[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HK1208460A1 - 蛋白激酶抑制劑 - Google Patents

蛋白激酶抑制劑

Info

Publication number
HK1208460A1
HK1208460A1 HK15109229.7A HK15109229A HK1208460A1 HK 1208460 A1 HK1208460 A1 HK 1208460A1 HK 15109229 A HK15109229 A HK 15109229A HK 1208460 A1 HK1208460 A1 HK 1208460A1
Authority
HK
Hong Kong
Prior art keywords
protein kinase
kinase inhibitors
inhibitors
protein
kinase
Prior art date
Application number
HK15109229.7A
Other languages
English (en)
Inventor
Alain Laurent
Yannick Rose
James B Jaquith
Original Assignee
Pharmascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2779184A external-priority patent/CA2779184A1/en
Priority claimed from CA2813299A external-priority patent/CA2813299A1/en
Application filed by Pharmascience Inc filed Critical Pharmascience Inc
Publication of HK1208460A1 publication Critical patent/HK1208460A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15109229.7A 2012-05-31 2015-09-18 蛋白激酶抑制劑 HK1208460A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2779184A CA2779184A1 (en) 2012-05-31 2012-05-31 Protein kinase inhibitors
CA2813299A CA2813299A1 (en) 2013-04-17 2013-04-17 Protein kinase inhibitors
PCT/CA2013/000513 WO2013177668A1 (en) 2012-05-31 2013-05-28 Protein kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1208460A1 true HK1208460A1 (zh) 2016-03-04

Family

ID=49672221

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109229.7A HK1208460A1 (zh) 2012-05-31 2015-09-18 蛋白激酶抑制劑

Country Status (11)

Country Link
US (1) US9796716B2 (zh)
EP (1) EP2855484A4 (zh)
JP (1) JP6175495B2 (zh)
KR (2) KR20190043648A (zh)
CN (1) CN104379586B (zh)
BR (1) BR112014029718A2 (zh)
CA (1) CA2874211A1 (zh)
HK (1) HK1208460A1 (zh)
IN (1) IN2014MN02338A (zh)
RU (1) RU2678767C2 (zh)
WO (1) WO2013177668A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2833867A1 (en) * 2013-11-21 2015-05-21 Pharmascience Inc. Protein kinase inhibitors
CA2834528A1 (en) * 2013-11-26 2015-05-26 Pharmascience Inc. Protein kinase inhibitors
KR102073797B1 (ko) * 2014-07-07 2020-02-05 지앙수 헨그루이 메디슨 컴퍼니 리미티드 단백질 키나제 저해제로서의 아미노피리다지논 화합물
GB201508747D0 (en) 2015-05-21 2015-07-01 Univ Edinburgh Compounds
CA3025813A1 (en) * 2015-05-27 2016-12-01 Gb005, Inc. Inhibitors of the tec kinase enzyme family
CN108290850A (zh) 2015-12-07 2018-07-17 Dic株式会社 聚合性化合物的制造方法
WO2017134685A2 (en) * 2016-02-02 2017-08-10 Sun Pharma Advanced Research Company Limited Novel hydrazino compounds as btk inhibitors
CN109369654A (zh) * 2018-11-20 2019-02-22 山东大学 1，3-二取代-4-氨基吡唑并嘧啶类化合物及其制备方法和应用
CN111454268B (zh) * 2019-01-18 2023-09-08 明慧医药（上海）有限公司 作为布鲁顿酪氨酸激酶抑制剂的环状分子
WO2023083373A1 (zh) * 2021-11-15 2023-05-19 微境生物医药科技(上海)有限公司 作为Src抑制剂的化合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2385747A1 (en) * 1999-09-17 2001-03-22 Gavin C. Hirst Pyrazolopyrimidines as therapeutic agents
JP2003509427A (ja) 1999-09-17 2003-03-11 アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー 治療剤としてのキナーゼ阻害剤
US6921763B2 (en) * 1999-09-17 2005-07-26 Abbott Laboratories Pyrazolopyrimidines as therapeutic agents
RU2223761C2 (ru) * 1999-12-27 2004-02-20 Джапан Тобакко Инк. Соединения с конденсированным кольцом и их использование в качестве лекарственных средств
AUPR392301A0 (en) 2001-03-23 2001-04-26 University Of Newcastle Research Associates Limited, The Protein phosphatase inhibitors
EP2258371A1 (en) * 2001-08-10 2010-12-08 Novartis AG Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia
PT2526771T (pt) * 2006-09-22 2017-02-27 Pharmacyclics Llc Inibidores de tirosina-cinase de bruton
EP2543375A1 (en) * 2007-03-28 2013-01-09 Pharmacyclics, Inc. Pyrrolo-pyrimidine analogues as inhibitors of bruton's tyrosine kinase
US7741330B1 (en) * 2009-10-12 2010-06-22 Pharmacyclics, Inc. Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
CA2777565C (en) * 2009-10-13 2019-06-18 Ligand Pharmaceuticals Inc. Hematopoietic growth factor mimetic diphenylamine small molecule compounds and their uses
JP6139782B2 (ja) * 2013-05-21 2017-05-31 チャンスー メドリューション リミテッド 置換ピラゾロピリミジン化合物、及びその薬学的に許容される塩、並びにこれらの溶媒和物、立体異性体、及び互変異性体、並びにこれらを含む医薬組成物
CN103787839B (zh) 2014-01-21 2015-12-02 苏州昊帆生物科技有限公司 合成2,3,4,5,6-五氟苯酚的方法

Also Published As

Publication number Publication date
KR20190043648A (ko) 2019-04-26
RU2014145285A (ru) 2016-07-20
JP6175495B2 (ja) 2017-08-02
US9796716B2 (en) 2017-10-24
WO2013177668A1 (en) 2013-12-05
CN104379586B (zh) 2018-01-16
IN2014MN02338A (zh) 2015-08-14
RU2678767C2 (ru) 2019-02-01
CA2874211A1 (en) 2013-12-05
CN104379586A (zh) 2015-02-25
KR101972990B1 (ko) 2019-04-26
EP2855484A4 (en) 2015-12-16
KR20150015527A (ko) 2015-02-10
BR112014029718A2 (pt) 2017-06-27
JP2015518009A (ja) 2015-06-25
US20150191473A1 (en) 2015-07-09
EP2855484A1 (en) 2015-04-08

Similar Documents

Publication Publication Date Title
HK1215577A1 (zh) 蛋白激酶抑制劑
HK1200451A1 (zh) 蛋白激酶抑制劑
HK1217198A1 (zh) 蛋白激酶抑制劑
HK1210775A1 (zh) 作為激酶抑制劑的咪唑並三嗪甲腈
EP2694517A4 (en) PROTEIN KINASE INHIBITORS
HK1208442A1 (zh) 作為 激酶抑制劑的取代的吡咯並嘧啶基氨基－苯並噻唑酮
HK1222647A1 (zh) 激酶抑制劑
EP2710007A4 (en) Kinase Inhibitors
ZA201306855B (en) Protein kinase inhibitors
HK1205507A1 (zh) 蛋白激酶抑制劑
EP2833889A4 (en) PROTEIN KINASE C HEMMER AND USES THEREOF
HK1209726A1 (zh) 蛋白激酶抑制劑
HK1218119A1 (zh) 蛋白激酶抑制劑
IL229028A0 (en) Kinase inhibitors
HK1208460A1 (zh) 蛋白激酶抑制劑
HK1199873A1 (zh) 激酶抑制劑
SG11201500973WA (en) Amino-quinolines as kinase inhibitors
IL230504A0 (en) Selective protein kinase inhibitors
EP2879679A4 (en) ANTIBACTERIAL PROTEIN KINASE INHIBITORS
HK1210036A1 (zh) 作為蛋白激酶抑制劑的氨基異喹啉衍生物