HUP9903698A2 - A pentoxifyllin és az I-es típusú interferonok kombinált alkalmazása a szklerózis multiplex kezelésére - Google Patents
A pentoxifyllin és az I-es típusú interferonok kombinált alkalmazása a szklerózis multiplex kezeléséreInfo
- Publication number
- HUP9903698A2 HUP9903698A2 HU9903698A HUP9903698A HUP9903698A2 HU P9903698 A2 HUP9903698 A2 HU P9903698A2 HU 9903698 A HU9903698 A HU 9903698A HU P9903698 A HUP9903698 A HU P9903698A HU P9903698 A2 HUP9903698 A2 HU P9903698A2
- Authority
- HU
- Hungary
- Prior art keywords
- multiple sclerosis
- pentoxifylline
- interferons
- type
- combination
- Prior art date
Links
- 102000002227 Interferon Type I Human genes 0.000 title abstract 2
- 108010014726 Interferon Type I Proteins 0.000 title abstract 2
- BYPFEZZEUUWMEJ-UHFFFAOYSA-N Pentoxifylline Chemical compound O=C1N(CCCCC(=O)C)C(=O)N(C)C2=C1N(C)C=N2 BYPFEZZEUUWMEJ-UHFFFAOYSA-N 0.000 title abstract 2
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 2
- 229960001476 pentoxifylline Drugs 0.000 title abstract 2
- 206010053395 Progressive multiple sclerosis Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány a heveny fellőbbanásős és a másődlagősan prőgrediálószklerózis műltiplex kőmbinált kezelésére vőnatkőzik. A kőmbináltkezelés I-es típűsú interferőnők szűbkűtán vagy intraműszkűlárisadagőlásával és a Pentőxifyllin egyidejű perőrális alkalmazásávaltörténik, mely űtóbbi adőtt esetben késleltetett hatású lehet. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19544768A DE19544768C1 (de) | 1995-11-30 | 1995-11-30 | Verwendung einer Kombination aus Pentoxifyllin mit Typ-I-Interferonen zur Behandlung der Multiplen Sklerose |
PCT/EP1996/004906 WO1997019686A1 (de) | 1995-11-30 | 1996-11-08 | Verwendung einer kombination aus pentoxifyllin mit typ i-interferonen zur behandlung der multiplen sklerose |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP9903698A2 true HUP9903698A2 (hu) | 2000-03-28 |
Family
ID=7778885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903698A HUP9903698A2 (hu) | 1995-11-30 | 1996-11-08 | A pentoxifyllin és az I-es típusú interferonok kombinált alkalmazása a szklerózis multiplex kezelésére |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0863759A1 (hu) |
JP (1) | JP2000501085A (hu) |
CA (1) | CA2238770A1 (hu) |
DE (1) | DE19544768C1 (hu) |
HU (1) | HUP9903698A2 (hu) |
NO (1) | NO982463L (hu) |
WO (1) | WO1997019686A1 (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPP823999A0 (en) * | 1999-01-20 | 1999-02-11 | University Of Queensland, The | A treatment |
WO2007041506A1 (en) * | 2005-10-03 | 2007-04-12 | Melior Discovery, Inc. | Purine formulations and methods for managing disorders |
US20090239886A1 (en) | 2008-02-29 | 2009-09-24 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
MX2012002704A (es) | 2009-09-02 | 2012-03-21 | Concert Pharmaceuticals Inc | Derivados de xantina sustituidos. |
WO2012031138A2 (en) | 2010-09-01 | 2012-03-08 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione |
US20140296263A1 (en) | 2011-07-19 | 2014-10-02 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
EP2836492B1 (en) | 2012-04-13 | 2018-03-14 | Concert Pharmaceuticals Inc. | Substituted xanthine derivatives |
WO2013159006A1 (en) | 2012-04-20 | 2013-10-24 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione |
US20170216296A1 (en) | 2014-04-18 | 2017-08-03 | Concert Pharmaceuticals, Inc. | Methods of treating hyperglycemia |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU538186B2 (en) * | 1980-03-07 | 1984-08-02 | Scotia Holdings Plc | Prostaglandin precursors |
US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
US5763446A (en) * | 1992-03-26 | 1998-06-09 | University Of Southern California | Use of pentoxifylline and other tumor necrosis factor blockers for the treatment of aids-associated optic neuropathy and other central nervous system diseases |
GB9218810D0 (en) * | 1992-09-04 | 1992-10-21 | Univ Birmingham | Antiviral pyrimidine nucleosides |
DE4343034C1 (de) * | 1993-12-16 | 1995-06-08 | Rentschler Arzneimittel | Verwendung von Pentoxifyllin zur Behandlung von Multipler Sklerose |
-
1995
- 1995-11-30 DE DE19544768A patent/DE19544768C1/de not_active Expired - Fee Related
-
1996
- 1996-11-08 HU HU9903698A patent/HUP9903698A2/hu unknown
- 1996-11-08 WO PCT/EP1996/004906 patent/WO1997019686A1/de not_active Application Discontinuation
- 1996-11-08 CA CA002238770A patent/CA2238770A1/en not_active Abandoned
- 1996-11-08 JP JP9520104A patent/JP2000501085A/ja active Pending
- 1996-11-08 EP EP96938998A patent/EP0863759A1/de not_active Withdrawn
-
1998
- 1998-05-29 NO NO982463A patent/NO982463L/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO982463D0 (no) | 1998-05-29 |
JP2000501085A (ja) | 2000-02-02 |
WO1997019686A1 (de) | 1997-06-05 |
CA2238770A1 (en) | 1997-06-05 |
DE19544768C1 (de) | 1997-07-10 |
EP0863759A1 (de) | 1998-09-16 |
NO982463L (no) | 1998-05-29 |
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