[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HN2001000134A - Formas/hidratos poliformicas/ os de dihidrocloruro de n-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilproposi)-quinazolin-6-il]-acrimalida, procedimientos que tienen una accion de inhibicion irreversible de tirosina quinasa. - Google Patents

Formas/hidratos poliformicas/ os de dihidrocloruro de n-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilproposi)-quinazolin-6-il]-acrimalida, procedimientos que tienen una accion de inhibicion irreversible de tirosina quinasa.

Info

Publication number
HN2001000134A
HN2001000134A HN2001000134A HN2001000134A HN2001000134A HN 2001000134 A HN2001000134 A HN 2001000134A HN 2001000134 A HN2001000134 A HN 2001000134A HN 2001000134 A HN2001000134 A HN 2001000134A HN 2001000134 A HN2001000134 A HN 2001000134A
Authority
HN
Honduras
Prior art keywords
fluorphenylamine
morfolin
procedures
action
ilproposi
Prior art date
Application number
HN2001000134A
Other languages
English (en)
Inventor
Hubert Barth
Klaus Steiner
Scheider Simon
Dietmar Huls
Muhlenfeld Andreas
Manfred Westermayer
Original Assignee
Godecke Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Godecke Gmbh filed Critical Godecke Gmbh
Publication of HN2001000134A publication Critical patent/HN2001000134A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

SE DESCRIBEN FORMAS/HIDRATOS POLIFORM ICAS/OS DIHIDRICLORURO DE N-[4-(3-CLORO--FLUORFENILAMINO)-7-(3-MORFOLIN-4-ILPROPOXI)-QUINALOZIN-6-IL]-ACRILAMIDA, PROCEDIMIENTOS PARA SU PREPARACION Y SU USO EN LA OBTENCION DE MEDICAMENTOS QUE PRESENTAN UNA ACCION DE INHIBICION IRREVERSIBLE DE TIROSINA QUINASA.
HN2001000134A 2000-06-30 2001-06-26 Formas/hidratos poliformicas/ os de dihidrocloruro de n-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilproposi)-quinazolin-6-il]-acrimalida, procedimientos que tienen una accion de inhibicion irreversible de tirosina quinasa. HN2001000134A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10031971A DE10031971A1 (de) 2000-06-30 2000-06-30 Polymorphe Formen/Hydrate von N-[4-(3-Chlor-4-fluor-phenylamino)-7-(3-morpholin-4-yl-propoxy)-chinazolin-6-yl]-acrylamid Dihydrochlorid, Verfahren zu ihrer Herstellung sowie die Verwendung derselben zur Herstellung von Medikamenten mit irreversibler Tyrosinkinasehemmwirkung

Publications (1)

Publication Number Publication Date
HN2001000134A true HN2001000134A (es) 2001-09-11

Family

ID=7647397

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2001000134A HN2001000134A (es) 2000-06-30 2001-06-26 Formas/hidratos poliformicas/ os de dihidrocloruro de n-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilproposi)-quinazolin-6-il]-acrimalida, procedimientos que tienen una accion de inhibicion irreversible de tirosina quinasa.

Country Status (39)

Country Link
US (1) US20040034022A1 (es)
EP (1) EP1299363A1 (es)
JP (1) JP2004501902A (es)
KR (1) KR20030014403A (es)
CN (1) CN1438994A (es)
AP (1) AP2002002694A0 (es)
AR (1) AR031854A1 (es)
AU (1) AU2001283861A1 (es)
BG (1) BG107352A (es)
BR (1) BR0112082A (es)
CA (1) CA2412535A1 (es)
CZ (1) CZ20024037A3 (es)
DE (1) DE10031971A1 (es)
DZ (1) DZ3342A1 (es)
EA (1) EA005294B1 (es)
EC (1) ECSP024413A (es)
EE (1) EE200200714A (es)
GT (1) GT200100124A (es)
HN (1) HN2001000134A (es)
HR (1) HRP20021019A2 (es)
HU (1) HUP0300900A3 (es)
IL (1) IL152419A0 (es)
IS (1) IS6596A (es)
MA (1) MA26924A1 (es)
MX (1) MXPA03000101A (es)
NO (1) NO20026193L (es)
NZ (1) NZ522001A (es)
OA (1) OA12301A (es)
PA (1) PA8520801A1 (es)
PE (1) PE20020116A1 (es)
PL (1) PL365127A1 (es)
SK (1) SK17642002A3 (es)
SV (1) SV2002000517A (es)
TN (1) TNSN01090A1 (es)
UA (1) UA73588C2 (es)
UY (1) UY26803A1 (es)
WO (1) WO2002000630A1 (es)
YU (1) YU99802A (es)
ZA (1) ZA200209717B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100885835B1 (ko) 2004-05-06 2009-02-26 워너-램버트 캄파니 엘엘씨 4-페닐아미노-퀴나졸린-6-일-아미드
DE102006000122A1 (de) * 2006-03-17 2007-09-20 Aug. Winkhaus Gmbh & Co. Kg Schlüssel für einen Schließzylinder und Schließzylinder für einen solchen Schlüssel
JP6717947B2 (ja) * 2015-12-25 2020-07-08 シュアンチュー ファーマ カンパニー，リミティド キナゾリン誘導体の結晶及びその調製方法
CN108430990B (zh) * 2015-12-25 2020-08-25 山东轩竹医药科技有限公司 喹唑啉衍生物的晶体及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ295468B6 (cs) * 1996-04-12 2005-08-17 Warner-Lambert Company Polycyklické sloučeniny
DK1131304T3 (da) * 1998-11-19 2003-03-24 Warner Lambert Co N-[4-(3-chlor-4-fluor-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamid, en irreversibel inhibitor for tyrosin-kinaser

Also Published As

Publication number Publication date
PE20020116A1 (es) 2002-02-27
BG107352A (bg) 2003-07-31
EE200200714A (et) 2004-08-16
KR20030014403A (ko) 2003-02-17
UY26803A1 (es) 2002-01-31
MA26924A1 (fr) 2004-12-20
ECSP024413A (es) 2003-03-31
IL152419A0 (en) 2003-05-29
MXPA03000101A (es) 2004-09-13
SV2002000517A (es) 2002-07-03
UA73588C2 (en) 2005-08-15
AP2002002694A0 (en) 2002-12-31
YU99802A (sh) 2005-11-28
WO2002000630A1 (en) 2002-01-03
ZA200209717B (en) 2003-12-01
DE10031971A1 (de) 2002-01-10
EP1299363A1 (en) 2003-04-09
OA12301A (en) 2003-11-10
IS6596A (is) 2002-10-28
HRP20021019A2 (en) 2004-02-29
CA2412535A1 (en) 2002-01-03
PL365127A1 (en) 2004-12-27
EA005294B1 (ru) 2004-12-30
EA200300094A1 (ru) 2003-04-24
NZ522001A (en) 2004-07-30
DZ3342A1 (fr) 2002-01-03
HUP0300900A3 (en) 2004-01-28
CZ20024037A3 (cs) 2004-01-14
BR0112082A (pt) 2003-05-06
GT200100124A (es) 2002-06-27
US20040034022A1 (en) 2004-02-19
NO20026193L (no) 2003-01-27
PA8520801A1 (es) 2003-06-30
NO20026193D0 (no) 2002-12-23
HUP0300900A2 (hu) 2003-10-28
JP2004501902A (ja) 2004-01-22
SK17642002A3 (sk) 2004-05-04
TNSN01090A1 (fr) 2005-11-10
CN1438994A (zh) 2003-08-27
AU2001283861A1 (en) 2002-01-08
AR031854A1 (es) 2003-10-08

Similar Documents

Publication Publication Date Title
EE200200576A (et) Oksasooli derivaadid ja nende kasutamine türosiini kinaasi inhibiitoritena
EE05387B1 (et) KinasoliiniÁderivaadid,ÁnendeÁvalmistamismeetodÁjaÁkasutamine
EE200300475A (et) Türosiini kinaasi inhibiitorid, neid sisaldavad ravimkoostised ja nimetatud ühendid kasutamiseks haiguste ravis
NO20031375D0 (no) Farmasöytisk aktive sulfonamidderivater med både lipofile og ioniserbare grupper som inhibitorer av proteinjunkinaser
EE05383B1 (et) Polarlkarboksamiidhendid,ÁnendeÁvalmistamineÁjaÁkasutamineÁlipiiditasetÁalandavateÁtoimeainetenaÁningÁneidÁsisaldavÁfarmatseutilineÁkompositsioon
NO20023713D0 (no) 2-benzotiazolyl-urea-derivater samt anvendelse derav som proteinkinaseinhibitorer
NO20032438D0 (no) Orto- og metasubstituerte bis-arylforbindelser, deres fremstilling og anvendelse samt farmasöytiske preparater inneholdende forbindelsene
EE200200484A (et) Väikeseannuseline entekaviiripreparaat ja selle kasutamine
BR0100046B1 (pt) Copolímeros reticulados, solúveis em água ou intumescíveis em água, processo para sua preparação, seu uso e preparação cosmética e farmacêutica
ECSP034774A (es) Pirazolopirimmidinas como agentes terapeuticos
ECSP034773A (es) Pirazolopirimmidinas como agentes terapeuticos
BR0113494B1 (pt) processo para a preparaÇço de uma formulaÇço sàlida herbicida, e, uso de uma formulaÇço sàlida herbicida.
EE200300085A (et) Pürasooli derivaadid ja nende kasutamine proteiini kinaasi inhibiitoritena
BR9906904B1 (pt) composto bicìclico heteroaromático como inibidor de tirosina quinase de proteìna, formulação farmacêutica compreendendo o mesmo, e seu uso.
EE04237B1 (et) 4-(5-metüül-3-fenüülisoksasool-4-üül)benseensulfoonamiidi kristalliline vorm, selle kasutamine ja valmistamise meetod
EE200100568A (et) 6-alkenüül-, 6-alkünüül- ja 6-epoksüepotilooni derivaadid, nende valmistamismeetod ja kasutamine farmatseutilistes preparaatides
CL2004000208A1 (es) COMPOSICION FARMACEUTICA QUE COMPRENDE: i) UNA BASE LIQUIDA CON 50-300mg/100ml DE SUCRALOSA PARA DISIMULAR SABOR AMARGO DE UN ACTIVO Y II) AL MENOS UN ACTIVO SELECCIONADO ENTRE ANTIHISTAMINAS, DESCONGESTIONANTES, ANTITUSIVOS, EXPECTORANTES, ANTIBIOTI
BR0110979B1 (pt) combinaÇÕes de substÂncias ativas com propriedades inseticidas e acaricidas, processo para sua preparaÇço e aplicaÇço.
BRPI0414215A (pt) tienopirazóis
AR038207A1 (es) Composicion farmaceutica dispersable oralmente de agomelatina
UY27080A1 (es) Nuevas imidazotriazinonas sustituídas
EE200400028A (et) Ravimpreparaat, selle valmistamise meetod ja selle kasutamine meditsiinis
AR028588A1 (es) Forma de administracion farmaceutica para peptidos, procedimiento para su preparacion y uso
BR0210650A (pt) Tablete, e, uso do mesmo
HN2001000134A (es) Formas/hidratos poliformicas/ os de dihidrocloruro de n-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilproposi)-quinazolin-6-il]-acrimalida, procedimientos que tienen una accion de inhibicion irreversible de tirosina quinasa.