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HUE036635T2 - Eljárások zárványtestekbõl származó G-CSF konformációjának helyreállítására - Google Patents

Eljárások zárványtestekbõl származó G-CSF konformációjának helyreállítására

Info

Publication number
HUE036635T2
HUE036635T2 HUE13709470A HUE13709470A HUE036635T2 HU E036635 T2 HUE036635 T2 HU E036635T2 HU E13709470 A HUE13709470 A HU E13709470A HU E13709470 A HUE13709470 A HU E13709470A HU E036635 T2 HUE036635 T2 HU E036635T2
Authority
HU
Hungary
Prior art keywords
refolding
csf
methods
inclusion bodies
inclusion
Prior art date
Application number
HUE13709470A
Other languages
English (en)
Inventor
Ferenc Felfoeldi
Andras Ballagi
Janos Becsi
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of HUE036635T2 publication Critical patent/HUE036635T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
HUE13709470A 2012-03-19 2013-03-18 Eljárások zárványtestekbõl származó G-CSF konformációjának helyreállítására HUE036635T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1200172A HUP1200172A2 (en) 2012-03-19 2012-03-19 Methods for refolding g-csf from inclusion bodies

Publications (1)

Publication Number Publication Date
HUE036635T2 true HUE036635T2 (hu) 2018-07-30

Family

ID=89990649

Family Applications (2)

Application Number Title Priority Date Filing Date
HU1200172A HUP1200172A2 (en) 2012-03-19 2012-03-19 Methods for refolding g-csf from inclusion bodies
HUE13709470A HUE036635T2 (hu) 2012-03-19 2013-03-18 Eljárások zárványtestekbõl származó G-CSF konformációjának helyreállítására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU1200172A HUP1200172A2 (en) 2012-03-19 2012-03-19 Methods for refolding g-csf from inclusion bodies

Country Status (15)

Country Link
US (1) US9458207B2 (hu)
EP (1) EP2828287B1 (hu)
JP (1) JP6282630B2 (hu)
KR (1) KR101933753B1 (hu)
CN (1) CN104540846B (hu)
CA (1) CA2867796C (hu)
DK (1) DK2828287T3 (hu)
ES (1) ES2664231T3 (hu)
HR (1) HRP20180234T1 (hu)
HU (2) HUP1200172A2 (hu)
LT (1) LT2828287T (hu)
NO (1) NO2828287T3 (hu)
PL (1) PL2828287T3 (hu)
SI (1) SI2828287T1 (hu)
WO (1) WO2013068603A2 (hu)

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WO2012015908A2 (en) 2010-07-30 2012-02-02 Millipore Corporation Chromatography media and method
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
EP3084776B1 (de) * 2013-12-19 2018-06-20 Fraunhofer Gesellschaft zur Förderung der Angewand Transparente nanodrahtelektrode mit funktionaler organischer schicht
KR102072529B1 (ko) 2014-09-02 2020-02-25 이엠디 밀리포어 코포레이션 나노-피브릴화된 표면 특징을 갖는 고표면적 섬유 매질
EP3230299A1 (en) * 2014-12-08 2017-10-18 EMD Millipore Corporation Mixed bed ion exchange adsorber
CN108368512B (zh) * 2016-04-18 2020-03-27 江苏恒瑞医药股份有限公司 一种重组人粒细胞集落刺激因子的制备方法
CN113866327A (zh) * 2016-12-12 2021-12-31 邢玉伟 Lhj增溶剂在难溶食品添加剂定量测定中的应用
WO2019246153A1 (en) * 2018-06-19 2019-12-26 Bristol-Myers Squibb Company Methods of purifying proteins using chromatography
AU2020261942A1 (en) * 2019-04-24 2021-11-04 Tanvex Biopharma Usa, Inc. Process for preparing granulocyte-colony stimulating factor
AU2020311357A1 (en) * 2019-07-09 2022-01-27 Hopp, Jennifer Renee Temperature-controlled purification of granulocyte-colony stimulating factor

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DE3537708A1 (de) 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
US5681720A (en) 1986-12-23 1997-10-28 Kyowa Hakko Co., Ltd. DNA encoding human granulocyte colony stimulating factor plasmids and host cells comprising same, and methods of expressing the encoded polypeptide
EP0347041A3 (en) * 1988-05-13 1990-11-22 Amgen Inc. Compositions and method for treating or preventing infections in animals
US5055555A (en) 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
DE4242919A1 (de) * 1992-12-18 1994-06-23 Boehringer Mannheim Gmbh Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF
KR100241257B1 (ko) * 1997-05-22 2000-02-01 한승수 인체 과립구 콜로니 자극 인자 활성물질 및 그것의 제조방법
US7153943B2 (en) * 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
US7270809B2 (en) * 1997-07-14 2007-09-18 Bolder Biotechnology, Inc. Cysteine variants of alpha interferon-2
AU4975699A (en) 1998-07-09 2000-02-01 University Technology Corporation High pressure refolding of protein aggregates and inclusion bodies
FR2796071B1 (fr) 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes
US6606183B2 (en) * 1999-12-24 2003-08-12 Nippon Oil Corporation Method for producing a cell for an electrochromic mirror and an electrochromic mirror
CN1318443C (zh) 2000-05-16 2007-05-30 博尔德生物技术公司 含游离半胱氨酸残基的蛋白重折叠的方法
US20020150979A1 (en) * 2000-10-04 2002-10-17 Naokazu Naitou Process for producing a protein
SI21102A (sl) 2001-12-19 2003-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
WO2004001056A1 (en) * 2002-06-24 2003-12-31 Dr. Reddy's Laboratories Ltd. Process for preparing g-csf
SI21273A (sl) 2002-07-31 2004-02-29 LEK farmacevtska dru�ba d.d. Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
DE102004041639A1 (de) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
US20080171857A1 (en) * 2005-03-17 2008-07-17 Uma Devi Komath Process for the Purification of Recombinant Granulocyte-Colony Stimulating Factor
KR100694994B1 (ko) 2005-06-13 2007-03-14 씨제이 주식회사 사람 과립구 콜로니 형성인자 동종체
DE102005033250A1 (de) * 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
GB0605684D0 (en) 2006-03-21 2006-05-03 Sicor Biotech Uab Method For Purifying Granulocyte-Colony Stimulating Factor
US8617531B2 (en) * 2006-12-14 2013-12-31 Bolder Biotechnology, Inc. Methods of making proteins and peptides containing a single free cysteine
WO2008096370A2 (en) * 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
EP2443135A1 (en) 2009-06-16 2012-04-25 Lupin Ltd. Process for purification of recombinant human granulocyte colony stimulating factor
RS53010B (en) * 2009-12-31 2014-04-30 Arven Ilac Sanayi Ve Ticaret A.S. NEW PROCEDURE FOR PREPARATION OF G-CSF (GRANULOCITE COLONY STIMULATION FACTOR)
BR112012022518A2 (pt) * 2010-03-17 2020-10-13 Biogenerix Gmbh método para obtenção de g- csf recombinante humano biologicamente ativo
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására

Also Published As

Publication number Publication date
SI2828287T1 (en) 2018-04-30
JP2015512377A (ja) 2015-04-27
CN104540846A (zh) 2015-04-22
WO2013068603A2 (en) 2013-05-16
CN104540846B (zh) 2017-05-24
NO2828287T3 (hu) 2018-06-16
JP6282630B2 (ja) 2018-02-21
CA2867796C (en) 2019-10-08
EP2828287A2 (en) 2015-01-28
HUP1200172A2 (en) 2013-10-28
US20150057439A1 (en) 2015-02-26
HRP20180234T1 (hr) 2018-03-23
DK2828287T3 (en) 2018-02-26
KR20140142724A (ko) 2014-12-12
CA2867796A1 (en) 2013-05-16
KR101933753B1 (ko) 2018-12-28
LT2828287T (lt) 2018-03-12
ES2664231T3 (es) 2018-04-18
WO2013068603A3 (en) 2013-08-29
PL2828287T3 (pl) 2018-05-30
US9458207B2 (en) 2016-10-04
EP2828287B1 (en) 2018-01-17

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