IE41590L - Cephalosporin compounds - Google Patents
Cephalosporin compoundsInfo
- Publication number
- IE41590L IE41590L IE751693A IE169375A IE41590L IE 41590 L IE41590 L IE 41590L IE 751693 A IE751693 A IE 751693A IE 169375 A IE169375 A IE 169375A IE 41590 L IE41590 L IE 41590L
- Authority
- IE
- Ireland
- Prior art keywords
- image
- formula
- reaction
- hand
- cephalosporin compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel cephalosporins of the general formula <IMAGE> are obtained by reaction of a 3-acetoxymethylcephalosporin of the formula <IMAGE> with a triazinylthio derivative of the formula <IMAGE> The substituents are defined in Claim 1. If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desired, the compounds obtained according to the invention are acylated by the known processes. The reaction is preferably carried out in polar solvents, e.g. water. These novel cephalosporins are to be used on the one hand as medicines having antibiotic activity or on the other hand as intermediates in the preparation of antibiotics.
[GB1521073A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49414874A | 1974-08-02 | 1974-08-02 | |
| US58392475A | 1975-06-10 | 1975-06-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41590L true IE41590L (en) | 1976-02-02 |
| IE41590B1 IE41590B1 (en) | 1980-02-13 |
Family
ID=27051316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1693/75A IE41590B1 (en) | 1974-08-02 | 1975-07-29 | Novel cephalosporin compounds |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS6123195B2 (en) |
| AR (1) | AR210998A1 (en) |
| AT (1) | AT347580B (en) |
| BG (1) | BG26395A3 (en) |
| CA (1) | CA1100129A (en) |
| CH (1) | CH616683A5 (en) |
| CS (1) | CS189716B2 (en) |
| DD (1) | DD121114A5 (en) |
| DE (1) | DE2534071A1 (en) |
| DK (1) | DK343275A (en) |
| FR (1) | FR2280381A1 (en) |
| GB (1) | GB1521073A (en) |
| HU (1) | HU174130B (en) |
| IE (1) | IE41590B1 (en) |
| IL (1) | IL47802A (en) |
| NL (1) | NL7509053A (en) |
| PH (1) | PH16078A (en) |
| PL (1) | PL95607B1 (en) |
| RO (1) | RO72980A (en) |
| SE (1) | SE426830B (en) |
| SU (1) | SU755200A3 (en) |
| YU (1) | YU197075A (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4348518A (en) | 1974-05-05 | 1982-09-07 | Hoffmann-La Roche Inc. | Cephalosporins |
| JPS50141233U (en) * | 1974-05-08 | 1975-11-20 | ||
| CA1083141A (en) * | 1977-03-07 | 1980-08-05 | Lowell D. Hatfield | Cephalosporin displacement reaction |
| GB1599232A (en) * | 1977-06-03 | 1981-09-30 | Hoffmann La Roche | 7-(2-oximinoacetamido)-cephalosporin derivatives |
| US4200745A (en) * | 1977-12-20 | 1980-04-29 | Eli Lilly And Company | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins |
| MC1259A1 (en) * | 1978-05-30 | 1980-01-14 | Hoffmann La Roche | ACYL DERIVATIVES |
| DK225179A (en) | 1978-06-22 | 1979-12-23 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR PREPARING CEPHALOSPORINE DERIVATIVES |
| FI782683A (en) * | 1978-07-19 | 1980-01-20 | Hoffmann La Roche | KEFALOSPORINESTRAR OCH -ESTRAR |
| NL8100089A (en) | 1980-01-17 | 1981-08-17 | Rhone Poulenc Ind | NEW THIOLS AND THEIR PREPARATION. |
| FR2474030A1 (en) * | 1980-01-17 | 1981-07-24 | Rhone Poulenc Ind | 2-Mercapto-1,2,4-triazine, 1,3,4-triazole or tetrazole derivs. - useful as intermediates for antibacterial cephalosporin(s) |
| FR2494278A1 (en) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | NEW DERIVATIVES OF CEPHALOSPORIN, THEIR PREPARATIONS AND THE MEDICINAL PRODUCTS CONTAINING THEM |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116436B1 (en) * | 1971-05-31 | 1976-05-24 |
-
1975
- 1975-07-24 CA CA232,136A patent/CA1100129A/en not_active Expired
- 1975-07-25 RO RO7593489A patent/RO72980A/en unknown
- 1975-07-25 CS CS755262A patent/CS189716B2/en unknown
- 1975-07-25 IL IL47802A patent/IL47802A/en unknown
- 1975-07-25 FR FR7523346A patent/FR2280381A1/en active Granted
- 1975-07-28 SE SE7508570A patent/SE426830B/en not_active IP Right Cessation
- 1975-07-29 NL NL7509053A patent/NL7509053A/en not_active Application Discontinuation
- 1975-07-29 JP JP50092486A patent/JPS6123195B2/ja not_active Expired
- 1975-07-29 DK DK343275A patent/DK343275A/en not_active Application Discontinuation
- 1975-07-29 SU SU752163060A patent/SU755200A3/en active
- 1975-07-29 GB GB31598/75A patent/GB1521073A/en not_active Expired
- 1975-07-29 IE IE1693/75A patent/IE41590B1/en unknown
- 1975-07-30 DE DE19752534071 patent/DE2534071A1/en not_active Withdrawn
- 1975-07-31 CH CH1005975A patent/CH616683A5/en not_active IP Right Cessation
- 1975-07-31 AT AT594075A patent/AT347580B/en active
- 1975-07-31 AR AR259862A patent/AR210998A1/en active
- 1975-08-01 DD DD187628A patent/DD121114A5/xx unknown
- 1975-08-01 YU YU01970/75A patent/YU197075A/en unknown
- 1975-08-01 HU HU75EI637A patent/HU174130B/en unknown
- 1975-08-01 PL PL1975182474A patent/PL95607B1/en unknown
- 1975-08-02 BG BG030722A patent/BG26395A3/en unknown
-
1977
- 1977-08-26 PH PH20172A patent/PH16078A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR210998A1 (en) | 1977-10-14 |
| SE426830B (en) | 1983-02-14 |
| CS189716B2 (en) | 1979-04-30 |
| SU755200A3 (en) | 1980-08-07 |
| CA1100129A (en) | 1981-04-28 |
| FR2280381A1 (en) | 1976-02-27 |
| CH616683A5 (en) | 1980-04-15 |
| FR2280381B1 (en) | 1979-08-10 |
| IL47802A (en) | 1980-05-30 |
| SE7508570L (en) | 1976-02-03 |
| IE41590B1 (en) | 1980-02-13 |
| RO72980A (en) | 1981-08-30 |
| JPS6123195B2 (en) | 1986-06-04 |
| ATA594075A (en) | 1976-11-15 |
| HU174130B (en) | 1979-11-28 |
| DD121114A5 (en) | 1976-07-12 |
| JPS5139693A (en) | 1976-04-02 |
| YU197075A (en) | 1982-05-31 |
| PH16078A (en) | 1983-06-20 |
| DK343275A (en) | 1976-02-03 |
| NL7509053A (en) | 1976-02-04 |
| BG26395A3 (en) | 1979-03-15 |
| PL95607B1 (en) | 1977-10-31 |
| GB1521073A (en) | 1978-08-09 |
| DE2534071A1 (en) | 1976-02-12 |
| AT347580B (en) | 1979-01-10 |
| IL47802A0 (en) | 1975-10-15 |
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