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HUE044594T2 - RNS készítmény immunterápiához - Google Patents

RNS készítmény immunterápiához

Info

Publication number
HUE044594T2
HUE044594T2 HUE13713356A HUE044594T2 HU E044594 T2 HUE044594 T2 HU E044594T2 HU E13713356 A HUE13713356 A HU E13713356A HU E044594 T2 HUE044594 T2 HU E044594T2
Authority
HU
Hungary
Prior art keywords
immunotherapy
rna formulation
rna
formulation
Prior art date
Application number
Other languages
English (en)
Inventor
Ugur Sahin
Heinrich Haas
Sebastian Kreiter
Mustafa Diken
Daniel Fritz
Martin Meng
Lena Kranz
Kerstin Reuter
Original Assignee
Biontech Rna Pharmaceuticals Gmbh
Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biontech Rna Pharmaceuticals Gmbh, Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh filed Critical Biontech Rna Pharmaceuticals Gmbh
Publication of HUE044594T2 publication Critical patent/HUE044594T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A61K48/0033—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being non-polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HUE13713356 2012-03-26 2013-03-25 RNS készítmény immunterápiához HUE044594T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/001319 WO2013143555A1 (en) 2012-03-26 2012-03-26 Rna formulation for immunotherapy

Publications (1)

Publication Number Publication Date
HUE044594T2 true HUE044594T2 (hu) 2019-11-28

Family

ID=48044720

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE18171522A HUE052485T2 (hu) 2012-03-26 2013-03-25 RNA készítmény immunterápiára
HUE13713356 HUE044594T2 (hu) 2012-03-26 2013-03-25 RNS készítmény immunterápiához

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE18171522A HUE052485T2 (hu) 2012-03-26 2013-03-25 RNA készítmény immunterápiára

Country Status (19)

Country Link
US (3) US10485884B2 (hu)
JP (4) JP6279545B2 (hu)
CN (2) CN109331176B (hu)
AU (3) AU2013242512B2 (hu)
BR (1) BR112014022562A8 (hu)
CA (2) CA3088428C (hu)
DK (1) DK2830593T3 (hu)
ES (2) ES2719480T3 (hu)
HK (1) HK1202060A1 (hu)
HR (1) HRP20201578T1 (hu)
HU (2) HUE052485T2 (hu)
LT (2) LT2830593T (hu)
MX (3) MX2014011466A (hu)
NZ (1) NZ628328A (hu)
PT (2) PT2830593T (hu)
RS (1) RS61002B1 (hu)
SI (1) SI3427723T1 (hu)
TR (1) TR201904758T4 (hu)
WO (2) WO2013143555A1 (hu)

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CN109331176A (zh) 2019-02-15
BR112014022562A8 (pt) 2022-10-11
JP6596478B2 (ja) 2019-10-23
LT2830593T (lt) 2019-06-25
JP2019031571A (ja) 2019-02-28
JP2018024704A (ja) 2018-02-15
RS61002B1 (sr) 2020-11-30
US20150086612A1 (en) 2015-03-26
AU2013242512A1 (en) 2014-08-28
US10485884B2 (en) 2019-11-26
MX2014011466A (es) 2015-06-03
WO2013143683A1 (en) 2013-10-03
MX2020011696A (es) 2020-12-10
AU2017279565A1 (en) 2018-01-18
HK1202060A1 (en) 2015-09-18
AU2020202152A1 (en) 2020-04-16
JP6832904B2 (ja) 2021-02-24
ES2719480T3 (es) 2019-07-10
CA3088428C (en) 2023-08-01
US20200085974A1 (en) 2020-03-19
HRP20201578T1 (hr) 2021-03-05
WO2013143555A1 (en) 2013-10-03
AU2013242512B2 (en) 2018-01-18
CA2864253A1 (en) 2013-10-03
AU2020202152B2 (en) 2022-12-22
JP6279545B2 (ja) 2018-02-14
CA2864253C (en) 2020-09-29
ES2823239T3 (es) 2021-05-06
JP7096282B2 (ja) 2022-07-05
WO2013143683A8 (en) 2013-12-12
AU2013242512A8 (en) 2014-09-18
TR201904758T4 (tr) 2019-04-22
AU2017279565B2 (en) 2020-01-30
HUE052485T2 (hu) 2021-05-28
DK2830593T3 (en) 2019-04-23
MX2020011781A (es) 2020-11-24
CA3088428A1 (en) 2013-10-03
PT2830593T (pt) 2019-05-06
CN104302276A (zh) 2015-01-21

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