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IL125839A0 - Uses of gdnf and gdnf receptor - Google Patents

Uses of gdnf and gdnf receptor

Info

Publication number
IL125839A0
IL125839A0 IL12583997A IL12583997A IL125839A0 IL 125839 A0 IL125839 A0 IL 125839A0 IL 12583997 A IL12583997 A IL 12583997A IL 12583997 A IL12583997 A IL 12583997A IL 125839 A0 IL125839 A0 IL 125839A0
Authority
IL
Israel
Prior art keywords
gdnfrα
gdnf
methods
receptor
antibodies
Prior art date
Application number
IL12583997A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL125839A0 publication Critical patent/IL125839A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL12583997A 1996-03-14 1997-03-13 Uses of gdnf and gdnf receptor IL125839A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61590296A 1996-03-14 1996-03-14
US61823696A 1996-03-14 1996-03-14
PCT/US1997/004363 WO1997033912A2 (en) 1996-03-14 1997-03-13 Uses of gdnf and gdnf receptor

Publications (1)

Publication Number Publication Date
IL125839A0 true IL125839A0 (en) 1999-04-11

Family

ID=27087630

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12583997A IL125839A0 (en) 1996-03-14 1997-03-13 Uses of gdnf and gdnf receptor

Country Status (12)

Country Link
US (4) US6504007B1 (xx)
EP (1) EP0888385B1 (xx)
JP (1) JP4301347B2 (xx)
AT (1) ATE247667T1 (xx)
AU (1) AU719482B2 (xx)
CA (1) CA2246768C (xx)
DE (1) DE69724241T2 (xx)
DK (1) DK0888385T3 (xx)
ES (1) ES2206695T3 (xx)
IL (1) IL125839A0 (xx)
PT (1) PT888385E (xx)
WO (1) WO1997033912A2 (xx)

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US6696259B1 (en) * 1995-11-13 2004-02-24 Licentia Ltd. Assays using glial cell line-derived neurotrophic factor receptors
PT888385E (pt) 1996-03-14 2004-01-30 Genentech Inc Utilizacoes de gdnf e de receptores de gdnf
US6677135B1 (en) 1996-05-08 2004-01-13 Biogen, Inc. Ret ligand (RetL) for stimulating neutral and renal growth
IL126918A (en) * 1996-05-08 2007-06-03 Biogen Idec Inc Ret ligand (retl) for stimulating neural and renal growth
US20020068361A1 (en) * 1997-04-08 2002-06-06 Douglas Clary Methods of evaluating specific cellular functions of receptor protein tyrosine kinases in a ligand independent manner
NZ506748A (en) 1998-03-23 2002-10-25 Genentech Inc Nucleic acids encoding a GFR alpha 3 polypeptide; host cell and vectors for production of the GRF alpha 3 protein and an assay for detecting GRFalpha 3 production
US7026138B1 (en) 1998-03-23 2006-04-11 Genentech, Inc. Polynucleotides encoding GFRα3
DE19816186A1 (de) * 1998-04-14 1999-10-21 Univ Muenchen L Maximilians GDNF-kodierende DNA, Teile davon und GDNF-Varianten
US8197430B1 (en) 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
US6620382B1 (en) 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers
AU2354600A (en) * 1998-12-09 2000-06-26 Amgen, Inc. Grnf4 a neurotrophic factor
GB9915200D0 (en) 1999-06-29 1999-09-01 Janssen Pharmaceutica Nv Neurotrophic factor receptor
WO2004062619A2 (en) * 2003-01-13 2004-07-29 Macrogenics, Inc. SOLUBLE FcϜR FUSION PROTEINS AND METHODS OF USE THEREOF
US7480382B2 (en) * 2003-09-30 2009-01-20 Microsoft Corporation Image file container
JP4746048B2 (ja) * 2005-03-11 2011-08-10 オンコセラピー・サイエンス株式会社 抗ｇｆｒａ１抗体のエフェクター機能を用いて細胞を障害する方法
US8288354B2 (en) 2005-12-28 2012-10-16 The Scripps Research Institute Natural antisense and non-coding RNA transcripts as drug targets
US7863295B2 (en) * 2008-02-12 2011-01-04 Children's Medical Center Corporation Treatments for neuropathy
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CN107338251A (zh) 2008-12-04 2017-11-10 库尔纳公司 通过抑制肿瘤抑制基因的天然反义转录物治疗肿瘤抑制基因相关性疾病
CA2746003C (en) * 2008-12-04 2020-03-31 Opko Curna, Llc Treatment of vascular endothelial growth factor (vegf) related diseases by inhibition of natural antisense transcript to vegf
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CN102439149B (zh) * 2009-02-12 2018-01-02 库尔纳公司 通过抑制针对胶质细胞衍生神经营养因子(gdnf)的天然反义转录物来治疗gdnf相关的疾病
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CA2765509C (en) 2009-06-16 2021-08-17 Joseph Collard Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
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KR101807323B1 (ko) 2009-06-24 2017-12-08 큐알엔에이, 인크. Ｔｎｆｒ2에 대한 천연 안티센스 전사체의 억제에 의한 종양 괴사 인자 수용체 2(ｔｎｆｒ2) 관련된 질환의 치료
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CN103180445B (zh) 2010-10-22 2018-02-16 库尔纳公司 通过抑制α‑L‑艾杜糖醛酸酶(IDUA)的天然反义转录物而治疗IDUA相关疾病
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Also Published As

Publication number Publication date
WO1997033912A2 (en) 1997-09-18
US20100313283A1 (en) 2010-12-09
JP2000511402A (ja) 2000-09-05
EP0888385B1 (en) 2003-08-20
WO1997033912A3 (en) 1998-02-05
US6504007B1 (en) 2003-01-07
DE69724241D1 (de) 2003-09-25
US20060142196A1 (en) 2006-06-29
DK0888385T3 (da) 2003-12-15
ES2206695T3 (es) 2004-05-16
AU719482B2 (en) 2000-05-11
US7105484B2 (en) 2006-09-12
CA2246768A1 (en) 1997-09-18
PT888385E (pt) 2004-01-30
EP0888385A2 (en) 1999-01-07
AU2217297A (en) 1997-10-01
DE69724241T2 (de) 2004-06-09
ATE247667T1 (de) 2003-09-15
US20030022284A1 (en) 2003-01-30
CA2246768C (en) 2013-12-31
US7691606B2 (en) 2010-04-06
JP4301347B2 (ja) 2009-07-22

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