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HK1254202A1 - 三唑衍生物 - Google Patents

三唑衍生物

Info

Publication number
HK1254202A1
HK1254202A1 HK18113342.8A HK18113342A HK1254202A1 HK 1254202 A1 HK1254202 A1 HK 1254202A1 HK 18113342 A HK18113342 A HK 18113342A HK 1254202 A1 HK1254202 A1 HK 1254202A1
Authority
HK
Hong Kong
Prior art keywords
triazole derivatives
triazole
derivatives
Prior art date
Application number
HK18113342.8A
Other languages
English (en)
Inventor
馬里烏斯‧赫納
于爾根‧維希曼
Original Assignee
豪夫邁‧羅氏有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 豪夫邁‧羅氏有限公司 filed Critical 豪夫邁‧羅氏有限公司
Publication of HK1254202A1 publication Critical patent/HK1254202A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK18113342.8A 2015-10-06 2018-10-18 三唑衍生物 HK1254202A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15188567 2015-10-06
PCT/EP2016/073589 WO2017060202A1 (en) 2015-10-06 2016-10-04 Triazole derivatives

Publications (1)

Publication Number Publication Date
HK1254202A1 true HK1254202A1 (zh) 2019-07-12

Family

ID=54266438

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113342.8A HK1254202A1 (zh) 2015-10-06 2018-10-18 三唑衍生物

Country Status (6)

Country Link
US (1) US10273217B2 (zh)
EP (1) EP3359537B1 (zh)
JP (1) JP6831376B2 (zh)
CN (1) CN108137566B (zh)
HK (1) HK1254202A1 (zh)
WO (1) WO2017060202A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3286182A1 (en) 2015-04-23 2018-02-28 F. Hoffmann-La Roche AG Tetrazole derivatives for use in the treatment of psychiatric disorders
EP3464246B1 (en) * 2016-05-27 2020-07-08 H. Hoffnabb-La Roche Ag Pyrazol compounds as eaat3 inhibitors
JP7068277B2 (ja) 2016-10-14 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー Ｅａａｔ３阻害剤としてのイミダゾール化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006151954A (ja) 2004-10-27 2006-06-15 Taisho Pharmaceut Co Ltd アスパラギン酸誘導体
WO2007042545A1 (en) 2005-10-14 2007-04-19 Neurosearch A/S Imidazole derivatives and their use for modulating the gaba-a receptor complex
JP5021734B2 (ja) * 2006-06-29 2012-09-12 エフ．ホフマン−ラ ロシュ アーゲー テトラゾール置換アリールアミド
CA2701214C (en) * 2007-10-04 2016-08-02 F. Hoffmann-La Roche Ag Tetrazole-substituted aryl amide derivatives and uses thereof
AU2008319308B2 (en) * 2007-10-31 2013-01-31 Merck Sharp & Dohme Corp. P2X3, receptor antagonists for treatment of pain
ES2541662T3 (es) * 2007-12-17 2015-07-23 F. Hoffmann-La Roche Ag Derivados arilamida sustituidos con triazol y utilización de los mismos como antagonistas de receptores purinérgicos P2X3 y/o P2X2/3
EP2234976B1 (en) 2007-12-17 2013-04-10 F. Hoffmann-La Roche AG Novel pyrazole-substituted arylamides
JP5318882B2 (ja) 2007-12-17 2013-10-16 エフ．ホフマン−ラ ロシュ アーゲー 新規なイミダゾール置換アリールアミド
TW201006801A (en) 2008-07-18 2010-02-16 Lilly Co Eli Imidazole carboxamides
US20110237578A1 (en) * 2008-09-18 2011-09-29 Zhi-Liang Wei Amide compounds, compositions and uses thereof
JP5592388B2 (ja) 2008-10-31 2014-09-17 メルク・シャープ・アンド・ドーム・コーポレーション 疼痛治療用のｐ２ｘ３受容体アンタゴニスト技術分野
EP2411001B1 (en) * 2009-03-23 2018-01-17 Merck Sharp & Dohme Corp. P2x3, receptor antagonists for treatment of pain
EP3286182A1 (en) * 2015-04-23 2018-02-28 F. Hoffmann-La Roche AG Tetrazole derivatives for use in the treatment of psychiatric disorders
WO2016193235A1 (en) 2015-06-04 2016-12-08 F. Hoffmann-La Roche Ag Imidazole derivatives
JP6754828B2 (ja) 2015-08-12 2020-09-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ピリジン及びピリミジン誘導体
JP6849668B2 (ja) 2015-10-28 2021-03-24 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ピリジン又はピリミジン誘導体

Also Published As

Publication number Publication date
US10273217B2 (en) 2019-04-30
US20180237401A1 (en) 2018-08-23
WO2017060202A1 (en) 2017-04-13
CN108137566A (zh) 2018-06-08
EP3359537A1 (en) 2018-08-15
JP6831376B2 (ja) 2021-02-17
JP2018531253A (ja) 2018-10-25
CN108137566B (zh) 2021-05-25
EP3359537B1 (en) 2020-03-25

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