[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HK1086487A1 - Alpha-aminoamide derivatives useful as antimigraine agents - Google Patents

Alpha-aminoamide derivatives useful as antimigraine agents

Info

Publication number
HK1086487A1
HK1086487A1 HK06106511.1A HK06106511A HK1086487A1 HK 1086487 A1 HK1086487 A1 HK 1086487A1 HK 06106511 A HK06106511 A HK 06106511A HK 1086487 A1 HK1086487 A1 HK 1086487A1
Authority
HK
Hong Kong
Prior art keywords
alpha
antimigraine agents
derivatives useful
aminoamide derivatives
aminoamide
Prior art date
Application number
HK06106511.1A
Other languages
English (en)
Inventor
Patricia Salvati
Marcello Calabresi
Dho L Luciano
Orietta Veneroni
Piero Melloni
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of HK1086487A1 publication Critical patent/HK1086487A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
HK06106511.1A 2003-01-16 2006-06-07 Alpha-aminoamide derivatives useful as antimigraine agents HK1086487A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03000921A EP1438956A1 (fr) 2003-01-16 2003-01-16 Dérivés alpha-aminoamides en tant qu'agents antimigraine
PCT/EP2003/012889 WO2004062655A1 (fr) 2003-01-16 2003-11-18 Derives alpha-aminoamides utiles en tant qu'antimigraineux

Publications (1)

Publication Number Publication Date
HK1086487A1 true HK1086487A1 (en) 2006-09-22

Family

ID=32524140

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06106511.1A HK1086487A1 (en) 2003-01-16 2006-06-07 Alpha-aminoamide derivatives useful as antimigraine agents

Country Status (21)

Country Link
US (2) US7709523B2 (fr)
EP (2) EP1438956A1 (fr)
JP (1) JP4885455B2 (fr)
KR (1) KR101049694B1 (fr)
CN (1) CN100418517C (fr)
AT (1) ATE380026T1 (fr)
AU (1) AU2003279399B8 (fr)
BR (1) BRPI0317795B8 (fr)
CA (1) CA2510514C (fr)
CY (1) CY1107274T1 (fr)
DE (1) DE60317935T2 (fr)
DK (1) DK1585510T3 (fr)
ES (1) ES2295658T3 (fr)
HK (1) HK1086487A1 (fr)
MX (1) MXPA05007339A (fr)
NO (1) NO333610B1 (fr)
NZ (1) NZ541117A (fr)
PT (1) PT1585510E (fr)
RU (1) RU2336077C2 (fr)
SI (1) SI1585510T1 (fr)
WO (1) WO2004062655A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
ES2253579T3 (es) * 2001-09-03 2006-06-01 Newron Pharmaceuticals S.P.A. Composicion farmaceutica que comprende gabapentina o un analogo suyo y una alfa-aminoamida y su uso analgesico.
US20070276046A1 (en) * 2003-08-25 2007-11-29 Patricia Salvati Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents
RS51411B (en) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. USE (R) - (HALOBENZYLOXY) BENZYLAMINO-PROPANAMIDE AS SELECTIVE MODULATORS OF SODIUM AND / OR CALCIUM CHANNELS
PT1963280E (pt) 2005-12-22 2016-02-02 Newron Pharm Spa Derivados de 2-feniletilamino como cálcio e/ou moduladores do canal de sódio
AU2007263328C1 (en) * 2006-06-19 2012-09-06 Newron Pharmaceuticals S.P.A. Process for the production of 2- [4 - ( 3- and 2-fluorobenzyloxy) benzylamino] propan amides
FR2903985B1 (fr) 2006-07-24 2008-09-05 Sanofi Aventis Sa Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
MX2009013119A (es) 2007-06-15 2010-03-04 Newron Pharm Spa Derivados de 2-[2-(fenil)etilamino]alcanamida sustituidos y su uso como moduladores del canal de sodio y/o potasio.
JP5460613B2 (ja) 2007-12-11 2014-04-02 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー 高純度を有する２−［４−（３−または２−フルオロベンジルオキシ）ベンジルアミノ］プロパンアミドの製造方法
EP2314569A1 (fr) 2009-10-22 2011-04-27 Merck Patent GmbH Nouvelles formules polymorphiques de sel de mesylate (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide, et son procédé de fabrication
EA021389B1 (ru) * 2010-04-27 2015-06-30 Ньюрон Фармасьютикалс С.П.А. Способ получения метансульфонатных солей ралфинамида или их r-энантиомеров
WO2015102390A1 (fr) * 2013-12-30 2015-07-09 이화여자대학교 산학협력단 Nouveau dérivé d'amide ou sel pharmaceutiquement acceptable de celui-ci, procédé de préparation de celui-ci, et composition pharmaceutique pour prévenir ou traiter la douleur, le contenant
CN107522654B (zh) * 2016-06-21 2020-09-01 中国人民解放军军事医学科学院毒物药物研究所 新的α-氨基酰胺衍生物及其医药用途
CN112041296B (zh) * 2018-04-28 2023-12-29 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
CN112716927B (zh) * 2020-10-12 2022-10-14 复旦大学 α-氨基酰胺类化合物及其制备方法与应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3658967A (en) * 1966-06-23 1972-04-25 Ici Ltd Carboxylic acid derivatives for lowering the concentration of triglycerides in the blood
GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
CH480308A (de) * 1966-08-11 1969-10-31 Ciba Geigy Verfahren zur Herstellung von Thiosemicarbazid-Verbindungen
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
US4311853A (en) * 1979-02-06 1982-01-19 The Radiochemical Centre Limited Selenium derivatives of thyroxine and tri-iodothyronine
DE3050800C2 (fr) * 1979-03-22 1989-06-22 Continental Pharma Inc., Bruessel/Bruxelles, Be
US4267354A (en) * 1979-04-25 1981-05-12 E. R. Squibb & Sons, Inc. Substituted amides having antiinflammatory activity and intermediates
ZA805476B (en) 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
EP0144853B1 (fr) * 1983-11-21 1990-09-26 Fujisawa Pharmaceutical Co., Ltd. Dérivés semicarbazides, procédé pour leur préparation et compositions pharmaceutiques les contenant
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4839369A (en) 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
GB8714901D0 (en) * 1986-07-23 1987-07-29 Ici Plc Amide derivatives
GB2216515A (en) * 1988-03-04 1989-10-11 Nippon Shinyaku Co Ltd Acylphenol derivatives
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
DE3928488A1 (de) 1989-08-29 1991-03-07 Standard Elektrik Lorenz Ag Interferometrisches messsystem
DE69224861T2 (de) 1991-07-30 1998-08-06 Korea Res Inst Chem Tech Neue Phenylacetamidderivate und Verfahren zu ihrer Herstellung
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
GB9306886D0 (en) 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5475007A (en) * 1993-05-28 1995-12-12 The Regents Of The University Of California 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3 or 4-oximes and the use thereof
US5482964A (en) * 1994-10-11 1996-01-09 Warner-Lambert Company Substituted phenoxyhydroxypropyl amines as central nervous system agents
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
US5849737A (en) * 1995-04-14 1998-12-15 The Regents Of The University Of California Compositions and methods for treating pain
US5741818A (en) * 1995-06-07 1998-04-21 University Of Saskatchewan Semicarbazones having CNS activity and pharmaceutical preparations containing same
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9515411D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa N-(4-substituted-benzyl)-2-aminolactam derivatives
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain
JP4160136B2 (ja) * 1996-08-29 2008-10-01 武田薬品工業株式会社 縮合環状エーテル類、その製造法および剤
TW492957B (en) 1996-11-07 2002-07-01 Novartis Ag N-substituted 2-cyanopyrrolidnes
GB9625795D0 (en) 1996-12-12 1997-01-29 Smithkline Beecham Plc Novel treatment
GB9706730D0 (en) 1997-04-03 1997-05-21 Pharmacia & Upjohn Spa 2-[(3-substituted)-5-Isoxazolymethylaminojalkanamid derivatives
NZ500590A (en) 1997-04-22 2001-11-30 Cocensys Inc Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
ES2402104T3 (es) * 1997-11-21 2013-04-29 Purdue Neuroscience Company Uso de 2-aminoacetamidas sustituidas para el tratamiento o alivio de la ansiedad
GB9727521D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Substituted 2-benzylamino-2-phenyl-acetamide compounds
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
IL137671A0 (en) 1998-02-04 2001-10-31 Euro Celtique Sa Semicarbazide derivatives and pharmaceutical compositions containing the same
JP2000191533A (ja) * 1998-10-19 2000-07-11 Eisai Co Ltd 鎮痛剤
CA2345406A1 (fr) * 1998-10-19 2000-04-27 Eisai Co., Ltd. Analgesiques
US6281211B1 (en) * 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
YU68701A (sh) * 1999-03-26 2004-09-03 Euro-Celtique S.A. Aril supstituisani pirazoli, imidazoli, oksazoli, tiazoli i piroli i njihova upotreba
EP1169060B1 (fr) * 1999-04-09 2005-08-31 Euro-Celtique S.A. Composition de blocage du canal sodique et leur utilisation
ES2253579T3 (es) * 2001-09-03 2006-06-01 Newron Pharmaceuticals S.P.A. Composicion farmaceutica que comprende gabapentina o un analogo suyo y una alfa-aminoamida y su uso analgesico.
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
EP1588704A1 (fr) * 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Dérivés d'alpha-aminoamides utiles dans le traitement de l'acroparesthésie nocturne et des troubles de toxicomanie
RS51411B (en) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. USE (R) - (HALOBENZYLOXY) BENZYLAMINO-PROPANAMIDE AS SELECTIVE MODULATORS OF SODIUM AND / OR CALCIUM CHANNELS

Also Published As

Publication number Publication date
BRPI0317795B1 (pt) 2019-04-02
NO333610B1 (no) 2013-07-22
ES2295658T3 (es) 2008-04-16
NO20053780D0 (no) 2005-08-09
BR0317795A (pt) 2005-11-22
CN100418517C (zh) 2008-09-17
JP2006514060A (ja) 2006-04-27
KR20050094852A (ko) 2005-09-28
RU2336077C2 (ru) 2008-10-20
JP4885455B2 (ja) 2012-02-29
BRPI0317795B8 (pt) 2021-05-25
EP1585510A1 (fr) 2005-10-19
EP1438956A1 (fr) 2004-07-21
CA2510514A1 (fr) 2004-07-29
AU2003279399A1 (en) 2004-08-10
EP1585510B1 (fr) 2007-12-05
AU2003279399B8 (en) 2009-01-29
CN1738611A (zh) 2006-02-22
CY1107274T1 (el) 2012-11-21
MXPA05007339A (es) 2005-09-30
AU2003279399B2 (en) 2008-11-27
US20060079570A1 (en) 2006-04-13
DE60317935T2 (de) 2008-11-27
DE60317935D1 (de) 2008-01-17
CA2510514C (fr) 2011-07-26
ATE380026T1 (de) 2007-12-15
US7709523B2 (en) 2010-05-04
NZ541117A (en) 2008-02-29
SI1585510T1 (sl) 2008-04-30
RU2005125919A (ru) 2006-01-10
NO20053780L (no) 2005-10-13
PT1585510E (pt) 2008-02-28
WO2004062655A1 (fr) 2004-07-29
US20100267835A1 (en) 2010-10-21
DK1585510T3 (da) 2008-02-25
KR101049694B1 (ko) 2011-07-19

Similar Documents

Publication Publication Date Title
HK1086487A1 (en) Alpha-aminoamide derivatives useful as antimigraine agents
TW200510301A (en) Novel compounds
TW200510303A (en) Novel compounds
TW200407305A (en) Novel compounds
SE0202241D0 (sv) Novel Compounds
MY147478A (en) Microbiologically stabilised beer
TW200626068A (en) Active compounds for seed treatment
TNSN05045A1 (en) Indole or benzimidazole derivatives for modulating ikappab kinase
HK1119699A1 (en) Pyridopyrimidinone inhibitors of pi3kalpha
TW200738724A (en) Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
TW200510407A (en) Novel pyrrolodihydroisoquinolines as PDE 10 inhibitors
TW200744586A (en) Therapeutic compounds
NO20082136L (no) 1,5-substituerte indol-2-yl-amidderivater
IL189298A0 (en) 3.5-disubstituted phenyl-piperidines as modulators of dopamine meurotransmission
NO20082096L (no) Azaindol-2-karboksamidderivativer
WO2007047447A3 (fr) Analogues de compose diuretique ou de type diuretique
IL191751A0 (en) Pyrrolo[2,3-c]pyridine derivatives
GB0510143D0 (en) Novel compounds A1
TW200738143A (en) Use of arylanilides for seed treatment
SI1900362T1 (sl) Derivati alfa-aminoamida, uporabni pri zdravljenju odvisnosti
MXPA05013151A (es) 3-fluoro-piperidinas como antagonistas de n-metil-d-aspartato/nr2b.
EP1441724B8 (fr) Methodes pouvant augmenter des concentrations en testosterone endogene
TW200505435A (en) Treatment of ocular disorders
DE602007008947D1 (en) 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren
TW200815363A (en) KV1.5 potassium channel inhibitors

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20231117