HUP0004070A2 - 5-[4-{2-[N-Metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxotiazolidint tartalmazó gyógyszerkészítmények - Google Patents

5-[4-{2-[N-Metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxotiazolidint tartalmazó gyógyszerkészítmények

Info

Publication number: HUP0004070A2
Authority: HU; Hungary
Prior art keywords: thiazolidine; dione; pyridyl; ethoxy; benzyl
Prior art date: 1997-06-05

Application number

HU0004070A

Other languages

English (en)

Inventor

Jeffrey Roger Granett

Jai Patel

Robin Price

Hamish Ross

Paul Nigel Wray

Original Assignee

Smithkline Beecham Corp.

Smithkline Beecham P.L.C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-05

Filing date

1998-06-02

Publication date

2002-02-28

1997-06-18 Priority claimed from GBGB9712851.6A external-priority patent/GB9712851D0/en

1998-06-02 Application filed by Smithkline Beecham Corp., Smithkline Beecham P.L.C. filed Critical Smithkline Beecham Corp.

2002-02-28 Publication of HUP0004070A2 publication Critical patent/HUP0004070A2/hu

2002-03-28 Publication of HUP0004070A3 publication Critical patent/HUP0004070A3/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

HU0004070A 1997-06-05 1998-06-02 Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione HUP0004070A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9711683.4A GB9711683D0 (en)	1997-06-05	1997-06-05	Composition
GBGB9712851.6A GB9712851D0 (en)	1997-06-18	1997-06-18	Composition
PCT/EP1998/003478 WO1998055122A1 (en)	1997-06-05	1998-06-02	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione

Publications (2)

Publication Number	Publication Date
HUP0004070A2 true HUP0004070A2 (hu)	2002-02-28
HUP0004070A3 HUP0004070A3 (en)	2002-03-28

Family

ID=26311662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0004070A HUP0004070A3 (en)	1997-06-05	1998-06-02	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione

Country Status (29)

Country	Link
EP (1)	EP0998284A1 (hu)
JP (1)	JP2001521553A (hu)
KR (1)	KR20010013410A (hu)
CN (3)	CN1526391A (hu)
AP (1)	AP1214A (hu)
AR (2)	AR015120A1 (hu)
AU (1)	AU8215098A (hu)
BG (1)	BG104048A (hu)
BR (1)	BR9810405A (hu)
CA (2)	CA2292629C (hu)
CO (1)	CO4940400A1 (hu)
DZ (1)	DZ2510A1 (hu)
EA (1)	EA002384B1 (hu)
GB (1)	GB9711683D0 (hu)
HU (1)	HUP0004070A3 (hu)
ID (1)	ID24264A (hu)
IL (1)	IL133074A0 (hu)
MX (1)	MXPA99011322A (hu)
NO (2)	NO995938L (hu)
NZ (2)	NZ523725A (hu)
OA (1)	OA11306A (hu)
PE (1)	PE78899A1 (hu)
PL (1)	PL337201A1 (hu)
SK (1)	SK164899A3 (hu)
TR (2)	TR199902963T2 (hu)
TW (1)	TW570797B (hu)
UY (1)	UY25032A1 (hu)
WO (1)	WO1998055122A1 (hu)
ZA (2)	ZA984826B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PE20010040A1 (es)	1999-04-23	2001-03-10	Smithkline Beecham Plc	Polimorfo de sal del acido maleico de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]-tiazolidina-2,4-diona
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
ATE246191T1 (de)	1999-04-23	2003-08-15	Smithkline Beecham Plc	Polymorph von 5-(4-(2-(n-methyl-n-(2- pyrdyl)amino)äthoxy)benzyl)thiazolidin-2,4-dion maleinsäuresalz
GB0021978D0 (en)	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
GB0127805D0 (en) *	2001-11-20	2002-01-09	Smithkline Beecham Plc	Pharmaceutical composition
AU2002350965A1 (en) *	2001-12-13	2003-06-23	Smithkline Beecham Plc	Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129876D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0129871D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130509D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
US7435741B2 (en)	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
DE06252444T8 (de) *	2006-05-09	2009-03-19	Teva Pharmaceutical Industries Ltd.	2-N-{5-[[4-[2-(Methyl-2-pyridinylamino)-ethoxy]-phenyl]-methyl]-2,4-thiazolidindion}-bernsteinsäure, Verfahren zur Herstellung und Zusammensetzungen mit Rosiglitazonmaleat
WO2015008234A1 (en) *	2013-07-17	2015-01-22	Glenmark Pharmaceuticals S.A.	Bicyclic heterocyclic compounds as ror gamma modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3856378T2 (de) *	1987-09-04	2000-05-11	Beecham Group P.L.C., Brentford	Substituierte Thiazolidindionderivate
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
WO1995021608A1 (en) *	1994-02-10	1995-08-17	Smithkline Beecham Plc	Use of insulin sensitisers for treating renal diseases
KR19990036290A (ko) *	1995-08-10	1999-05-25	로즈 암스트롱	비인슐린 의존성 진성 당뇨병 환자에 대한 외인성 인슐린 투여량의 감소 방법
AU7604596A (en) *	1995-11-17	1997-06-11	Warner-Lambert Company	A method of treating myotonic dystrophy
NZ314406A (en) *	1996-03-18	2000-12-22	Sankyo Co	Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
EP0921798A1 (en) *	1996-07-12	1999-06-16	Smithkline Beecham Plc	Novel treatment of leptine resistance

1997
- 1997-06-05 GB GBGB9711683.4A patent/GB9711683D0/en active Pending
1998
- 1998-06-02 CA CA002292629A patent/CA2292629C/en not_active Expired - Fee Related
- 1998-06-02 JP JP50158799A patent/JP2001521553A/ja not_active Ceased
- 1998-06-02 SK SK1648-99A patent/SK164899A3/sk unknown
- 1998-06-02 CN CNA2003101199090A patent/CN1526391A/zh active Pending
- 1998-06-02 EP EP98932144A patent/EP0998284A1/en not_active Withdrawn
- 1998-06-02 WO PCT/EP1998/003478 patent/WO1998055122A1/en not_active Application Discontinuation
- 1998-06-02 HU HU0004070A patent/HUP0004070A3/hu unknown
- 1998-06-02 IL IL13307498A patent/IL133074A0/xx unknown
- 1998-06-02 KR KR19997011411A patent/KR20010013410A/ko not_active Application Discontinuation
- 1998-06-02 EA EA199901116A patent/EA002384B1/ru not_active IP Right Cessation
- 1998-06-02 TR TR1999/02963T patent/TR199902963T2/xx unknown
- 1998-06-02 CA CA002333352A patent/CA2333352A1/en not_active Abandoned
- 1998-06-02 AP APAP/P/1999/001696A patent/AP1214A/en active
- 1998-06-02 ID IDW991520A patent/ID24264A/id unknown
- 1998-06-02 PL PL98337201A patent/PL337201A1/xx unknown
- 1998-06-02 CN CN98805686A patent/CN1112926C/zh not_active Expired - Lifetime
- 1998-06-02 NZ NZ523725A patent/NZ523725A/en unknown
- 1998-06-02 TR TR2000/02790T patent/TR200002790T2/xx unknown
- 1998-06-02 MX MXPA99011322A patent/MXPA99011322A/es unknown
- 1998-06-02 AU AU82150/98A patent/AU8215098A/en not_active Abandoned
- 1998-06-02 BR BR9810405-5A patent/BR9810405A/pt not_active IP Right Cessation
- 1998-06-03 DZ DZ980120A patent/DZ2510A1/xx active
- 1998-06-04 CO CO98031614A patent/CO4940400A1/es unknown
- 1998-06-04 AR ARP980102650A patent/AR015120A1/es not_active Application Discontinuation
- 1998-06-04 UY UY25032A patent/UY25032A1/es not_active IP Right Cessation
- 1998-06-04 ZA ZA9804826A patent/ZA984826B/xx unknown
- 1998-06-04 ZA ZA9811572A patent/ZA9811572B/xx unknown
- 1998-06-04 AR ARP980102649A patent/AR008198A1/es not_active Application Discontinuation
- 1998-06-05 PE PE1998000466A patent/PE78899A1/es not_active Application Discontinuation
- 1998-10-23 TW TW087117536A patent/TW570797B/zh not_active IP Right Cessation
1999
- 1999-12-02 OA OA9900267A patent/OA11306A/en unknown
- 1999-12-03 NO NO995938A patent/NO995938L/no not_active Application Discontinuation
- 1999-12-27 BG BG104048A patent/BG104048A/bg unknown
2001
- 2001-09-03 NZ NZ513922A patent/NZ513922A/xx unknown
2002
- 2002-11-05 CN CN02149972A patent/CN1430959A/zh active Pending
2004
- 2004-02-20 NO NO20040738A patent/NO20040738L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP2001521553A (ja)	2001-11-06
NO995938D0 (no)	1999-12-03
EA199901116A1 (ru)	2000-06-26
PL337201A1 (en)	2000-08-14
AR015120A1 (es)	2001-04-18
BR9810405A (pt)	2000-08-29
AP1214A (en)	2003-10-08
WO1998055122A1 (en)	1998-12-10
CN1430959A (zh)	2003-07-23
CA2292629A1 (en)	1998-12-10
AU8215098A (en)	1998-12-21
IL133074A0 (en)	2001-03-19
ID24264A (id)	2000-07-13
PE78899A1 (es)	1999-10-22
CA2292629C (en)	2004-01-06
KR20010013410A (ko)	2001-02-26
BG104048A (bg)	2000-07-31
NZ513922A (en)	2001-09-28
ZA984826B (en)	1999-08-03
NZ523725A (en)	2004-09-24
CO4940400A1 (es)	2000-07-24
UY25032A1 (es)	1998-11-26
SK164899A3 (en)	2000-11-07
ZA9811572B (en)	1999-07-22
DZ2510A1 (fr)	2003-01-25
TR199902963T2 (xx)	2000-02-21
TR200002790T2 (tr)	2001-11-21
CN1259050A (zh)	2000-07-05
AP9901696A0 (en)	1999-12-31
EA002384B1 (ru)	2002-04-25
TW570797B (en)	2004-01-11
NO995938L (no)	2000-02-02
CN1526391A (zh)	2004-09-08
CN1112926C (zh)	2003-07-02
HUP0004070A3 (en)	2002-03-28
GB9711683D0 (en)	1997-08-06
AR008198A1 (es)	1999-12-29
MXPA99011322A (es)	2004-12-02
OA11306A (en)	2003-10-22
EP0998284A1 (en)	2000-05-10
CA2333352A1 (en)	1998-12-10
NO20040738L (no)	2000-02-02

Publication	Publication Date	Title
IL151425A0 (en)	2003-04-10	Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl) amino)ethoxy]benzyl] thiazolidine-2,4-dione
AU4600493A (en)	1994-06-16	Monohydrate of 5-(2-(4-(1,2 benzisothiazol-3-yl) -1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride
IL146111A0 (en)	2002-07-25	5-[4-[2-(n-methyl-n-(2-pyridyl) amino)ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt
PL341146A1 (en)	2001-03-26	Maleic 5-[4-[2-(n-methyl-n-(2-pyridil)amino)ethoxy]benzyl]thiazolydin-2,4-dione salt hydrate as a pharmacological agent
HUP0004070A3 (en)	2002-03-28	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
IL155036A0 (en)	2003-10-31	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and pharmaceutical compositions containing the same
AP2000001830A0 (en)	2000-06-30	Hydrate of 5-[4-[2-(n-methyl-n-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
ZA984795B (en)	1999-01-04	New thiazolidinedione oxazolidinedione and oxadiazolidinedione derivatives
AU2002343036A1 (en)	2003-06-10	5-(4-(2-(n-methyl-n-(2-pyridyl)amido)ethoxy)benzyl)thiazolidine-2,4-dione and pharmaceutical compositions comprising the same
IL154724A0 (en)	2003-10-31	The hydrochloride salt of 5-[4- [2- (n-methyl-n- (2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2, 4-dione
IL160144A0 (en)	2004-06-20	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2, 4-dione
IL188116A0 (en)	2008-03-20	Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2,4-dione
HUP9802874A3 (en)	2000-02-28	Process for making 2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole using methyldithiocarbazinate
GB0021784D0 (en)	2000-10-18	Novel pharmaceutical
AU6255001A (en)	2001-12-17	5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide as pharmaceutical
AU2002352481A1 (en)	2003-07-09	5- (4- (2- (n-methyl-n- (2-pyridil) amino) ethoxy) benzyl) thiazolidine-2, 4-dione nephtalenesulfonate salt and use against diabetes mellitus
IL166189A (en)	2005-07-25	5-{4-[2-(n-methyl-n-(2-pyridyl) amino) ethoxy] benzyl}-5-{1-[2, 4-dioxothiazolidine-5-yl]-1-[4-(2-(n-methyl-n-(2-pyridyl) amino) ethoxy) phenyl] methyl}-2,4-thiazolidinedione and tautomeric form, salt or solvate thereof
AU2002222305A1 (en)	2002-07-08	5-'4-'2-(n-methyl-n- (2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione mesylate salt
SI1265893T1 (sl)	2005-12-31	Hidrokloridne soli 5-(4-(2-(n-metil-n-(2-piridil)amino)etoksi)benzil)tiazolidin-2,4-diona