HUP0004544A2 - Angiotenzin-átalakító enzim inhibitora és diuretikum kombinációjának alkalmazása mikrokeringési rendellenességek kezelésére szolgáló gyógyászati készítmény előállítására - Google Patents
Angiotenzin-átalakító enzim inhibitora és diuretikum kombinációjának alkalmazása mikrokeringési rendellenességek kezelésére szolgáló gyógyászati készítmény előállításáraInfo
- Publication number
- HUP0004544A2 HUP0004544A2 HU0004544A HUP0004544A HUP0004544A2 HU P0004544 A2 HUP0004544 A2 HU P0004544A2 HU 0004544 A HU0004544 A HU 0004544A HU P0004544 A HUP0004544 A HU P0004544A HU P0004544 A2 HUP0004544 A2 HU P0004544A2
- Authority
- HU
- Hungary
- Prior art keywords
- diuretic
- converting enzyme
- enzyme inhibitor
- pharmaceutical composition
- microcirculation disorders
- Prior art date
Links
- 239000005541 ACE inhibitor Substances 0.000 title abstract 2
- 239000002934 diuretic Substances 0.000 title abstract 2
- 230000001882 diuretic effect Effects 0.000 title abstract 2
- 230000004089 microcirculation Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 108010072661 Angiotensin Amide Proteins 0.000 title 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 101710129690 Angiotensin-converting enzyme inhibitor Proteins 0.000 abstract 1
- 101710086378 Bradykinin-potentiating and C-type natriuretic peptides Proteins 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány tárgyát angiotenzin-átalakító enzim inhibitora (CEI) ésegy diuretikum kombinációjának arteriolo-kapilláris mikrokeringésirendellenességek kezelésére alkalmas gyógyászati készítményekelőállítására történő alkalmazása képezi. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9714485A FR2771010B1 (fr) | 1997-11-19 | 1997-11-19 | Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires |
PCT/FR1998/000411 WO1999025374A1 (fr) | 1997-11-19 | 1998-03-03 | Combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0004544A2 true HUP0004544A2 (hu) | 2001-06-28 |
HUP0004544A3 HUP0004544A3 (en) | 2001-07-30 |
HU226022B1 HU226022B1 (en) | 2008-03-28 |
Family
ID=9513523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0004544A HU226022B1 (en) | 1997-11-19 | 1998-03-03 | Process for preparation pharmaceutical composition combination of hypertensin converting enzyme inhibitor with a diuretic for treating microcirculation disorders |
Country Status (21)
Country | Link |
---|---|
US (1) | US6653336B1 (hu) |
EP (1) | EP1032414B1 (hu) |
JP (1) | JP2001523646A (hu) |
CN (1) | CN1227029C (hu) |
AT (1) | ATE239500T1 (hu) |
AU (1) | AU740748B2 (hu) |
BR (1) | BR9814885A (hu) |
CA (1) | CA2310136C (hu) |
DE (1) | DE69814444T2 (hu) |
DK (1) | DK1032414T3 (hu) |
EA (1) | EA002968B1 (hu) |
ES (1) | ES2198708T3 (hu) |
FR (1) | FR2771010B1 (hu) |
HK (1) | HK1033096A1 (hu) |
HU (1) | HU226022B1 (hu) |
NO (1) | NO20002479D0 (hu) |
NZ (1) | NZ504220A (hu) |
PL (1) | PL340561A1 (hu) |
PT (1) | PT1032414E (hu) |
WO (1) | WO1999025374A1 (hu) |
ZA (1) | ZA986673B (hu) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2811320B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811319B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811318B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
US20040156903A1 (en) * | 2002-05-22 | 2004-08-12 | Abrams Andrew L.. | Metering and packaging of controlled release medication |
NZ529696A (en) * | 2001-05-31 | 2008-07-31 | Microdose Technologies Inc | Metering and packaging of controlled release medication |
FR2841140B1 (fr) * | 2002-06-24 | 2004-10-01 | Servier Lab | Microcapsules pour la liberation retardee et controlee du perindopril |
CA2537180A1 (en) * | 2003-08-29 | 2005-03-10 | Cotherix, Inc. | Cicletanine in combination with oral antidiabetic and/or blood lipid-lowering agents as a combination therapy for diabetes and metabolic syndrome |
CN1292747C (zh) * | 2003-09-16 | 2007-01-03 | 广东省心血管病研究所 | 一种用于治疗高血压的复方制剂 |
DE102004019845A1 (de) * | 2004-03-29 | 2005-10-20 | Krka Tovarna Zdravil D D | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung |
PT1729739T (pt) * | 2004-03-29 | 2016-12-01 | Servier Lab | Processo para a preparação de uma composição farmacêutica sólida |
SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
DE102004062257A1 (de) * | 2004-12-23 | 2006-07-06 | Merckle Gmbh | Direkt verpresste Indapamid-Tabletten mit verzögerter Wirkstofffreisetzung |
MY138209A (en) * | 2005-03-11 | 2009-05-29 | Servier Lab | New (y) crystalline form of perindopril tert-butylamine salt, a process for its preparation and pharmaceutical compositions containing it. |
BRPI0615607A2 (pt) * | 2005-08-30 | 2011-05-24 | Lek Pharmaceuticals | composição farmacêutica compreendendo perindopril ou seus sais |
DE102005058166A1 (de) * | 2005-12-05 | 2007-06-06 | Hexal Ag | Matrixkontrolliertes transdermales System mit Amin-Salzen der ACE-Hemmer-Dicarbonsäuren |
WO2008068577A2 (en) * | 2006-12-01 | 2008-06-12 | Glenmark Pharmaceuticals Limited | Pharmaceutical compositions |
SI22543A (sl) | 2007-06-27 | 2008-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nove soli perindoprila |
AU2012315586B2 (en) | 2011-09-29 | 2017-07-20 | Mayo Foundation For Medical Education And Research | Aromatic-cationic peptides and methods for using same |
RU2618471C2 (ru) * | 2012-12-03 | 2017-05-03 | Закрытое Акционерное Общество "Вертекс" | Пероральная фармацевтическая композиция диуретика и ингибитора АПФ в микронизированной форме, лекарственное средство и его применение |
CN113286581A (zh) * | 2019-01-09 | 2021-08-20 | 扶桑药品工业株式会社 | 用于治疗视网膜疾病的眼内或者口服给药用药物组合物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK9200258U4 (da) * | 1992-03-11 | 1993-07-23 | Merck & Co Inc | Farmaceutisk præparat indeholdende enalapril til brug mod hypertension |
JPH11500140A (ja) * | 1995-03-16 | 1999-01-06 | ファイザー・インコーポレーテッド | アムロジピン、アムロジピン塩、もしくはフェロジピンとace阻害薬とを含有する組成物 |
-
1997
- 1997-11-19 FR FR9714485A patent/FR2771010B1/fr not_active Expired - Fee Related
-
1998
- 1998-03-03 PL PL98340561A patent/PL340561A1/xx unknown
- 1998-03-03 HU HU0004544A patent/HU226022B1/hu unknown
- 1998-03-03 US US09/554,715 patent/US6653336B1/en not_active Expired - Lifetime
- 1998-03-03 DK DK98913813T patent/DK1032414T3/da active
- 1998-03-03 PT PT98913813T patent/PT1032414E/pt unknown
- 1998-03-03 EA EA200000536A patent/EA002968B1/ru not_active IP Right Cessation
- 1998-03-03 AT AT98913813T patent/ATE239500T1/de active
- 1998-03-03 WO PCT/FR1998/000411 patent/WO1999025374A1/fr active IP Right Grant
- 1998-03-03 BR BR9814885-0A patent/BR9814885A/pt not_active Application Discontinuation
- 1998-03-03 AU AU68377/98A patent/AU740748B2/en not_active Revoked
- 1998-03-03 NZ NZ504220A patent/NZ504220A/en not_active IP Right Cessation
- 1998-03-03 CA CA002310136A patent/CA2310136C/fr not_active Expired - Lifetime
- 1998-03-03 EP EP98913813A patent/EP1032414B1/fr not_active Expired - Lifetime
- 1998-03-03 DE DE69814444T patent/DE69814444T2/de not_active Expired - Lifetime
- 1998-03-03 ES ES98913813T patent/ES2198708T3/es not_active Expired - Lifetime
- 1998-03-03 CN CNB988113163A patent/CN1227029C/zh not_active Expired - Lifetime
- 1998-03-03 JP JP2000520807A patent/JP2001523646A/ja active Pending
- 1998-07-27 ZA ZA986673A patent/ZA986673B/xx unknown
-
2000
- 2000-05-12 NO NO20002479A patent/NO20002479D0/no not_active Application Discontinuation
-
2001
- 2001-06-04 HK HK01103825A patent/HK1033096A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT1032414E (pt) | 2003-08-29 |
HU226022B1 (en) | 2008-03-28 |
JP2001523646A (ja) | 2001-11-27 |
PL340561A1 (en) | 2001-02-12 |
ZA986673B (en) | 1999-02-04 |
ATE239500T1 (de) | 2003-05-15 |
ES2198708T3 (es) | 2004-02-01 |
NO20002479L (no) | 2000-05-12 |
FR2771010B1 (fr) | 2003-08-15 |
DE69814444D1 (de) | 2003-06-12 |
EP1032414B1 (fr) | 2003-05-07 |
CN1227029C (zh) | 2005-11-16 |
DK1032414T3 (da) | 2003-09-01 |
CA2310136A1 (fr) | 1999-05-27 |
HK1033096A1 (en) | 2001-08-17 |
DE69814444T2 (de) | 2004-03-18 |
US6653336B1 (en) | 2003-11-25 |
EA200000536A1 (ru) | 2000-10-30 |
HUP0004544A3 (en) | 2001-07-30 |
BR9814885A (pt) | 2000-10-03 |
WO1999025374A1 (fr) | 1999-05-27 |
EP1032414A1 (fr) | 2000-09-06 |
NZ504220A (en) | 2003-05-30 |
AU740748B2 (en) | 2001-11-15 |
NO20002479D0 (no) | 2000-05-12 |
EA002968B1 (ru) | 2002-12-26 |
CA2310136C (fr) | 2004-04-20 |
CN1279615A (zh) | 2001-01-10 |
FR2771010A1 (fr) | 1999-05-21 |
AU6837798A (en) | 1999-06-07 |
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