HUE048579T2 - Egyetlen, belsõ citozinhoz kapcsolt fluorofór jelet tartalmazó nukleinsav-próba hurok-közvetített izotermális amplifikációban történõ alkalmazásra - Google Patents
Egyetlen, belsõ citozinhoz kapcsolt fluorofór jelet tartalmazó nukleinsav-próba hurok-közvetített izotermális amplifikációban történõ alkalmazásraInfo
- Publication number
- HUE048579T2 HUE048579T2 HUE14793265A HUE14793265A HUE048579T2 HU E048579 T2 HUE048579 T2 HU E048579T2 HU E14793265 A HUE14793265 A HU E14793265A HU E14793265 A HUE14793265 A HU E14793265A HU E048579 T2 HUE048579 T2 HU E048579T2
- Authority
- HU
- Hungary
- Prior art keywords
- nucleic acid
- acid probe
- isothermal amplification
- mediated isothermal
- label bound
- Prior art date
Links
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title 2
- 238000007397 LAMP assay Methods 0.000 title 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 title 1
- 229940104302 cytosine Drugs 0.000 title 1
- 239000002853 nucleic acid probe Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/101—Linear amplification, i.e. non exponential
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/119—Strand displacement amplification [SDA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
- C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
- C12Q2533/101—Primer extension
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/107—Alteration in the property of hybridised versus free label oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1319180.4A GB201319180D0 (en) | 2013-10-30 | 2013-10-30 | Nucleic acid probe |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE048579T2 true HUE048579T2 (hu) | 2020-07-28 |
Family
ID=49767396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14793265A HUE048579T2 (hu) | 2013-10-30 | 2014-10-30 | Egyetlen, belsõ citozinhoz kapcsolt fluorofór jelet tartalmazó nukleinsav-próba hurok-közvetített izotermális amplifikációban történõ alkalmazásra |
Country Status (21)
Country | Link |
---|---|
US (2) | US20160273029A1 (hu) |
EP (1) | EP3063292B1 (hu) |
JP (2) | JP2016534722A (hu) |
CN (1) | CN105899674A (hu) |
AU (2) | AU2014343439A1 (hu) |
CA (1) | CA2926317C (hu) |
CY (1) | CY1124064T1 (hu) |
DK (1) | DK3063292T3 (hu) |
ES (1) | ES2773313T3 (hu) |
GB (2) | GB201319180D0 (hu) |
HR (1) | HRP20200264T1 (hu) |
HU (1) | HUE048579T2 (hu) |
LT (1) | LT3063292T (hu) |
PL (1) | PL3063292T3 (hu) |
PT (1) | PT3063292T (hu) |
RS (1) | RS59988B1 (hu) |
RU (1) | RU2668154C2 (hu) |
SA (1) | SA516371023B1 (hu) |
SI (1) | SI3063292T1 (hu) |
WO (1) | WO2015063498A2 (hu) |
ZA (1) | ZA201602247B (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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GB201402591D0 (en) * | 2014-02-14 | 2014-04-02 | Memo Therapeutics Ag | Method for recovering two or more genes, or gene products, encoding an immunoreceptor |
KR101875662B1 (ko) * | 2015-12-01 | 2018-08-02 | 에스디 바이오센서 주식회사 | 등온 핵산 증폭을 위한 리포터 염료, 퀀처가 포함되는 등온 기반 이중 기능성 올리고뉴클레오타이드 및 이를 이용한 핵산 증폭과 측정 방법 |
JP2019507606A (ja) * | 2015-12-18 | 2019-03-22 | セルフディアグノスティックス・ドイチュラント・ゲーエムベーハー | 性的感染症の病原体の検出方法 |
CN110177887B (zh) * | 2016-11-10 | 2024-10-29 | 达丽斯生物医学公司 | 用于扩增和检测沙眼衣原体的多核苷酸 |
EP3538538A4 (en) * | 2016-11-10 | 2020-11-04 | Talis Biomedical Corporation | POLYNUCLEOTIDES FOR THE AMPLIFICATION AND DETECTION OF NEISSERIA GONORRHOEAE |
CN107022645A (zh) * | 2017-06-14 | 2017-08-08 | 苏州承美生物科技有限公司 | 检测泌尿生殖道病原体淋球菌的分子信标探针及试剂盒 |
US10450616B1 (en) * | 2018-05-09 | 2019-10-22 | Talis Biomedical Corporation | Polynucleotides for the amplification and detection of Chlamydia trachomatis |
KR102705173B1 (ko) * | 2018-11-30 | 2024-09-12 | 삼성디스플레이 주식회사 | 표시패널 및 이를 포함하는 전자장치 |
US10954572B2 (en) * | 2019-07-25 | 2021-03-23 | Talis Biomedical Corporation | Polynucleotides for the amplification and detection of Neisseria gonorrhoeae |
US11891662B2 (en) | 2019-12-02 | 2024-02-06 | Talis Biomedical Corporation | Polynucleotides for amplification and detection of human beta actin |
PL435634A1 (pl) * | 2020-10-09 | 2022-04-11 | Genomtec Spółka Akcyjna | Zestaw starterów, skład reagentów oraz metoda wykrywania bakterii atypowych |
CN114182031A (zh) * | 2021-12-22 | 2022-03-15 | 江苏猎阵生物科技有限公司 | 一种核酸探针及其应用 |
GB2620948A (en) * | 2022-07-26 | 2024-01-31 | Mast Group Ltd | Method and kit |
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ATE246360T1 (de) * | 1991-05-22 | 2003-08-15 | Dade Behring Marburg Gmbh | Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen |
JP2003510017A (ja) | 1999-06-22 | 2003-03-18 | インビトロジェン コーポレイション | 核酸の検出および識別のために改良されたプライマーおよび方法 |
US7998673B2 (en) | 2000-03-29 | 2011-08-16 | Lgc Limited | Hybridisation beacon and method of rapid sequence detection and discrimination |
EP1295941B1 (en) * | 2000-06-27 | 2009-12-16 | National Institute of Advanced Industrial Science and Technology | Novel nucleic acid probes and method of assaying nucleic acid by using the same |
US6635427B2 (en) * | 2000-08-11 | 2003-10-21 | University Of Utah Research Foundation | Single-labeled oligonucleotide probes for homogeneous nucleic acid sequence analysis |
GB0103424D0 (en) * | 2001-02-12 | 2001-03-28 | Chiron Spa | Gonococcus proteins |
US6960436B2 (en) | 2002-02-06 | 2005-11-01 | Epigenomics Ag | Quantitative methylation detection in DNA samples |
JP2004261017A (ja) | 2003-02-27 | 2004-09-24 | Arkray Inc | クラミジア・トラコマティスの検出方法およびそのためのキット |
KR100885177B1 (ko) | 2004-04-12 | 2009-02-23 | 학교법인 포항공과대학교 | 표적 dna 또는 rna 탐지용 올리고뉴클레오티드 |
GB0514889D0 (en) | 2005-07-20 | 2005-08-24 | Lgc Ltd | Oligonucleotides |
JP2007275006A (ja) | 2006-04-10 | 2007-10-25 | Hitachi High-Technologies Corp | 核酸検出用プローブ作製法 |
ES2433667T3 (es) * | 2007-10-19 | 2013-12-12 | Eiken Kagaku Kabushiki Kaisha | Método de amplificación de ácidos nucleicos, y reactivo y kit de reactivos para la utilización en el método |
US8900807B2 (en) * | 2008-02-25 | 2014-12-02 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Composition and methods for rapid detection of HIV by loop-mediated isothermal amplification (LAMP) |
CA2724638C (en) * | 2008-05-27 | 2020-02-18 | Dako Denmark A/S | Hybridization compositions and methods comprising a polar aprotic solvent |
JP5509075B2 (ja) * | 2008-12-16 | 2014-06-04 | アークレイ株式会社 | 核酸増幅のコントロールの検出方法およびその用途 |
CA2763584A1 (en) * | 2009-05-29 | 2010-12-02 | Phthisis Diagnostics | Advanced pathogen detection and screening |
JP5859274B2 (ja) * | 2010-10-29 | 2016-02-10 | アークレイ株式会社 | Egfr遺伝子の多型検出用プローブ、増幅用プライマーおよびその用途 |
JP2013074888A (ja) * | 2011-09-15 | 2013-04-25 | Arkray Inc | IL28B(rs8099917)とITPA(rs1127354)の変異を検出する方法 |
JP2013081450A (ja) * | 2011-09-27 | 2013-05-09 | Arkray Inc | 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用試薬キット |
US9121051B2 (en) * | 2011-10-31 | 2015-09-01 | Arkray, Inc. | Method of determining the abundance of a target nucleotide sequence of a gene of interest |
CN103975061A (zh) * | 2011-10-31 | 2014-08-06 | 荣研化学株式会社 | 靶核酸的检测方法 |
JP6153758B2 (ja) * | 2012-04-20 | 2017-06-28 | アークレイ株式会社 | 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット |
CN102703433B (zh) * | 2012-06-12 | 2014-10-08 | 中国水产科学研究院黄海水产研究所 | 基于多孔材料的核酸等温扩增试剂的保存方法及试剂 |
WO2014017187A1 (ja) * | 2012-07-25 | 2014-01-30 | ソニー株式会社 | 核酸増幅反応用試料の調製方法及び核酸増幅反応用試料の調製装置 |
JP2014093996A (ja) * | 2012-11-12 | 2014-05-22 | Sony Corp | 核酸等温増幅方法 |
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2013
- 2013-10-30 GB GBGB1319180.4A patent/GB201319180D0/en not_active Ceased
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2014
- 2014-10-30 SI SI201431495T patent/SI3063292T1/sl unknown
- 2014-10-30 ES ES14793265T patent/ES2773313T3/es active Active
- 2014-10-30 CA CA2926317A patent/CA2926317C/en active Active
- 2014-10-30 US US15/032,011 patent/US20160273029A1/en not_active Abandoned
- 2014-10-30 WO PCT/GB2014/053238 patent/WO2015063498A2/en active Application Filing
- 2014-10-30 AU AU2014343439A patent/AU2014343439A1/en not_active Abandoned
- 2014-10-30 LT LTEP14793265.1T patent/LT3063292T/lt unknown
- 2014-10-30 PL PL14793265T patent/PL3063292T3/pl unknown
- 2014-10-30 JP JP2016526138A patent/JP2016534722A/ja active Pending
- 2014-10-30 RU RU2016112354A patent/RU2668154C2/ru active
- 2014-10-30 RS RS20200151A patent/RS59988B1/sr unknown
- 2014-10-30 GB GB1419367.6A patent/GB2524603A/en not_active Withdrawn
- 2014-10-30 HU HUE14793265A patent/HUE048579T2/hu unknown
- 2014-10-30 PT PT147932651T patent/PT3063292T/pt unknown
- 2014-10-30 CN CN201480057385.3A patent/CN105899674A/zh active Pending
- 2014-10-30 DK DK14793265.1T patent/DK3063292T3/da active
- 2014-10-30 EP EP14793265.1A patent/EP3063292B1/en active Active
-
2016
- 2016-04-05 ZA ZA2016/02247A patent/ZA201602247B/en unknown
- 2016-04-27 SA SA516371023A patent/SA516371023B1/ar unknown
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2019
- 2019-01-10 US US16/245,190 patent/US11111523B2/en active Active
- 2019-07-25 JP JP2019136553A patent/JP6983201B2/ja active Active
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2020
- 2020-02-17 HR HRP20200264TT patent/HRP20200264T1/hr unknown
- 2020-02-17 CY CY20201100142T patent/CY1124064T1/el unknown
- 2020-12-24 AU AU2020294316A patent/AU2020294316B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CY1124064T1 (el) | 2022-03-24 |
PL3063292T3 (pl) | 2020-06-29 |
AU2020294316B2 (en) | 2023-02-02 |
GB2524603A (en) | 2015-09-30 |
JP2016534722A (ja) | 2016-11-10 |
JP6983201B2 (ja) | 2021-12-17 |
HRP20200264T1 (hr) | 2020-05-29 |
AU2014343439A1 (en) | 2016-04-21 |
ZA201602247B (en) | 2022-05-25 |
US20160273029A1 (en) | 2016-09-22 |
EP3063292B1 (en) | 2019-11-20 |
DK3063292T3 (da) | 2020-02-24 |
ES2773313T3 (es) | 2020-07-10 |
SI3063292T1 (sl) | 2020-03-31 |
WO2015063498A2 (en) | 2015-05-07 |
GB201419367D0 (en) | 2014-12-17 |
CA2926317A1 (en) | 2015-05-07 |
SA516371023B1 (ar) | 2021-01-12 |
RU2668154C2 (ru) | 2018-09-26 |
RS59988B1 (sr) | 2020-03-31 |
US11111523B2 (en) | 2021-09-07 |
GB201319180D0 (en) | 2013-12-11 |
PT3063292T (pt) | 2020-02-14 |
CA2926317C (en) | 2023-05-23 |
JP2019216722A (ja) | 2019-12-26 |
AU2020294316A1 (en) | 2021-04-15 |
US20190127785A1 (en) | 2019-05-02 |
CN105899674A (zh) | 2016-08-24 |
EP3063292A2 (en) | 2016-09-07 |
NZ719238A (en) | 2022-03-25 |
WO2015063498A3 (en) | 2015-07-16 |
RU2016112354A (ru) | 2017-12-01 |
LT3063292T (lt) | 2020-02-25 |
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