HK1248226A1 - 1,4二取代的咪唑衍生物 - Google Patents
1,4二取代的咪唑衍生物Info
- Publication number
- HK1248226A1 HK1248226A1 HK18107692.6A HK18107692A HK1248226A1 HK 1248226 A1 HK1248226 A1 HK 1248226A1 HK 18107692 A HK18107692 A HK 18107692A HK 1248226 A1 HK1248226 A1 HK 1248226A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- imidazole derivative
- substituted imidazole
- substituted
- derivative
- imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015125174 | 2015-06-22 | ||
JP2015244856 | 2015-12-16 | ||
PCT/JP2016/068423 WO2016208591A1 (ja) | 2015-06-22 | 2016-06-21 | 1,4-ジ置換イミダゾール誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1248226A1 true HK1248226A1 (zh) | 2018-10-12 |
Family
ID=57584875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18107692.6A HK1248226A1 (zh) | 2015-06-22 | 2018-06-14 | 1,4二取代的咪唑衍生物 |
Country Status (13)
Country | Link |
---|---|
US (3) | US10807945B2 (zh) |
EP (1) | EP3312170A4 (zh) |
JP (1) | JP6692354B2 (zh) |
KR (1) | KR20180028456A (zh) |
CN (1) | CN107922386B (zh) |
AU (1) | AU2016284398C1 (zh) |
CA (1) | CA2990583A1 (zh) |
HK (1) | HK1248226A1 (zh) |
PH (1) | PH12017502388A1 (zh) |
RU (1) | RU2741000C2 (zh) |
SG (1) | SG11201710695XA (zh) |
TW (1) | TW201713642A (zh) |
WO (1) | WO2016208591A1 (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016284398C1 (en) | 2015-06-22 | 2021-01-07 | Sumitomo Dainippon Pharma Co., Ltd. | 1,4-disubstituted imidazole derivative |
US10294237B2 (en) | 2015-06-22 | 2019-05-21 | Sumitomo Dainippon Pharma Co., Ltd. | Bicyclic heterocyclic amide derivative |
US10898469B2 (en) | 2016-02-26 | 2021-01-26 | Sumitomo Dainippon Pharma Co., Ltd. | Imidazolylamide derivative |
JP6775483B2 (ja) * | 2016-12-20 | 2020-10-28 | 大日本住友製薬株式会社 | 1,4−ジ置換イミダゾール誘導体からなる医薬 |
EP3560494A4 (en) * | 2016-12-20 | 2020-08-05 | Sumitomo Dainippon Pharma Co., Ltd. | MEDICINAL PRODUCT TARGETING A CARCINOUS STEM CELL |
US11434472B2 (en) | 2016-12-20 | 2022-09-06 | Sumitomo Pharma Co., Ltd. | Agent for removing undifferentiated iPS cells |
HUE062256T2 (hu) * | 2018-03-20 | 2023-10-28 | Sumitomo Pharma Co Ltd | Dihidrokromén-származékok |
CN112313224B (zh) * | 2018-04-06 | 2024-08-13 | 阿尔托斯实验室公司 | Atf6抑制剂和其用途 |
JP7287929B2 (ja) * | 2019-09-25 | 2023-06-06 | 住友ファーマ株式会社 | ジヒドロクロメン誘導体を含有する医薬 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5359664A (en) | 1976-11-10 | 1978-05-29 | Sumitomo Chem Co Ltd | Novel imidazole derivatives |
US4140788A (en) | 1976-11-10 | 1979-02-20 | Sumitomo Chemical Company, Limited | N-Substituted imidazolecarboxamide derivatives |
JPH11513382A (ja) * | 1995-10-20 | 1999-11-16 | ドクトル カルル トーマエ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 5員複素環化合物、これらの化合物を含む医薬品、それらの使用及びそれらの調製方法 |
KR20010021905A (ko) | 1997-07-15 | 2001-03-15 | 노미야마 아키히콰 | 신규인 푸린유도체 및 그 의약용도 |
EP1730119B1 (en) * | 2004-03-23 | 2008-06-25 | Pfizer Products Incorporated | Imidazole compounds for the treatment of neurodegenerative disorders |
SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
CA2597896A1 (en) * | 2005-02-16 | 2006-08-24 | Solvay Pharmaceuticals B.V. | 1h-imidazole derivatives as cannabinoid cb2 receptor modulators |
AR052666A1 (es) * | 2005-02-16 | 2007-03-28 | Solvay Pharm Bv | Derivados de 1h-imidazol como moduladores del receptor cannabinoide cb2 |
DE102005008183A1 (de) | 2005-02-23 | 2006-08-31 | Bayer Healthcare Ag | Heterocyclylamid-substituierte Imidazole |
GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
BRPI0620373A2 (pt) | 2005-12-23 | 2011-11-08 | Astrazeneca Ab | composto e sais farmaceuticamente e farmacologicamente aceitáveis dos mesmos, e enantiÈmeros do composto e sais dos mesmos, uso dos mesmos, opcionalmente em combinação com um agonista do receptor de gabab,e , composição farmaceutica |
WO2008073461A2 (en) | 2006-12-11 | 2008-06-19 | Wyeth | Ion channel modulators |
GB0722075D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
LT2688885T (lt) * | 2011-03-22 | 2016-09-12 | Bayer Intellectual Property Gmbh | N-(1,3,4-oksadiazol-2-il)arilkarboksamidai ir jų panaudojimas kaip herbicidų |
IN2014CN02949A (zh) * | 2011-10-18 | 2015-07-03 | Astellas Pharma Inc | |
CN106459071A (zh) | 2014-03-31 | 2017-02-22 | 波士顿生物技术公司 | 新的三环醌衍生物 |
GB201416754D0 (en) * | 2014-09-23 | 2014-11-05 | Mission Therapeutics Ltd | Novel compounds |
AU2016284398C1 (en) * | 2015-06-22 | 2021-01-07 | Sumitomo Dainippon Pharma Co., Ltd. | 1,4-disubstituted imidazole derivative |
-
2016
- 2016-06-21 AU AU2016284398A patent/AU2016284398C1/en not_active Ceased
- 2016-06-21 TW TW105119454A patent/TW201713642A/zh unknown
- 2016-06-21 SG SG11201710695XA patent/SG11201710695XA/en unknown
- 2016-06-21 WO PCT/JP2016/068423 patent/WO2016208591A1/ja active Application Filing
- 2016-06-21 EP EP16814361.8A patent/EP3312170A4/en not_active Withdrawn
- 2016-06-21 CA CA2990583A patent/CA2990583A1/en not_active Abandoned
- 2016-06-21 RU RU2018102087A patent/RU2741000C2/ru active
- 2016-06-21 US US15/507,188 patent/US10807945B2/en active Active
- 2016-06-21 CN CN201680048691.XA patent/CN107922386B/zh not_active Expired - Fee Related
- 2016-06-21 JP JP2017524927A patent/JP6692354B2/ja active Active
- 2016-06-21 KR KR1020187001708A patent/KR20180028456A/ko unknown
-
2017
- 2017-02-27 US US15/443,892 patent/US9828362B2/en active Active
- 2017-12-21 PH PH12017502388A patent/PH12017502388A1/en unknown
-
2018
- 2018-06-14 HK HK18107692.6A patent/HK1248226A1/zh unknown
-
2020
- 2020-10-16 US US17/073,175 patent/US11661397B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20180230085A1 (en) | 2018-08-16 |
TW201713642A (zh) | 2017-04-16 |
EP3312170A4 (en) | 2018-12-12 |
RU2018102087A (ru) | 2019-07-23 |
AU2016284398A1 (en) | 2018-02-01 |
PH12017502388A1 (en) | 2018-07-09 |
CA2990583A1 (en) | 2016-12-29 |
JPWO2016208591A1 (ja) | 2018-04-05 |
RU2018102087A3 (zh) | 2019-12-25 |
CN107922386B (zh) | 2021-04-02 |
KR20180028456A (ko) | 2018-03-16 |
CN107922386A (zh) | 2018-04-17 |
US20170166552A1 (en) | 2017-06-15 |
RU2741000C2 (ru) | 2021-01-22 |
SG11201710695XA (en) | 2018-01-30 |
US9828362B2 (en) | 2017-11-28 |
EP3312170A1 (en) | 2018-04-25 |
AU2016284398B2 (en) | 2020-08-06 |
US10807945B2 (en) | 2020-10-20 |
US20210171440A1 (en) | 2021-06-10 |
US11661397B2 (en) | 2023-05-30 |
WO2016208591A1 (ja) | 2016-12-29 |
AU2016284398C1 (en) | 2021-01-07 |
JP6692354B2 (ja) | 2020-05-13 |
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