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HK1211579A1 - Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl- cyano-methyl)-amides inhibitors of athepsin 2--[221]-3-(--)- - Google Patents

Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl- cyano-methyl)-amides inhibitors of athepsin 2--[221]-3-(--)-

Info

Publication number
HK1211579A1
HK1211579A1 HK15112308.5A HK15112308A HK1211579A1 HK 1211579 A1 HK1211579 A1 HK 1211579A1 HK 15112308 A HK15112308 A HK 15112308A HK 1211579 A1 HK1211579 A1 HK 1211579A1
Authority
HK
Hong Kong
Prior art keywords
athepsin
aza
bicyclo
heptane
cyano
Prior art date
Application number
HK15112308.5A
Other languages
English (en)
Chinese (zh)
Inventor
Ralf Anderskewitz
Matthias Grauert
Marc Grundl
Peter Wilhelm Haebel
Thorsten Oost
Alexander Pautsch
Stefan Peters
Florian Binder
Viktor Vintonyak
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HK1211579A1 publication Critical patent/HK1211579A1/xx

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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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HK15112308.5A 2013-03-14 2015-12-15 Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl- cyano-methyl)-amides inhibitors of athepsin 2--[221]-3-(--)- HK1211579A1 (en)

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