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IL113339A - Mutant viral nucleotide sequences - Google Patents

Mutant viral nucleotide sequences

Info

Publication number
IL113339A
IL113339A IL113339A IL11333989A IL113339A IL 113339 A IL113339 A IL 113339A IL 113339 A IL113339 A IL 113339A IL 11333989 A IL11333989 A IL 11333989A IL 113339 A IL113339 A IL 113339A
Authority
IL
Israel
Prior art keywords
gene
ribonucleotide reductase
mutation
large subunit
nucleotide sequences
Prior art date
Application number
IL113339A
Other languages
English (en)
Original Assignee
Rhone Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888821441A external-priority patent/GB8821441D0/en
Application filed by Rhone Merieux filed Critical Rhone Merieux
Publication of IL113339A publication Critical patent/IL113339A/xx

Links

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    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/255Marek's disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0093Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • CCHEMISTRY; METALLURGY
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211Thymidine kinase (2.7.1.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
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    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2710/00011Details
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16041Use of virus, viral particle or viral elements as a vector
    • C12N2710/16043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Biochemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
IL113339A 1988-09-13 1989-09-13 Mutant viral nucleotide sequences IL113339A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888821441A GB8821441D0 (en) 1988-09-13 1988-09-13 Viral vectors
IL9162789A IL91627A (en) 1988-09-13 1989-09-13 Viral nucleotide segments
US08/654,931 US5744143A (en) 1988-09-13 1996-05-29 Viral vaccines

Publications (1)

Publication Number Publication Date
IL113339A true IL113339A (en) 1997-03-18

Family

ID=26294384

Family Applications (3)

Application Number Title Priority Date Filing Date
IL113339A IL113339A (en) 1988-09-13 1989-09-13 Mutant viral nucleotide sequences
IL9162789A IL91627A (en) 1988-09-13 1989-09-13 Viral nucleotide segments
IL11333995A IL113339A0 (en) 1988-09-13 1995-04-12 Mutant viral nucleotide sequences

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL9162789A IL91627A (en) 1988-09-13 1989-09-13 Viral nucleotide segments
IL11333995A IL113339A0 (en) 1988-09-13 1995-04-12 Mutant viral nucleotide sequences

Country Status (6)

Country Link
US (3) US5744143A (fr)
EP (3) EP0434747B1 (fr)
JP (2) JP3339854B2 (fr)
AU (2) AU629248B2 (fr)
IL (3) IL113339A (fr)
WO (2) WO1990002802A2 (fr)

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US5965138A (en) * 1985-09-06 1999-10-12 Syntro Corporation Recombinant chimeric virus and uses thereof
IL113339A (en) * 1988-09-13 1997-03-18 Rhone Merieux Mutant viral nucleotide sequences
FR2659349B1 (fr) * 1990-03-12 1993-12-24 Rhone Merieux Virus herpes recombinants notamment pour la realisation de vaccins, leur procede de preparation, les plasmides realises au cours de ce procede et les vaccins obtenus.
US6087127A (en) * 1990-08-24 2000-07-11 Board Of Trustees Operating Michigan State University Marek's disease herpesvirus DNA segment encoding glycoproteins, gD, gI and gE
WO1992003554A1 (fr) * 1990-08-24 1992-03-05 Arthur Webster Pty. Ltd. Vaccin contre le virus de la laryngotracheite infectieuse
FR2666589B1 (fr) * 1990-09-07 1994-08-05 Rhone Merieux Nouveaux virus herpes recombinants, vaccin a base de ces recombinants, leur procede de preparation, genes, vecteurs et plasmides utilises dans ce procede.
NL9002008A (nl) 1990-09-12 1992-04-01 Stichting Centr Diergeneeskund Recombinant dna en rna en daarvan afgeleide produkten.
EP0486106A3 (en) * 1990-11-16 1992-12-23 Akzo N.V. Marek's disease virus vaccine
US5759552A (en) * 1991-03-07 1998-06-02 Virogenetics Corporation Marek's disease virus recombinant poxvirus vaccine
US5369025A (en) * 1991-06-28 1994-11-29 The United States Of America As Represented By The Secretary Of Agriculture Recombinant fowlpox vaccine for protection against Marek's disease
AU657144B2 (en) * 1991-07-09 1995-03-02 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Recombinant Marek's disease virus, process for preparing the same and vaccine containing the same
US5223408A (en) * 1991-07-11 1993-06-29 Genentech, Inc. Method for making variant secreted proteins with altered properties
US5443831A (en) * 1991-10-29 1995-08-22 University Of Delaware Gene encoding glycoprotein B of Infectious Laryngotracheitis Virus
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US5643578A (en) 1992-03-23 1997-07-01 University Of Massachusetts Medical Center Immunization by inoculation of DNA transcription unit
US6165993A (en) * 1992-03-23 2000-12-26 University Of Massachusetts Medical Center DNA vaccines against rotavirus infections
US5620896A (en) * 1992-03-23 1997-04-15 University Of Massachusetts Medical Center DNA vaccines against rotavirus infections
US5853733A (en) * 1993-02-26 1998-12-29 Syntro Corporation Recombinant herpesvirus of turkeys and uses thereof
GB9213882D0 (en) * 1992-06-30 1992-08-12 Univ Court Of The University O Live modified equine herpesvirus-4 vaccine
AU7838694A (en) * 1993-09-24 1995-04-10 Syntro Corporation Recombinant infectious laryngotracheitis virus and uses thereof
US6984728B2 (en) 1993-09-24 2006-01-10 Schering Corporation Recombinant infectious laryngotracheitis virus and uses thereof
EP0750670A1 (fr) * 1994-02-07 1997-01-02 Cornell Research Foundation, Inc. Compositions utiles pour traiter la maladie de marek
FR2719056B1 (fr) * 1994-04-20 1996-09-06 Rhone Merieux Herpesvirus transformés pour exprimer gD in vitro.
WO1996000791A1 (fr) * 1994-06-30 1996-01-11 The Board Of Trustees Of The University Of Illinois Virus de recombinaison de la laryngo-tracheite infectieuse et vaccin
FR2728794B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin recombinant aviaire a base de virus herpes aviaire, notamment contre la maladie de gumboro
FR2728795B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire
WO1996029396A1 (fr) * 1995-03-23 1996-09-26 Syntro Corporation Virus de la laryngotracheite infectieuse recombine et ses utilisations
JPH08322559A (ja) * 1995-06-02 1996-12-10 Chemo Sero Therapeut Res Inst gB遺伝子プロモーターを用いた組換えヘルペスウイルス
KR19990028766A (ko) * 1995-07-07 1999-04-15 나카노 가쓰히꼬 마렉 질환 바이러스 유전자 및 마렉 질환 예방용 백신에서그의 용도
FR2750866B1 (fr) * 1996-06-27 1998-11-27 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire
FR2757061B1 (fr) * 1996-12-16 1999-03-26 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire
CN100518827C (zh) * 2000-10-30 2009-07-29 欧罗赛铁克股份有限公司 控释氢可酮制剂
ES2344594T3 (es) 2001-01-31 2010-09-01 Mayo Foundation For Medical Education And Research Deteccion del virus del herpes simplex.
US7037506B2 (en) * 2002-03-08 2006-05-02 Schweltzer Chemical Corporation Ltd. Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry
US7029681B2 (en) * 2002-03-08 2006-04-18 Schweitzer Chemical Corporation Multiple and multivalent DNA vaccines in ovo
US8754031B2 (en) 2004-03-08 2014-06-17 Oncolix, Inc. Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway
CA2568642A1 (fr) 2004-05-27 2005-12-15 Centocor, Inc. Antigene specifique de la prostate du singe cynomolgus
US20050276758A1 (en) * 2004-06-15 2005-12-15 Marshall Deborah J Method for screening agents against human prostate disease
WO2007022151A2 (fr) 2005-08-15 2007-02-22 Vaxin, Inc. Immunisation d'oiseaux par administration de vaccins a vecteurs non repliquants
CN100460509C (zh) * 2007-01-04 2009-02-11 首都医科大学 旋毛虫副肌球蛋白基因及其应用
TW201109913A (en) * 2009-09-02 2011-03-16 Inventec Corp Main system board error-detecting system and its pluggable error-detecting board
JP2023506919A (ja) 2019-12-20 2023-02-20 インターベット インターナショナル ベー. フェー. 多価hvtベクターワクチン
EP4267179A1 (fr) 2020-12-24 2023-11-01 Intervet International B.V. Vaccin à vecteur hvt multivalent
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US5965138A (en) * 1985-09-06 1999-10-12 Syntro Corporation Recombinant chimeric virus and uses thereof
WO1987004463A1 (fr) * 1986-01-27 1987-07-30 Syntro Corporation Virus herpetiques attenues, virus herpetiques comprenant de l'adn etranger contenant une sequence d'acide amine et vaccin les contenant
JPH02502693A (ja) * 1987-03-19 1990-08-30 サイナーゲン,インコーポレーテッド 外来dna発現産物の家禽類への導入のためのウイルスベクター系およびその作製方法
US4996152A (en) * 1987-12-04 1991-02-26 The United States Of America, As Represented By The Secretary Of Agriculture Avian herpesvirus amplicon as a eucaryotic expression vector
DE68926712T2 (de) * 1988-05-02 1997-04-17 The United States Of America, Represented By The Secretary, U.S. Department Of Commerce, Springfield, Va. Gen zum kodieren eines antigens gegen menschlichen malaria impfstoff
IL113339A (en) * 1988-09-13 1997-03-18 Rhone Merieux Mutant viral nucleotide sequences
US5558860A (en) * 1988-09-13 1996-09-24 Rhone Merieux Viral vaccines
EP0431668B1 (fr) * 1989-12-04 1995-02-15 Akzo Nobel N.V. Virus herpès de dinde recombinant et vaccins-vecteurs vivants dérivés de celui-ci

Also Published As

Publication number Publication date
EP0748631B1 (fr) 2006-02-08
EP0434747A1 (fr) 1991-07-03
WO1990002802A3 (fr) 1990-05-17
US5958425A (en) 1999-09-28
AU629248B2 (en) 1992-10-01
EP0748631A3 (fr) 2000-02-23
IL113339A0 (en) 1995-07-31
JPH04501658A (ja) 1992-03-26
IL91627A (en) 1995-08-31
EP0434747B1 (fr) 1999-05-19
AU633272B2 (en) 1993-01-28
WO1990002802A2 (fr) 1990-03-22
EP0434721B1 (fr) 2000-03-15
EP0434721A1 (fr) 1991-07-03
EP0748631A2 (fr) 1996-12-18
JP3292371B2 (ja) 2002-06-17
US5744143A (en) 1998-04-28
AU4214289A (en) 1990-04-02
WO1990002803A3 (fr) 1990-05-31
JP3339854B2 (ja) 2002-10-28
US6100088A (en) 2000-08-08
AU4325089A (en) 1990-04-02
JPH04502852A (ja) 1992-05-28
WO1990002803A2 (fr) 1990-03-22

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