1997
- 1997-06-04 JP JP10500240A patent/JP2000512137A/ja active Pending
- 1997-06-04 CN CN97195311A patent/CN1221426A/zh active Pending
- 1997-06-04 AR ARP970102432A patent/AR008765A1/es unknown
- 1997-06-04 BR BR9709529A patent/BR9709529A/pt not_active Application Discontinuation
- 1997-06-04 TR TR1998/02534T patent/TR199802534T2/xx unknown
- 1997-06-04 AU AU33372/97A patent/AU3337297A/en not_active Abandoned
- 1997-06-04 CZ CZ983978A patent/CZ397898A3/cs unknown
- 1997-06-04 KR KR1019980709976A patent/KR20000016402A/ko not_active Application Discontinuation
- 1997-06-04 NZ NZ332879A patent/NZ332879A/xx not_active IP Right Cessation
- 1997-06-04 EP EP97929156A patent/EP0912609A2/en not_active Withdrawn
- 1997-06-04 PL PL97330361A patent/PL330361A1/xx unknown
- 1997-06-04 CA CA002257240A patent/CA2257240A1/en not_active Abandoned
- 1997-06-04 IL IL12715397A patent/IL127153A0/xx unknown
- 1997-06-04 WO PCT/EP1997/002968 patent/WO1997046585A2/en not_active Application Discontinuation
1998
- 1998-12-04 NO NO985683A patent/NO985683L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO985683D0 (no)	1998-12-04
CZ397898A3 (cs)	1999-04-14
EP0912609A2 (en)	1999-05-06
TR199802534T2 (xx)	1999-03-22
JP2000512137A (ja)	2000-09-19
WO1997046585A3 (en)	1998-04-23
PL330361A1 (en)	1999-05-10
AR008765A1 (es)	2000-02-23
BR9709529A (pt)	1999-08-10
CN1221426A (zh)	1999-06-30
AU3337297A (en)	1998-01-05
NZ332879A (en)	2000-09-29
WO1997046585A2 (en)	1997-12-11
CA2257240A1 (en)	1997-12-11
KR20000016402A (ko)	2000-03-25
NO985683L (no)	1998-12-04

Publication	Publication Date	Title
IL127153A0 (en)	1999-09-22	Fragments of leptin (ob protein)
HUP9904239A3 (en)	2001-06-28	High level expression of proteins
AU5721798A (en)	1998-07-31	Human mage-like protein
AU5081298A (en)	1998-05-11	Surgical method and composition therefor
IL130396A0 (en)	2000-06-01	OB fusion protein compositions and methods
ZA964733B (en)	1997-01-07	Ob protein compositions and methods
AU4922497A (en)	1998-07-02	Interleukin-18-receptor proteins
AU2548097A (en)	1997-10-17	Formulations of ob protein
AU5796298A (en)	1998-07-03	Secreted human proteins
ZA9710338B (en)	1999-05-17	Proteins
AU4480697A (en)	1998-04-02	Human nm23-like protein
AU4750097A (en)	1998-05-11	Human reg i-gamma protein
AU5427398A (en)	1998-05-29	Cytoperfusion of tissue specimens
AU3451397A (en)	1998-02-02	Modified protein g and fragments thereof
AU1538497A (en)	1997-08-28	Anti-gp46 antibodies and fragments thereof and their use
AU2541397A (en)	1997-10-10	Tissue remodeling proteins
AU2245597A (en)	1997-08-20	Cross-linked polypeptide fragments of beta-galactosidase
AU1705197A (en)	1997-08-11	Obesity protein formulations
AU2111997A (en)	1997-08-20	Assays using cross-linked polypeptide fragments of beta-galactosidase
AU6883398A (en)	1998-10-22	Methods of treating bone loss
AU2243997A (en)	1997-08-11	Obesity protein formulations
AU1747297A (en)	1997-08-11	Obesity protein formulations
AU8747098A (en)	1999-03-16	Human galectin-9-like proteins and cdnas encoding these proteins
AU4744997A (en)	1998-04-24	Novel human phospholemman-like protein
AU4582597A (en)	1998-05-11	Therapeutic proteins