HUE056593T2 - Fuzionált pentaciklusos imidazolszármazékok mint a TNF-aktivitás modulátorai - Google Patents

Fuzionált pentaciklusos imidazolszármazékok mint a TNF-aktivitás modulátorai

Info

Publication number: HUE056593T2
Authority: HU; Hungary
Prior art keywords: modulators; imidazole derivatives; tnf activity; fused pentacyclic; pentacyclic imidazole
Prior art date: 2017-04-25

Application number

HUE18719178A

Other languages

English (en)

Inventor

Daniel Christopher Brookings

Original Assignee

UCB Biopharma SRL

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-04-25

Filing date

2018-04-24

Publication date

2022-02-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58632834&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE056593(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2018-04-24 Application filed by UCB Biopharma SRL, Sanofi Sa filed Critical UCB Biopharma SRL

2022-02-28 Publication of HUE056593T2 publication Critical patent/HUE056593T2/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/18—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Diabetes (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Dermatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

HUE18719178A 2017-04-25 2018-04-24 Fuzionált pentaciklusos imidazolszármazékok mint a TNF-aktivitás modulátorai HUE056593T2 (hu)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP17168027		2017-04-25

Publications (1)

Publication Number	Publication Date
HUE056593T2 true HUE056593T2 (hu)	2022-02-28

Family

ID=58632834

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HUE18719178A HUE056593T2 (hu)	2017-04-25	2018-04-24	Fuzionált pentaciklusos imidazolszármazékok mint a TNF-aktivitás modulátorai

Country Status (33)

Country	Link
US (3)	US10980814B2 (hu)
EP (2)	EP3939980B1 (hu)
JP (2)	JP7083358B2 (hu)
KR (1)	KR102565132B1 (hu)
CN (1)	CN110582495B (hu)
AR (1)	AR111426A1 (hu)
AU (1)	AU2018259040B2 (hu)
BR (1)	BR112019020314A2 (hu)
CA (1)	CA3058980A1 (hu)
CL (1)	CL2019002875A1 (hu)
CO (1)	CO2019012856A2 (hu)
CR (1)	CR20190526A (hu)
DK (1)	DK3615534T3 (hu)
EA (1)	EA039049B1 (hu)
ES (2)	ES2956555T3 (hu)
HR (1)	HRP20211927T1 (hu)
HU (1)	HUE056593T2 (hu)
IL (1)	IL269890B (hu)
LT (1)	LT3615534T (hu)
MA (2)	MA49055B1 (hu)
MX (1)	MX2019012443A (hu)
MY (1)	MY197212A (hu)
PE (1)	PE20200662A1 (hu)
PH (1)	PH12019502182A1 (hu)
PL (2)	PL3615534T3 (hu)
PT (2)	PT3939980T (hu)
RS (1)	RS62596B1 (hu)
SG (1)	SG11201908871SA (hu)
SI (1)	SI3615534T1 (hu)
TW (1)	TWI801378B (hu)
UY (1)	UY37700A (hu)
WO (1)	WO2018197503A1 (hu)
ZA (1)	ZA201906255B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN109219609B (zh) *	2016-04-01	2022-02-01	Ucb生物制药私人有限公司	作为tnf活性调节剂的稠合六环咪唑衍生物
JP7429694B2 (ja) *	2018-10-24	2024-02-08	ユーシービーバイオファルマエスアールエル	Ｔｎｆ活性のモジュレータとしての縮合五環式イミダゾール誘導体
WO2024223740A1 (en)	2023-04-26	2024-10-31	Sanofi	Treating psoriasis using a small molecule inhibitor of tumor necrosis factor alpha

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN104428293B (zh) *	2012-06-11	2018-06-08	Ucb生物制药私人有限公司	调节TNFα的苯并咪唑类
CN104619709B (zh) *	2012-07-13	2016-11-09	Ucb生物制药私人有限公司	作为tnf活性调节剂的咪唑并吡啶衍生物
GB201212513D0 (en) *	2012-07-13	2012-08-29	Ucb Pharma Sa	Therapeutic agents
GB201321728D0 (en)	2013-12-09	2014-01-22	Ucb Pharma Sa	Therapeutic agents
TWI719949B (zh) *	2014-10-03	2021-03-01	比利時商Ｕｃｂ生物製藥公司	稠合五環咪唑衍生物
AR104291A1 (es) *	2015-04-17	2017-07-12	Abbvie Inc	Moduladores tricíclicos de la señalización por tnf

2018
- 2018-04-24 SI SI201830491T patent/SI3615534T1/sl unknown
- 2018-04-24 PL PL18719178T patent/PL3615534T3/pl unknown
- 2018-04-24 MY MYPI2019005903A patent/MY197212A/en unknown
- 2018-04-24 BR BR112019020314A patent/BR112019020314A2/pt unknown
- 2018-04-24 MX MX2019012443A patent/MX2019012443A/es unknown
- 2018-04-24 CA CA3058980A patent/CA3058980A1/en active Pending
- 2018-04-24 HU HUE18719178A patent/HUE056593T2/hu unknown
- 2018-04-24 ES ES21189378T patent/ES2956555T3/es active Active
- 2018-04-24 PT PT211893789T patent/PT3939980T/pt unknown
- 2018-04-24 PT PT187191788T patent/PT3615534T/pt unknown
- 2018-04-24 EA EA201992407A patent/EA039049B1/ru unknown
- 2018-04-24 SG SG11201908871S patent/SG11201908871SA/en unknown
- 2018-04-24 PE PE2019002028A patent/PE20200662A1/es unknown
- 2018-04-24 CN CN201880025894.6A patent/CN110582495B/zh active Active
- 2018-04-24 HR HRP20211927TT patent/HRP20211927T1/hr unknown
- 2018-04-24 CR CR20190526A patent/CR20190526A/es unknown
- 2018-04-24 PL PL21189378.9T patent/PL3939980T3/pl unknown
- 2018-04-24 DK DK18719178.8T patent/DK3615534T3/da active
- 2018-04-24 LT LTEPPCT/EP2018/060489T patent/LT3615534T/lt unknown
- 2018-04-24 TW TW107113777A patent/TWI801378B/zh active
- 2018-04-24 AU AU2018259040A patent/AU2018259040B2/en active Active
- 2018-04-24 EP EP21189378.9A patent/EP3939980B1/en active Active
- 2018-04-24 RS RS20211403A patent/RS62596B1/sr unknown
- 2018-04-24 US US16/497,217 patent/US10980814B2/en active Active
- 2018-04-24 ES ES18719178T patent/ES2893807T3/es active Active
- 2018-04-24 JP JP2019556874A patent/JP7083358B2/ja active Active
- 2018-04-24 EP EP18719178.8A patent/EP3615534B1/en active Active
- 2018-04-24 WO PCT/EP2018/060489 patent/WO2018197503A1/en active Application Filing
- 2018-04-24 KR KR1020197034032A patent/KR102565132B1/ko active IP Right Grant
- 2018-04-24 MA MA49055A patent/MA49055B1/fr unknown
- 2018-04-25 AR ARP180101067A patent/AR111426A1/es unknown
- 2018-04-25 UY UY0001037700A patent/UY37700A/es not_active Application Discontinuation
- 2018-08-24 MA MA57699A patent/MA57699B1/fr unknown
2019
- 2019-09-20 ZA ZA2019/06255A patent/ZA201906255B/en unknown
- 2019-09-23 PH PH12019502182A patent/PH12019502182A1/en unknown
- 2019-10-07 IL IL269890A patent/IL269890B/en unknown
- 2019-10-09 CL CL2019002875A patent/CL2019002875A1/es unknown
- 2019-11-18 CO CONC2019/0012856A patent/CO2019012856A2/es unknown
2021
- 2021-02-15 US US17/176,018 patent/US20210252012A1/en not_active Abandoned
2022
- 2022-05-31 JP JP2022088172A patent/JP7299382B2/ja active Active
2023
- 2023-02-27 US US18/175,030 patent/US20230250105A1/en active Pending

Also Published As

Publication number	Publication date
WO2018197503A1 (en)	2018-11-01
PL3939980T3 (pl)	2024-02-05
ZA201906255B (en)	2021-01-27
PL3615534T3 (pl)	2022-01-31
CA3058980A1 (en)	2018-11-01
EP3615534A1 (en)	2020-03-04
JP7299382B2 (ja)	2023-06-27
ES2956555T3 (es)	2023-12-22
MY197212A (en)	2023-06-01
SG11201908871SA (en)	2019-10-30
PH12019502182A1 (en)	2020-06-08
CN110582495B (zh)	2022-04-01
PT3939980T (pt)	2023-08-07
EA039049B1 (ru)	2021-11-26
PT3615534T (pt)	2021-10-21
MA57699B1 (fr)	2023-11-30
CR20190526A (es)	2020-01-07
SI3615534T1 (sl)	2022-01-31
US20210252012A1 (en)	2021-08-19
US20230250105A1 (en)	2023-08-10
UY37700A (es)	2018-11-30
NZ758198A (en)	2024-01-26
DK3615534T3 (da)	2021-10-18
MX2019012443A (es)	2020-01-13
RS62596B1 (sr)	2021-12-31
EA201992407A1 (ru)	2020-04-06
JP2022116233A (ja)	2022-08-09
US10980814B2 (en)	2021-04-20
AU2018259040B2 (en)	2022-04-28
EP3939980A1 (en)	2022-01-19
JP2020517637A (ja)	2020-06-18
US20200046723A1 (en)	2020-02-13
TW201841918A (zh)	2018-12-01
EP3939980B1 (en)	2023-07-26
ES2893807T3 (es)	2022-02-10
KR20190141200A (ko)	2019-12-23
MA49055A (fr)	2021-05-05
CO2019012856A2 (es)	2020-01-17
TWI801378B (zh)	2023-05-11
JP7083358B2 (ja)	2022-06-10
PE20200662A1 (es)	2020-06-11
MA49055B1 (fr)	2021-12-31
IL269890B (en)	2022-03-01
EP3615534B1 (en)	2021-09-15
CL2019002875A1 (es)	2020-03-06
AR111426A1 (es)	2019-07-10
AU2018259040A1 (en)	2019-10-31
KR102565132B1 (ko)	2023-08-08
BR112019020314A2 (pt)	2020-04-28
CN110582495A (zh)	2019-12-17
LT3615534T (lt)	2021-11-25
HRP20211927T1 (hr)	2022-03-18

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IL255420A0 (en)	2017-12-31	Selective modulators of gpr55 receptor activity: chromopyrazole derivatives
IL274231A (en)	2020-06-30	Modulators of ENAC expression
PT3201196T (pt)	2021-09-02	Derivados de imidazol pentacíclicos fusionados