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ID17275A - N-[4-(heteroarilmetil)fenil]-heteroarilamina - Google Patents

N-[4-(heteroarilmetil)fenil]-heteroarilamina

Info

Publication number
ID17275A
ID17275A IDP972217A ID972217A ID17275A ID 17275 A ID17275 A ID 17275A ID P972217 A IDP972217 A ID P972217A ID 972217 A ID972217 A ID 972217A ID 17275 A ID17275 A ID 17275A
Authority
ID
Indonesia
Prior art keywords
heteroarilmetil
heteroarilamina
fenil
Prior art date
Application number
IDP972217A
Other languages
English (en)
Inventor
Marc Gaston Venet
Dominique Jean Pierre Mabire
Jean Fernand Armand Lacrampe
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ID17275A publication Critical patent/ID17275A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDP972217A 1996-06-27 1997-06-26 N-[4-(heteroarilmetil)fenil]-heteroarilamina ID17275A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201781 1996-06-27

Publications (1)

Publication Number Publication Date
ID17275A true ID17275A (id) 1997-12-18

Family

ID=8224119

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972217A ID17275A (id) 1996-06-27 1997-06-26 N-[4-(heteroarilmetil)fenil]-heteroarilamina

Country Status (33)

Country Link
US (5) US6124330A (id)
EP (1) EP0907650B1 (id)
JP (1) JP3404749B2 (id)
KR (1) KR100365312B1 (id)
CN (1) CN1102593C (id)
AR (1) AR007626A1 (id)
AT (1) ATE229019T1 (id)
AU (1) AU711575B2 (id)
BG (1) BG63545B1 (id)
BR (1) BR9710002A (id)
CA (1) CA2258165C (id)
CZ (1) CZ297769B6 (id)
DE (1) DE69717627T2 (id)
DK (1) DK0907650T3 (id)
EE (1) EE03688B1 (id)
ES (1) ES2188957T3 (id)
HK (1) HK1018458A1 (id)
HU (1) HU223093B1 (id)
ID (1) ID17275A (id)
IL (1) IL127740A (id)
MY (1) MY116917A (id)
NO (1) NO312102B1 (id)
NZ (1) NZ333382A (id)
PL (1) PL201704B1 (id)
PT (1) PT907650E (id)
RU (1) RU2190611C2 (id)
SI (1) SI0907650T1 (id)
SK (1) SK282769B6 (id)
TR (1) TR199802709T2 (id)
TW (1) TW490464B (id)
UA (1) UA53649C2 (id)
WO (1) WO1997049704A1 (id)
ZA (1) ZA975698B (id)

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UA53649C2 (uk) * 1996-06-27 2003-02-17 Янссен Фармацевтика Н.В. N-[4-(гетероарилметил)феніл]гетероариламіни, композиція на їх основі та спосіб її одержання, спосіб одержання сполук (варіанти)
US6319939B1 (en) 1997-12-11 2001-11-20 Janssen Pharmaceutica N.V. Retinoic acid mimetic anlides
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
DE19951701A1 (de) 1999-10-27 2001-05-03 Aventis Pharma Gmbh Verwendung von 2-Imidazolyl-substituierten Carbinolen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten
AU2003223672A1 (en) * 2002-04-17 2003-11-03 Tyco Healthcare Group Lp Method and apparatus for anastomosis including an expandable anchor
EP1558586B1 (en) 2002-10-30 2011-03-30 Merck Sharp & Dohme Corp. Inhibitors of akt activity
US7638530B2 (en) 2003-04-24 2009-12-29 Merck & Co., Inc. Inhibitors of Akt activity
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
JP5129957B2 (ja) * 2003-07-03 2013-01-30 ミリアド ジェネティクス， インコーポレイテッド カスパーゼの活性化因子およびアポトーシスの誘発因子としての４−アリールアミノ−キナゾリン
DE10337942A1 (de) * 2003-08-18 2005-03-17 Merck Patent Gmbh Aminobenzimidazolderivate
BRPI0516083A (pt) 2004-09-24 2008-08-19 Allergan Sales Inc 4-(fenilmetil e 4-fenilmetil substituìdo)-imidazol-2-tionas que atuam como agonistas alfa2 adrenérgicos
CA2581828A1 (en) * 2004-09-24 2006-04-06 Allergan, Inc. 4-(heteroaryl-methyl and substituted heteroaryl-methyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists
CN101052638B (zh) * 2004-09-24 2011-01-19 阿勒根公司 作为α2肾上腺素能激动剂的4-（缩合环甲基）-咪唑-2-硫酮
KR101202066B1 (ko) * 2004-09-28 2012-11-15 알러간, 인코포레이티드 특이적인 또는 선택적인 알파2 아드레날린성아고니스트로서 작용하는 비치환된 및 치환된4-벤질-1,3-디히드로-이미다졸-2-티온 및 이를 사용하는방법
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US7547782B2 (en) * 2005-09-30 2009-06-16 Bristol-Myers Squibb Company Met kinase inhibitors
CA2637590C (en) * 2006-01-17 2014-03-18 Barrier Therapeutics, Inc. Treatment of inflammatory disorders with triazole compounds
US8188124B2 (en) 2006-10-17 2012-05-29 Stiefel Laboratories, Inc. Talarazole metabolites
CN101827841B (zh) * 2007-10-18 2012-11-28 多派股份公司 (r)-4-(杂芳基)苯乙基衍生物及其药物组合物
GB0811091D0 (en) * 2008-06-17 2008-07-23 Cancer Rec Tech Ltd CYP26 Inhibitors
US8513291B2 (en) 2010-06-01 2013-08-20 Angion Biomedica Corp. Cytochrome P450 inhibitors and uses thereof
US10414760B2 (en) 2016-11-29 2019-09-17 Angion Biomedica Corp. Cytochrome P450 inhibitors and uses thereof
KR101108577B1 (ko) * 2010-07-28 2012-01-30 국제엘렉트릭코리아 주식회사 테이프 히터
HUE037860T2 (hu) 2010-11-19 2018-09-28 Ligand Pharm Inc Heterociklusos aminok és alkalmazásuk
US9248120B2 (en) 2011-08-23 2016-02-02 The Board Of Trustees Of The Leland Stanford Junior University Reversing intestinal inflammation by inhibiting retinoic acid metabolism
EP3180335B1 (en) 2014-08-11 2021-05-05 Angion Biomedica Corporation Cytochrome p450 inhibitors and uses thereof
EP3240778A4 (en) 2014-12-31 2018-07-11 Angion Biomedica Corp. Methods and agents for treating disease
US10807983B2 (en) 2015-03-16 2020-10-20 Ligand Pharmaceuticals, Inc. Imidazo-fused heterocycles and uses thereof
CN106632051A (zh) * 2016-12-15 2017-05-10 青岛辰达生物科技有限公司 一种盐酸右美托咪定中间体的合成方法
CN106588780A (zh) * 2016-12-15 2017-04-26 青岛辰达生物科技有限公司 一种盐酸右美托咪定中间体的制备工艺
CN106588779A (zh) * 2016-12-15 2017-04-26 青岛辰达生物科技有限公司 一种合成盐酸右美托咪定中间体的方法
KR20210055340A (ko) 2019-11-07 2021-05-17 정화종 화물 커버
CN115462347B (zh) * 2021-08-13 2024-07-16 广州市妇女儿童医疗中心 视黄酸代谢通路在先天性巨结肠疾病中的应用

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NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
US5202323A (en) 1990-04-25 1993-04-13 Nissan Chemical Industries Ltd. 5-arylmethylamino-6-oxy-substituted 3(2h)-pyridazinones
TW321649B (id) 1994-11-12 1997-12-01 Zeneca Ltd
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US6184225B1 (en) 1996-02-13 2001-02-06 Zeneca Limited Quinazoline derivatives as VEGF inhibitors
US5731342A (en) * 1996-02-22 1998-03-24 Eli Lilly And Company Benzothiophenes, formulations containing same, and methods
UA53649C2 (uk) * 1996-06-27 2003-02-17 Янссен Фармацевтика Н.В. N-[4-(гетероарилметил)феніл]гетероариламіни, композиція на їх основі та спосіб її одержання, спосіб одержання сполук (варіанти)

Also Published As

Publication number Publication date
IL127740A (en) 2001-09-13
NO986017D0 (no) 1998-12-21
BG103013A (en) 1999-09-30
US20030176419A1 (en) 2003-09-18
BG63545B1 (bg) 2002-04-30
CZ423198A3 (cs) 1999-05-12
WO1997049704A1 (en) 1997-12-31
TW490464B (en) 2002-06-11
CN1102593C (zh) 2003-03-05
HK1018458A1 (en) 1999-12-24
EE03688B1 (et) 2002-04-15
EE9800437A (et) 1999-06-15
HU223093B1 (hu) 2004-03-29
EP0907650A1 (en) 1999-04-14
JP2000503670A (ja) 2000-03-28
KR20000016196A (ko) 2000-03-25
JP3404749B2 (ja) 2003-05-12
IL127740A0 (en) 1999-10-28
SK178198A3 (en) 2000-05-16
DE69717627T2 (de) 2003-09-18
US6486187B1 (en) 2002-11-26
HUP9902138A2 (hu) 1999-10-28
BR9710002A (pt) 1999-08-10
PL201704B1 (pl) 2009-04-30
CZ297769B6 (cs) 2007-03-28
NO312102B1 (no) 2002-03-18
SI0907650T1 (en) 2003-06-30
PT907650E (pt) 2003-04-30
CN1223654A (zh) 1999-07-21
MY116917A (en) 2004-04-30
UA53649C2 (uk) 2003-02-17
SK282769B6 (sk) 2002-12-03
ZA975698B (en) 1999-01-20
CA2258165A1 (en) 1997-12-31
US20050113378A1 (en) 2005-05-26
AR007626A1 (es) 1999-11-10
AU3435697A (en) 1998-01-14
NO986017L (no) 1999-02-19
US7378433B2 (en) 2008-05-27
US6124330A (en) 2000-09-26
NZ333382A (en) 2000-05-26
US7205312B2 (en) 2007-04-17
ATE229019T1 (de) 2002-12-15
AU711575B2 (en) 1999-10-14
KR100365312B1 (ko) 2003-03-06
US6833375B2 (en) 2004-12-21
ES2188957T3 (es) 2003-07-01
RU2190611C2 (ru) 2002-10-10
DE69717627D1 (de) 2003-01-16
PL330816A1 (en) 1999-06-07
EP0907650B1 (en) 2002-12-04
HUP9902138A3 (en) 2001-10-29
DK0907650T3 (da) 2003-03-10
CA2258165C (en) 2009-03-03
TR199802709T2 (xx) 1999-02-22
US20070088062A1 (en) 2007-04-19

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