[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HRP20050143B1 - Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat - Google Patents

Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat

Info

Publication number
HRP20050143B1
HRP20050143B1 HRP20050143AA HRP20050143A HRP20050143B1 HR P20050143 B1 HRP20050143 B1 HR P20050143B1 HR P20050143A A HRP20050143A A HR P20050143AA HR P20050143 A HRP20050143 A HR P20050143A HR P20050143 B1 HRP20050143 B1 HR P20050143B1
Authority
HR
Croatia
Prior art keywords
medicaments containing
trihydrate
hydrochloride trihydrate
containing vardenafil
vardenafil hydrochloride
Prior art date
Application number
HRP20050143AA
Other languages
English (en)
Inventor
Peter Serno
Alfons Grunenberg
Andreas Ohm
Rainer Bellinghausen
Eimer Vollers
Jan-Olav Henck
Original Assignee
Bayer Intellectual Property Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29796385&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20050143(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Intellectual Property Gmbh filed Critical Bayer Intellectual Property Gmbh
Publication of HRP20050143A2 publication Critical patent/HRP20050143A2/xx
Publication of HRP20050143B1 publication Critical patent/HRP20050143B1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Izum se odnosi na postupak za proizvodnju lijekova koji sadržavaju vardenafil hidroklorid, u biti kao trihidrat u čvrstom obliku, i na lijekove koji se mogu dobiti u skladu s tom metodom.
HRP20050143AA 2002-07-16 2005-02-15 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat HRP20050143B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10232113A DE10232113A1 (de) 2002-07-16 2002-07-16 Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
PCT/EP2003/007093 WO2004006894A1 (de) 2002-07-16 2003-07-03 Vardenafil hydrochlorid trihydrat enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
HRP20050143A2 HRP20050143A2 (en) 2005-06-30
HRP20050143B1 true HRP20050143B1 (hr) 2014-01-31

Family

ID=29796385

Family Applications (3)

Application Number Title Priority Date Filing Date
HRP20050143AA HRP20050143B1 (hr) 2002-07-16 2005-02-15 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat
HRP20120418AA HRP20120418B1 (hr) 2002-07-16 2012-05-16 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat
HRP20131002AA HRP20131002A2 (hr) 2002-07-16 2013-10-23 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat

Family Applications After (2)

Application Number Title Priority Date Filing Date
HRP20120418AA HRP20120418B1 (hr) 2002-07-16 2012-05-16 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat
HRP20131002AA HRP20131002A2 (hr) 2002-07-16 2013-10-23 Lijekovi koji sadržavaju vardenafil hidroklorid trihidrat

Country Status (32)

Country Link
US (2) US8273876B2 (hr)
EP (2) EP1523303B1 (hr)
JP (2) JP5173113B2 (hr)
KR (2) KR101552418B1 (hr)
CN (2) CN1681481B (hr)
AT (1) ATE538777T1 (hr)
AU (1) AU2003249942B2 (hr)
BR (1) BRPI0305559B8 (hr)
CA (2) CA2492747C (hr)
CU (1) CU23473B7 (hr)
CY (2) CY1112460T1 (hr)
DE (1) DE10232113A1 (hr)
DK (2) DK2272505T3 (hr)
EC (1) ECSP055541A (hr)
ES (2) ES2378358T3 (hr)
HK (1) HK1084019A1 (hr)
HR (3) HRP20050143B1 (hr)
HU (1) HUE032362T2 (hr)
IL (2) IL166162A (hr)
LT (1) LT2272505T (hr)
MA (1) MA27320A1 (hr)
MX (1) MXPA05000554A (hr)
NO (2) NO335434B1 (hr)
NZ (1) NZ537698A (hr)
PH (1) PH12012501171A1 (hr)
PL (1) PL223341B1 (hr)
PT (2) PT2272505T (hr)
RU (1) RU2349306C2 (hr)
SI (2) SI1523303T1 (hr)
UA (1) UA85542C2 (hr)
WO (1) WO2004006894A1 (hr)
ZA (1) ZA200500268B (hr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU738675B2 (en) * 1997-11-12 2001-09-20 Bayer Intellectual Property Gmbh 2-phenyl-substituted imidazotriazinones as phosphodiesterase inhibitors
IL158738A0 (en) * 2001-05-09 2004-05-12 Bayer Healthcare Ag Novel use of 2-phenyl-substituted imidazotriazinones
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE102004023069A1 (de) * 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
MX2008000087A (es) * 2005-06-23 2008-03-18 Schering Corp Formulaciones orales rapidamente absorbentes de inhibidores de la fosfodiesterasa 5.
WO2007010337A2 (de) * 2005-07-15 2007-01-25 Proxomed Medizintechnik Gmbh Verwendung von phosphodiesterase typ 5-hemmern für die prävention und behandlung von adipositas, sowie abgabesysteme für dieselben
AU2006299232A1 (en) * 2005-09-29 2007-04-12 Bayer Schering Pharma Aktiengesellschaft PDE inhibitors and combinations thereof for the treatment of urological disorders
US7977478B2 (en) * 2006-03-13 2011-07-12 Dr. Reddy's Laboratories Limited Polymorphic forms of vardenafil
DE102007027067A1 (de) 2007-06-12 2008-12-18 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat
KR20100029762A (ko) * 2007-06-13 2010-03-17 바이엘 쉐링 파마 악티엔게젤샤프트 청력 장애 치료용 ｐｄｅ 억제제
DE102007034741A1 (de) * 2007-07-25 2009-01-29 Siemens Ag Elektrische Maschine mit Öffnungen im Lagerschildunterteil
PL390079A1 (pl) 2009-12-30 2011-07-04 Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna Sposób otrzymywania wardenafilu i jego izolacji jako soli z kwasem cytrynowym oraz krystaliczna postać tej soli
CZ303877B6 (cs) 2011-11-24 2013-06-05 Zentiva, K.S. Zpusob prípravy a izolace solí vardenafilu s kyselinami
CN103372014B (zh) * 2012-04-26 2015-10-21 齐鲁制药有限公司 一种能快速溶出、稳定的盐酸伐地那非口服固体制剂及其制备方法
CZ307091B6 (cs) * 2012-09-14 2018-01-10 Zentiva, K.S. Stabilní farmaceutický přípravek obsahující Vardenafil hydrochlorid
EP3043793B1 (en) 2013-11-19 2021-01-06 Siga Technologies Inc. Rehydration of micronized tecovirimat monohydrate
US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
PL223869B1 (pl) 2013-12-16 2016-11-30 Starogardzkie Zakłady Farm Polpharma Spółka Akcyjna Sposób otrzymywania wardenafilu i jego soli
CN111655229A (zh) 2017-12-20 2020-09-11 卡里亚制药控股有限公司 包含伐地那非的薄膜制剂、其制备方法及其用途
JP7336241B2 (ja) * 2019-04-02 2023-08-31 富士化学工業株式会社 バルデナフィル含有錠剤の製造方法
CN110507626B (zh) * 2019-09-19 2020-08-18 山东创新药物研发有限公司 一种稳定的盐酸伐地那非三水合物药物组合物的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB790762A (en) * 1953-08-28 1958-02-19 Arthur Poole A hydrate of lignocaine hydrochloride and process for making it
WO2001019357A2 (de) * 1999-09-15 2001-03-22 Bayer Aktiengesellschaft Kombinationspräparat zur behandlung von sexueller dysfunktion
US6362178B1 (en) * 1997-11-12 2002-03-26 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2705715A (en) 1952-10-29 1955-04-05 American Cyanamid Co Purine compounds and methods of preparing the same
CH367510A (de) 1957-11-27 1963-02-28 Ciba Geigy Verfahren zur Herstellung neuer Sulfonamide
GB1051734A (hr) 1963-01-16
GB1042471A (en) 1963-01-16 1966-09-14 Ilford Ltd Penta-azaindenes, their production and use in photographic emulsions
US3169129A (en) 1963-05-10 1965-02-09 American Cyanamid Co 2-ortho-hydroxy-phenyl-4-(3h)-quinazolinones
USRE26565E (en) 1966-03-02 1969-04-29 Table iii
GB1338235A (en) 1970-12-15 1973-11-21 May & Baker Ltd Azapurinones
GB1493685A (en) 1970-12-15 1977-11-30 May & Baker Ltd 8-azapurinones
BE791025A (fr) 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
US4052390A (en) 1973-06-12 1977-10-04 May & Baker Limited Azapurinones
US4060615A (en) 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
GB1561345A (en) 1976-10-22 1980-02-20 May & Baker Ltd 8 - azapuring - 6 - ones
US4159330A (en) 1976-11-02 1979-06-26 Carlo Erba S.P.A. 2-Disubstituted phenyl-3,4-dihydro-4-oxo-quinazoline derivatives and process for their preparation
DK109578A (da) 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
GB1584461A (en) 1977-03-25 1981-02-11 Allen & Hanburys Ltd Imidazotriazines imidazotriazinones and pharmaceutical compositions containing them
US4308384A (en) 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
DE3166627D1 (en) 1980-12-12 1984-11-15 Thomae Gmbh Dr K Pyrimidones, their preparation and medicines containing them
US4431440A (en) 1981-02-20 1984-02-14 American Cyanamid Company Method to alter or control the development and/or the life cycle of various plant species
JPS60246396A (ja) 1984-05-22 1985-12-06 Sankyo Co Ltd 酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類
US4666908A (en) 1985-04-05 1987-05-19 Warner-Lambert Company 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use
CA1303037C (en) 1987-02-02 1992-06-09 Smith Kline & French Laboratories Limited Purinone derivatives as bronchodilators vasodilators and anti-allergic agents
US5254571A (en) 1988-04-21 1993-10-19 Smith Kline & French Laboratories Ltd. Chemical compounds
GB8814352D0 (en) 1988-06-16 1988-07-20 Smith Kline French Lab Chemical compounds
EP0347146B1 (en) 1988-06-16 1993-09-01 Smith Kline & French Laboratories Limited Fused pyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them
US5075310A (en) 1988-07-01 1991-12-24 Smith Kline & French Laboratories, Ltd. Pyrimidone derivatives as bronchodilators
US4923874A (en) 1988-07-21 1990-05-08 G. D. Searle & Co. Use of 8-azapurin-6-one derivatives for control of hypertension
GB8817651D0 (en) 1988-07-25 1988-09-01 Smith Kline French Lab Chemical compounds
GB8827988D0 (en) 1988-11-30 1989-01-05 Smith Kline French Lab Chemical compounds
GB8928346D0 (en) 1989-12-15 1990-02-21 Smith Kline French Lab Chemical compounds
WO1991015194A1 (en) 1990-04-11 1991-10-17 The Upjohn Company Taste masking of ibuprofen by fluid bed coating
US5250534A (en) 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
GB9013750D0 (en) 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9114760D0 (en) 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents
US5316906A (en) 1991-08-23 1994-05-31 Molecular Probes, Inc. Enzymatic analysis using substrates that yield fluorescent precipitates
GB9119704D0 (en) 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic agents
GB9121028D0 (en) 1991-10-03 1991-11-13 Pfizer Ltd Therapeutic agents
GB9126260D0 (en) 1991-12-11 1992-02-12 Pfizer Ltd Therapeutic agents
US5294612A (en) 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
IL105553A (en) 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage forms consisting of a porous network of matrix that releases a substance that dissipates rapidly in water
GB9213623D0 (en) 1992-06-26 1992-08-12 Pfizer Ltd Therapeutic agents
US5734053A (en) 1992-06-26 1998-03-31 Pfizer Inc Purinone antianginal agents
GB9218322D0 (en) 1992-08-28 1992-10-14 Pfizer Ltd Therapeutic agents
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
GB9312210D0 (en) 1993-06-14 1993-07-28 Smithkline Beecham Plc Chemical compounds
GB9315017D0 (en) 1993-07-20 1993-09-01 Glaxo Lab Sa Chemical compounds
WO1995007267A1 (fr) 1993-09-10 1995-03-16 Eisai Co., Ltd. Compose de quinazoline
US6210714B1 (en) * 1993-11-23 2001-04-03 Euro-Celtique S.A. Immediate release tablet cores of acetaminophen having sustained-release coating
JPH07206857A (ja) * 1993-12-28 1995-08-08 Synthelabo Sa アルフゾシン塩酸塩の二水和物
US6143746A (en) 1994-01-21 2000-11-07 Icos Corporation Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
US5374053A (en) * 1994-01-21 1994-12-20 Heidelberger Druckmaschinen Ag Device for changing the transport position of products
US5556847A (en) 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
GB9423911D0 (en) 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
CN1080721C (zh) * 1995-07-03 2002-03-13 旭化成株式会社 1－(5－异喹啉磺酰基)高哌嗪盐酸盐水合物
GB9514464D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Medicaments
TW438608B (en) * 1995-08-02 2001-06-07 Hisamitsu Pharmaceutical Co A tablet containing anion exchange resin
JP3182685B2 (ja) * 1995-09-01 2001-07-03 北陸製薬株式会社 水和物結晶及びその製造方法
DE19540642A1 (de) 1995-11-01 1997-05-07 Stief Christian Georg Priv Doz Verwendung von Inhibitoren der Phosphodiesterase bei der Behandlung von Prostataerkrankungen
GB9612514D0 (en) 1996-06-14 1996-08-14 Pfizer Ltd Novel process
KR20000048540A (ko) * 1996-09-24 2000-07-25 피터 지. 스트링거 코팅된 입자 제제
US6548490B1 (en) 1997-10-28 2003-04-15 Vivus, Inc. Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
DE19812462A1 (de) 1998-03-23 1999-09-30 Bayer Ag 2-[2-Ethoxy-5(4-ethyl-piperazin-1-sulfonyl) -phenyl]-5-methyl-7-prophyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on Dihydrochlorid
US6221402B1 (en) 1997-11-20 2001-04-24 Pfizer Inc. Rapidly releasing and taste-masking pharmaceutical dosage form
EP0945134A1 (de) * 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
GT199900061A (es) 1998-05-15 2000-10-14 Pfizer Formulaciones farmaceuticas.
DE19827640A1 (de) 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
CA2346350C (en) 1998-10-05 2008-01-08 Eisai Co., Ltd. Intraoral quickly disintegrating tablets
FR2785538B1 (fr) 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
AU3574500A (en) 1999-03-25 2000-10-16 Yuhan Corporation Rapidly disintegrable tablet for oral administration
JP2001106674A (ja) * 1999-05-13 2001-04-17 Nikken Chem Co Ltd 塩酸イピダクリン水和物の製造方法
IL137429A0 (en) 1999-07-28 2001-07-24 Pfizer Prod Inc Methods and compsitions for treating diseases and conditions of the eye
US6284270B1 (en) 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
US6075028A (en) 1999-09-23 2000-06-13 Graham; Richard Method of treating Tourette's syndrome and related CNS disorders
GB9923968D0 (en) 1999-10-11 1999-12-15 Pfizer Ltd Therapeutic agents
US6503908B1 (en) 1999-10-11 2003-01-07 Pfizer Inc Pharmaceutically active compounds
TW200400821A (en) 1999-11-02 2004-01-16 Pfizer Pharmaceutical composition (II) useful for treating or preventing pulmonary hypertension in a patient
BR0017043A (pt) 1999-12-24 2003-01-07 Bayer Ag Imidazo[1,3,5]triazinonas e sua aplicação
US6362478B1 (en) * 2000-02-14 2002-03-26 General Electric Company Radiation detector signal pulse clipping
AU2001257146B2 (en) 2000-04-19 2006-11-30 Johns Hopkins University Methods for prevention and treatment of gastrointestinal disorders
EP1301186A1 (en) 2000-07-19 2003-04-16 Lavipharm Laboratories, Inc. Sildenafil citrate solid dispersions having high water solubility
JP2004505054A (ja) 2000-08-01 2004-02-19 バイエル　アクチェンゲゼルシャフト 知覚を改善する医薬品としての選択的ｐｄｅ２インヒビター
ES2220789T3 (es) 2000-10-30 2004-12-16 Lupin Limited Composicion de cefuroxima axetilo de liberacion lenta que se desintegra rapidamente.
US20020091129A1 (en) 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
IN192750B (hr) 2000-12-15 2004-05-15 Ranbaxy Lab Ltd
DE10063108A1 (de) 2000-12-18 2002-06-20 Bayer Ag Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
JP2004520389A (ja) 2001-02-08 2004-07-08 ファルマシア・コーポレーション 性的不全の治療のための早期効果発現薬剤
CA2437754C (en) 2001-02-15 2010-05-18 Tanabe Seiyaku Co., Ltd. Tablets quickly disintegrated in oral cavity
FR2823668B1 (fr) 2001-04-20 2004-02-27 Ethypharm Lab Prod Ethiques Comprimes effervescents orodispersibles
IL158738A0 (en) 2001-05-09 2004-05-12 Bayer Healthcare Ag Novel use of 2-phenyl-substituted imidazotriazinones
AU2002255321B2 (en) 2001-05-10 2007-05-17 Astellas Pharma Inc. Tablets quickly disintegrating in the oral cavity and process for producing the same
CA2419089A1 (en) 2001-07-27 2003-03-05 Tatsuki Shinoda Composition comprises sustained-release fine particles for quick-disintegrating tablets in the buccal cavity and manufacturing method thereof
FR2831820B1 (fr) 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
GB0204771D0 (en) 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
US7939102B2 (en) 2002-06-07 2011-05-10 Torrent Pharmaceuticals Ltd. Controlled release formulation of lamotrigine
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
SE0202365D0 (sv) 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
GB0219516D0 (en) 2002-08-21 2002-10-02 Phoqus Ltd Fast dissolving and taste masked oral dosage form comprising sildenafil
DE10325813B4 (de) 2003-06-06 2007-12-20 Universitätsklinikum Freiburg Prophylaxe und/oder Therapie bei der portalen Hypertonie
WO2004110411A2 (fr) 2003-06-06 2004-12-23 Ethypharm Comprime orodispersible multicouche
US6980922B2 (en) * 2003-10-09 2005-12-27 Computational Biodynamics, Llc Computer simulation model for determining damage to the human central nervous system
JP3841804B2 (ja) 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
EP1744740A4 (en) 2004-04-27 2009-06-17 Medicinova Inc PHENOXYALKYCARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
AU2005299490C1 (en) 2004-10-21 2012-01-19 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
EP1817009A2 (en) 2004-11-24 2007-08-15 Spi Pharma, Inc. Orally disintegrating compositions
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
MX2008000087A (es) 2005-06-23 2008-03-18 Schering Corp Formulaciones orales rapidamente absorbentes de inhibidores de la fosfodiesterasa 5.
JP5074190B2 (ja) 2005-09-02 2012-11-14 富士化学工業株式会社 口腔内速崩壊性錠剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB790762A (en) * 1953-08-28 1958-02-19 Arthur Poole A hydrate of lignocaine hydrochloride and process for making it
US6362178B1 (en) * 1997-11-12 2002-03-26 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
WO2001019357A2 (de) * 1999-09-15 2001-03-22 Bayer Aktiengesellschaft Kombinationspräparat zur behandlung von sexueller dysfunktion

Also Published As

Publication number Publication date
WO2004006894A1 (de) 2004-01-22
SI2272505T1 (sl) 2017-01-31
DK2272505T3 (en) 2017-01-23
NO20141272L (no) 2005-02-02
NO335434B1 (no) 2014-12-15
CY1112460T1 (el) 2015-12-09
CN102210689A (zh) 2011-10-12
BRPI0305559B8 (pt) 2021-05-25
HRP20120418B1 (hr) 2018-01-26
IL166162A (en) 2014-05-28
CA2492747C (en) 2013-02-12
PT1523303E (pt) 2012-03-08
NZ537698A (en) 2006-10-27
CN1681481B (zh) 2010-12-15
RU2005103820A (ru) 2005-08-10
MA27320A1 (fr) 2005-05-02
UA85542C2 (ru) 2009-02-10
US8273876B2 (en) 2012-09-25
CN1681481A (zh) 2005-10-12
BR0305559A (pt) 2004-09-28
KR20130137723A (ko) 2013-12-17
KR20100137572A (ko) 2010-12-30
HRP20120418A2 (hr) 2012-06-30
IL166162A0 (en) 2006-01-15
AU2003249942A1 (en) 2004-02-02
ES2378358T3 (es) 2012-04-11
KR101552418B1 (ko) 2015-09-10
ATE538777T1 (de) 2012-01-15
ES2609593T3 (es) 2017-04-21
CY1118394T1 (el) 2017-06-28
HRP20131002A2 (hr) 2014-03-28
DE10232113A1 (de) 2004-01-29
PL223341B1 (pl) 2016-10-31
EP2272505A1 (de) 2011-01-12
HUE032362T2 (en) 2017-09-28
EP1523303B1 (de) 2011-12-28
BRPI0305559B1 (pt) 2019-09-03
JP2013063982A (ja) 2013-04-11
AU2003249942B2 (en) 2009-10-29
PT2272505T (pt) 2017-01-10
RU2349306C2 (ru) 2009-03-20
NO337043B1 (no) 2016-01-11
US20060111354A1 (en) 2006-05-25
EP1523303A1 (de) 2005-04-20
CN102210689B (zh) 2014-07-30
JP2005533836A (ja) 2005-11-10
DK1523303T3 (da) 2012-04-10
SI1523303T1 (sl) 2012-06-29
US20130078306A1 (en) 2013-03-28
PL374694A1 (en) 2005-10-31
CA2805600A1 (en) 2004-01-22
CA2805600C (en) 2018-12-18
PH12012501171A1 (en) 2016-01-11
EP2272505B1 (de) 2016-10-12
US8841446B2 (en) 2014-09-23
IL232538A0 (en) 2014-06-30
JP5173113B2 (ja) 2013-03-27
NO20050578L (no) 2005-02-02
HK1084019A1 (en) 2006-07-21
CA2492747A1 (en) 2004-01-22
HRP20050143A2 (en) 2005-06-30
MXPA05000554A (es) 2005-04-28
CU23473B7 (es) 2009-12-17
ZA200500268B (en) 2006-03-29
LT2272505T (lt) 2017-01-25
ECSP055541A (es) 2005-03-10

Similar Documents

Publication Publication Date Title
IL232538A0 (en) Medicines containing verzenfil hydrochloride trihydrate
AU2003231351A1 (en) Ultrasonic reactor and process for ultrasonic treatment of materials
MX270158B (es) Produccion de un producto de fermentacion.
SI1534237T1 (sl) Tablete, ki razpadejo v ustih in postopek za njihovo pripravo
AU2002314112A1 (en) Dietary supplements from wine vinasses and relevant production process
IL165723A0 (en) Process for the production of precipitated calciumcarbonates and product produced thereby
AU2003242236A1 (en) Rapidly disintegrating tablet and process for producing the same
PL376998A1 (pl) Produkt celulozowy i sposób jego wytwarzania
GB0229714D0 (en) Novel apparatus and method
AU2003303348A8 (en) Method for the production of a screw, and screw produced according to said method
MXPA03003169A (es) Alimento para la crianza de vacunas neonatos y su procedimiento de utilizacion.
WO2004014337A3 (en) A process for the preparation of dispersible tablet of cephalexin
AU2003292880A1 (en) A drop pill of treating and preventing from cardio-cerebral diseases and the process of producing thereof
AU2003228202A1 (en) Process for the production of nanoparticles, wherein low mechanical and sonic energies are used simultaneously
AU2002359561A1 (en) Absorbent composite product and process and apparatus for manufacture thereof
EP2003122A3 (en) Process for the production of 5-hydroxy-1-methylhydantoin
WO2004008835A3 (en) Method for treating cereal material with a screw transporter
AU2002349829A8 (en) Production process for plant biomass and its use
AU2002353446A1 (en) A process for the production of soybean sugars and the product produced thereof
HUP0401417A2 (en) Pharmaceutical composition having in creased activity for preventing and/or treating gastro-intestinal illnesses and process for its preparation
FI20020502A (fi) Menetelmä aktiivista happea sisältävän kalkkituotteen valmistamiseksi
AU2002233080A1 (en) Consumption product package, production process and apparatus
HUP0501127A2 (en) Pharmaceutical and food compositions for influencing expression of genes, and process for producing them
UA33561A (uk) Спосіб отримання високодисперсних порошків з рослинної сировини
ZA200105202B (en) Plant care product applicable by spray methods and process for the manufacture of said product.

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

PNAN Change of the applicant name, address/residence

Owner name: BAYER PHARMA AG, DE

PPPP Transfer of rights

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20190701

Year of fee payment: 17

ODRP Renewal fee for the maintenance of a patent

Payment date: 20200629

Year of fee payment: 18

ODRP Renewal fee for the maintenance of a patent

Payment date: 20210701

Year of fee payment: 19

ODRP Renewal fee for the maintenance of a patent

Payment date: 20220701

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20230703