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HK1017852A1 - Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters - Google Patents

Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters

Info

Publication number
HK1017852A1
HK1017852A1 HK99102949A HK99102949A HK1017852A1 HK 1017852 A1 HK1017852 A1 HK 1017852A1 HK 99102949 A HK99102949 A HK 99102949A HK 99102949 A HK99102949 A HK 99102949A HK 1017852 A1 HK1017852 A1 HK 1017852A1
Authority
HK
Hong Kong
Prior art keywords
fatty acid
acid esters
aqueous suspensions
hydroxyrisperidone fatty
hydroxyrisperidone
Prior art date
Application number
HK99102949A
Other languages
English (en)
Inventor
Marc Karel Jozef Francois
Roger Carolus August Embrechts
Herman Karel Borghijs
Johan Monbaliu
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8224016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1017852(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1017852A1 publication Critical patent/HK1017852A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK99102949A 1996-05-20 1999-07-10 Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters HK1017852A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201429 1996-05-20
PCT/EP1997/002504 WO1997044039A1 (en) 1996-05-20 1997-05-12 Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters

Publications (1)

Publication Number Publication Date
HK1017852A1 true HK1017852A1 (en) 1999-12-03

Family

ID=8224016

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102949A HK1017852A1 (en) 1996-05-20 1999-07-10 Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters

Country Status (38)

Country Link
US (1) US6077843A (sk)
EP (1) EP0904081B1 (sk)
JP (1) JP3274687B2 (sk)
KR (1) KR100358373B1 (sk)
CN (1) CN1093762C (sk)
AR (1) AR007194A1 (sk)
AT (1) ATE208619T1 (sk)
AU (1) AU715572B2 (sk)
BG (1) BG62684B1 (sk)
BR (1) BR9706824B8 (sk)
CA (1) CA2236691C (sk)
CY (2) CY2270B1 (sk)
CZ (1) CZ291284B6 (sk)
DE (2) DE69708284T2 (sk)
DK (1) DK0904081T3 (sk)
EA (1) EA000536B1 (sk)
EE (1) EE03594B1 (sk)
ES (1) ES2167745T3 (sk)
FR (1) FR11C0035I2 (sk)
HK (1) HK1017852A1 (sk)
HR (1) HRP970276B1 (sk)
HU (2) HU224025B1 (sk)
ID (1) ID16927A (sk)
IL (1) IL124551A (sk)
LU (1) LU91842I2 (sk)
MX (1) MX9804816A (sk)
MY (1) MY126302A (sk)
NO (2) NO315931B1 (sk)
NZ (1) NZ330369A (sk)
PL (1) PL188309B1 (sk)
PT (1) PT904081E (sk)
SI (1) SI0904081T1 (sk)
SK (1) SK284013B6 (sk)
TR (1) TR199800923T2 (sk)
TW (1) TW487572B (sk)
UA (1) UA61898C2 (sk)
WO (1) WO1997044039A1 (sk)
ZA (1) ZA974331B (sk)

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UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
EP1056443B1 (en) * 1998-02-25 2004-05-06 Abbott Laboratories Butorphanol sustained release formulations
AU5489299A (en) * 1998-08-18 2000-03-14 Sepracor, Inc. Use of hydroxyrisperidone for the manufacture of a medicament for the treatment and prevention of psychoses, emesis and symptoms of withdrawal from alcohol and nicotine
PL198797B1 (pl) 1999-03-31 2008-07-31 Janssen Pharmaceutica Nv Zastosowanie wstępnie żelowanej skrobi
US6495164B1 (en) 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
NZ524554A (en) * 2000-08-14 2005-07-29 Teva Pharma Preparation of risperidone
US7666445B2 (en) * 2000-10-20 2010-02-23 The Trustees Of The University Of Pennsylvania Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use
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ES2293039T3 (es) * 2002-07-29 2008-03-16 Alza Corporation Procedimiento y formas de dosificacion para el suministro controlado de paliperidona.
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
GB0322994D0 (en) * 2003-10-01 2003-11-05 Novartis Ag Organic compounds
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US8329203B2 (en) * 2004-01-12 2012-12-11 The Trustees Of The University Of Pennsylvania Drug-containing implants and methods of use thereof
US8221778B2 (en) * 2005-01-12 2012-07-17 The Trustees Of The University Of Pennsylvania Drug-containing implants and methods of use thereof
US20080305140A1 (en) * 2004-01-12 2008-12-11 University Of Pennsylvania Long-Term Delivery Formulations and Methods of Use Thereof
ES2245252B1 (es) * 2004-06-15 2007-03-01 Farmalider, S.A. Solucion acuosa de risperidona para administracion oral.
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PL116330U1 (en) 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US7682356B2 (en) 2006-08-09 2010-03-23 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies for use therein
BRPI0809837A2 (pt) * 2007-04-19 2014-11-11 Youxin Li "composto para tratamento de distúrbios mentais, saldo do composto para tratamento de distúrbios mentais, composição farmacéutica e uso do composto para tratamento de distúrbios mentais"
PL2157967T3 (pl) 2007-04-23 2013-06-28 Intarcia Therapeutics Inc Formulacje zawiesinowe peptydów insulinotropowych i ich zastosowania
US20090076035A1 (en) * 2007-09-15 2009-03-19 Protia, Llc Deuterium-enriched paliperidone
US9439906B2 (en) * 2007-12-19 2016-09-13 Janssen Pharmaceutica Nv Dosing regimen associated with long acting injectable paliperidone esters
US20090209757A1 (en) * 2008-01-10 2009-08-20 Santiago Ini Processes for the preparation and purification of paliperidone palmitate
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
JP5744735B2 (ja) 2008-09-04 2015-07-08 アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc 非水性担体を用いた徐放性製剤
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WO2011074017A1 (en) * 2009-12-17 2011-06-23 Alkem Laboratories Ltd. A novel process for the preparation of paliperidone
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WO2013046225A2 (en) * 2011-08-10 2013-04-04 Glenmark Generics Limited Process for the preparation of paliperidone palmitate
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TWI754643B (zh) 2016-05-16 2022-02-11 美商因塔希亞治療公司 升糖素受體選擇性多肽和彼之使用方法
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
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DK4025189T3 (da) 2020-11-30 2024-06-10 Janssen Pharmaceutica Nv Doseringsskemaer i forbindelse med Injicerbare paliperidonformuleringer med forlænget frigivelse
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HUP2100259A1 (hu) 2021-07-07 2023-01-28 Richter Gedeon Nyrt Cariprazine tartalmú szabályozott hatóanyag-leadású injekciós készítmények
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Also Published As

Publication number Publication date
CA2236691C (en) 2007-01-02
EE03594B1 (et) 2002-02-15
CN1093762C (zh) 2002-11-06
TW487572B (en) 2002-05-21
HUS1100013I1 (hu) 2017-03-28
MY126302A (en) 2006-09-29
CA2236691A1 (en) 1997-11-27
DE122011100027I1 (de) 2011-11-17
UA61898C2 (en) 2003-12-15
TR199800923T2 (xx) 1999-09-21
DE69708284D1 (de) 2001-12-20
NO981984D0 (no) 1998-04-30
KR100358373B1 (ko) 2003-02-11
HRP970276B1 (en) 2002-04-30
HRP970276A2 (en) 1998-04-30
NZ330369A (en) 2000-04-28
HUP9901319A2 (hu) 1999-08-30
BG62684B1 (bg) 2000-05-31
SK284013B6 (sk) 2004-08-03
NO981984L (no) 1998-11-19
MX9804816A (es) 1998-10-31
JP3274687B2 (ja) 2002-04-15
EA199800531A1 (ru) 1998-12-24
ATE208619T1 (de) 2001-11-15
AU2955997A (en) 1997-12-09
IL124551A0 (en) 1998-12-06
ZA974331B (en) 1998-11-19
SK62098A3 (en) 2000-04-10
CY2011011I2 (el) 2016-12-14
DK0904081T3 (da) 2002-02-25
KR19990067603A (ko) 1999-08-25
EA000536B1 (ru) 1999-10-28
WO1997044039A1 (en) 1997-11-27
PT904081E (pt) 2002-04-29
NO2011015I1 (no) 2011-09-19
FR11C0035I1 (sk) 2011-07-10
BR9706824A (pt) 1999-03-23
PL188309B1 (pl) 2005-01-31
BR9706824B8 (pt) 2015-02-18
JP2000513718A (ja) 2000-10-17
IL124551A (en) 2001-08-26
BG102443A (en) 1999-06-30
HU224025B1 (hu) 2005-05-30
US6077843A (en) 2000-06-20
FR11C0035I2 (fr) 2013-08-16
CZ140198A3 (cs) 1999-04-14
ES2167745T3 (es) 2002-05-16
PL327995A1 (en) 1999-01-04
CZ291284B6 (cs) 2003-01-15
ID16927A (id) 1997-11-20
CN1206347A (zh) 1999-01-27
NO315931B1 (no) 2003-11-17
EP0904081A1 (en) 1999-03-31
AR007194A1 (es) 1999-10-13
LU91842I2 (fr) 2011-09-20
EP0904081B1 (en) 2001-11-14
DE69708284T2 (de) 2002-07-25
HUP9901319A3 (en) 1999-11-29
SI0904081T1 (en) 2002-04-30
EE9800136A (et) 1998-10-15
AU715572B2 (en) 2000-02-03
CY2270B1 (en) 2003-07-04
NO2011015I2 (no) 2013-03-11
CY2011011I1 (el) 2016-12-14

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Effective date: 20170511